James Galagan

Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis (2006)

Kahmann, Regine, Bölker, Michael, Ma, Li-Jun, Brefort, Thomas, Saville, Barry J, ...

Ustilago maydis is a ubiquitous pathogen of maize and a well-established model organism for the study of plant-microbe interactions. This basidiomycete fungus does not use aggressive virulence...

Comparative Genomic Characterization of Francisella tularensis Strains Belonging to Low and High Virulence Subspecies

Champion, Mia D., Zeng, Qiandong, Nix, Eli B., Nano, Francis E., Keim, Paul, Kodira, Chinnappa D., ...

Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in humans. It is caused by infection by a gram-negative bacterium, Francisella tularensis. In order to...

Pneumococcal Capsular Polysaccharide Structure Predicts Serotype Prevalence

Weinberger, Daniel M., Trzciński, Krzysztof, Lu, Ying-Jie, Bogaert, Debby, Brandes, Aaron, Galagan, James, ...

There are 91 known capsular serotypes of Streptococcus pneumoniae. The nasopharyngeal carriage prevalence of particular serotypes is relatively stable worldwide, but the host and bacterial factors...

Genomic Analysis of the Basal Lineage Fungus Rhizopus oryzae Reveals a Whole-Genome Duplication

Ma, Li-Jun, Ibrahim, Ashraf S., Skory, Christopher, Grabherr, Manfred G., Burger, Gertraud, Butler, Margi, ...

Rhizopus oryzae is the primary cause of mucormycosis, an emerging, life-threatening infection characterized by rapid angioinvasive growth with an overall mortality rate that exceeds 50%. As a...