Fine mapping of the human SCIDX1 locus at Xq12-13.1 (1993)
Markiewicz, Sophie, DiSanto, James P., Chelly, Jamel, Fairweather, NIicolas, Le Marec, Bernard, Griscelli, Claude, ...
Previous linkage analysis of families with X-linked severe combined immunodeficiency (SCIDX1) mapped this locus to a large region encompassing about 10 to 20 cM at Xq12–21. We have analyzed in...
Lantz, Olivier, Sharara, Lama I., Tilloy, Florence, Andersson, Åsa, DiSanto, James P.
In this report, we have assessed the lineage relationships and cytokine dependency of natural killer (NK) T cells compared with mainstream TCR-αβ T cells and NK cells. For this purpose, we studied...
Role of Different T Cell Receptors in the Development of Pre–T Cells
Buer, Jan, Aifantis, Iannis, DiSanto, James P., Fehling, Hans Joerg, Boehmer, Harald Von
The development of pre–T cells with productive TCR-β rearrangements can be mediated by each the pre–T cell receptor (pre-TCR), the TCR-αβ as well as the TCR-γδ, albeit by distinct...
The Common Cytokine Receptor γ Chain Controls Survival of γ/δ T Cells
Malissen, Marie, Pereira, Pablo, Gerber, David J., Malissen, Bernard, DiSanto, James P.
We have investigated the role of common γ chain (γc)-signaling pathways for the development of T cell receptor for antigen (TCR)-γ/δ T cells. TCR-γ/δ–bearing cells were absent from the adult...