James S. Friedman

Identification (2004)

Shigeo Yoshida A, James S. Friedman, Todd Carter, Shirley He, Edwin Oh, ...

− mouse retina:

Expression profiling of the developing and mature Nrl-/- mouse retina: Identification of retinal disease candidates and transcriptional regulatory targets of Nrl (2004)

Yoshida, Shigeo, Mears, Alan J., Friedman, James S., Carter, Todd, He, Shirley, Oh, Edwin, ...

The rod photoreceptor-specific neural retina leucine zipper protein Nrl is essential for rod differentiation and plays a critical role in regulating gene expression. In the mouse retina, rods account...

Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl (2004)

Yoshida, Shigeo, Mears, Alan J., Friedman, James S., Carter, Todd, He, Shirley, Oh, Edwin, ...

The rod photoreceptor-specific neural retina leucine zipper protein Nrl is essential for rod differentiation and plays a critical role in regulating gene expression. In the mouse retina, rods account...

Expression profiling of the developing and mature Nrl-/- mouse retina: Identification of retinal disease candidates and transcriptional regulatory targets of Nrl (2004)

Yoshida, Shigeo, Mears, Alan J., Friedman, James S., Carter, Todd, He, Shirley, Oh, Edwin, ...

The rod photoreceptor-specific neural retina leucine zipper protein Nrl is essential for rod differentiation and plays a critical role in regulating gene expression. In the mouse retina, rods account...

Protein localization in the human eye and genetic screen of opticin (2002)

Friedman, James S., Faucher, Mathieu, Hiscott, Paul, Biron, Vincent L., Malenfant, Mario, Turcotte, Pierre, ...

The opticin (OPTC) gene encodes a protein that is a member of the small leucine-rich repeat protein (SLRP) family. OPTC is located on chromosome 1q31–q32 within an age-related macular degeneration...

Recessive NRL mutations in patients with clumped pigmentary retinal degeneration and relative preservation of blue cone function

Nishiguchi, Koji M., Friedman, James S., Sandberg, Michael A., Swaroop, Anand, Berson, Eliot L., Dryja, Thaddeus P.

Mice lacking the transcription factor Nrl have no rod photoreceptors and an increased number of short-wavelength-sensitive cones. Missense mutations in NRL are associated with autosomal dominant...

Recessive NRL mutations in patients with clumped pigmentary retinal degeneration and relative preservation of blue cone function

Nishiguchi, Koji M., Friedman, James S., Sandberg, Michael A., Swaroop, Anand, Berson, Eliot L., Dryja, Thaddeus P.

Mice lacking the transcription factor Nrl have no rod photoreceptors and an increased number of short-wavelength-sensitive cones. Missense mutations in NRL are associated with autosomal dominant...

Retinopathy mutations in the bZIP protein NRL alter phosphorylation and transcriptional activity This article is a US Government work, and, as such, is in the public domain in the United States of America. Communicated by Peter Humphries

Kanda, Atsuhiro, Friedman, James S., Nishiguchi, Koji M., Swaroop, Anand

The transcription factor neural retina leucine zipper (NRL) is required for rod photoreceptor differentiation during mammalian retinal development. NRL interacts with CRX, NR2E3, and other...