James W. Ajioka

Publication List Details

Period

1998 - 2008

Number

23

Co-Authors

Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection (2008)

Hermes, Gretchen, Ajioka, James W, Kelly, Krystyna A, Mui, Ernest, Roberts, Fiona, Kasza, Kristen, ...

Abstract Background Worldwide, approximately two billion people are chronically infected with Toxoplasma gondii with largely unknown consequences. Methods To better understand long-term effects and...

Epigenomic Modifications Predict Active Promoters and Gene Structure in Toxoplasma gondii (2007)

Mathieu Gissot, Krystyna A. Kelly, James W. Ajioka, John M. Greally, Kami Kim

Mechanisms of gene regulation are poorly understood in Apicomplexa, a phylum that encompasses deadly human pathogens like Plasmodium and Toxoplasma. Initial studies suggest that epigenetic phenomena,...

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii (2006)

Khan, Asis, Böhme, Ulrike, Kelly, Krystyna A., Adlem, Ellen, Brooks, Karen, Simmonds, Mark, ...

Toxoplasma gondii is a globally distributed protozoan parasite that can infect virtually all warm-blooded animals and humans. Despite the existence of a sexual phase in the life cycle, T. gondii has...

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii (2006)

Khan, Asis, Böhme, Ulrike, Kelly, Krystyna A., Adlem, Ellen, Brooks, Karen, Simmonds, Mark, ...

Toxoplasma gondii is a globally distributed protozoan parasite that can infect virtually all warm-blooded animals and humans. Despite the existence of a sexual phase in the life cycle, T. gondii has...

Quality determination and the repair of poor quality spots in array experiments (2005)

Tom, Brian DM, Gilks, Walter R, Brooke-Powell, Elizabeth T, Ajioka, James W

Abstract Background A common feature of microarray experiments is the occurence of missing gene expression data. These missing values occur for a variety of reasons, in particular, because of the...

Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii (2005)

Khan, Asis, Taylor, Sonya, Su, Chunlei, Mackey, Aaron J., Boyle, Jon, Cole, Robert, ...

Toxoplasma gondii is a highly successful protozoan parasite in the phylum Apicomplexa, which contains numerous animal and human pathogens. T.gondii is amenable to cellular, biochemical, molecular and...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac,Frédéric, Sänger,Astrid, Neuhaus,Eva M., Stratmann,Rolf, Ajioka,James W., Toursel,Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac,Frédéric, Sänger,Astrid, Neuhaus,Eva M., Stratmann,Rolf, Ajioka,James W., Toursel,Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac, Frédéric, Sänger, Astrid, Neuhaus, Eva M., Stratmann, Rolf, Ajioka, James W., Toursel, Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac, Frédéric, Sänger, Astrid, Neuhaus, Eva M., Stratmann, Rolf, Ajioka, James W., Toursel, Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii

Su, Chunlei, Howe, Daniel K., Dubey, J. P., Ajioka, James W., Sibley, L. David

Strains of Toxoplasma gondii can be grouped into three predominant clonal lineages with members of the type I group being uniformly lethal in mice. To elucidate the basis of this extreme virulence, a...

Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii

Khan, Asis, Taylor, Sonya, Su, Chunlei, Mackey, Aaron J., Boyle, Jon, Cole, Robert, ...

Toxoplasma gondii is a highly successful protozoan parasite in the phylum Apicomplexa, which contains numerous animal and human pathogens. T.gondii is amenable to cellular, biochemical, molecular and...

Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii

Su, Chunlei, Howe, Daniel K., Dubey, J. P., Ajioka, James W., Sibley, L. David

Strains of Toxoplasma gondii can be grouped into three predominant clonal lineages with members of the type I group being uniformly lethal in mice. To elucidate the basis of this extreme virulence, a...

Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii

Khan, Asis, Taylor, Sonya, Su, Chunlei, Mackey, Aaron J., Boyle, Jon, Cole, Robert, ...

Toxoplasma gondii is a highly successful protozoan parasite in the phylum Apicomplexa, which contains numerous animal and human pathogens. T.gondii is amenable to cellular, biochemical, molecular and...

Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii

Boyle, Jon P., Rajasekar, Badri, Saeij, Jeroen P. J., Ajioka, James W., Berriman, Matthew, Paulsen, Ian, ...

Toxoplasma gondii, an obligate intracellular protozoan of the phylum Apicomplexa, is estimated to infect over a billion people worldwide as well as a great many other mammalian and avian hosts....

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii

Khan, Asis, Böhme, Ulrike, Kelly, Krystyna A., Adlem, Ellen, Brooks, Karen, Simmonds, Mark, ...

Toxoplasma gondii is a globally distributed protozoan parasite that can infect virtually all warm-blooded animals and humans. Despite the existence of a sexual phase in the life cycle, T. gondii has...

Epigenomic Modifications Predict Active Promoters and Gene Structure in Toxoplasma gondii

Gissot, Mathieu, Kelly, Krystyna A, Ajioka, James W, Greally, John M, Kim, Kami

Mechanisms of gene regulation are poorly understood in Apicomplexa, a phylum that encompasses deadly human pathogens like Plasmodium and Toxoplasma. Initial studies suggest that epigenetic phenomena,...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations, and a role in parasite division

Delbac, Frédéric, Sänger, Astrid, Neuhaus, Eva M., Stratmann, Rolf, Ajioka, James W., Toursel, Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Selection at a Single Locus Leads to Widespread Expansion of Toxoplasma gondii Lineages That Are Virulent in Mice

Khan, Asis, Taylor, Sonya, Ajioka, James W., Rosenthal, Benjamin M., Sibley, L. David

Pathogenicity differences among laboratory isolates of the dominant clonal North American and European lineages of Toxoplasma gondii are largely controlled by polymorphisms and expression differences...