James W. E. Rush

Myoadenylate deaminase deficiency does not affect muscle anaplerosis during exhaustive exercise in humans

Tarnopolsky, Mark A, Parise, Gianni, Gibala, Martin J, Graham, Terry E, Rush, James W E

Myoadenylate deaminase (AMPD) deficiency is present in 1–2 % of the population. In theory, this deficiency may alter exercise energy metabolism by impairing the purine nucleotide cycle (PNC) and...