Jan B. Koenderink

Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparumplasma membrane (2009)

Kavishe, Reginald A, Van Den Heuvel, Jeroen MW, Luty, Adrian JF, Russel, Frans GM, Koenderink, Jan B

Abstract Background The spread of drug resistance has been a major obstacle to the control of malaria. The mechanisms underlying drug resistance in malaria seem to be complex and multigenic. The...

High-affinity ouabain binding by a chimeric gastric H+,K+-ATPase containing transmembrane hairpins M3-M4 and M5-M6 of the α1-subunit of rat Na+,K+-ATPase

Koenderink, Jan B., Hermsen, Harm P. H., Swarts, Herman G. P.

Na+,K+-ATPase and gastric H+,K+-ATPase are two related enzymes that are responsible for active cation transport. Na+,K+-ATPase activity is inhibited specifically by ouabain, whereas H+,K+-ATPase is...

High-affinity ouabain binding by a chimeric gastric H+,K+-ATPase containing transmembrane hairpins M3-M4 and M5-M6 of the α1-subunit of rat Na+,K+-ATPase

Koenderink, Jan B., Hermsen, Harm P. H., Swarts, Herman G. P.

Na+,K+-ATPase and gastric H+,K+-ATPase are two related enzymes that are responsible for active cation transport. Na+,K+-ATPase activity is inhibited specifically by ouabain, whereas H+,K+-ATPase is...

Diverse Functional Consequences of Mutations in the Na+/K+-ATPase α2-Subunit Causing Familial Hemiplegic Migraine Type 2*

Tavraz, Neslihan N., Friedrich, Thomas, Dürr, Katharina L., Koenderink, Jan B., Bamberg, Ernst, Freilinger, Tobias, ...

Mutations in ATP1A2, the gene coding for the Na+/K+-ATPase α2-subunit, are associated with both familial hemiplegic migraine and sporadic cases of hemiplegic migraine. In this study, we examined the...

FXYD2 and Na,K-ATPase Expression in Isolated Human Proximal Tubular Cells: Disturbed Upregulation on Renal Hypomagnesemia?

Cairo, Edinio R., Swarts, Herman G. P., Wilmer, Martijn J. G., Levtchenko, Elena N., ...

Autosomal dominant renal hypomagnesemia (OMIM 154020), associated with hypocalciuria, has been linked to a 121G to A mutation in the FXYD2 gene. To gain insight into the molecular mechanisms linking...