Jan Mollenhauer

DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease (2007)

Renner, Marcus, Bergmann, Gaby, Krebs, Inge, End, Caroline, Lyer, Stefan, Hilberg, Frank, ...

BACKGROUND & AIMS: Impaired mucosal defense plays an important role in the pathogenesis of Crohn's disease (CD), one of the main subtypes of inflammatory bowel disease (IBD). Deleted in malignant...

Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant (2007)

Müller, Hanna, End, Caroline, Renner, Marcus, Helmke, Burkhard M, Gassler, Nikolaus, Weiss, Christel, ...

Abstract Background Deleted in Malignant Brain Tumors 1 (DMBT1) is a secreted scavenger receptor cysteine-rich protein that binds various bacteria and is thought to participate in innate pulmonary...

Deleted in Malignant Brain Tumors 1 is a versatile mucin-like molecule likely to play a differential role in digestive tract cancer (2001)

Mollenhauer, Jan, Herbertz, Stephan, Helmke, Burkhard, Kollender, Gaby, Krebs, Inge, Madsen, Jens, ...

Deleted in Malignant Brain Tumors 1 (DMBT1) has been proposed as a candidate tumor suppressor gene for brain, lung, and digestive tract cancer. In particular, alterations of the gene and/or a loss of...

Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D

Holmskov, Uffe, Mollenhauer, Jan, Madsen, Jens, Vitved, Lars, Grønlund, Jørn, Tornøe, Ida, ...

Surfactant protein D (SP-D) is an oligomeric C type lectin that promotes phagocytosis by binding to microbial surface carbohydrates. A 340-kDa glycoprotein (gp-340) has been shown to bind SP-D in the...

Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D

Holmskov, Uffe, Mollenhauer, Jan, Madsen, Jens, Vitved, Lars, Grønlund, Jørn, Tornøe, Ida, ...

Surfactant protein D (SP-D) is an oligomeric C type lectin that promotes phagocytosis by binding to microbial surface carbohydrates. A 340-kDa glycoprotein (gp-340) has been shown to bind SP-D in the...

Genetic Mapping in Mice Identifies DMBT1 as a Candidate Modifier of Mammary Tumors and Breast Cancer Risk

Blackburn, Anneke C., Hill, Linda Z., Roberts, Amy L., Wang, Jun, Aud, Dee, Jung, Jimmy, ...

Low-penetrance breast cancer susceptibility alleles seem to play a significant role in breast cancer risk but are difficult to identify in human cohorts. A genetic screen of 176 N2 backcross progeny...