Janci L. Chunn

Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts (2006)

Willems, Laura, Reichelt, Melissa Elizabeth, Molina, Jose G, Sun, Chun-Xiao, Chunn, Janci L, Ashton, Kevin John, ...

OBJECTIVE: Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...

Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts (2006)

Willems, Laura, Reichelt, Melissa Elizabeth, Molina, Jose G, Sun, Chun-Xiao, Chunn, Janci L, Ashton, Kevin John, ...

OBJECTIVE: Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...

Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts (2006)

Willems, Laura, Reichelt, Melissa Elizabeth, Molina, Jose G, Sun, Chun-Xiao, Chunn, Janci L, Ashton, Kevin John, ...

OBJECTIVE: Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...

Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts (2006)

Willems, Laura, Reichelt, Melissa Elizabeth, Molina, Jose G, Sun, Chun-Xiao, Chunn, Janci L, Ashton, Kevin John, ...

OBJECTIVE: Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...

Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts (2006)

Willems, Laura, Reichelt, Melissa E., Molina, Jose G., Sun, Chun-Xiao, Chunn, Janci L., Ashton, Kevin J., ...

Objective Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...

Adenosine mediates IL-13–induced inflammation and remodeling in the lung and interacts in an IL-13–adenosine amplification pathway

Blackburn, Michael R., Lee, Chun G., Young, Hays W.J., Zhu, Zhou, Chunn, Janci L., Kang, Min Jong, ...

IL-13 is an important mediator of inflammation and remodeling. We hypothesized that adenosine accumulation, alterations in adenosine receptors, and adenosine–IL-13 autoinduction are critical events...

Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury

Sun, Chun-Xiao, Zhong, Hongyan, Mohsenin, Amir, Morschl, Eva, Chunn, Janci L., Molina, Jose G., ...

Adenosine has been implicated in the pathogenesis of chronic lung diseases such as asthma and chronic obstructive pulmonary disease. In vitro studies suggest that activation of the A2B adenosine...

Adenosine mediates IL-13–induced inflammation and remodeling in the lung and interacts in an IL-13–adenosine amplification pathway

Blackburn, Michael R., Lee, Chun G., Young, Hays W.J., Zhu, Zhou, Chunn, Janci L., Kang, Min Jong, ...

IL-13 is an important mediator of inflammation and remodeling. We hypothesized that adenosine accumulation, alterations in adenosine receptors, and adenosine–IL-13 autoinduction are critical events...

Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury

Sun, Chun-Xiao, Zhong, Hongyan, Mohsenin, Amir, Morschl, Eva, Chunn, Janci L., Molina, Jose G., ...

Adenosine has been implicated in the pathogenesis of chronic lung diseases such as asthma and chronic obstructive pulmonary disease. In vitro studies suggest that activation of the A2B adenosine...

Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling

Mi, Tiejuan, Abbasi, Shahrzad, Zhang, Hong, Uray, Karen, Chunn, Janci L., Xia, Ling Wei, ...

Priapism, abnormally prolonged penile erection in the absence of sexual excitation, is associated with ischemia-mediated erectile tissue damage and subsequent erectile dysfunction. It is common among...