Tissue-specific variation in DNA methylation levels along human chromosome 1 (2009)
De Bustos, Cecilia, Ramos, Edward, Young, Janet M, Tran, Robert K, Menzel, Uwe, Langford, Cordelia F, ...
Abstract Background DNA methylation is a major epigenetic modification important for regulating gene expression and suppressing spurious transcription. Most methods to scan the genome in different...
Rudd, M. Katharine, Endicott, RaeLynn M., Friedman, Cynthia, Walker, Megan, Young, Janet M., Osoegawa, Kazutoyo, ...
Subtelomeres are concentrations of interchromosomal segmental duplications capped by telomeric repeats at the ends of chromosomes. The nature of the segments shared by different sets of human...
Young, Janet M., Kambere, Marijo, Trask, Barbara J., Lane, Robert P.
The V1R gene family comprises one of two types of putative pheromone receptors expressed in the mammalian vomeronasal organ (VNO). We searched the most recent mouse, rat, dog, chimpanzee, and human...
Young, Janet M., Kambere, Marijo, Trask, Barbara J., Lane, Robert P.
The V1R gene family comprises one of two types of putative pheromone receptors expressed in the mammalian vomeronasal organ (VNO). We searched the most recent mouse, rat, dog, chimpanzee, and human...
Correction for Volume 15, p. 231 (2005)
Young, Janet M., Kambere, Marijo, Trask, Barbara J., Lane, Robert P.
Young, Janet M, Shykind, Benjamin M, Lane, Robert P, Tonnes-Priddy, Lori, Ross, Joseph A, Walker, Megan, ...
Abstract Background The olfactory receptor gene family is one of the largest in the mammalian genome. Previous computational analyses have identified approximately 1,500 mouse olfactory receptors,...
The sense of smell: genomics of vertebrate odorant receptors (2002)
Young, Janet M., Trask, Barbara J.
Olfactory receptor (OR) proteins interact with odorant molecules in the nose, initiating a neuronal response that triggers the perception of a smell. The OR family is one of the largest known...
Different evolutionary processes shaped the mouse and human olfactory receptor gene families (2002)
Young, Janet M., Friedman, Cynthia, Williams, Eleanor M., Ross, Joseph A., Tonnes-Priddy, Lori, Trask, Barbara J.
We report a comprehensive comparative analysis of human and mouse olfactory receptor (OR) genes. The OR family is the largest mammalian gene family known. We identify ∼93% of an estimated...
Different evolutionary processes shaped the mouse and human olfactory receptor gene families (2002)
Young, Janet M., Friedman, Cynthia, Williams, Eleanor M., Ross, Joseph A., Tonnes-Priddy, Lori, Trask, Barbara J.
Young, Janet M, Shykind, Benjamin M, Lane, Robert P, Tonnes-Priddy, Lori, Ross, Joseph A, Walker, Megan, ...
Previous computational analyses have identified approximately 1,500 mouse olfactory receptors, but experimental evidence confirming olfactory function is available for very few receptors. A mouse...
Young, Janet M., Kambere, Marijo, Trask, Barbara J., Lane, Robert P.
The V1R gene family comprises one of two types of putative pheromone receptors expressed in the mammalian vomeronasal organ (VNO). We searched the most recent mouse, rat, dog, chimpanzee, and human...
Human subtelomeres are hot spots of interchromosomal recombination and segmental duplication
Linardopoulou, Elena V., Williams, Eleanor M., Fan, Yuxin, Friedman, Cynthia, Young, Janet M., Trask, Barbara J.
Human subtelomeres are polymorphic patchworks of inter-chromosomal segmental duplications at the ends of chromosomes. We provide evidence here that these patchworks arose recently through repeated...
Young, Janet M, Shykind, Benjamin M, Lane, Robert P, Tonnes-Priddy, Lori, Ross, Joseph A, Walker, Megan, ...
Previous computational analyses have identified approximately 1,500 mouse olfactory receptors, but experimental evidence confirming olfactory function is available for very few receptors. A mouse...
Young, Janet M., Kambere, Marijo, Trask, Barbara J., Lane, Robert P.
The V1R gene family comprises one of two types of putative pheromone receptors expressed in the mammalian vomeronasal organ (VNO). We searched the most recent mouse, rat, dog, chimpanzee, and human...
Degeneration of the Olfactory Guanylyl Cyclase D Gene during Primate Evolution
Young, Janet M., Waters, Hang, Dong, Cora, Fülle, Hans-Jürgen, Liman, Emily R.
Extensive Copy-Number Variation of the Human Olfactory Receptor Gene Family
Young, Janet M., Endicott, RaeLynn M., Parghi, Sean S., Walker, Megan, Kidd, Jeffrey M., Trask, Barbara J.
As much as a quarter of the human genome has been reported to vary in copy number between individuals, including regions containing about half of the members of the olfactory receptor (OR) gene...
Comparative sequence analysis of primate subtelomeres originating from a chromosome fission event
Rudd, M. Katharine, Endicott, RaeLynn M., Friedman, Cynthia, Walker, Megan, Young, Janet M., Osoegawa, Kazutoyo, ...
Subtelomeres are concentrations of interchromosomal segmental duplications capped by telomeric repeats at the ends of chromosomes. The nature of the segments shared by different sets of human...