MHC-linked and un-linked class I genes in the wallaby (2009)
Siddle, Hannah V, Deakin, Janine E, Coggill, Penny, Hart, Elizabeth, Cheng, Yuanyuan, Wong, Emily SW, ...
Abstract Background MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune...
Patel, Vidushi S, Cooper, Steven JB, Deakin, Janine E, Fulton, Bob, Graves, Tina, Warren, Wesley C, ...
Abstract Background Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin...
Origin and evolution of candidate mental retardation genes on the human X chromosome (MRX) (2008)
Delbridge, Margaret L, McMillan, Daniel A, Doherty, Ruth J, Deakin, Janine E, Graves, Jennifer
Abstract Background The human X chromosome has a biased gene content. One group of genes that is over-represented on the human X are those expressed in the brain, explaining the large number of...
Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes (2008)
Veyrunes, Frederic, Waters, P D., Miethke, Pat, Rens, Willem, McMillan, Daniel, Alsop, Amber E., ...
Copyright © 2008 by Cold Spring Harbor Laboratory Press
Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes (2008)
Veyrunes, Frederic, Waters, P D., Miethke, Pat, Rens, Willem, McMillan, Daniel, Alsop, Amber E., ...
Copyright © 2008 by Cold Spring Harbor Laboratory Press
Genome analysis of the platypus reveals unique signatures of evolution (2008)
Warren, Wesley C., Hillier, LaDeana W., Marshall Graves, Jennifer A., Birney, Ewan, Ponting, Chris P., Grützner, Frank, ...
We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a...
Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes (2008)
Veyrunes, Frédéric, Waters, Paul D., Miethke, Pat, Rens, Willem, McMillan, Daniel, Alsop, Amber E., ...
In therian mammals (placentals and marsupials), sex is determined by an XX female: XY male system, in which a gene (SRY) on the Y affects male determination. There is no equivalent in other amniotes,...
Defensins and the convergent evolution of platypus and reptile venom genes (2008)
Whittington, Camilla M., Papenfuss, Anthony T., Bansal, Paramjit, Torres, Allan M., Wong, Emily S.W., Deakin, Janine E., ...
When the platypus (Ornithorhynchus anatinus) was first discovered, it was thought to be a taxidermist’s hoax, as it has a blend of mammalian and reptilian features. It is a most remarkable mammal,...
Patel, Vidushi S., Cooper, Steven John Baynard, Deakin, Janine E., Fulton, Bob, Graves, Tina, Warren, Wesley, ...
Background: Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin locus, the...
Patel, Vidushi S., Cooper, Steven John Baynard, Deakin, Janine E., Fulton, Bob, Graves, Tina, Warren, Wesley, ...
Background: Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin locus, the...
Belov, Katherine, Sanderson, Claire E., Deakin, Janine E., Wong, Emily S.W., Assange, Daniel, McColl, Kaighin A., ...
The availability of the first marsupial genome sequence has allowed us to characterize the immunome of the gray short-tailed opossum (Monodelphis domestica). Here we report the identification of key...
El-Mogharbel, Nisrine, Wakefield, Matthew, Deakin, Janine E., Tsend-Ayush, Enkhjargal, Grutzner, Frank, Alsop, Amber E., ...
We isolated and characterized a cluster of platypus DMRT genes and compared their arrangement, location, and sequence across vertebrates. The DMRT gene cluster on human 9p24.3 harbors, in order,...
El-Mogharbel, Nisrine, Wakefield, Matthew, Deakin, Janine E., Tsend-Ayush, Enkhjargal, Grutzner, Frank, Alsop, Amber E., ...
We isolated and characterized a cluster of platypus DMRT genes and compared their arrangement, location, and sequence across vertebrates. The DMRT gene cluster on human 9p24.3 harbors, in order,...
Evolution and comparative analysis of the MHC Class III inflammatory region (2006)
Deakin, Janine E, Papenfuss, Anthony T, Belov, Katherine, Cross, Joseph GR, Coggill, Penny, Palmer, Sophie, ...
Abstract Background The Major Histocompatibility Complex (MHC) is essential for immune function. Historically, it has been subdivided into three regions (Class I, II, and III), but a cluster of...
Recent Assembly of an Imprinted Domain from Non-Imprinted Components (2006)
Robert W. Rapkins, Tim Hore, Megan Smithwick, Eleanor Ager, Andrew J. Pask, Marilyn B. Renfree, ...
Genomic imprinting, representing parent-specific expression of alleles at a locus, raises many questions about how—and especially why—epigenetic silencing of mammalian genes evolved. We present...
Katherine Belov, Janine E. Deakin, Anthony T. Papenfuss, Michelle L. Baker, Sandra D. Melman, Hannah V. Siddle, ...
Opossum genomic sequence data permit researchers to fill gaps in our knowledge of how the Major Histocompatibility Complex evolved within the mammalian lineage.
Katherine Belov, Janine E. Deakin, Anthony T. Papenfuss, Michelle L. Baker, Sandra D. Melman, Hannah V. Siddle, ...
The first sequenced marsupial genome promises to reveal unparalleled insights into mammalian evolution. We have used the Monodelphis domestica (gray short-tailed opossum) sequence to construct the...
Typescript. Bibliography: leaves 183-206.
Belov, Katherine, Deakin, Janine E, Papenfuss, Anthony T, Baker, Michelle L, Melman, Sandra D, Siddle, Hannah V, ...
The first sequenced marsupial genome promises to reveal unparalleled insights into mammalian evolution. We have used theMonodelphis domestica (gray short-tailed opossum) sequence to construct the...
Recent Assembly of an Imprinted Domain from Non-Imprinted Components
Rapkins, Robert W, Hore, Tim, Smithwick, Megan, Ager, Eleanor, Pask, Andrew J, Renfree, Marilyn B, ...
Genomic imprinting, representing parent-specific expression of alleles at a locus, raises many questions about how—and especially why—epigenetic silencing of mammalian genes evolved. We present...
Evolution and comparative analysis of the MHC Class III inflammatory region
Deakin, Janine E, Papenfuss, Anthony T, Belov, Katherine, Cross, Joseph GR, Coggill, Penny, Palmer, Sophie, ...
Belov, Katherine, Deakin, Janine E, Papenfuss, Anthony T, Baker, Michelle L, Melman, Sandra D, Siddle, Hannah V, ...
The first sequenced marsupial genome promises to reveal unparalleled insights into mammalian evolution. We have used theMonodelphis domestica (gray short-tailed opossum) sequence to construct the...
Recent Assembly of an Imprinted Domain from Non-Imprinted Components
Rapkins, Robert W, Hore, Tim, Smithwick, Megan, Ager, Eleanor, Pask, Andrew J, Renfree, Marilyn B, ...
Genomic imprinting, representing parent-specific expression of alleles at a locus, raises many questions about how—and especially why—epigenetic silencing of mammalian genes evolved. We present...
Evolution and comparative analysis of the MHC Class III inflammatory region
Deakin, Janine E, Papenfuss, Anthony T, Belov, Katherine, Cross, Joseph GR, Coggill, Penny, Palmer, Sophie, ...
A unique T cell receptor discovered in marsupials
Parra, Zuly E., Baker, Michelle L., Schwarz, Ryan S., Deakin, Janine E., Lindblad-Toh, Kerstin, Miller, Robert D.
T cells recognize antigens by using T cell receptors (TCRs) encoded by gene segments, called variable (V), diversity (D), and joining (J), that undergo somatic recombination to create diverse binding...
Belov, Katherine, Sanderson, Claire E., Deakin, Janine E., Wong, Emily S.W., Assange, Daniel, McColl, Kaighin A., ...
The availability of the first marsupial genome sequence has allowed us to characterize the immunome of the gray short-tailed opossum (Monodelphis domestica). Here we report the identification of key...
Origin and evolution of candidate mental retardation genes on the human X chromosome (MRX)
Delbridge, Margaret L, McMillan, Daniel A, Doherty, Ruth J, Deakin, Janine E, Graves, Jennifer A Marshall
The Status of Dosage Compensation in the Multiple X Chromosomes of the Platypus
Deakin, Janine E., Hore, Timothy A., Koina, Edda, Marshall Graves, Jennifer A.
Dosage compensation has been thought to be a ubiquitous property of sex chromosomes that are represented differently in males and females. The expression of most X-borne genes is equalized between XX...
The Evolution of Epigenetic Regulators CTCF and BORIS/CTCFL in Amniotes
Hore, Timothy A., Deakin, Janine E., Marshall Graves, Jennifer A.
CTCF is an essential, ubiquitously expressed DNA-binding protein responsible for insulator function, nuclear architecture, and transcriptional control within vertebrates. The gene CTCF was proposed...
Patel, Vidushi S, Cooper, Steven JB, Deakin, Janine E, Fulton, Bob, Graves, Tina, Warren, Wesley C, ...
Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes
Veyrunes, Frédéric, Waters, Paul D., Miethke, Pat, Rens, Willem, McMillan, Daniel, Alsop, Amber E., ...
Defensins and the convergent evolution of platypus and reptile venom genes
Whittington, Camilla M., Papenfuss, Anthony T., Bansal, Paramjit, Torres, Allan M., Wong, Emily S.W., Deakin, Janine E., ...
When the platypus (Ornithorhynchus anatinus) was first discovered, it was thought to be a taxidermist’s hoax, as it has a blend of mammalian and reptilian features. It is a most remarkable mammal,...