Jason E. Norton

Tiling Array Probes (2008)

Oligonucleotide Microarrays, Thomas J. Albert, Jason E. Norton, Michael N. Molla, Rebecca R. Selzer, Jaz Singh, ...

In this report we describe a rapid and cost effective comparative genomic strategy for mapping and identify single nucleotide polymorphisms, deletions and amplification across entire microbial...

Complete genome sequence of Treponema pallidumssp. pallidumstrain SS14 determined with oligonucleotide arrays (2008)

Matějková, Petra, Strouhal, Michal, Šmajs, David, Norris, Steven J, Palzkill, Timothy, Petrosino, Joseph F, ...

Abstract Background Syphilis spirochete Treponema pallidum ssp. pallidum remains the enigmatic pathogen, since no virulence factors have been identified and the pathogenesis of the disease is poorly...

Tracking the Evolution of the SARS Coronavirus Using High-Throughput, High-Density Resequencing Arrays (2004)

Wong, Christopher W., Albert, Thomas J., Vega, Vinsensius B., Norton, Jason E., Cutler, David J., Richmond, Todd A., ...

Mutations in the SARS-Coronavirus (SARS-CoV) can alter its clinical presentation, and the study of its mutation patterns in human populations can facilitate contact tracing. Here, we describe the...

Requirements for utilization of CREB binding protein by hypersensitive site two of the {beta}-globin locus control region (2002)

Johnson, Kirby D., Norton, Jason E., Bresnick, Emery H.

Strong transactivation of the &bgr;-globin genes is conferred by the &bgr;-globin locus control region (LCR), which consists of four erythroid-specific DNase I hypersensitive sites (HS1–HS4). HS2...

Requirements for utilization of CREB binding protein by hypersensitive site two of the β-globin locus control region

Johnson, Kirby D., Norton, Jason E., Bresnick, Emery H.

Strong transactivation of the β-globin genes is conferred by the β-globin locus control region (LCR), which consists of four erythroid-specific DNase I hypersensitive sites (HS1–HS4). HS2 has a...

Tracking the Evolution of the SARS Coronavirus Using High-Throughput, High-Density Resequencing Arrays

Wong, Christopher W., Albert, Thomas J., Vega, Vinsensius B., Norton, Jason E., Cutler, David J., Richmond, Todd A., ...

Mutations in the SARS-Coronavirus (SARS-CoV) can alter its clinical presentation, and the study of its mutation patterns in human populations can facilitate contact tracing. Here, we describe the...

Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis

Manjunatha, Ujjini H., Boshoff, Helena, Dowd, Cynthia S., Zhang, Liang, Albert, Thomas J., Norton, Jason E., ...

PA-824 is a promising new compound for the treatment of tuberculosis that is currently undergoing human trials. Like its progenitors metronidazole and CGI-17341, PA-824 is a prodrug of the...

Requirements for utilization of CREB binding protein by hypersensitive site two of the β-globin locus control region

Johnson, Kirby D., Norton, Jason E., Bresnick, Emery H.

Strong transactivation of the β-globin genes is conferred by the β-globin locus control region (LCR), which consists of four erythroid-specific DNase I hypersensitive sites (HS1–HS4). HS2 has a...

Tracking the Evolution of the SARS Coronavirus Using High-Throughput, High-Density Resequencing Arrays

Wong, Christopher W., Albert, Thomas J., Vega, Vinsensius B., Norton, Jason E., Cutler, David J., Richmond, Todd A., ...

Mutations in the SARS-Coronavirus (SARS-CoV) can alter its clinical presentation, and the study of its mutation patterns in human populations can facilitate contact tracing. Here, we describe the...

Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis

Manjunatha, Ujjini H., Boshoff, Helena, Dowd, Cynthia S., Zhang, Liang, Albert, Thomas J., Norton, Jason E., ...

PA-824 is a promising new compound for the treatment of tuberculosis that is currently undergoing human trials. Like its progenitors metronidazole and CGI-17341, PA-824 is a prodrug of the...