Jason Mark White

Enhanced Buprenorphine Analgesia with the Addition of Ultra-low-dose Naloxone in Healthy Subjects (2008)

La Vincente, Sophie F., White, Jason Mark, Somogyi, Andrew Alexander, Bochner, Felix, Chapleo, C B.

Animal studies have demonstrated that co-administration of an ultra-low-dose opioid antagonist with an opioid agonist may result in enhanced analgesia. Investigation of this effect in humans has been...

Inter- and intra-subject variability in ethanol pharmacokinetic parameters: Effects of testing interval and dose (2008)

Yelland, Lisa Nicole, Burns, Jaimi Paula, Sims, Noel, Salter, Amy Beatrix, White, Jason Mark

Calculation of a blood alcohol concentration (BAC) at the time of an offence by forward or back-extrapolation, using population average values for ethanol pharmacokinetic parameters or a single...

Enhanced Buprenorphine Analgesia with the Addition of Ultra-low-dose Naloxone in Healthy Subjects (2008)

La Vincente, Sophie F., White, Jason Mark, Somogyi, Andrew Alexander, Bochner, Felix, Chapleo, C B.

Animal studies have demonstrated that co-administration of an ultra-low-dose opioid antagonist with an opioid agonist may result in enhanced analgesia. Investigation of this effect in humans has been...

Antinociceptive effects of high dose remifentanil in male methadone-maintained patients (2008)

Hay, Justin Luke, White, Jason Mark, Bochner, Felix, Somogyi, Andrew Alexander

Copyright © 2008 European Federation of Chapters of the International Association for the Study of Pain Published by Elsevier Ltd.

Antinociceptive effects of high dose remifentanil in male methadone-maintained patients (2008)

Hay, Justin Luke, White, Jason Mark, Bochner, Felix, Somogyi, Andrew Alexander

Copyright © 2008 European Federation of Chapters of the International Association for the Study of Pain Published by Elsevier Ltd.

Pharmacotherapy of methamphetamine addiction: an update (2008)

Elkashef, Ahmed, Vocci, Frank, Hanson, Glen, White, Jason Mark, Wickes, Wendy, Tiihonen, Jari

Abstract Methamphetamine dependence is a serious public health problem worldwide for which there are no approved pharmacological treatments. Psychotherapy is still the mainstay of treatment; however,...

Pharmacotherapy of methamphetamine addiction: an update (2008)

Elkashef, Ahmed, Vocci, Frank, Hanson, Glen, White, Jason Mark, Wickes, Wendy, Tiihonen, Jari

Abstract Methamphetamine dependence is a serious public health problem worldwide for which there are no approved pharmacological treatments. Psychotherapy is still the mainstay of treatment; however,...

A cost-effectiveness analysis of heroin detoxification methods in the Australian National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD) (2006)

Shanahan, M. D., Doran, C. M., Digiusto, E., Bell, J., Lintzerisa, N., White, Jason Mark, ...

Abstract This economic evaluation was part of the Australian National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD) project. Data from four trials of heroin detoxification methods,...

Plasma drug concentrations and physiological measures in 'dance party' participants (2006)

Irvine, Rodney James, Keane, Michael, Felgate, P., McCann, U., Callaghan, P., White, Jason Mark

The increasing use of (7) 3,4-methylenedioxymethamphetamine (MDMA) in the setting of large dance parties (‘raves’) and clubs has been the source of some concern, because of potential acute...

Switching between methadone and morphine for maintenance treatment of opioid dependence: Impact on pain sensitivity and mood status (2006)

Mitchell, T. B., White, Jason Mark, Somogyi, Andrew Alexander, Bochner, Felix

This is an electronic version of an article published in American Journal on Addictions, 2006; 15 (4):311-315. American Journal on Addictions is available online at:...

A cost-effectiveness analysis of heroin detoxification methods in the Australian National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD) (2006)

Shanahan, M. D., Doran, C. M., Digiusto, E., Bell, J., Lintzerisa, N., White, Jason Mark, ...

Abstract This economic evaluation was part of the Australian National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD) project. Data from four trials of heroin detoxification methods,...

Plasma drug concentrations and physiological measures in 'dance party' participants (2006)

Irvine, Rodney James, Keane, Michael, Felgate, P., McCann, U., Callaghan, P., White, Jason Mark

The increasing use of (7) 3,4-methylenedioxymethamphetamine (MDMA) in the setting of large dance parties (‘raves’) and clubs has been the source of some concern, because of potential acute...

Switching between methadone and morphine for maintenance treatment of opioid dependence: Impact on pain sensitivity and mood status (2006)

Mitchell, T. B., White, Jason Mark, Somogyi, Andrew Alexander, Bochner, Felix

This is an electronic version of an article published in American Journal on Addictions, 2006; 15 (4):311-315. American Journal on Addictions is available online at:...

Pleasure into pain: the consequences of long-term opioid use (2004)

White, Jason Mark

One consequence of repeated drug administration is the development of adaptations in the nervous system, sometimes termed ‘drug-opposite’ responses. During administration, the effects of the drug...

Baclofen prevents MDMA-induced rise in core body temperature in rats (2004)

Bexis, S., Phillis, B. D., Ong, J., White, Jason Mark, Irvine, Rodney James

A number of deaths have been attributed to severe hyperthermia resulting from the ingestion of 3,4-methylenedioxymethamphetamine (MDMA). The mechanisms underlying these events are unclear. In an...

Evaluation of levo-alpha-acetylmethdol (LAAM) as an alternative treatment for methadone maintenance patients who regularly experience withdrawal: a pharmacokinetic and pharmacodynamic analysis (2004)

Newcombe, D. A.L., Bochner, Felix, White, Jason Mark, Somogyi, Andrew Alexander

The aim of this study was to determine if substitution of daily methadone with second daily levo-alpha-acetylmethadol (LAAM) would convert non-holders on methadone into holders on LAAM, and to...

Pleasure into pain: the consequences of long-term opioid use (2004)

White, Jason Mark

One consequence of repeated drug administration is the development of adaptations in the nervous system, sometimes termed ‘drug-opposite’ responses. During administration, the effects of the drug...

Baclofen prevents MDMA-induced rise in core body temperature in rats (2004)

Bexis, S., Phillis, B. D., Ong, J., White, Jason Mark, Irvine, Rodney James

A number of deaths have been attributed to severe hyperthermia resulting from the ingestion of 3,4-methylenedioxymethamphetamine (MDMA). The mechanisms underlying these events are unclear. In an...

Evaluation of levo-alpha-acetylmethdol (LAAM) as an alternative treatment for methadone maintenance patients who regularly experience withdrawal: a pharmacokinetic and pharmacodynamic analysis (2004)

Newcombe, D. A.L., Bochner, Felix, White, Jason Mark, Somogyi, Andrew Alexander

The aim of this study was to determine if substitution of daily methadone with second daily levo-alpha-acetylmethadol (LAAM) would convert non-holders on methadone into holders on LAAM, and to...

Opioid effects and opioid withdrawal during a 24 h dosing interval in patients maintained on buprenorphine (2003)

Lopatko, O. V., White, Jason Mark, Huber, A., Ling, W.

In maintenance patients methadone has been shown to produce considerable changes in opioid effects and withdrawal over the dosing interval. As a partial agonist buprenorphine may be expected to...

Buprenorphine versus methadone maintenance: a cost-effectiveness analysis (2003)

Doran, C. M., Shanahan, M., Mattick, R. P., Ali, Robert Leonard, White, Jason Mark, Bell, J.

This article presents the cost-effectiveness results of a randomised controlled trial conducted in two Australian cities. The trial was designed to assess the safety, efficacy and cost-effectiveness...

Comparative pharmacodynamics and pharmacokinetics of methadone and slow-release oral morphine for maintenance treatment of opioid dependence (2003)

Mitchell, T. B., White, Jason Mark, Somogyi, Andrew Alexander, Bochner, Felix

BACKGROUND: Slow-release oral morphine (SROM) has been proposed as an alternative maintenance pharmacotherapy to methadone for treatment of opioid dependence. However, the pharmacodynamics and...

Antagonist-precipitated heroin withdrawal under anaesthetic prior to maintenance naltrexone treatment: determinants of withdrawal severity (2003)

Ali, Robert Leonard, Thomas, P. D., White, Jason Mark, Gregor, C Mc, Danz, C. E.M., Gowing, L. R., ...

This study sought to characterize antagonist-precipitated heroin withdrawal during and immediately following anaesthesia and to identify the determinants of withdrawal severity and duration in 48...

In-patient benzodiazepine withdrawal: comparison of fixed and symptom-triggered taper methods (2003)

Gregor, C Mc, Machin, A., White, Jason Mark

This is an electronic version of an article published in Drug and Alcohol Review, 2003; 22 (2):175-180. Drug and Alcohol Review is available online at:...

Opioid effects and opioid withdrawal during a 24 h dosing interval in patients maintained on buprenorphine (2003)

Lopatko, O. V., White, Jason Mark, Huber, A., Ling, W.

In maintenance patients methadone has been shown to produce considerable changes in opioid effects and withdrawal over the dosing interval. As a partial agonist buprenorphine may be expected to...

Buprenorphine versus methadone maintenance: a cost-effectiveness analysis (2003)

Doran, C. M., Shanahan, M., Mattick, R. P., Ali, Robert Leonard, White, Jason Mark, Bell, J.

This article presents the cost-effectiveness results of a randomised controlled trial conducted in two Australian cities. The trial was designed to assess the safety, efficacy and cost-effectiveness...

Comparative pharmacodynamics and pharmacokinetics of methadone and slow-release oral morphine for maintenance treatment of opioid dependence (2003)

Mitchell, T. B., White, Jason Mark, Somogyi, Andrew Alexander, Bochner, Felix

BACKGROUND: Slow-release oral morphine (SROM) has been proposed as an alternative maintenance pharmacotherapy to methadone for treatment of opioid dependence. However, the pharmacodynamics and...

Antagonist-precipitated heroin withdrawal under anaesthetic prior to maintenance naltrexone treatment: determinants of withdrawal severity (2003)

Ali, Robert Leonard, Thomas, P. D., White, Jason Mark, Gregor, C Mc, Danz, C. E.M., Gowing, L. R., ...

This study sought to characterize antagonist-precipitated heroin withdrawal during and immediately following anaesthesia and to identify the determinants of withdrawal severity and duration in 48...

In-patient benzodiazepine withdrawal: comparison of fixed and symptom-triggered taper methods (2003)

Gregor, C Mc, Machin, A., White, Jason Mark

This is an electronic version of an article published in Drug and Alcohol Review, 2003; 22 (2):175-180. Drug and Alcohol Review is available online at:...

Which substitution pharmacotherapy is most effective in treating opioid dependence? (2002)

Gowing, Linda Rosemary, Ali, Robert Leonard, White, Jason Mark

The document attached has been archived with permission from the editor of the Medical Journal of Australia. An external link to the publisher’s copy is included.

Which substitution pharmacotherapy is most effective in treating opioid dependence? (2002)

Gowing, Linda Rosemary, Ali, Robert Leonard, White, Jason Mark

The document attached has been archived with permission from the editor of the Medical Journal of Australia. An external link to the publisher’s copy is included.

Attenuation of morphine withdrawal signs by the GABAB receptor agonist baclofen (2001)

Bexis, S., Ong, J., White, Jason Mark

Abstract The present study examined the effect of the γ-aminobutyric acidB (GABAB) receptor agonist, baclofen on naloxone-induced withdrawal signs in morphine-dependent rats and modification by the...

The acute effects of zolpidem compared to diazepam and lorazepam using radiotelemetry (2001)

Elliott, E. E., White, Jason Mark

The present study used a radiotelemetric method to compare the muscle relaxant, hypothermic and locomotor depressant actions of the imidazopyridine zolpidem, with those of the benzodiazepines...

Hyperalgesic responses in methadone maintenance patients (2001)

Doverty, Mark, White, Jason Mark, Somogyi, Andrew Alexander, Bochner, Felix, Ali, Robert Leonard, Ling, W.

Copyright © 2001 International Association for the Study of Pain. Published by Elsevier Science B.V.

Attenuation of morphine withdrawal signs by the GABAB receptor agonist baclofen (2001)

Bexis, S., Ong, J., White, Jason Mark

Abstract The present study examined the effect of the γ-aminobutyric acidB (GABAB) receptor agonist, baclofen on naloxone-induced withdrawal signs in morphine-dependent rats and modification by the...

The acute effects of zolpidem compared to diazepam and lorazepam using radiotelemetry (2001)

Elliott, E. E., White, Jason Mark

The present study used a radiotelemetric method to compare the muscle relaxant, hypothermic and locomotor depressant actions of the imidazopyridine zolpidem, with those of the benzodiazepines...

Hyperalgesic responses in methadone maintenance patients (2001)

Doverty, Mark, White, Jason Mark, Somogyi, Andrew Alexander, Bochner, Felix, Ali, Robert Leonard, Ling, W.

Copyright © 2001 International Association for the Study of Pain. Published by Elsevier Science B.V.