Prieto, Jesús, Redondo, Pilar, Padró, Daniel, Arnould, Sylvain, Epinat, Jean-Charles, Pâques, Frédéric, ...
Meganucleases are sequence-specific endonucleases with large cleavage sites that can be used to induce efficient homologous gene targeting in cultured cells and plants. These enzymes open novel...
Chames, Patrick, Epinat, Jean-Charles, Guillier, Sophie, Patin, Amélie, Lacroix, Emmanuel, Pâques, Frédéric
Homing endonucleases, endonucleases capable of recognizing long DNA sequences, have been shown to be a tool of choice for precise and efficient genome engineering. Consequently, the possibility to...
A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells (2003)
Epinat, Jean-Charles, Arnould, Sylvain, Chames, Patrick, Rochaix, Pascal, Desfontaines, Dominique, Puzin, Clémence, ...
Homologous gene targeting is the ultimate tool for reverse genetics, but its use is often limited by low efficiency. In a number of recent studies, site‐ specific DNA double‐strand breaks...
A revised annotation and comparative analysis of Helicobacter pylori genomes
Boneca, Ivo G., Reuse, Hilde De, Epinat, Jean-Charles, Pupin, Maude, Labigne, Agnès, Moszer, Ivan
Huge amounts of genomic information are currently being generated. Therefore, biologists require structured, exhaustive and comparative databases. The PyloriGene database...
A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells
Epinat, Jean-Charles, Arnould, Sylvain, Chames, Patrick, Rochaix, Pascal, Desfontaines, Dominique, Puzin, Clémence, ...
Homologous gene targeting is the ultimate tool for reverse genetics, but its use is often limited by low efficiency. In a number of recent studies, site- specific DNA double-strand breaks (DSBs) have...
Chames, Patrick, Epinat, Jean-Charles, Guillier, Sophie, Patin, Amélie, Lacroix, Emmanuel, Pâques, Frédéric
Homing endonucleases, endonucleases capable of recognizing long DNA sequences, have been shown to be a tool of choice for precise and efficient genome engineering. Consequently, the possibility to...
A revised annotation and comparative analysis of Helicobacter pylori genomes
Boneca, Ivo G., Reuse, Hilde De, Epinat, Jean-Charles, Pupin, Maude, Labigne, Agnès, Moszer, Ivan
Huge amounts of genomic information are currently being generated. Therefore, biologists require structured, exhaustive and comparative databases. The PyloriGene database...
A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells
Epinat, Jean-Charles, Arnould, Sylvain, Chames, Patrick, Rochaix, Pascal, Desfontaines, Dominique, Puzin, Clémence, ...
Homologous gene targeting is the ultimate tool for reverse genetics, but its use is often limited by low efficiency. In a number of recent studies, site- specific DNA double-strand breaks (DSBs) have...
Chames, Patrick, Epinat, Jean-Charles, Guillier, Sophie, Patin, Amélie, Lacroix, Emmanuel, Pâques, Frédéric
Homing endonucleases, endonucleases capable of recognizing long DNA sequences, have been shown to be a tool of choice for precise and efficient genome engineering. Consequently, the possibility to...
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences
Smith, Julianne, Grizot, Sylvestre, Arnould, Sylvain, Duclert, Aymeric, Epinat, Jean-Charles, Chames, Patrick, ...
Meganucleases, or homing endonucleases (HEs) are sequence-specific endonucleases with large (>14 bp) cleavage sites that can be used to induce efficient homologous gene targeting in cultured cells...
Prieto, Jesús, Redondo, Pilar, Padró, Daniel, Arnould, Sylvain, Epinat, Jean-Charles, Pâques, Frédéric, ...
Meganucleases are sequence-specific endonucleases with large cleavage sites that can be used to induce efficient homologous gene targeting in cultured cells and plants. These enzymes open novel...