c-Abl Phosphorylates Hdmx and Regulates Its Interaction with p53 (2009)
Zuckerman, Valentina, Lenos, Kristiaan, Popowicz, Grzegorz M., Silberman, Isabelle, Grossman, Tamar, Marine, Jean-Christophe, ...
Nyabi, Omar, Naessens, Michaël, Haigh, Katharina, Gembarska, Agnieszka, Goossens, Steven, Maetens, Marion, ...
The ability to rapidly and efficiently generate reliable Cre/loxP conditional transgenic mice would greatly complement global high-throughput gene targeting initiatives aimed at identifying gene...
Galluzzi, L, Aaronson, SA, Abrams, J, Alnemri, ES, Andrews, DW, Baehrecke, EH, ...
Cell death is essential for a plethora of physiological processes, and its deregulation characterizes numerous human diseases. Thus, the in-depth investigation of cell death and its mechanisms...
Marine, Jean-Christophe, Berx, Geert
How and when a tumor acquires metastatic properties remain largely unknown. Recent work has uncovered an intricate new mechanism through which transforming growth factor-beta (TGFβ) acts in concert...
Real-time qPCR as a tool for evaluating RNAi-mediated gene silencing (2008)
Van Maerken, Tom, Mestdagh, Pieter, De Clercq, Sarah, Pattyn, Filip, Yigit, Nurten, De Paepe, Anne, ...
This article describes how rt-qPCR can be implemented as a tool to monitor silencing efficiency and functional effects of RNA interference (RNAi)-mediated gene knockdown, using examples from our...
Pendeville-Samain, Hélène, Carpino, Nick, Marine, Jean-Christophe, Takahashi, Yukata, Muller, Marc, Martial, Joseph, ...
Overexpression and inhibitor studies have suggested that the c-Myc target gene for ornithine decarboxylase (ODC), the enzyme which converts ornithine to putrescine, plays an important role in diverse...