Jean-François Hocquette

Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets (2009)

Chelh, Ilham, Meunier, Bruno, Picard, Brigitte, Reecy, Mark, Chevalier, Catherine, Hocquette, Jean-François, ...

Abstract Background Myostatin (MSTN), a member of the TGF-β superfamily, has been identified as a negative regulator of skeletal muscle mass. Inactivating mutations in the MSTN gene are responsible...

Image Analysis and Data Normalization Procedures are Crucial for Microarray Analyses (2008)

Ali Kpatcha Kadanga, Christine Leroux, Muriel Bonnet, Stéphanie Chauvet, Bruno Meunier, Isabelle Cassar-Malek, ...

This study was conducted with the aim of optimizing the experimental design of array experiments. We compared two image analysis and normalization procedures prior to data analysis using two...

Target genes of myostatin loss-of-function in muscles of late bovine fetuses (2007)

Cassar-Malek, Isabelle, Passelaigue, Florent, Bernard, Carine, Léger, Jean, Hocquette, Jean-François

Abstract Background Myostatin, a muscle-specific member of the Transforming Growth Factor beta family, negatively regulates muscle development. Double-muscled (DM) cattle have a loss-of-function...

Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis. (2007)

Fergani, Anissa, Oudart, Hugues, Gonzalez De Aguilar, Jose-Luis, Fricker, Bastien, René, Frédérique, Hocquette, Jean-François, ...

Amyotrophic lateral sclerosis (ALS) is the most common adult motor neuron disease, causing motor neuron degeneration, muscle atrophy, paralysis, and death. Despite this degenerative process, a stable...

Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis. (2007)

Fergani, Anissa, Oudart, Hugues, Gonzalez De Aguilar, Jose-Luis, Fricker, Bastien, René, Frédérique, Hocquette, Jean-François, ...

Amyotrophic lateral sclerosis (ALS) is the most common adult motor neuron disease, causing motor neuron degeneration, muscle atrophy, paralysis, and death. Despite this degenerative process, a stable...

Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis. (2007)

Fergani, Anissa, Oudart, Hugues, Gonzalez De Aguilar, Jose-Luis, Fricker, Bastien, René, Frédérique, Hocquette, Jean-François, ...

Amyotrophic lateral sclerosis (ALS) is the most common adult motor neuron disease, causing motor neuron degeneration, muscle atrophy, paralysis, and death. Despite this degenerative process, a stable...

Performance, slaughter characteristics and meat quality of young bulls from Belgian Blue, Limousin and Aberdeen Angus breeds fattened with a sugar-beet pulp or a cereal-based diet (2006)

Cuvelier, Christine, Cabaraux, Jean-François, Dufrasne, Isabelle, Clinquart, Antoine, Hocquette, Jean-François, Istasse, Louis, ...

Thirty-six young fattening bulls from three breeds (Belgian Blue, Limousin and Aberdeen Angus) were fattened over 5 months with fattening diets based either on sugar-beet pulp or on cereals....

Comparison of composition and quality traits of meat from young finishing bulls from Belgian Blue, Limousin and Aberdeen Angus breeds (2006)

Cuvelier, Christine, Clinquart, Antoine, Hocquette, Jean-François, Cabaraux, Jean-François, Dufrasne, Isabelle, Istasse, Louis, ...

Thirty-six young finishing bulls from three breeds (Belgian Blue, Limousin and Aberdeen Angus) were fattened over five months with finishing diets based either on sugar-beet pulp or on cereals....

Unusual metabolic characteristics in skeletal muscles of transgenic rabbits for human lipoprotein lipase (2004)

Gondret, Florence, Jadhao, Sanjay B, Damon, Marie, Herpin, Patrick, Viglietta, Céline, Houdebine, Louis-Marie, ...

Abstract Background The lipoprotein lipase (LPL) hydrolyses circulating triacylglycerol-rich lipoproteins. Thereby, LPL acts as a metabolic gate-keeper for fatty acids partitioning between adipose...

Transcriptome Analysis of Two Bovine Muscles during Ontogenesis (2003)

Sudre, Karine, Leroux, Christine, Piétu, Geneviève, Cassar-Malek, Isabelle, Petit, Elisabeth, Listrat, Anne, ...

Macro-arrays, on which 1339 human skeletal muscle cDNA clone inserts had been spotted as PCR products, were used to make large-scale measurement of gene expression in bovine muscles during...

Image Analysis and Data Normalization Procedures are Crucial for Microarray Analyses

Kadanga, Ali Kpatcha, Leroux, Christine, Bonnet, Muriel, Chauvet, Stéphanie, Meunier, Bruno, Cassar-Malek, Isabelle, ...

This study was conducted with the aim of optimizing the experimental design of array experiments. We compared two image analysis and normalization procedures prior to data analysis using two...