Jean-Loup Bascands

Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy. (2009)

Klein, J., Gonzalez, J., Duchene, J., Esposito, L., Pradère, Jean-Philippe, Neau, Eric, ...

Renal fibrosis is the common histological feature of advanced glomerular and tubulointerstitial disease leading to end-stage renal disease (ESRD). However, specific antifibrotic therapies to slow...

Lysophosphatidic acid and renal fibrosis. (2008)

Pradère, Jean-Philippe, Gonzalez, Julien, Klein, Julie, Valet, Philippe, Grès, Sandra, Salant, David, ...

The development of fibrosis involves a multitude of events and molecules. Until now the majority of these molecules were found to be proteins or peptides. But recent data show significant involvement...

Lysophosphatidic acid and renal fibrosis. (2008)

Pradère, Jean-Philippe, Gonzalez, Julien, Klein, Julie, Valet, Philippe, Grès, Sandra, Salant, David, ...

The development of fibrosis involves a multitude of events and molecules. Until now the majority of these molecules were found to be proteins or peptides. But recent data show significant involvement...

Urine in clinical proteomics. (2008)

Decramer, Stéphane, Gonzalez De Peredo, Anne, Breuil, Benjamin, Mischak, Harald, Monsarrat, Bernard, Bascands, Jean-Loup, ...

Urine has become one of the most attractive biofluids in clinical proteomics as it can be obtained non-invasively in large quantities and is stable compared with other biofluids. The urinary proteome...

Urine in clinical proteomics. (2008)

Decramer, Stéphane, Gonzalez De Peredo, Anne, Breuil, Benjamin, Mischak, Harald, Monsarrat, Bernard, Bascands, Jean-Loup, ...

Urine has become one of the most attractive biofluids in clinical proteomics as it can be obtained non-invasively in large quantities and is stable compared with other biofluids. The urinary proteome...

Urine in clinical proteomics. (2008)

Decramer, Stéphane, Gonzalez De Peredo, Anne, Breuil, Benjamin, Mischak, Harald, Monsarrat, Bernard, Bascands, Jean-Loup, ...

Urine has become one of the most attractive biofluids in clinical proteomics as it can be obtained non-invasively in large quantities and is stable compared with other biofluids. The urinary proteome...

Lysophosphatidic acid and renal fibrosis. (2008)

Pradère, Jean-Philippe, Gonzalez, Julien, Klein, Julie, Valet, Philippe, Grès, Sandra, Salant, David, ...

The development of fibrosis involves a multitude of events and molecules. Until now the majority of these molecules were found to be proteins or peptides. But recent data show significant involvement...

Obstructive nephropathy: insights from genetically engineered animals. (2005)

Bascands, Jean-Loup, Schanstra, Joost

Congenital obstructive nephropathy is the primary cause for end-stage renal disease (ESRD) in children. An increasingly used animal model of obstructive nephropathy is unilateral ureteral obstruction...

Obstructive nephropathy: insights from genetically engineered animals. (2005)

Bascands, Jean-Loup, Schanstra, Joost

Congenital obstructive nephropathy is the primary cause for end-stage renal disease (ESRD) in children. An increasingly used animal model of obstructive nephropathy is unilateral ureteral obstruction...

Obstructive nephropathy: insights from genetically engineered animals. (2005)

Bascands, Jean-Loup, Schanstra, Joost

Congenital obstructive nephropathy is the primary cause for end-stage renal disease (ESRD) in children. An increasingly used animal model of obstructive nephropathy is unilateral ureteral obstruction...

The bradykinin B1 receptor contributes to the cardioprotective effects of AT1 blockade after experimental myocardial infarction (2004)

Tschöpe, Carsten, Spillmann, Frank, Altmann, Christine, Koch, Matthias, Westermann, Dirk, Dhayat, Nasser, ...

Objective: To investigate the role of the bradykinin B1 receptor (B1R) on the angiotensin receptor AT1 blockade-dependent cardioprotective effects, we studied the B1R regulation in wild-type rats...

In vivo bradykinin B2 receptor activation reduces renal fibrosis

Schanstra, Joost P., Neau, Eric, Drogoz, Pascale, Arevalo Gomez, Miguel A., Lopez Novoa, José Miguel, Calise, Denis, ...

Angiotensin-converting enzyme (ACE) inhibitors reduce the progression of various fibrotic renal diseases both in humans and in animal models. Unilateral ureteral obstruction (UUO) is an animal model...

In vivo bradykinin B2 receptor activation reduces renal fibrosis

Schanstra, Joost P., Neau, Eric, Drogoz, Pascale, Arevalo Gomez, Miguel A., Lopez Novoa, José Miguel, Calise, Denis, ...

Angiotensin-converting enzyme (ACE) inhibitors reduce the progression of various fibrotic renal diseases both in humans and in animal models. Unilateral ureteral obstruction (UUO) is an animal model...

Cyclosporine A-induced increase in glomerular cyclic GMP in rats and the involvement of the endothelinB receptor

Tack, Ivan, Marin-Castano, Encarna, Bascands, Jean-Loup, Pecher, Christiane, Ader, Jean-Louis, Girolami, Jean-Pierre

A transient two fold increase in the cyclic GMP content was observed in rat freshly isolated glomeruli 6 to 9 h after a single subcutaneous injection of 20 mg kg−1 cyclosporine A (CsA) in...