Translocation of bacterial NOD2 agonist and its link with inflammation (2009)
Kim, Oh, Monsel, Antoine, Bertrand, Michèle, Cavaillon, Jean-Marc, Coriat, Pierre, Adib-Conquy, Minou
Abstract Introduction The gut is often considered as the motor of critical illness through bacterial translocation, which amplifies the inflammatory response and alters the immune status. However,...
Monocyte TREM-1 membrane expression in non-infectious inflammation (2009)
Abstract Sterile or non-infectious inflammation and severe infection are accompanied by very similar events. Damage (or danger)-associated molecular patterns and pathogen-associated molecular...
Biofilm forming P. aeruginosainduces an enhanced inflammatory response in human monocytes (2007)
Ciornei, Cristina, Beloin, Christophe, Novikov, Alexey, Caroff, Martine, Fitting, Catherine, Ghigo, Jean-Marc, ...
No abstract available.
Bench-to-bedside review: Endotoxin tolerance as a model of leukocyte reprogramming in sepsis (2006)
Cavaillon, Jean-Marc, Adib-Conquy, Minou
Abstract Endotoxin tolerance is defined as a reduced responsiveness to a lipopolysaccharide (LPS) challenge following a first encounter with endotoxin. Endotoxin tolerance protects against a lethal...
Cloëz-Tayarani, Isabelle, Petit-Bertron, Anne-France, Venters, Homer D., Cavaillon, Jean-Marc
In order to provide additional insight into the in vivo significance of serotonin [5‐hydroxytryptamine (5‐HT)] in inflammation, we examined its effect on the production of tumor...
Rayhane, Naïma, Fitting, Catherine, Lortholary, Olivier, Dromer, Francoise, Cavaillon, Jean-Marc
Lipopolysaccharide (LPS) pretreatment of mice resulted in a significantly enhanced survival after disseminated Cryptococcus neoformans infection. The survival was associated with reduced fungal...
Müller-Alouf, Heide, Proft, Thomas, Zollner, Thomas M., Gerlach, Dieter, Champagne, Eric, Desreumaux, Pierre, ...
Streptococcal mitogenic exotoxin Z (SMEZ), a superantigen derived from Streptococcus pyogenes, provoked expansion of human lymphocytes expressing the Vβ 2, 4, 7 and 8 motifs of T-cell receptor. SMEZ...
Bassinet, Laurence, Fitting, Catherine, Housset, Bruno, Cavaillon, Jean-Marc, Guiso, Nicole
After interaction with tracheal epithelial cells, Bordetella pertussis induces the secretion of interleukin-6. This secretion is dependent on the expression of adenylate cyclase-hemolysin by the...
Rayhane, Naïma, Fitting, Catherine, Lortholary, Olivier, Dromer, Francoise, Cavaillon, Jean-Marc
Lipopolysaccharide (LPS) pretreatment of mice resulted in a significantly enhanced survival after disseminated Cryptococcus neoformans infection. The survival was associated with reduced fungal...
Müller-Alouf, Heide, Proft, Thomas, Zollner, Thomas M., Gerlach, Dieter, Champagne, Eric, Desreumaux, Pierre, ...
Streptococcal mitogenic exotoxin Z (SMEZ), a superantigen derived from Streptococcus pyogenes, provoked expansion of human lymphocytes expressing the Vβ 2, 4, 7 and 8 motifs of T-cell receptor. SMEZ...
Bassinet, Laurence, Fitting, Catherine, Housset, Bruno, Cavaillon, Jean-Marc, Guiso, Nicole
After interaction with tracheal epithelial cells, Bordetella pertussis induces the secretion of interleukin-6. This secretion is dependent on the expression of adenylate cyclase-hemolysin by the...
Bench-to-bedside review: Endotoxin tolerance as a model of leukocyte reprogramming in sepsis
Cavaillon, Jean-Marc, Adib-Conquy, Minou
Endotoxin tolerance is defined as a reduced responsiveness to a lipopolysaccharide (LPS) challenge following a first encounter with endotoxin. Endotoxin tolerance protects against a lethal challenge...
Kapetanovic, Ronan, Nahori, Marie-Anne, Balloy, Viviane, Fitting, Catherine, Philpott, Dana J., Cavaillon, Jean-Marc, ...
Toll-like receptors (TLRs) are involved in the sensing of microbially derived compounds. We analyzed the contribution of these receptors to cytokine production by macrophages following stimulation...
Simple Method for Repurification of Endotoxins for Biological Use▿
Tirsoaga, Alina, Novikov, Alexey, Adib-Conquy, Minou, Werts, Catherine, Fitting, Catherine, Cavaillon, Jean-Marc, ...
A method for obtaining highly purified endotoxin (lipopolysaccharide [LPS]) in a few hours by repurification of commercial or laboratory preparations was devised. It avoids the use of phenol, which...
Geny, Blandine, Khun, Huot, Fitting, Catherine, Zarantonelli, Leticia, Mazuet, Christelle, Cayet, Nadège, ...
When intraperitoneally injected into Swiss mice, Clostridium sordellii lethal toxin reproduces the fatal toxic shock syndrome observed in humans and animals after natural infection. This animal model...
Neutrophils in Cystic Fibrosis Display a Distinct Gene Expression Pattern
Adib-Conquy, Minou, Pedron, Thierry, Petit-Bertron, Anne-France, Tabary, Olivier, Corvol, Harriet, Jacquot, Jacky, ...
We compared gene expression in blood neutrophils (polymorphonuclear leukocytes, or PMNs) collected from healthy subjects with those of cystic fibrosis (CF) patients devoid of bacterial colonization....
Monocyte TREM-1 membrane expression in non-infectious inflammation
Sterile or non-infectious inflammation and severe infection are accompanied by very similar events. Damage (or danger)-associated molecular patterns and pathogen-associated molecular patterns trigger...