Jean-Paul Couetil

Extracellular matrix remodelling in human aortic valve disease: the role of matrix metalloproteinases and their tissue inhibitors (2005)

Fondard, Olivier, Detaint, Delphine, Iung, Bernard, Choqueux, Christine, Adle-Biassette, Homa, Jarraya, Mohamed, ...

Aims Aortic valve diseases are characterized by pathological remodelling of valvular tissue but the cellular and molecular effectors involved in these processes are not well known. The role of matrix...

Extracellular matrix remodelling in human aortic valve disease: the role of matrix metalloproteinases and their tissue inhibitors (2005)

Fondard, Olivier, Detaint, Delphine, Iung, Bernard, Choqueux, Christine, Adle-Biassette, Homa, Jarraya, Mohamed, ...

Aims Aortic valve diseases are characterized by pathological remodelling of valvular tissue but the cellular and molecular effectors involved in these processes are not well known. The role of matrix...

TNF-α, inefficient by itself, potentiates IL-1β-induced PGHS-2 expression in human pulmonary microvascular endothelial cells: requirement of NF-κB and p38 MAPK pathways

Said, Fatima Ait, Werts, Catherine, Elalamy, Ismaïl, Couetil, Jean-Paul, Jacquemin, Claude, Hatmi, Mohamed

Prostaglandin H synthase-2 (PGHS-2), is an inducible enzyme involved in various inflammatory responses. We established here that interleukin-1β (IL-1β) but not tumour necrosis factor-α (TNF-α)...