Scientific Commons: Jean-Paul Thiery

Evaluation of methods for amplification of picogram amounts of total RNA for whole genome expression profiling (2009)

Clément-Ziza, Mathieu, Gentien, David, Lyonnet, Stanislas, Thiery, Jean-Paul, Besmond, Claude, Decraene, Charles

Abstract Background For more than a decade, microarrays have been a powerful and widely used tool to explore the transcriptome of biological systems. However, the amount of biological material from...

BIOINFORMATICS ORIGINAL PAPER (2008)

Gene Expression, Karen Willbr, Francois Radvanyi, Jean-pierre Nadal, Jean-paul Thiery

Identifying genes from up–down properties of microarray expression series Vol. 21 no. 20 2005, pages 3859–3864 doi:10.1093/bioinformatics/bti549

† Author for correspondence (2008)

Michael A. Matthay, Jean-paul Thiery, Frank Lafont, Martha F. Stampfer, Brigitte Boyer

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Frequent PTENgenomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells (2008)

Marty, Bérengère, Maire, Virginie, Gravier, Eléonore, Rigaill, Guillem, Vincent-Salomon, Anne, Kappler, Marion, ...

Abstract Introduction Basal-like carcinomas (BLCs) and human epidermal growth factor receptor 2 overexpressing (HER2+) carcinomas are the subgroups of breast cancers that have the most aggressive...

Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells. (2008)

Taddei, Ilaria, Deugnier, Marie-Ange, Faraldo, Marisa, Petit, Valérie, Bouvard, Daniel, Medina, Daniel, ...

The mammary gland epithelium comprises two major cell types: basal and luminal. Basal cells interact directly with the extracellular matrix (ECM) and express higher levels of the ECM receptors,...

Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells. (2008)

Taddei, Ilaria, Deugnier, Marie-Ange, Faraldo, Marisa, Petit, Valérie, Bouvard, Daniel, Medina, Daniel, ...

The mammary gland epithelium comprises two major cell types: basal and luminal. Basal cells interact directly with the extracellular matrix (ECM) and express higher levels of the ECM receptors,...

Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells. (2008)

Taddei, Ilaria, Deugnier, Marie-Ange, Faraldo, Marisa, Petit, Valérie, Bouvard, Daniel, Medina, Daniel, ...

The mammary gland epithelium comprises two major cell types: basal and luminal. Basal cells interact directly with the extracellular matrix (ECM) and express higher levels of the ECM receptors,...

High-Resolution Mapping of DNA Breakpoints to Define True Recurrences Among Ipsilateral Breast Cancers (2008)

Bollet, Marc A., Servant, Nicolas, Neuvial, Pierre, Decraene, Charles, Lebigot, Ingrid, Meyniel, Jean-Philippe, ...

Background To distinguish new primary breast cancers from true recurrences, pangenomic analyses of DNA copy number alterations (CNAs) using single-nucleotide polymorphism arrays have proven useful. ...

Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: contribution of exogenous versus endogenous carcinogens (2005)

Wallerand, Hervé, Bakkar, Ashraf A., Pairon, Jean-Claude, Yang, Yu-Ching, Vordos, Dimitri, ...

Smoking is a major risk factor for urothelial cell carcinoma of the bladder (UCC). Mutations in the FGFR3 and TP53 genes have been shown to define two distinct pathways in superficial papillary and...

Identifying genes from up-down properties of microarray expression series (2005)

Willbrand, Karen, Radvanyi, Francois, Nadal, Jean-Pierre, Thiery, Jean-Paul, Fink, Thomas M. A.

Motivation: We consider any collection of microarrays that can be ordered to form a progression; for example, as a function of time, severity of disease or dose of a stimulant. By plotting the...

Enrichment methods to detect bone marrow micrometastases in breast carcinoma patients: clinical relevance (2004)

Choesmel, Valérie, Pierga, Jean-Yves, Nos, Claude, Vincent-Salomon, Anne, Sigal-Zafrani, Brigitte, Thiery, Jean-Paul, ...

Abstract Introduction Improving technologies for the detection and purification of bone marrow (BM) micrometastatic cells in breast cancer patients should lead to earlier prognosis of the risk of...

Analysis of array CGH data: from signal ratio to gain and loss of DNA regions (2004)

Hupé, Philippe, Stransky, Nicolas, Thiery, Jean-Paul, Radvanyi, François, Barillot, Emmanuel