Jeffery L. Keene

Intratracheal administration of endotoxin and cytokines: VIII. LPS induces E-selectin expression; anti-E-selectin and soluble E-selectin inhibit acute inflammation (1994)

Collins, Tucker, Yi, Eunhee S., Guo, Kaizhi, Williams, James H., Steininger, Christina N., Welply, Joseph K., ...

E-selectin is an inducible endothelial adhesion molecule that binds neutrophils. E-selectin mRNA is not constitutively detectable in the lungs of rats. Intratracheal injection of LPS induces...

Minute dosages of ανβ3-targeted fumagillin nanoparticles impair Vx-2 tumor angiogenesis and development in rabbits

Winter, Patrick M., Schmieder, Anne H., Caruthers, Shelton D., Keene, Jeffery L., Zhang, Huiying, Wickline, Samuel A., ...

Fumagillin suppresses angiogenesis in cancer models and clinical trials, but it is associated with neurotoxicity at systemic doses. In this study, ανβ3-targeted fumagillin nanoparticles were used...