Enhancement of Gene Delivery to Cancer Cells by a Retargeted Adenovirus (2008)
Oh, Kwang Seok, Engler, Jeffrey A., Joung, In Sil
The inefficiency of in vivo gene transfer using currently available vectors reflects a major hurdle in cancer gene therapy. Both viral and non-viral approaches that improve gene transfer efficiency...
Steele, Darin L., El-Kabbani, O., Dunten, P., Windsor, L.Jack, Kammlott, R.Ursula, Crowther, R.L., ...
Human stromelysin-1 is a member of the matrix metalloproteinase (MMP) family of enzymes. The active site glutamic acid of the MMPs is conserved throughout the family and plays a pivotal role in the...
Angeletti, Peter C., Engler, Jeffrey A.
Adenovirus (Ad) replicative complexes form at discrete sites on the nuclear matrix (NM) via an interaction mediated by the precursor of the terminal protein (pTP). The identities of cellular proteins...
Angeletti, Peter C., Engler, Jeffrey A.
Adenovirus (Ad) replicative complexes form at discrete sites on the nuclear matrix (NM) through the interaction of Ad preterminal protein (pTP). The NM is a highly salt-resistant fibrillar network...
Kwoh, T.Jesse, Engler, Jeffrey A.
The entire DNA nucleotide sequence of a 3.0 kilobase pair Hind I I I fragment containing the chicken cytoplasmic thymldine kinase gene was determined. Ollgonucleotide linker insertion mutations...
Thesis - Wisconsin.
Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation
Borhani, David W., Rogers, Danise P., Engler, Jeffrey A., Brouillette, Christie G.
The structure of truncated human apolipoprotein A-I (apo A-I), the major protein component of high density lipoprotein, has been determined at 4-Å resolution. The crystals comprise residues...
Human Papillomavirus DNA Replication Compartments in a Transient DNA Replication System
Swindle, C. Scott, Zou, Nianxiang, Van Tine, Brian A., Shaw, George M., Engler, Jeffrey A., Chow, Louise T.
Many DNA viruses replicate their genomes at nuclear foci in infected cells. Using indirect immunofluorescence in combination with fluorescence in situ hybridization, we colocalized the human...
Association of the Human Papillomavirus Type 11 E1 Protein with Histone H1
Swindle, C. Scott, Engler, Jeffrey A.
The E1 and E2 proteins are the only virus-encoded factors required for human papillomavirus (HPV) DNA replication. The E1 protein is a DNA helicase responsible for initiation of DNA replication at...
Angeletti, Peter C., Engler, Jeffrey A.
Adenovirus (Ad) replicative complexes form at discrete sites on the nuclear matrix (NM) via an interaction mediated by the precursor of the terminal protein (pTP). The identities of cellular proteins...
Conserved Sequences at the Origin of Adenovirus DNA Replication
Stillman, Bruce W., Topp, William C., Engler, Jeffrey A.
The origin of adenovirus DNA replication lies within an inverted sequence repetition at either end of the linear, double-stranded viral DNA. Initiation of DNA replication is primed by a...
Increase of GKLF/KLF-4 mRNA and protein expression during progression of breast cancer1
Foster, K. Wade, Frost, Andra R., McKie-Bell, Peggy, Lin, Chin-Yu, Engler, Jeffrey A., Grizzle, William E., ...
Genetic alterations found in carcinomas can alter specific regulatory pathways and provide a selective growth advantage by activation of transforming oncogenes. A subset of these genes, including...
Nuclear localization of KLF4 is associated with an aggressive phenotype in early stage breast cancer
Pandya, Ashka, Talley, Lynya I., Frost, Andra R., Fitzgerald, Thomas J., Trivedi, Vivek, Chakravarthy, Mithun, ...
Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation
Borhani, David W., Rogers, Danise P., Engler, Jeffrey A., Brouillette, Christie G.
The structure of truncated human apolipoprotein A-I (apo A-I), the major protein component of high density lipoprotein, has been determined at 4-Å resolution. The crystals comprise residues...
Human Papillomavirus DNA Replication Compartments in a Transient DNA Replication System
Swindle, C. Scott, Zou, Nianxiang, Van Tine, Brian A., Shaw, George M., Engler, Jeffrey A., Chow, Louise T.
Many DNA viruses replicate their genomes at nuclear foci in infected cells. Using indirect immunofluorescence in combination with fluorescence in situ hybridization, we colocalized the human...
Association of the Human Papillomavirus Type 11 E1 Protein with Histone H1
Swindle, C. Scott, Engler, Jeffrey A.
The E1 and E2 proteins are the only virus-encoded factors required for human papillomavirus (HPV) DNA replication. The E1 protein is a DNA helicase responsible for initiation of DNA replication at...
Angeletti, Peter C., Engler, Jeffrey A.
Adenovirus (Ad) replicative complexes form at discrete sites on the nuclear matrix (NM) via an interaction mediated by the precursor of the terminal protein (pTP). The identities of cellular proteins...
Conserved Sequences at the Origin of Adenovirus DNA Replication
Stillman, Bruce W., Topp, William C., Engler, Jeffrey A.
The origin of adenovirus DNA replication lies within an inverted sequence repetition at either end of the linear, double-stranded viral DNA. Initiation of DNA replication is primed by a...