Reduced-representation methylation mapping (2008)
Jeddeloh, Jeffrey A, Greally, John M, Rando, Oliver J
Abstract The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA...
Comprehensive high-throughput arrays for relative methylation (CHARM) (2008)
Irizarry, Rafael A., Ladd-Acosta, Christine, Carvalho, Benilton, Wu, Hao, Brandenburg, Sheri A., Jeddeloh, Jeffrey A., ...
This study was originally conceived to test in a rigorous way the specificity of three major approaches to high-throughput array-based DNA methylation analysis: (1) MeDIP, or methylated DNA...
Korshunova, Yulia, Maloney, Rebecca K., Lakey, Nathan, Citek, Robert W., Bacher, Blaire, Budiman, Arief, ...
Cytosine-methylation changes are stable and thought to be among the earliest events in tumorigenesis. Theoretically, DNA carrying tumor-specifying methylation patterns escape the tumors and may be...
Sorghum Genome Sequencing by Methylation Filtration (2005)
Joseph A. Bedell, Muhammad A. Budiman, Andrew Nunberg, Robert W. Citek, Dan Robbins, Joshua Jones, ...
Methylation filtration makes practical the sequencing of large genomes, such as those found in sorghum, by preferentially capturing functionally relevant sequences.
Sorghum Genome Sequencing by Methylation Filtration (2005)
Joseph A. Bedell, Muhammad A. Budiman, Andrew Nunberg, Robert W. Citek, Dan Robbins, Joshua Jones, ...
Sorghum bicolor is a close relative of maize and is a staple crop in Africa and much of the developing world because of its superior tolerance of arid growth conditions. We have generated sequence...
Ulrich, Ricky L., DeShazer, David, Hines, Harry B., Jeddeloh, Jeffrey A.
Numerous gram-negative bacterial pathogens regulate virulence factor expression by using a cell density mechanism termed quorum sensing (QS). An in silico analysis of the Burkholderia mallei ATCC...
Ulrich, Ricky L., DeShazer, David, Hines, Harry B., Jeddeloh, Jeffrey A.
Numerous gram-negative bacterial pathogens regulate virulence factor expression by using a cell density mechanism termed quorum sensing (QS). An in silico analysis of the Burkholderia mallei ATCC...
Characterization of an Arabidopsis thaliana DNA hypomethylation mutant (1995)
Kakutani, Tetsuji, Jeddeloh, Jeffrey A., Richards, Eric J.
We have recently isolated two Arabidopsis thaliana DNA hypomethylation mutations, identifying the DDM1 locus, that cause a 70% reduction in genomic 5- methylcytosine levels [1]. Here we describe...
Burkholderia thailandensis E125 Harbors a Temperate Bacteriophage Specific for Burkholderia mallei
Woods, Donald E., Jeddeloh, Jeffrey A., Fritz, David L., DeShazer, David
Burkholderia thailandensis is a nonpathogenic gram-negative bacillus that is closely related to Burkholderia mallei and Burkholderia pseudomallei. We found that B. thailandensis E125 spontaneously...
The DNA methylation locus DDM1 is required for maintenance of gene silencing in Arabidopsis
Jeddeloh, Jeffrey A., Bender, Judith, Richards, Eric J.
To investigate the relationship between cytosine methylation and gene silencing in Arabidopsis, we constructed strains containing the ddm1 hypomethylation mutation and a methylated and silenced PAI2...
Ulrich, Ricky L., Hines, Harry B., Parthasarathy, N., Jeddeloh, Jeffrey A.
Numerous gram-negative bacteria communicate and regulate gene expression through a cell density-responsive mechanism termed quorum sensing (QS), which involves the synthesis and perception of...
Ulrich, Ricky L., DeShazer, David, Hines, Harry B., Jeddeloh, Jeffrey A.
Numerous gram-negative bacterial pathogens regulate virulence factor expression by using a cell density mechanism termed quorum sensing (QS). An in silico analysis of the Burkholderia mallei ATCC...
Sorghum Genome Sequencing by Methylation Filtration
Bedell, Joseph A, Budiman, Muhammad A, Nunberg, Andrew, Citek, Robert W, Robbins, Dan, Jones, Joshua, ...
Sorghum bicolor is a close relative of maize and is a staple crop in Africa and much of the developing world because of its superior tolerance of arid growth conditions. We have generated sequence...
Arabidopsis MET1 cytosine methyltransferase mutants.
Kankel, Mark W, Ramsey, Douglas E, Stokes, Trevor L, Flowers, Susan K, Haag, Jeremy R, Jeddeloh, Jeffrey A, ...
We describe the isolation and characterization of two missense mutations in the cytosine-DNA-methyltransferase gene, MET1, from the flowering plant Arabidopsis thaliana. Both missense mutations,...
Burkholderia thailandensis E125 Harbors a Temperate Bacteriophage Specific for Burkholderia mallei
Woods, Donald E., Jeddeloh, Jeffrey A., Fritz, David L., DeShazer, David
Burkholderia thailandensis is a nonpathogenic gram-negative bacillus that is closely related to Burkholderia mallei and Burkholderia pseudomallei. We found that B. thailandensis E125 spontaneously...
The DNA methylation locus DDM1 is required for maintenance of gene silencing in Arabidopsis
Jeddeloh, Jeffrey A., Bender, Judith, Richards, Eric J.
To investigate the relationship between cytosine methylation and gene silencing in Arabidopsis, we constructed strains containing the ddm1 hypomethylation mutation and a methylated and silenced PAI2...
Ulrich, Ricky L., Hines, Harry B., Parthasarathy, N., Jeddeloh, Jeffrey A.
Numerous gram-negative bacteria communicate and regulate gene expression through a cell density-responsive mechanism termed quorum sensing (QS), which involves the synthesis and perception of...
Ulrich, Ricky L., DeShazer, David, Hines, Harry B., Jeddeloh, Jeffrey A.
Numerous gram-negative bacterial pathogens regulate virulence factor expression by using a cell density mechanism termed quorum sensing (QS). An in silico analysis of the Burkholderia mallei ATCC...
Sorghum Genome Sequencing by Methylation Filtration
Bedell, Joseph A, Budiman, Muhammad A, Nunberg, Andrew, Citek, Robert W, Robbins, Dan, Jones, Joshua, ...
Sorghum bicolor is a close relative of maize and is a staple crop in Africa and much of the developing world because of its superior tolerance of arid growth conditions. We have generated sequence...
Arabidopsis MET1 cytosine methyltransferase mutants.
Kankel, Mark W, Ramsey, Douglas E, Stokes, Trevor L, Flowers, Susan K, Haag, Jeremy R, Jeddeloh, Jeffrey A, ...
We describe the isolation and characterization of two missense mutations in the cytosine-DNA-methyltransferase gene, MET1, from the flowering plant Arabidopsis thaliana. Both missense mutations,...
Identification of Novel High-Frequency DNA Methylation Changes in Breast Cancer
Ordway, Jared M., Budiman, Muhammad A., Korshunova, Yulia, Maloney, Rebecca K., Bedell, Joseph A., Citek, Robert W., ...
Recent data have revealed that epigenetic alterations, including DNA methylation and chromatin structure changes, are among the earliest molecular abnormalities to occur during tumorigenesis. The...
Korshunova, Yulia, Maloney, Rebecca K., Lakey, Nathan, Citek, Robert W., Bacher, Blaire, Budiman, Arief, ...
Cytosine-methylation changes are stable and thought to be among the earliest events in tumorigenesis. Theoretically, DNA carrying tumor-specifying methylation patterns escape the tumors and may be...
Reduced-representation methylation mapping
Jeddeloh, Jeffrey A, Greally, John M, Rando, Oliver J
Massively parallel sequencing has been harnessed to map DNA methylation patterns in the mouse genome.
Comprehensive high-throughput arrays for relative methylation (CHARM)
Irizarry, Rafael A., Ladd-Acosta, Christine, Carvalho, Benilton, Wu, Hao, Brandenburg, Sheri A., Jeddeloh, Jeffrey A., ...
This study was originally conceived to test in a rigorous way the specificity of three major approaches to high-throughput array-based DNA methylation analysis: (1) MeDIP, or methylated DNA...