Corrigendum: High-throughput oncogene mutation profiling in human cancer. (2007)
Thomas, Roman K, Baker, Alissa C, Debiasi, Ralph M, Winckler, Wendy, Laframboise, Thomas, Lin, William M, ...
Systematic efforts are underway to decipher the genetic changes associated with tumor initiation and progression1, 2. However, widespread clinical application of this information is hampered by an...
High-throughput oncogene mutation profiling in human cancer (2007)
Thomas, Roman K., Baker, Alissa C., Debiasi, Ralph M., Winckler, Wendy, Laframboise, Thomas, Lin, William M., ...
Lee, Jeffrey C, Vivanco, Igor, Beroukhim, Rameen, Huang, Julie H Y, Feng, Whei L, Debiasi, Ralph M, ...
BACKGROUND: Protein tyrosine kinases are important regulators of cellular homeostasis with tightly controlled catalytic activity. Mutations in kinase-encoding genes can relieve the autoinhibitory...
Lee, Jeffrey C, Vivanco, Igor, Beroukhim, Rameen, Huang, Julie H Y, Feng, Whei L, Debiasi, Ralph M, ...
Background Protein tyrosine kinases are important regulators of cellular homeostasis with tightly controlled catalytic activity. Mutations in kinase-encoding genes can relieve the autoinhibitory...
Jeffrey C. Lee, Igor Vivanco, Rameen Beroukhim, Whei L. Feng, Ralph M. DeBiasi, ...
BackgroundProtein tyrosine kinases are important regulators of cellular homeostasis with tightly controlled catalytic activity. Mutations in kinase-encoding genes can relieve the autoinhibitory...
Thomas, Roman K., Nickerson, Elizabeth, Simons, Jan F., Jänne, Pasi A., Tengs, Torstein, Yuza, Yuki, ...
EGFR activation in glioblastoma through novel missense mutations in the extracellular domain (2006)
Lee, Jeffrey C., Huang, Julie H.Y., Beroukhim, Rameen, Feng, Whei L., DeBiasi, R.M., King, J.C., ...
Wadleigh, Martha, Ebert, Benjamin L, Wernig, Gerlinde, Huntly, Brian J P, ...
Polycythemia vera (PV), essential thrombocythemia (ET), and myeloid metaplasia with myelofibrosis (MMM) are clonal disorders arising from hematopoietic progenitors. An internet-based protocol was...
Paez, J. Guillermo, Lin, Ming, Beroukhim, Rameen, Lee, Jeffrey C., Zhao, Xiaojun, Richter, Daniel J., ...
Major efforts are underway to systematically define the somatic and germline genetic variations causally associated with disease. Genome‐wide genetic analysis of actual clinical samples is,...
Vol Suppl Pages, Oliver D. King, Jeffrey C. Lee, Aimée M. Dudley, Daniel M, George M. Church, ...
Motivation: Predicting the outcome of specific experiments (such as the growth of a particular mutant strain in a particular medium) has the potential to allow researchers to devote resources to...
Predicting phenotype from patterns of annotation (2003)
King, Oliver D., Lee, Jeffrey C., Dudley, Aimée M., Janse, Daniel M., Church, George M., Roth, Frederick P.
Motivation:Predicting the outcome of specific experiments (such as the growth of a particular mutant strain in a particular medium) has the potential to allow researchers to devote resources to...
Roles of Nkx2.2 and Ngn3 in vertebrate gliogenesis in the developing spinal cord. (2002)
The vertebrate central nervous system (CNS) comprises of two types of cell: neurons and glia. In the developing vertebrate neural tube, glia consists of astrocytes, olegodendrocytes and radial glia....
The roles of Nkx2.2 and Ngn3 in vertebrate gliogenesis in the developing spinal cord / (2002)
Thesis (Ph. D.)--Dept. of Neurobiology and Anatomy, University of Utah, 2002.
Microform : Ann Arbor, MI : University Microfilms.--1 microfilm reel ; 35 mm.
Scacheri, Peter C., Rozenblatt-Rosen, Orit, Caplen, Natasha J., Wolfsberg, Tyra G., Umayam, Lowell, Lee, Jeffrey C., ...
RNA interference (RNAi) mediated by short interfering RNAs (siRNAs) is a widely used method to analyze gene function. To use RNAi knockdown accurately to infer gene function, it is essential to...
Paez, J. Guillermo, Lin, Ming, Beroukhim, Rameen, Lee, Jeffrey C., Zhao, Xiaojun, Richter, Daniel J., ...
Major efforts are underway to systematically define the somatic and germline genetic variations causally associated with disease. Genome-wide genetic analysis of actual clinical samples is, however,...
Scacheri, Peter C., Rozenblatt-Rosen, Orit, Caplen, Natasha J., Wolfsberg, Tyra G., Umayam, Lowell, Lee, Jeffrey C., ...
RNA interference (RNAi) mediated by short interfering RNAs (siRNAs) is a widely used method to analyze gene function. To use RNAi knockdown accurately to infer gene function, it is essential to...
Paez, J. Guillermo, Lin, Ming, Beroukhim, Rameen, Lee, Jeffrey C., Zhao, Xiaojun, Richter, Daniel J., ...
Major efforts are underway to systematically define the somatic and germline genetic variations causally associated with disease. Genome-wide genetic analysis of actual clinical samples is, however,...
Lee, Jeffrey C, Vivanco, Igor, Beroukhim, Rameen, Huang, Julie H. Y, Feng, Whei L, DeBiasi, Ralph M, ...
Ingo Mellinghoff and colleagues sequenced theEGFR gene in glioblastoma samples and cell lines and identified missense mutations in the extracellular domain that suggest a new mechanism for EGFR...
Beroukhim, Rameen, Getz, Gad, Nghiemphu, Leia, Barretina, Jordi, Hsueh, Teli, Linhart, David, ...
Comprehensive knowledge of the genomic alterations that underlie cancer is a critical foundation for diagnostics, prognostics, and targeted therapeutics. Systematic efforts to analyze cancer genomes...