Jeffrey J. Coleman

Efflux in Fungi: La Pièce de Résistance

Coleman, Jeffrey J., Mylonakis, Eleftherios

Pathogens must be able to overcome both host defenses and antimicrobial treatment in order to successfully infect and maintain colonization of the host. One way fungi accomplish this feat and...

The Genome of Nectria haematococca: Contribution of Supernumerary Chromosomes to Gene Expansion

Coleman, Jeffrey J., Rounsley, Steve D., Rodriguez-Carres, Marianela, Kuo, Alan, Wasmann, Catherine C., Grimwood, Jane, ...

The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of >50 species known as the “Fusarium solani species complex”. Members of this complex have...

Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

Okoli, Ikechukwu, Coleman, Jeffrey J., Tempakakis, Emmanouil, An, W. Frank, Holson, Edward, Wagner, Florence, ...

Candida albicans, the most common human pathogenic fungus, can establish a persistent lethal infection in the intestine of the microscopic nematode Caenorhabditis elegans. The C. elegans–C....