In twenty years of asbestos litigation, procedural reforms at all levels of the civil litigation system have failed to reduce plaintiffs' attorneys' fees. The result has been dramatic...
Broadley, Caroline, Gonzalez, Debra A., Nair, Rhada, Davidson, Jeffrey M.
Fibroblasts from canine vocal fold tissue have been isolated and maintained in culture. These cells express vimentin and a-smooth muscle actin, the characteristic marker of myofibroblast...
Nishida, Masashi, Fujinaka, Hidehiko, Matsusaka, Taiji, Price, James, Kon, Valentina, Fogo, Agnes B., ...
We examined the in vivo function of the angiotensin II type 1 receptor (Agtr1) on macrophages in renal fibrosis. Fourteen days after the induction of unilateral ureteral obstruction (UUO), wild-type...
Nishida, Masashi, Fujinaka, Hidehiko, Matsusaka, Taiji, Price, James, Kon, Valentina, Fogo, Agnes B., ...
We examined the in vivo function of the angiotensin II type 1 receptor (Agtr1) on macrophages in renal fibrosis. Fourteen days after the induction of unilateral ureteral obstruction (UUO), wild-type...
Shi, Yubin, Reitmaier, Birgit, Regenbogen, Johannes, Slowey, R. Michael, Opalenik, Susan R., Wolf, Eckhard, ...
Cardiac ankyrin repeat protein (CARP) was identified by subtractive hybridization as one of a group of genes that are rapidly modulated by acute wounding of mouse skin. Quantitative RT-PCR showed...
Plasmin Modulates Vascular Endothelial Growth Factor-A-Mediated Angiogenesis during Wound Repair
Roth, Detlev, Piekarek, Michael, Paulsson, Mats, Christ, Hildegard, Bloch, Wilhelm, Krieg, Thomas, ...
Plasmin-catalyzed cleavage of the vascular endothelial growth factor (VEGF)-A isoform VEGF165 results in loss of its carboxyl-terminal heparin-binding domain and significant loss in its bioactivity....
Ma, Li-Jun, Yang, Haichun, Gaspert, Ariana, Carlesso, Gianluca, Barty, Melissa M., Davidson, Jeffrey M., ...
Transforming growth factor-β1 (TGF-β1) and the renin-angiotensin-aldosterone system are key mediators in kidney fibrosis. Integrin αvβ6, a heterodimeric matrix receptor expressed in epithelia,...
Accelerated Wound Closure in Mice Deficient for Interleukin-10
Eming, Sabine A., Werner, Sabine, Bugnon, Philippe, Wickenhauser, Claudia, Siewe, Lisa, Utermöhlen, Olaf, ...
The impact of the local inflammatory response on the process of wound healing has been debated for decades. In particular, the question whether infiltrating macrophages and granulocytes promote or...
Pyle, Amy L., Atkinson, James B., Pozzi, Ambra, Reese, Jeff, Eckes, Beate, Davidson, Jeffrey M., ...
Atherosclerotic plaques express high levels of small proline-rich repeat protein (SPRR3), a previously characterized component of the cornified cell envelope of stratified epithelia, where it is...
Alfaro, Maria P., Pagni, Matthew, Vincent, Alicia, Atkinson, James, Hill, Michael F., Cates, Justin, ...
Cell-based therapies, using multipotent mesenchymal stem cells (MSCs) for organ regeneration, are being pursued for cardiac disease, orthopedic injuries and biomaterial fabrication. The molecular...