Jeffrey M. Stadel

Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway (1990)

Kang, Yoon-Se, Kane, Jeffrey, Kurjan, Janet, Stadel, Jeffrey M., Tipper, Donald J.

Scg1, the product of the Saccharomyces cerevisiae SCG1 (also called GPA1) gene, is homologous to the alpha subunits of G proteins involved in signal transduction in mammalian cells. Scg1 negatively...

Orphan G-protein-coupled receptors: the next generation of drug targets?

Wilson, Shelagh, Bergsma, Derk J, Chambers, Jon K, Muir, Alison I, Fantom, Kenneth G M, Ellis, Catherine, ...

The pharmaceutical industry has readily embraced genomics to provide it with new targets for drug discovery. Large scale DNA sequencing has allowed the identification of a plethora of DNA sequences...