Johnson, Anthony C., Myers, Brent, Lazovic, Jelena, Towner, Rheal, Greenwood-Van Meerveld, Beverley
Background: Although visceral pain of gastrointestinal (GI) origin is the major complaint in patients with irritable bowel syndrome (IBS) it remains poorly understood. Brain imaging studies suggest a...
Zinnanti, William J., Lazovic, Jelena
Glutaric aciduria type I (GA-1) results from an inherited defect in a common step of lysine, hydroxylysine and tryptophan metabolism. This defect is associated with an age-dependent susceptibility to...
Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease (2009)
Zinnanti, William J., Lazovic, Jelena, Griffin, Kathleen, Skvorak, Kristen J., Paul, Harbhajan S., Homanics, Gregg E., ...
Maple syrup urine disease (MSUD) is an inherited disorder of branched-chain amino acid metabolism presenting with lifethreatening cerebral oedema and dysmyelination in affected individuals. Treatment...
Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease (2009)
Zinnanti, William J., Lazovic, Jelena, Griffin, Kathleen, Skvorak, Kristen J., Paul, Harbhajan S., Homanics, Gregg E., ...
Maple syrup urine disease (MSUD) is an inherited disorder of branched-chain amino acid metabolism presenting with life-threatening cerebral oedema and dysmyelination in affected individuals....
Zinnanti, William J., Lazovic, Jelena, Housman, Cathy, LaNoue, Kathryn, O'Callaghan, James P., Simpson, Ian, ...
Glutaric acidemia type I (GA-I) is an inherited disorder of lysine and tryptophan metabolism presenting with striatal lesions anatomically and symptomatically similar to Huntington disease. Affected...
Strauss, Kevin A., Lazovic, Jelena, Wintermark, Max, Morton, D. Holmes
Despite early diagnosis, one-third of Amish infants with glutaryl-CoA dehydrogenase deficiency (GA1) develop striatal lesions that leave them permanently disabled. To better understand mechanisms of...
Applications of Magnetic Resonance Imaging to Study Brain Pathology and Function (2006)
Magnetic resonance imaging utilizes magnetic fields to non-invasively manipulate atomic nuclei to allow creation of images from regions within a body otherwise obscured from sight. Here we use the...
A diet-induced mouse model for glutaric aciduria type I (2006)
Zinnanti, William J., Lazovic, Jelena, Wolpert, Ellen B., Antonetti, David A., Smith, Michael B., Connor, James R., ...
In the autosomal recessive human disease, glutaric aciduria type I (GA-1), glutaryl-CoA dehydrogenase (GCDH) deficiency disrupts the mitochondrial catabolism of lysine and tryptophan. Affected...
A diet-induced mouse model for glutaric aciduria type I (2006)
Zinnanti, William J., Lazovic, Jelena, Wolpert, Ellen B., Antonetti, David A., Smith, Michael B., Connor, James R., ...
In the autosomal recessive human disease, glutaric aciduria type I (GA-1), glutaryl-CoA dehydrogenase (GCDH) deficiency disrupts the mitochondrial catabolism of lysine and tryptophan. Affected...
New insights for glutaric aciduria type I (2006)
Zinnanti, William J., Lazovic, Jelena, Wolpert, Ellen B., Antonetti, David A., Smith, Michael B., Connor, James R., ...
A diet-induced mouse model for glutaric aciduria type I (2006)
Zinnanti, William J., Lazovic, Jelena, Wolpert, Ellen B., Antonetti, David A., Smith, Michael B., Connor, James R., ...
In the autosomal recessive human disease, glutaric aciduria type I (GA-1), glutaryl-CoA dehydrogenase (GCDH) deficiency disrupts the mitochondrial catabolism of lysine and tryptophan. Affected...
Anirban Basu, Jelena Lazovic, J Kyle Krady, David T Mauger, Raymond P Rothstein, Michael B Smith, ...
Anirban Basu, Jelena Lazovic, J Kyle Krady, David T Mauger, Raymond P Rothstein, Michael B Smith, ...
Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease
Zinnanti, William J., Lazovic, Jelena, Griffin, Kathleen, Skvorak, Kristen J., Paul, Harbhajan S., Homanics, Gregg E., ...
Maple syrup urine disease (MSUD) is an inherited disorder of branched-chain amino acid metabolism presenting with life-threatening cerebral oedema and dysmyelination in affected individuals....