E. Nancy Miller, Manal Fadl, Hiba S. Mohamed, Abier Elzein, Sarra E. Jamieson, Heather J. Cordell, ...
Familial clustering and ethnic differences suggest that visceral leishmaniasis caused by Leishmania donovani is under genetic control. A recent genome scan provided evidence for a major...
E. Nancy Miller, Manal Fadl, Hiba S Mohamed, Abier Elzein, Sarra E Jamieson, Heather J Cordell, ...
Familial clustering and ethnic differences suggest that visceral leishmaniasis (VL) caused by Leishmania donovani is under genetic control. A recent genome scan provided evidence for a major...
Immunostimulatory DNA as an Adjuvant in Vaccination against Leishmania major
Stacey, Katryn J., Blackwell, Jenefer M.
Oligodeoxynucleotides (ODN) which contain immunostimulatory CG motifs (CpG ODN) can promote T helper 1 (Th1) responses, an adjuvant activity that is desirable for vaccination against leishmaniasis....
Soo, Shiu-Shing, Villarreal-Ramos, Bernardo, Khan, C. M. Anjam, Hormaeche, Carlos E., Blackwell, Jenefer M.
Attenuated strains of Salmonella typhimurium have been widely used as vehicles for delivery and expression of vaccine antigens in murine models of infectious disease. In mice, early bacterial...
Weir, Rosemary E., Black, Gillian F., Dockrell, Hazel M., Floyd, Sian, Fine, Paul E. M., Chaguluka, Steven D., ...
To investigate the role of innate immunity in variable efficacy of Mycobacterium bovis BCG vaccination in Malawi and the United Kingdom, we examined 24-h tumor necrosis factor alpha, interleukin-1β...
Lange, Uta G., Mastroeni, Pietro, Blackwell, Jenefer M., Stober, Carmel B.
Successful resolution of infections by intracellular pathogens requires gamma interferon (IFN-γ). DNA vaccines promote T helper 1 (Th1) responses by triggering interleukin-12 (IL-12) release by...
Mulero, Victoriano, Searle, Susan, Blackwell, Jenefer M, Brock, Jeremy H
Solute carrier 11a1 (Slc11a1; formerly Nramp1; where Nramp stands for natural-resistance-associated macrophage protein) is a proton/bivalent cation antiporter that localizes to late...
Roberts, Mark T. M., Stober, Carmel B., McKenzie, Andrew N, Blackwell, Jenefer M.
Leishmaniasis affects 12 million people but there are no vaccines in routine use. Recently, we used DNA vaccination in a susceptible BALB/c high-dose model of infection to screen 100 novel Leishmania...
The Genome of the Kinetoplastid Parasite, Leishmania major
Ivens, Alasdair C., Peacock, Christopher S., Worthey, Elizabeth A., Murphy, Lee, Aggarwal, Gautam, Berriman, Matthew, ...
Immunostimulatory DNA as an Adjuvant in Vaccination against Leishmania major
Stacey, Katryn J., Blackwell, Jenefer M.
Oligodeoxynucleotides (ODN) which contain immunostimulatory CG motifs (CpG ODN) can promote T helper 1 (Th1) responses, an adjuvant activity that is desirable for vaccination against leishmaniasis....
Soo, Shiu-Shing, Villarreal-Ramos, Bernardo, Khan, C. M. Anjam, Hormaeche, Carlos E., Blackwell, Jenefer M.
Attenuated strains of Salmonella typhimurium have been widely used as vehicles for delivery and expression of vaccine antigens in murine models of infectious disease. In mice, early bacterial...
Weir, Rosemary E., Black, Gillian F., Dockrell, Hazel M., Floyd, Sian, Fine, Paul E. M., Chaguluka, Steven D., ...
To investigate the role of innate immunity in variable efficacy of Mycobacterium bovis BCG vaccination in Malawi and the United Kingdom, we examined 24-h tumor necrosis factor alpha, interleukin-1β...
Lange, Uta G., Mastroeni, Pietro, Blackwell, Jenefer M., Stober, Carmel B.
Successful resolution of infections by intracellular pathogens requires gamma interferon (IFN-γ). DNA vaccines promote T helper 1 (Th1) responses by triggering interleukin-12 (IL-12) release by...
Mulero, Victoriano, Searle, Susan, Blackwell, Jenefer M, Brock, Jeremy H
Solute carrier 11a1 (Slc11a1; formerly Nramp1; where Nramp stands for natural-resistance-associated macrophage protein) is a proton/bivalent cation antiporter that localizes to late...
Roberts, Mark T. M., Stober, Carmel B., McKenzie, Andrew N, Blackwell, Jenefer M.
Leishmaniasis affects 12 million people but there are no vaccines in routine use. Recently, we used DNA vaccination in a susceptible BALB/c high-dose model of infection to screen 100 novel Leishmania...
From genomes to vaccines: Leishmania as a model.
Almeida, Renata, Norrish, Alan, Levick, Mark, Vetrie, David, Freeman, Tom, Vilo, Jaak, ...
The 35 Mb genome of Leishmania should be sequenced by late 2002. It contains approximately 8500 genes that will probably translate into more than 10 000 proteins. In the laboratory we have been...
Miller, E. Nancy, Fadl, Manal, Mohamed, Hiba S, Elzein, Abier, Jamieson, Sarra E, Cordell, Heather J, ...
Familial clustering and ethnic differences suggest that visceral leishmaniasis caused by Leishmania donovani is under genetic control. A recent genome scan provided evidence for a major...
Stober, Carmel B., Lange, Uta G., Roberts, Mark T. M., Alcami, Antonio, Blackwell, Jenefer M.
Leishmaniasis affects 12 million people, but there are no vaccines in routine clinical use. Th1 polarizing vaccines that elicit long-term protection are required to prevent disease in susceptible...
Stober, Carmel B., Brode, Sven, White , Jacqueline K., Popoff, Jean-François, Blackwell, Jenefer M.
Solute carrier family 11 member a1 (Slc11a1; formerly Nramp1) encodes a late endosomal/lysosomal protein/divalent cation transporter that regulates iron homeostasis in macrophages. During macrophage...