Jennifer A. Marshall Graves

Does the human X contain a third evolutionary block? Origin of genes on human Xp11 and Xq28 (2009)

Delbridge, Margaret L., Patel, Hardip R., Waters, Paul D., McMillan, Daniel A., Marshall Graves, Jennifer A.

Comparative gene mapping of human X-borne genes in marsupials defined an ancient conserved region and a recently added region of the eutherian X, and the separate evolutionary origins of these...

Recombination and Nucleotide Diversity in the Sex Chromosomal Pseudoautosomal Region of the Emu, Dromaius novaehollandiae (2009)

Janes, Daniel E., Ezaz, Tariq, Marshall Graves, Jennifer A., Edwards, Scott V.

Pseudoautosomal regions (PARs) shared by avian Z and W sex chromosomes are typically small homologous regions within which recombination still occurs and are hypothesized to share the properties of...

Genome analysis of the platypus reveals unique signatures of evolution (2008)

Warren, Wesley C., Hillier, LaDeana W., Marshall Graves, Jennifer A., Birney, Ewan, Ponting, Chris P., Grützner, Frank, ...

We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a...

RBMX gene is essential for brain development in Zebrafish (2005)

Tsend-Ayush, Enkhjargal, O`Sullivan, Lynda A., Grutzner, Frank S., Onnebo, Sara M.N., Lewis, Rowena S., Delbridge, Margaret L., ...

The human RBMX gene was discovered recently through its homology to the spermatogenesis candidate gene RBMY. Its position on the human X chromosome suggests that it may be involved in X-linked mental...

RBMX gene is essential for brain development in Zebrafish (2005)

Tsend-Ayush, Enkhjargal, O`Sullivan, Lynda A., Grutzner, Frank S., Onnebo, Sara M.N., Lewis, Rowena S., Delbridge, Margaret L., ...

The human RBMX gene was discovered recently through its homology to the spermatogenesis candidate gene RBMY. Its position on the human X chromosome suggests that it may be involved in X-linked mental...

In the platypus a meiotic chain of ten sex chromosomes shares genes with the bird Z and mammal X chromosomes (2004)

Grutzner, Frank, Rens, Willem, Tsend-Ayush, Enkhjargal, El-Mogharbel, Nisrine, O'Brien, Patricia C. M., Jones, Russell C., ...

Two centuries after the duck-billed platypus was discovered, monotreme chromosome systems remain deeply puzzling. Karyotypes of males, or of both sexes, were claimed to contain several unpaired...

In the platypus a meiotic chain of ten sex chromosomes shares genes with the bird Z and mammal X chromosomes (2004)

Grutzner, Frank, Rens, Willem, Tsend-Ayush, Enkhjargal, El-Mogharbel, Nisrine, O'Brien, Patricia C. M., Jones, Russell C., ...

Two centuries after the duck-billed platypus was discovered, monotreme chromosome systems remain deeply puzzling. Karyotypes of males, or of both sexes, were claimed to contain several unpaired...

Evolution of vertebrate genes related to Prion and Shadoo proteins - clues from comparative genomic analysis (2004)

Premzl, Marko, Gready, Jill E., Jermiin, Lars S., Simonic, Tatjana, Marshall Graves, Jennifer A.

Recent findings of new genes in fish related to the prion protein (PrP) gene PRNP, including our recent report of SPRN coding for Shadoo (Sho) protein found also in mammals, raise issues of their...

Evolution of Vertebrate Genes Related to Prion and Shadoo Proteins--Clues from Comparative Genomic Analysis (2004)

Premzl, Marko, Gready, Jill E., Jermiin, Lars S., Simonic, Tatjana, Marshall Graves, Jennifer A.

Recent findings of new genes in fish related to the prion protein (PrP) gene PRNP, including our recent report of SPRN coding for Shadoo (Sho) protein found also in mammals, raise issues of their...

Evolution of vertebrate genes related to Prion and Shadoo proteins - clues from comparative genomic analysis (2004)

Premzl, Marko, Gready, Jill E., Jermiin, Lars S., Simonic, Tatjana, Marshall Graves, Jennifer A.

Recent findings of new genes in fish related to the prion protein (PrP) gene PRNP, including our recent report of SPRN coding for Shadoo (Sho) protein found also in mammals, raise issues of their...

The human sex-reversing ATRX gene has a homologue on the marsupial Y chromosome, ATRY: Implications for the evolution of mammalian sex determination

Pask, Andrew, Renfree, Marilyn B., Marshall Graves, Jennifer A.

Mutations in the ATRX gene on the human X chromosome cause X-linked α-thalassemia and mental retardation. XY patients with deletions or mutations in this gene display varying degrees of sex...

The X and Y Chromosomes Assemble into H2A.Z, Containing Facultative Heterochromatin, following Meiosis

Greaves, Ian K., Rangasamy, Danny, Devoy, Michael, Marshall Graves, Jennifer A., Tremethick, David J.

Spermatogenesis is a complex sequential process that converts mitotically dividing spermatogonia stem cells into differentiated haploid spermatozoa. Not surprisingly, this process involves dramatic...

The human sex-reversing ATRX gene has a homologue on the marsupial Y chromosome, ATRY: Implications for the evolution of mammalian sex determination

Pask, Andrew, Renfree, Marilyn B., Marshall Graves, Jennifer A.

Mutations in the ATRX gene on the human X chromosome cause X-linked α-thalassemia and mental retardation. XY patients with deletions or mutations in this gene display varying degrees of sex...

The X and Y Chromosomes Assemble into H2A.Z, Containing Facultative Heterochromatin, following Meiosis

Greaves, Ian K., Rangasamy, Danny, Devoy, Michael, Marshall Graves, Jennifer A., Tremethick, David J.

Spermatogenesis is a complex sequential process that converts mitotically dividing spermatogonia stem cells into differentiated haploid spermatozoa. Not surprisingly, this process involves dramatic...

Retrotransposon Silencing by DNA Methylation Can Drive Mammalian Genomic Imprinting

Suzuki, Shunsuke, Ono, Ryuichi, Narita, Takanori, Pask, Andrew J, Shaw, Geoffrey, Wang, Changshan, ...

Among mammals, only eutherians and marsupials are viviparous and have genomic imprinting that leads to parent-of-origin-specific differential gene expression. We used comparative analysis to...

Frequency of Cancer Genes on the Chicken Z Chromosome and Its Human Homologues: Implications for Sex Chromosome Evolution

Stiglec, Rami, Kohn, Matthias, Fong, James, Ezaz, Tariq, Hameister, Horst, Marshall Graves, Jennifer A.

It has been suggested that there are special evolutionary forces that act on sex chromosomes. Hemizygosity of the X chromosome in male mammals has led to selection for male-advantage genes, and...

The Status of Dosage Compensation in the Multiple X Chromosomes of the Platypus

Deakin, Janine E., Hore, Timothy A., Koina, Edda, Marshall Graves, Jennifer A.

Dosage compensation has been thought to be a ubiquitous property of sex chromosomes that are represented differently in males and females. The expression of most X-borne genes is equalized between XX...

The Evolution of Epigenetic Regulators CTCF and BORIS/CTCFL in Amniotes

Hore, Timothy A., Deakin, Janine E., Marshall Graves, Jennifer A.

CTCF is an essential, ubiquitously expressed DNA-binding protein responsible for insulator function, nuclear architecture, and transcriptional control within vertebrates. The gene CTCF was proposed...

Does the human X contain a third evolutionary block? Origin of genes on human Xp11 and Xq28

Delbridge, Margaret L., Patel, Hardip R., Waters, Paul D., McMillan, Daniel A., Marshall Graves, Jennifer A.

Comparative gene mapping of human X-borne genes in marsupials defined an ancient conserved region and a recently added region of the eutherian X, and the separate evolutionary origins of these...

A simple non-invasive protocol to establish primary cell lines from tail and toe explants for cytogenetic studies in Australian dragon lizards (Squamata: Agamidae)

Ezaz, Tariq, O’Meally, Denis, Quinn, Alexander E., Sarre, Stephen D., Georges, Arthur, Marshall Graves, Jennifer A.

Primary cell lines were established from cultures of tail and toe clips of five species of Australian dragon lizards: Tympanocryptis pinguicolla, Tympanocryptis sp., Ctenophorus fordi, Amphibolurus...