Jennifer Fostel

Promoting coherent minimum reporting requirements for biological and biomedical investigations : The MIBBI Project. (2008)

Taylor, Chris, Field, Dawn, Sansone, Susanna-Assunta, Apweiler, Rolf, Ashburner, Michael, Ball, Cathy, ...

The Minimum Information for Biological and Biomedical Investigations (MIBBI) project aims to foster the coordinated development of minimum-information checklists and provide a resource for those...

Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project (2008)

Taylor, Chris F., Field, Dawn, Sansone, Susanna-Assunta, Aerts, Jan, Apweiler, Rolf, Asburner, Michael, ...

The Minimum Information for Biological and Biomedical Investigations (MIBBI) project provides a resource for those exploring the range of extant minimum information checklists and fosters coordinated...

Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories (2008)

Boedigheimer, Michael J, Wolfinger, Russell D, Bass, Michael B, Bushel, Pierre R, Chou, Jeff W, Cooper, Matthew, ...

Abstract Background The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variance due to individual, environmental, and...

The First RSBI (ISA-TAB) Workshop: "Can a Simple Format Work for Complex Studies?" (2008)

Sansone, Susanna-Assunta, Rocca-Serra, Philippe, Brandizi, Marco, Brazma, Alvis, Field, Dawn, Fostel, Jennifer, ...

This article summarizes the motivation for, and the proceedings of, the first ISA-TAB workshop held December 6–8, 2007, at the EBI, Cambridge, UK. This exploratory workshop, organized by members of...

CEBS Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data (2008)

Waters, Michael, Stasiewicz, Stanley, Alex Merrick, B., Tomer, Kenneth, Bushel, Pierre, Paules, Richard, ...

CEBS (Chemical Effects in Biological Systems) is an integrated public repository for toxicogenomics data, including the study design and timeline, clinical chemistry and histopathology findings and...

Standardization Initiatives in the (eco)toxicogenomics Domain: A Review (2006)

Susanna Assunta Sansone, Norman Morrison, Philippe Rocca-Serra, Jennifer Fostel

The purpose of this document is to provide readers with a resource of different ongoing standardization efforts within the ‘omics’ (genomic, proteomics, metabolomics) and...

The MGED Ontology: a resource for semantics-based description of microarray experiments (2006)

Whetzel, Patricia L., Parkinson, Helen, Causton, Helen C., Fan, Liju, Fostel, Jennifer, Fragoso, Gilberto, ...

Motivation: The generation of large amounts of microarray data and the need to share these data bring challenges for both data management and annotation and highlights the need for standards. MIAME...

Chemical effects in biological systems (CEBS) object model for toxicology data, SysTox-OM: design and application (2006)

Xirasagar, Sandhya, Gustafson, Scott F., Huang, Cheng-Cheng, Pan, Qinyan, Fostel, Jennifer, Boyer, Paul, ...

Motivation: The CEBS data repository is being developed to promote a systems biology approach to understand the biological effects of environmental stressors. CEBS will house data from multiple gene...

A proposed semantic framework for reporting omics investigations (2005)

Garcia, Alexander, Fostel, Jennifer, Morrison, Norman, Rocca-Serra, Philippe, Sansone, Susanna-Assunta

The current science landscape is rapidly evolving and it is increasingly driven by computational tasks. The deluge of data unleashed by omics-technologies, such as transcriptomics, proteomics and...

Chemical Effects in Biological Systems - Data Dictionary (CEBS-DD): A Compendium of Terms for the Capture and Integration of Biological Study Design Description, Conventional Phenotypes and 'Omics Data (2005)

Fostel, Jennifer, Choi, Danielle, Zwickl, Craig, Morrison, Norman, Rashid, Asif, Hasan, Atif, ...

A critical component in the design of the Chemical Effects in Biological Systems (CEBS) Knowledgebase is a strategy to capture toxicogenomics study protocols and the toxicity endpoint data (clinical...

Chemical Effects in Biological Systems--Data Dictionary (CEBS-DD): A Compendium of Terms for the Capture and Integration of Biological Study Design Description, Conventional Phenotypes, and 'Omics Data (2005)

Fostel, Jennifer, Choi, Danielle, Zwickl, Craig, Morrison, Norman, Rashid, Asif, Hasan, Atif, ...

A critical component in the design of the Chemical Effects in Biological Systems (CEBS) Knowledgebase is a strategy to capture toxicogenomics study protocols and the toxicity endpoint data (clinical...

Standardization Initiatives in the (eco)toxicogenomics Domain: A Review (2004)

Susanna Assunta Sansone, Norman Morrison, Philippe Rocca-Serra, Jennifer Fostel

The purpose of this document is to provide readers with a resource of different ongoing standardization efforts within the ‘omics’ (genomic, proteomics, metabolomics) and related communities,...

Isolation and characterization of a gene encoding DNA topoisomerase I in Drosophila melanogaster (1992)

Hsieh, Tao-shih, Brown, Sheryl D., Huang, Patti, Fostel, Jennifer

We synthesized a DNA probe specific for the gene encoding eucaryotic DNA topoisomerase I by the polymerase chain reaction. The sequences of the primers for this reaction were deduced from the regions...

Nucleotide sequence of the xanthine guanine phosphoribosyl transferase gene of E. coli (1983)

Richardson, Katherine Koren, Fostel, Jennifer, Skopek, Thomas R.

The nucleotide sequence of the gpt gene coding for the enzyme xanthine guanine phosphoribosyl transferase has been determined. The gene codes for a protein of molecular weight 16,950. The...

CEBS—Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data

Waters, Michael, Stasiewicz, Stanley, Alex Merrick, B., Tomer, Kenneth, Bushel, Pierre, Paules, Richard, ...

CEBS (Chemical Effects in Biological Systems) is an integrated public repository for toxicogenomics data, including the study design and timeline, clinical chemistry and histopathology findings and...

Standardization Initiatives in the (eco)toxicogenomics Domain: A Review

Sansone, Susanna Assunta, Morrison, Norman, Rocca-Serra, Philippe, Fostel, Jennifer

The purpose of this document is to provide readers with a resource of different ongoing standardization efforts within the ‘omics’ (genomic, proteomics, metabolomics) and related communities,...