Recognition of single-stranded RNA viruses by Toll-like receptor 7
Lund, Jennifer M., Alexopoulou, Lena, Sato, Ayuko, Karow, Margaret, Adams, Niels C., Gale, Nicholas W., ...
Viral infection of mammalian host results in the activation of innate immune responses. Toll-like receptors (TLRs) have been shown to mediate the recognition of many types of pathogens, including...
Recognition of single-stranded RNA viruses by Toll-like receptor 7
Lund, Jennifer M., Alexopoulou, Lena, Sato, Ayuko, Karow, Margaret, Adams, Niels C., Gale, Nicholas W., ...
Viral infection of mammalian host results in the activation of innate immune responses. Toll-like receptors (TLRs) have been shown to mediate the recognition of many types of pathogens, including...
Differentiation of regulatory Foxp3+ T cells in the thymic cortex
Liston, Adrian, Nutsch, Katherine M., Farr, Andrew G., Lund, Jennifer M., Rasmussen, Jeffery P., Koni, Pandelakis A., ...
Regulatory Foxp3+ T cells (TR) are indispensable for preventing autoimmune pathology in multiple organs and tissues. During thymic differentiation T cell receptor (TCR)–ligand interactions within a...
Tregs control the development of symptomatic West Nile virus infection in humans and mice
Lanteri, Marion C., O’Brien, Katie M., Purtha, Whitney E., Cameron, Mark J., Lund, Jennifer M., Owen, Rachel E., ...
West Nile virus (WNV) causes asymptomatic infection in most humans, but for undefined reasons, approximately 20% of immunocompetent individuals develop West Nile fever, a potentially debilitating...