Jennifer Wessel

An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension (2007)

Wen, Gen, Wessel, Jennifer, Zhou, Weidong, Ehret, Georg B., Rao, Fangwen, Stridsberg, Mats, ...

Granins regulate secretory vesicle formation in neuroendocrine cells and granin-derived peptides are co-released with neurotransmitters as modulatory signals at sympathetic sites. We report evidence...

Human genetic-epidemiologic association analysis via allelic composition and DNA sequence similarity methods applications to blood-based gene expression biomarkers of disease / (2006)

Wessel, Jennifer.

Thesis (Ph. D.)--University of California, San Diego and San Diego State University, 2006.

Human genetic-epidemiologic association analysis via allelic composition and DNA sequence similarity methods [electronic resource] : applications to blood-based gene expression biomarkers of disease / (2006)

Wessel, Jennifer.

The Human Genome Project, and related DNA sequence variation projects, has provided researchers with both the motivation and raw material for considering large-scale genetic association studies...

Generalized genomic distance based regression methodology for multilocus association analysis (0000)

Wessel, Jennifer

Generalized genomic distance based regression methodology for multilocus association analysis

Wessel, Jennifer

Large-scale, multilocus genetic association studies require powerful and appropriate statistical-analysis tools that are designed to relate genotype and haplotype information to phenotypes of...

Generalized Genomic Distance–Based Regression Methodology for Multilocus Association Analysis

Wessel, Jennifer, Schork, Nicholas J.

Large-scale, multilocus genetic association studies require powerful and appropriate statistical-analysis tools that are designed to relate genotype and haplotype information to phenotypes of...

Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk

Zhang, Lian, Rao, Fangwen, Zhang, Kuixing, Khandrika, Srikrishna, Das, Madhusudan, Vaingankar, Sucheta M., ...

GTP cyclohydrolase 1 (GCH1) is rate limiting in the provision of the cofactor tetrahydrobiopterin for biosynthesis of catecholamines and NO. We asked whether common genetic variation at GCH1 alters...