Jenny J. Fischer

Regulatory networks of gene expression in heart and skeletal muscle cells on the level of histone modifications and transcription factors (2008)

Fischer, Jenny J.

In this study the role of histone modifications and their potential interactions with four key cardiac transcription factors in the context of heart development and congenital heart diseases were...

Prediction of cardiac transcription networks based on molecular data and complex clinical phenotypes (2008)

Toenjes, Martje, Schueler, Markus, Hammer, Stefanie, Pape, Utz J., Fischer, Jenny J., Felix Berger, Felix, ...

We present an integrative approach combining sophisticated techniques to construct cardiac gene regulatory networks based on correlated gene expression and optimized prediction of transcription...

Combinatorial effects of four histone modifications in transcription and differentiation (2008)

Fischer, Jenny J., Toedling, Joern, Krueger, Tammo, Schueler, Markus, Huber, Wolfgang, Sperling, Silke

Nucleosomes are involved in DNA compaction and transcriptional regulation. Yet it is unclear whether histone modification marks are primary or secondary to transcription and whether they interact to...

Characterization of TBX20 in human hearts and its regulation by TFAP2 (2008)

Hammer, Stefanie, Toenjes, Martje, Lange, Martin, Fischer, Jenny J., Dunkel, Ilona, Mebus, Siegrun, ...

The T-box family of transcription factors has been shown to have major impact on human development and disease. In animal studies Tbx20 is essential for the development of the atrioventricular...

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex (2008)

Lange, Martin, Kaynak, Bogac, Forster, Ulrike B., Tönjes, Martje, Fischer, Jenny J., Grimm, Christina, ...

Chromatin remodeling and histone modifications facilitate access of transcription factors to DNA by promoting the unwinding and destabilization of histone–DNA interactions. We present DPF3, a new...

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex (2008)

Lange, Martin, Kaynak, Bogac, Forster, Ulrike B., Tönjes, Martje, Fischer, Jenny J., Grimm, Christina, ...

Chromatin remodeling and histone modifications facilitate access of transcription factors to DNA by promoting the unwinding and destabilization of histone–DNA interactions. We present DPF3, a new...

Ringo – an R/Bioconductor package for analyzing ChIP-chip readouts (2007)

Toedling, Joern, Skylar, Oleg, Krueger, Tammo, Fischer, Jenny J, Sperling, Silke, Huber, Wolfgang

No abstract available.

Ringo – an R/Bioconductor package for analyzing ChIP-chip readouts (2007)

Toedling, Joern, Skylar, Oleg, Krueger, Tammo, Fischer, Jenny J., Sperling, Silke, Huber, Wolfgang

Regulatory Networks of Gene Expression in Heart and Skeletal Muscle Cells on the Level of Histone Modifications and Transcription Factors (2007)

Fischer, Jenny J.

The overall aim of this study was to gain global insights into the role of histone modifications and their potential interactions with four key cardiac transcription factors in the context of heart...

Ringo – an R/Bioconductor package for analyzing ChIP-chip readouts

Toedling, Joern, Skylar, Oleg, Krueger, Tammo, Fischer, Jenny J, Sperling, Silke, Huber, Wolfgang

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex

Lange, Martin, Kaynak, Bogac, Forster, Ulrike B., Tönjes, Martje, Fischer, Jenny J., Grimm, Christina, ...

Chromatin remodeling and histone modifications facilitate access of transcription factors to DNA by promoting the unwinding and destabilization of histone–DNA interactions. We present DPF3, a new...