Jerome F. Strauss

PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women (2009)

Chen, Chen, Wickenheisser, Jessica, Ewens, Kathryn G., Ankener, Wendy, Legro, Richard S., Dunaif, Andrea, ...

Polycystic ovary syndrome (PCOS) is characterized by excessive theca cell androgen secretion, dependent upon LH, which acts through the intermediacy of 3′,5′-cyclic adenosine monophosphate...

Genetic and epigenetic mechanisms combine to control MMP1 expression and its association with preterm premature rupture of membranes (2008)

Wang, Hongyan, Ogawa, Masaki, Wood, Jennifer R., Bartolomei, Marisa S., Sammel, Mary D., Kusanovic, Juan Pedro, ...

Degradation of fibrillar collagens is believed to be involved in the rupture of the fetal membranes during normal parturition and when the membranes rupture prematurely. Matrix metalloproteinase 1...

Patterns of expression of sperm flagellar genes: early expression of genes encoding axonemal proteins during the spermatogenic cycle and shared features of promoters of genes encoding central apparatus proteins (2005)

Horowitz, Eran, Zhang, Zhibing, Jones, Brian H., Moss, Stuart B., Ho, Clement, Wood, Jennifer R., ...

Sperm are motile cells. Thus, a significant component of the spermatogenic cycle is devoted to the formation of flagellum, a process that must be coordinated to insure proper construction. To...

Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM) (2004)

Wang, Hongyan, Parry, Samuel, Macones, George, Sammel, Mary D., Ferrand, Pedro E., Kuivaniemi, Helena, ...

Matrix metalloproteinase 8 (MMP8), an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. We identified...

Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM) (2004)

Wang, Hongyan, Parry, Samuel, Macones, George, Sammel, Mary D., Ferrand, Pedro E., Kuivaniemi, Helena, ...

Matrix metalloproteinase 8 (MMP8), an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. We identified...

The CARD15 2936insC mutation and TLR4 896 A>G polymorphism in African Americans and risk of preterm premature rupture of membranes (PPROM) (2002)

Ferrand, Pedro E., Fujimoto, Toshio, Chennathukuzhi, Vargheese, Parry, Samuel, Macones, George A., Sammel, Mary, ...

Infection is believed to be a leading cause of preterm premature rupture of membranes (PPROM). The bacterial cell wall component, lipopolysaccharide (LPS), is thought to initiate tissue responses...

A polymorphism in the matrix metalloproteinase-9 promoter is associated with increased risk of preterm premature rupture of membranes in African Americans (2002)

Ferrand, Pedro E., Parry, Samuel, Sammel, Mary, Macones, George A., Kuivaniemi, Helena, Romero, Roberto, ...

Fetal membrane rupture is associated with increased expression of matrix metalloproteinase-9 (MMP-9) and matrix degradation. We have determined the functional significance of a variable number tandem...

T->A transversion 11 bp from a splice acceptor site in the human gene for steroidogenic acute regulatory protein causes congenital lipoid adrenal hyperplasia (1995)

Tee, Meng-Kian, Lin, Dong, Sugawara, Teruo, Holt, John A., Guiguen, Yann, Buckingham, Bruce, ...

Congenital lipoid adrenal hyperplasia (lipoid CAH) is the most severe form of CAH. Affected individuals can make no adrenal or gonadal steroids. All affected individuals are phenotypic females...

Pml Is Critical for Nd10 Formation and Recruits the Pml-Interacting Protein Daxx to This Nuclear Structure When Modified by Sumo-1

Ishov, Alexander M., Sotnikov, Alexey G., Negorev, Dmitri, Vladimirova, Olga V., Neff, Norma, Kamitani, Tetsu, ...

Nuclear domain 10 (ND10), also referred to as nuclear bodies, are discrete interchromosomal accumulations of several proteins including promyelocytic leukemia protein (PML) and Sp100. In this study,...

MEIG1 is essential for spermiogenesis in mice

Zhang, Zhibing, Shen, Xuening, Gude, David R., Wilkinson, Bonney M., Justice, Monica J., Flickinger, Charles J., ...

Spermatogenesis can be divided into three stages: spermatogonial mitosis, meiosis of spermatocytes, and spermiogenesis. During spermiogenesis, spermatids undergo dramatic morphological changes...