PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women (2009)
Chen, Chen, Wickenheisser, Jessica, Ewens, Kathryn G., Ankener, Wendy, Legro, Richard S., Dunaif, Andrea, ...
Polycystic ovary syndrome (PCOS) is characterized by excessive theca cell androgen secretion, dependent upon LH, which acts through the intermediacy of 3′,5′-cyclic adenosine monophosphate...
Wang, Hongyan, Ogawa, Masaki, Wood, Jennifer R., Bartolomei, Marisa S., Sammel, Mary D., Kusanovic, Juan Pedro, ...
Degradation of fibrillar collagens is believed to be involved in the rupture of the fetal membranes during normal parturition and when the membranes rupture prematurely. Matrix metalloproteinase 1...
Horowitz, Eran, Zhang, Zhibing, Jones, Brian H., Moss, Stuart B., Ho, Clement, Wood, Jennifer R., ...
Sperm are motile cells. Thus, a significant component of the spermatogenic cycle is devoted to the formation of flagellum, a process that must be coordinated to insure proper construction. To...
Horowitz, Eran, Zhang, Zhibing, Jones, Brian H., Moss, Stuart B., Ho, Clement, Wood, Jennifer R., ...
Wang, Hongyan, Parry, Samuel, Macones, George, Sammel, Mary D., Ferrand, Pedro E., Kuivaniemi, Helena, ...
Matrix metalloproteinase 8 (MMP8), an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. We identified...
Wang, Hongyan, Parry, Samuel, Macones, George, Sammel, Mary D., Ferrand, Pedro E., Kuivaniemi, Helena, ...
Matrix metalloproteinase 8 (MMP8), an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. We identified...
Ferrand, Pedro E., Fujimoto, Toshio, Chennathukuzhi, Vargheese, Parry, Samuel, Macones, George A., Sammel, Mary, ...
Infection is believed to be a leading cause of preterm premature rupture of membranes (PPROM). The bacterial cell wall component, lipopolysaccharide (LPS), is thought to initiate tissue responses...
Ferrand, Pedro E., Parry, Samuel, Sammel, Mary, Macones, George A., Kuivaniemi, Helena, Romero, Roberto, ...
Fetal membrane rupture is associated with increased expression of matrix metalloproteinase-9 (MMP-9) and matrix degradation. We have determined the functional significance of a variable number tandem...
Tee, Meng-Kian, Lin, Dong, Sugawara, Teruo, Holt, John A., Guiguen, Yann, Buckingham, Bruce, ...
Congenital lipoid adrenal hyperplasia (lipoid CAH) is the most severe form of CAH. Affected individuals can make no adrenal or gonadal steroids. All affected individuals are phenotypic females...
Ishov, Alexander M., Sotnikov, Alexey G., Negorev, Dmitri, Vladimirova, Olga V., Neff, Norma, Kamitani, Tetsu, ...
Nuclear domain 10 (ND10), also referred to as nuclear bodies, are discrete interchromosomal accumulations of several proteins including promyelocytic leukemia protein (PML) and Sp100. In this study,...
MEIG1 is essential for spermiogenesis in mice
Zhang, Zhibing, Shen, Xuening, Gude, David R., Wilkinson, Bonney M., Justice, Monica J., Flickinger, Charles J., ...
Spermatogenesis can be divided into three stages: spermatogonial mitosis, meiosis of spermatocytes, and spermiogenesis. During spermiogenesis, spermatids undergo dramatic morphological changes...