Smith, Ruben, Bacos, Karl, Fedele, Valentina, Soulet, Denis, Walz, Helena A., Obermüller, Stefanie, ...
Huntington's disease is a severe progressive neurodegenerative disorder caused by a CAG expansion in the IT15 gene, which encodes huntingtin. The disease primarily affects the neostriatum and...
Anisimov, Sergey V, Christophersen, Nicolaj S, Correia, Ana S, Li, Jia-Yi, Brundin, Patrik
Abstract Background Human stem cells are viewed as a possible source of neurons for a cell-based therapy of neurodegenerative disorders, such as Parkinson's disease. Several protocols that generate...
Anisimov, Sergey V, Christophersen, Nicolaj S, Correia, Ana S, Li, Jia-Yi, Brundin, Patrik
Abstract is not available
Abstract is not available
Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease. (2007)
Smith, Ruben, Klein, Pontus, Koc-Schmitz, Yeliz, Waldvogel, Henry J, Faull, Richard L M, Brundin, Patrik, ...
Abstract is not available
Restorative cell therapy for Parkinson's disease: A quest for the perfect cell. (2007)
Hall, Vanessa J, Li, Jia-Yi, Brundin, Patrik
Abstract is not available
From bench to bed: the potential of stem cells for the treatment of Parkinson's disease. (2007)
Morizane, Asuka, Li, Jia-Yi, Brundin, Patrik
Abstract is not available
Failure of transdifferentiation of adult hematopoietic stem cells into neurons. (2006)
Roybon, Laurent, Ma, Zhi, Asztely, Fredrik, Fosum, Anna, Jacobsen, Sten Eirik W, Brundin, Patrik, ...
Abstract is not available
Laminin {alpha}1 chain improves laminin {alpha}2 chain deficient peripheral neuropathy. (2006)
Gawlik, Kinga I, Li, Jia-Yi, Petersén, Asa, Durbeej, Madeleine
Abstract is not available
Cholinergic neuronal defect without cell loss in Huntington's disease. (2006)
Smith, Ruben, Chung, Hinfan, Rundquist, Sara, Colgan, Lesley, Englund, Elisabet, ...
Abstract is not available
Transplantation in Parkinson's disease: The future looks bright. (2006)
Paul, Gesine, Ahn, Young Hwan, Li, Jia-Yi, Brundin, Patrik
Abstract is not available.
Cholinergic neuronal defect without cell loss in Huntington's disease (2006)
Smith, Ruben, Chung, Hinfan, Rundquist, Sara, Colgan, Lesley, Englund, Elisabet, ...
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG-repeat expansion in the huntingtin (IT15) gene. The striatum is one of the regions most affected by neurodegeneration,...
Laminin {alpha}1 chain improves laminin {alpha}2 chain deficient peripheral neuropathy (2006)
Gawlik, Kinga I., Li, Jia-Yi, Petersén, Åsa, Durbeej, Madeleine
Absence of laminin α2 chain leads to a severe form of congenital muscular dystrophy (MDC1A) associated with peripheral neuropathy. Hence, future therapies should be aimed at alleviating both muscle...
Cholinergic neuronal defect without cell loss in Huntington's disease (2006)
Smith, Ruben, Chung, Hinfan, Rundquist, Sara, Colgan, Lesley, Englund, Elisabet, ...
Huntington's Disease (HD) is a neurodegenerative disorder caused by a CAG-repeat expansion in the huntingtin (IT15) gene. The striatum is one of the regions most affected by neurodegeneration,...
Laminin {alpha}1 chain improves laminin {alpha}2 chain deficient peripheral neuropathy (2006)
Gawlik, Kinga I., Li, Jia-Yi, Petersén, Åsa, Durbeej, Madeleine
Absence of laminin α2 chain leads to a severe form of congenital muscular dystrophy (MDC1A) associated with peripheral neuropathy. Hence, future therapies should be aimed at alleviating both muscle...
Björkqvist, Maria, Fex, Malin, Renström, Erik, Wierup, Nils, Petersén, Asa, Gil, Joana, ...
Abstract is not available
Smith, Ruben, Petersén, Asa, Bates, Gillian P, Brundin, Patrik, Li, Jia-Yi
Abstract is not available
Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice. (2005)
Mohapel, Paul, Araújo, Inês M, Popovic, Natalija, Li, Jia-Yi, Brundin, Patrik, ...
Abstract is not available
Roybon, Laurent, Brundin, Patrik, Li, Jia-Yi
Abstract is not available
Stem cell-based therapy for Parkinson's disease. (2005)
Correia, Ana Sofia, Anisimov, Sergey V, Li, Jia-Yi, Brundin, Patrik
Abstract is not available
Björkqvist, Maria, Fex, Malin, Renström, Erik, Wierup, Nils, Petersén, Åsa, Gil, Joana, ...
Diabetes frequently develops in Huntington's disease (HD) patients and in transgenic mouse models of HD such as the R6/2 mouse. The underlying mechanisms have not been clarified. Elucidating the...
Orexin loss in Huntington's disease (2005)
Petersén, Åsa, Gil, Joana, Björkqvist, Maria, Tanila, Heikki, Araújo, Inês M., ...
Huntington's disease (HD) is a devastating neurodegenerative disorder caused by an expanded CAG repeat in the gene encoding huntingtin, a protein of unknown function. Mutant huntingtin forms...
Stem cell therapy for Parkinson's disease: where do we stand? (2004)
Roybon, Laurent, Christophersen, Nicolaj S., Brundin, Patrik, Li, Jia-Yi
Abstract is not available
Orexin loss in Huntington's disease. (2004)
Petersén, Asa, Gil, Joana, Maat-Schieman, Marion Lc, Björkqvist, Maria, Tanila, Heikki, Araújo, Ines M, ...
Abstract is not available
Orexin loss in Huntington's disease (2004)
Petersén, Åsa, Gil, Joana, Maat-Schieman, Marion LC, Björkqvist, Maria, Tanila, Heikki, Araújo, Ines M, ...
Huntington's disease is a devastating neurodegenerative disorder caused by an expanded CAG repeat in the gene encoding huntingtin, a protein of unknown function. Mutant huntingtin forms intracellular...
Orexin loss in Huntington's disease (2004)
Petersén, Åsa, Gil, Joana, Maat-Schieman, Marion LC, Björkqvist, Maria, Tanila, Heikki, Araújo, Ines M, ...
Huntington's disease is a devastating neurodegenerative disorder caused by an expanded CAG repeat in the gene encoding huntingtin, a protein of unknown function. Mutant huntingtin forms intracellular...
Gradin, Kathryn A, Buus, Carsten L, Li, Jia-Yi, Frøbert, Ole, Simonsen, Ulf
The present study addressed the role of neuropeptide (NPY) Y2 receptors in neurogenic contraction of mesenteric resistance arteries from female spontaneously hypertensive rats (SHR). Arteries were...
Correia, Ana Sofia, Anisimov, Sergey V., Roybon, Laurent, Li, Jia-Yi, Brundin, Patrik
In the central nervous system, fibroblast growth factor (FGF)-20 has been reported to act preferentially on midbrain dopaminergic neurons. It also promotes the dopaminergic differentiation of stem...
Correia, Ana Sofia, Anisimov, Sergey V., Li, Jia-Yi, Brundin, Patrik
Human embryonic stem cells (hESCs) are a potential source of dopaminergic neurons for treatment of patients with Parkinson's disease (PD). Dopaminergic neurons can be derived from hESCs and display a...
Roybon, Laurent, Hjalt, Tord, Stott, Simon, Guillemot, Francois, Li, Jia-Yi, Brundin, Patrik
The specification and differentiation of dentate gyrus granule neurons in the hippocampus require temporally and spatially coordinated actions of both intrinsic and extrinsic molecules. The basic...