Jiajian Liu

Publication List Details

Period

1996 - 2008

Number

21

Co-Authors

Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors (2008)

Liu, Jiajian, Stormo, Gary D.

Motivation: Modeling and identifying the DNA-protein recognition code is one of the most challenging problems in computational biology. Several quantitative methods have been developed to model...

The cis-regulatory map of Shewanella genomes (2008)

Liu, Jiajian, Xu, Xing, Stormo, Gary D.

While hundreds of microbial genomes are sequenced, the challenge remains to define their cis-regulatory maps. Here, we present a comparative genomic analysis of the cis-regulatory map of Shewanella...

Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein (2005)

Liu, Jiajian, Stormo, Gary D

Abstract Background Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not be precisely...

Combining SELEX with quantitative assays to rapidly obtain accurate models of protein-DNA interactions (2005)

Liu, Jiajian, Stormo, Gary D.

Models for the specificity of DNA-binding transcription factors are often based on small amounts of qualitative data and therefore have limited accuracy. In this study we demonstrate a simple and...

Computational identification of the Spo0A-phosphate regulon that is essential for the cellular differentiation and development in Gram-positive spore-forming bacteria (2003)

Liu, Jiajian, Tan, Kai, Stormo, Gary D.

Spo0A‐phosphate is essential for the initiation of cellular differentiation and developmental processes in Gram‐positive spore‐forming bacteria. Here we combined comparative genomics...

A Molecular Switch Controlling Competence and Motility: Competence Regulatory Factors ComS, MecA, and ComK Control ςD-Dependent Gene Expression in Bacillus subtilis

Liu, Jiajian, Zuber, Peter

Bacillus subtilis, like many bacteria, will choose among several response pathways when encountering a stressful environment. Among the processes activated under growth-restricting conditions are...

Computational identification of the Spo0A-phosphate regulon that is essential for the cellular differentiation and development in Gram-positive spore-forming bacteria

Liu, Jiajian, Tan, Kai, Stormo, Gary D.

Spo0A-phosphate is essential for the initiation of cellular differentiation and developmental processes in Gram-positive spore-forming bacteria. Here we combined comparative genomics with analyses of...

Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling during adipogenesis.

Moldes, Marthe, Zuo, Ying, Morrison, Ron F, Silva, David, Park, Bae-Hang, Liu, Jiajian, ...

The Wnt/beta-catenin signalling pathway appears to operate to maintain the undifferentiated state of preadipocytes by inhibiting adipogenic gene expression. To define the mechanisms regulating...

Combining SELEX with quantitative assays to rapidly obtain accurate models of protein–DNA interactions

Liu, Jiajian, Stormo, Gary D.

Models for the specificity of DNA-binding transcription factors are often based on small amounts of qualitative data and therefore have limited accuracy. In this study we demonstrate a simple and...

Functional Interaction between Peroxisome Proliferator-Activated Receptor γ and β-Catenin†

Liu, Jiajian, Wang, Hong, Zuo, Ying, Farmer, Stephen R.

Studies have demonstrated cross talk between β-catenin and peroxisome proliferator-activated receptor γ (PPARγ) signaling pathways. Specifically, activation of PPARγ induces the proteasomal...

A Molecular Switch Controlling Competence and Motility: Competence Regulatory Factors ComS, MecA, and ComK Control ςD-Dependent Gene Expression in Bacillus subtilis

Liu, Jiajian, Zuber, Peter

Bacillus subtilis, like many bacteria, will choose among several response pathways when encountering a stressful environment. Among the processes activated under growth-restricting conditions are...

Computational identification of the Spo0A-phosphate regulon that is essential for the cellular differentiation and development in Gram-positive spore-forming bacteria

Liu, Jiajian, Tan, Kai, Stormo, Gary D.

Spo0A-phosphate is essential for the initiation of cellular differentiation and developmental processes in Gram-positive spore-forming bacteria. Here we combined comparative genomics with analyses of...

Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling during adipogenesis.

Moldes, Marthe, Zuo, Ying, Morrison, Ron F, Silva, David, Park, Bae-Hang, Liu, Jiajian, ...

The Wnt/beta-catenin signalling pathway appears to operate to maintain the undifferentiated state of preadipocytes by inhibiting adipogenic gene expression. To define the mechanisms regulating...

Combining SELEX with quantitative assays to rapidly obtain accurate models of protein–DNA interactions

Liu, Jiajian, Stormo, Gary D.

Models for the specificity of DNA-binding transcription factors are often based on small amounts of qualitative data and therefore have limited accuracy. In this study we demonstrate a simple and...

Functional Interaction between Peroxisome Proliferator-Activated Receptor γ and β-Catenin†

Liu, Jiajian, Wang, Hong, Zuo, Ying, Farmer, Stephen R.

Studies have demonstrated cross talk between β-catenin and peroxisome proliferator-activated receptor γ (PPARγ) signaling pathways. Specifically, activation of PPARγ induces the proteasomal...

The cis-regulatory map of Shewanella genomes

Liu, Jiajian, Xu, Xing, Stormo, Gary D.

While hundreds of microbial genomes are sequenced, the challenge remains to define their cis-regulatory maps. Here, we present a comparative genomic analysis of the cis-regulatory map of Shewanella...

Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors

Liu, Jiajian, Stormo, Gary D.

Motivation: Modeling and identifying the DNA-protein recognition code is one of the most challenging problems in computational biology. Several quantitative methods have been developed to model...