Robert Sisneros, Markus Glatter, On Langley, Jian Huang, Forrest Hoffman, David J. Erickson
doi:10.1088/1742-6596/125/1/012093 Time-varying multivariate visualization for understanding terrestrial biogeochemistry
Mining novel biomarkers for prognosis of gastric cancer with serum proteomics (2009)
Qiu, Fu-Ming, Yu, Jie-Kai, Chen, Yi-Ding, Jin, Qi-Feng, Sui, Mei-Hua, Huang, Jian
Abstract Background Although gastric caner (GC) remains the second cause of cancer-related death, useful biomarkers for prognosis are still unavailable. We present here the attempt of mining novel...
Testing the Box-Cox Parameter in an Integrated Process (2009)
Huang, Jian, Kobayashi, Masahito, McAleer, Michael
This paper analyses the constant elasticity of volatility (CEV) model suggested by [6]. The CEV model without mean reversion is shown to be the inverse Box-Cox transformation of integrated processes...
Consistent Group Selection in High-Dimensional Linear Regression (2009)
In regression problems where covariates can be naturally grouped, the group Lasso is an attractive method for variable selection, since it respects the grouping structure in the data. We study the...
Asymptotic Properties of Nonparametric Estimation Based on Partly Interval-Censored Data (2009)
Abstract: We study asymptotic properties of the nonparametric maximum likelihood estimator (NPMLE) of a distribution function based on partly interval-censored data in which the exact values of some...
40 PREDICTING B CELL EPITOPE RESIDUES WITH NETWORK TOPOLOGY BASED AMINO ACID INDICES (2009)
We evaluate the performance of six amino acid indices in B cell epitope residue prediction using the classical sliding window method on five data sets. Four of the indices: i.e. relative...
152 NEW AMINO ACID INDICES BASED ON RESIDUE NETWORK TOPOLOGY (2009)
Amino acid indices are useful tools in bioinformatics. With the appearance of novel theory and technology, and the rapid increase of experimental data, building new indices to cope with new or...
New Evaluation Criteria for the Convergence of Continuous Evolutionary Algorithms (2009)
Ying Lin, Student Member Ieee, Jian Huang, Jun Zhang (corresponding
Abstract—The first hitting time (FHT) plays an important role in convergence evaluation for evolutionary algorithms. However, the current criteria of the FHT are mostly under a hypothesis that...
Time-Varying Multivariate Visualization for Understanding Terrestrial (2009)
Robert Sisneros, Markus Glatter, On Langley, Jian Huang, Forrest Hoffman, David J
Abstract. Petascale computing has brought forth a transformational way of science. To the global effort on studying climate change, this shift has enabled not only tools more functional and more...
Visualizing Temporal Patterns in Large Multivariate Data using Textual Pattern Matching (2009)
Markus Glatter, Student Member, Jian Huang, Sean Ahern, Jamison Daniel, Aidong Lu
Abstract — Extracting and visualizing temporal patterns in large scientific data is an open problem in visualization research. First, there are few proven methods to flexibly and concisely define...
Abstract Remote Visualization by Browsing Image Based Databases with Logistical Networking (2009)
Jin Ding, Jian Huang, Micah Beck, Shaotao Liu, Terry Moore, Stephen Soltesz
The need to provide remote visualization of large datasets with adequate levels of quality and interactivity has become a major impediment to distributed collaboration in Computational Science....
Wesley Kendall, Markus Glatter, Jian Huang, Forrest Hoffman, David E. Bernholdt
The recent advances in high performance computing, storage and networking technologies have enabled fundamental changes in current climate research. While sharing datasets and results is already...
Abstract—Volumetric datasets with multiple variables on each voxel over multiple time steps are often complex, especially when considering the exponentially large attribute space formed by the...
Dynamic Visualization of Co-expression in Systems Genetics Data (2009)
Joshua New, Wesley Kendall, Jian Huang, Elissa Chesler
Abstract—Biologists hope to address grand scientific challenges by exploring the abundance of data made available through microarray analysis and other high-throughput techniques. However, the...
SCAD-penalized regression in high-dimensional partially linear models (2009)
We consider the problem of simultaneous variable selection and estimation in partially linear models with a divergent number of covariates in the linear part, under the assumption that the vector of...
Which preventive measures might protect health care workers from SARS? (2009)
Chen, Wei-Qing, Ling, Wen-Hua, Lu, Ci-Yong, Hao, Yuan-Tao, Lin, Zhong-Ning, Ling, Li, ...
Abstract Background Despite the use of a series of preventive measures, a high incidence of severe acute respiratory syndrome (SARS) was observed among health care workers (HCWs) during the SARS...
Qidong risk area, China (2009)
Xing-hua Huang, Lu-hong Sun, Dong-dong Lu, Yan Sun, Li-jie Ma, Xi-ran Zhang, ...
AIM: One of the characteristics of hepatocellular carcinoma (HCC) in Qidong area is the selective mutation resulting in a serine substitution at codon 249 of the p53 gene (1, 20), and it has been...
Jack M. Rogers, Jian Huang, William M. Smith, Raymond E. Ideker, Jack M. Rogers, Jian Huang, ...
Reprints: Information about reprints can be found online at
Regularized gene selection in cancer microarray meta-analysis (2009)
Abstract Background In cancer studies, it is common that multiple microarray experiments are conducted to measure the same clinical outcome and expressions of the same set of genes. An important goal...
A group bridge approach for variable selection (2009)
Huang, Jian, Ma, Shuange, Xie, Huiliang, Zhang, Cun-Hui
In multiple regression problems when covariates can be naturally grouped, it is important to carry out feature selection at the group and within-group individual variable levels simultaneously. The...
Huang, Jian, Chen, Keqiang, Huang, Jiaqiang, Gong, Wanghua, Dunlop, Nancy M., Howard, O.M.Zack, ...
The G protein-coupled formylpeptide receptor (FPR), known to mediate phagocytic leucocyte chemotaxis in reponse to bacterial- and host-derived agonists, was expressed by tumor cells in specimens of...
Shuangge Ma, Jian Huang, Open Access
© 2009 Ma and Huang; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License
PREDICTING B CELL EPITOPE RESIDUES WITH NETWORK TOPOLOGY BASED AMINO ACID INDICES (2008)
We evaluate the performance of six amino acid indices in B cell epitope residue prediction using the classical sliding window method on five data sets. Four of the indices: i.e. relative...
BIOINFORMATICS ORIGINAL PAPER (2008)
Gene Expression, Shuangge Ma, Jian Huang
Regularized ROC method for disease classification and biomarker selection with microarray data
Adaptively Represented Complete Distance Fields (2008)
Distance fields are an important volume representation. A high quality distance field facilitates accurate surface characterization and gradient estimation. However, due to Nyquist’s Law, no...
A Parallel Architecture for Motion Estimation and DCT Computation in MPEG-2 Encoder (2008)
Abstract. This paper presents a parallel architecture that can simultaneously perform block-matching motion estimation (ME) and discrete cosine transform (DCT). Because DCT and ME are both processed...
Collaborative Inductive Logic Programming for Path Planning (2008)
In distributed systems, learning does not necessarily involve the participation of agents directly in the inductive process itself. Instead, many systems frequently employ multiple instances of...
Self-Adaptive Configuration of Visualization Pipeline over Wide-Area Networks (2008)
Qishi Wu, Jinzhu Gao, Mengxia Zhu, Senior Member, Jian Huang, ...
Abstract—Next-generation scientific applications require the capability to visualize large archival data sets or on-going computer simulations of physical and other phenomena over wide-area network...
Visualization of Neuronal Fiber Connections (2008)
Nathaniel Fout, Jian Huang, Zhaohua Ding
from DT-MRI with Global Optimization Diffusion Tensor MRI (DT-MRI) provides valuable 3D data describing diffusion characteristics of water molecules in the human brain. From DT-MRI, it is hoped that...
Ultra-Scale Visualization: Research and Education (2008)
Kwan-liu Ma, Robert Ross, Jian Huang, Greg Humphreys, Kenneth Morel, John D. Owens, ...
Abstract. Understanding the science behind large-scale simulations and high-throughput experiments requires extracting meaning from data sets of hundreds of terabytes or more. Visualization is the...
Simulation is now a common means of research for material scientists. Often very large-scale models both in spatial and temporal dimensions are produced as a result. In those models, atoms are...
Jian Huang, Ziming Zhuang Zhuang, Jia Li Li, C. Lee, Giles Giles
Introduction and related work Characterizing network level collaboration Collaboration at the community level Collaboration between individuals Models and experiments
The sparsity and bias of the Lasso selection in high-dimensional linear regression (2008)
Meinshausen and Buhlmann [Ann. Statist. 34 (2006) 1436--1462] showed that, for neighborhood selection in Gaussian graphical models, under a neighborhood stability condition, the LASSO is consistent,...
Huang, Jian, Di, Pei, Fukuda, Toshio, 福田, 敏男, Matsuno, Takayuki
To obtain a secured mating of electric connectors is one of the most important steps in a robotic wiring harness assembly system. Although there are plentiful results about complex peg-in-hole...
Asymptotic properties of bridge estimators in sparse high-dimensional regression models (2008)
Huang, Jian, Horowitz, Joel L., Ma, Shuangge
We study the asymptotic properties of bridge estimators in sparse, high-dimensional, linear regression models when the number of covariates may increase to infinity with the sample size. We are...
Abstract Remote Visualization by Browsing Image Based Databases with Logistical Networking (2008)
Jin Ding, Jian Huang, Micah Beck, Shaotao Liu, Terry Moore, Stephen Soltesz
The need to provide remote visualization of large datasets with adequate levels of quality and interactivity has become a major impediment to distributed collaboration in Computational Science....
Basic Study on Sensory Aspects of a Master/Slave System for Force Telecommunication * (2008)
Masayuki Hara, Young-mi Jung, Jian Huang, Tetsuro Yabuta
Abstract – The advancement of multimedia services including audio/visual media has been rapid. The applications of cellular phones, in particular, have increased by using these technologies. In...
Collaborative Inductive Logic Programming for Path Planning (2008)
In distributed systems, learning does not necessarily involve the participation of agents directly in the inductive process itself. Instead, many systems frequently employ multiple instances of...
The Spectral Density Estimation of Stationary Time Series with Missing Data (2008)
Abstract The spectral estimation of unevenly sampled data has been widely investigated in astronomical and medical areas. However the investigations are usually carried out in the context of...
A Hidden Environment Model for Constructing Indoor Radio Maps (2008)
Zhe Xiang, Hangjin Zhang, Jian Huang, Song Song, Kevin C. Almeroth
Constructing indoor radio maps plays an important role in many services and applications such as wireless base station planning. In this paper, we propose a hybrid approach to constructing indoor...
Marginal mean models of temporal processes in event time data analysis are gaining more attention for its milder assumptions than the traditional intensity models. Recent work of fully functional...
Compiler-Assisted Sub-Block Reuse (2008)
The fact that instructions in programs often produce repetitive results has motivated researchers to explore various alternatives to exploit this value locality, such as value prediction and value...
Huang, Jian, Fukuda, Toshio, 福田, 敏男, Matsuno, Takayuki
Mating a pair of electric connectors is one of the most important steps in a robotic wiring harness assembly system. A class of piecewise linear force models is proposed to describe both the...
Nonequilibrium transport in mesoscopic multi-terminal SNS Josephson junctions (2008)
Crosser, M. S., Huang, Jian, Pierre, F., Virtanen, Pauli, Heikkilä, Tero T., Wilhelm, F. K., ...
We report the results of several nonequilibrium experiments performed on superconducting/normal/superconducting (S/N/S) Josephson junctions containing either one or two extra terminals that connect...
Concurrent Viewing of Multiple Attribute-Specific Subspaces (2008)
Robert Sisneros, C. Ryan Johnson, Jian Huang
In this work we present a point classification algorithm for multi-variate data. Our method is based on the concept of attribute subspaces, which are derived from a set of user specified attribute...
The Iterated Lasso for High-Dimensional Logistic Regression (2008)
Jian Huang, Shuange Ma, Cun-hui Zhang
We consider an iterated Lasso approach for variable selection and estimation in sparse, high-dimensional logistic regression models. In this approach, we use the Lasso (Tibshirani 1996) to obtain an...
Penalized feature selection and classification in bioinformatics (2008)
In bioinformatics studies, supervised classification with high-dimensional input variables is frequently encountered. Examples routinely arise in genomic, epigenetic and proteomic studies. Feature...
Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy (2008)
Li, Xiaoxian, Lewis, Michael T., Huang, Jian, Gutierrez, Carolina, Osborne, C. Kent, Wu, Meng-Fen, ...
Background Tumorigenic breast cancer cells that express high levels of CD44 and low or undetectable levels of CD24 (CD44>/CD24>/low) may be resistant to chemotherapy and therefore responsible for...
Disappearance of the metal-like behavior in GaAs two-dimensional holes below 30 mK (2007)
Huang, Jian, Xia, J. S., Tsui, D. C., Pfeiffer, L. N., West, K. W.
The zero-field temperature-dependence of the resistivity of two-dimensional holes are observed to exhibit two qualitatively different characteristics for a fixed carrier density for which only the...
Compiler-Assisted Sub-Block Reuse (2007)
The fact that instructions in programs often produce repetitive results has motivated researchers to explore various alternatives to exploit this value locality, such as value prediction and value...
Page-Mapping Techniques to Reduce Cache Conflicts on CC-NUMA Multiprocessors (2007)
Zhiyuan Li, Jian Huang, Guohua Jin
Page-coloring and bin-hopping are two well-known page mapping schemes for reducing cache conflicts. Previous work found bin-hopping to have 4% less cache miss rate than page-coloring on uniprocessor...
Page-Mapping Techniques for CC-NUMA Multiprocessors (2007)
Jian Huang, Guohua Jin, Zhiyuan Li
This paper extends previous page-mapping schemes to the more recent Cache-Coherent Non-Uniform Memory Access (CC-NUMA) multiprocessors. These extensions maintain the program's data-task...
Asymptotic Properties of Nonparametric Estimation Based on Partly Interval-Censored Data (2007)
: We study asymptotic properties of the nonparametric maximum likelihood estimator (NPMLE) of a distribution function based on partly interval-censored data in which the exact values of some failure...
Abstract An Accurate Method for Voxelizing Polygon Meshes (2007)
Jian Huang, Roni Yagel, Yair Kurzion
The process of generating discrete surfaces in a volumetric representation, termed voxelization, is confronted with topological considerations as well as accuracy and efficiency requirements. We...
Robust smooth segmentation approach for array CGH data analysis (2007)
Huang, Jian, Gusnanto, Arief, O'Sullivan, Kathleen, Staaf, Johan, Borg, Åke, Pawitan, Yudi
Motivation: Array comparative genomic hybridization (aCGH) provides a genome-wide technique to screen for copy number alteration. The existing segmentation approaches for analyzing aCGH data are...
Asymptotic oracle properties of SCAD-penalized least squares estimators (2007)
We study the asymptotic properties of the SCAD-penalized least squares estimator in sparse, high-dimensional, linear regression models when the number of covariates may increase with the sample size....
Estimation of the mean function with panel count data using monotone polynomial splines (2007)
Lu, Minggen, Zhang, Ying, Huang, Jian
We study nonparametric likelihood-based estimators of the mean function of counting processes with panel count data using monotone polynomial splines. The generalized Rosen algorithm, proposed by...
Huang, Jian, Zhang, Yun-Li, Teng, Xiao-Mei, Lin, Yun, Zheng, Da-Li, Yang, Peng-Yuan, ...
Abstract Background Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. SFRP1 (the secreted frizzled-related protein 1), a putative tumor suppressor gene mapped onto...
Huang, Jian, Hao, Pei, Zhang, Yun-Li, Deng, Fu-Xing, Deng, Qing, Hong, Yi, ...
Abstract Background The liver is the largest human internal organ – it is composed of multiple cell types and plays a vital role in fulfilling the body's metabolic needs and maintaining...
Use of external CFRP prestressing in Hewei bridge in China (2007)
Huang, Jian, Xia, Wengjun, Zhang, Yigui, Zhang, Rui, Peng, Wang, Ding, Hanshan
This paper was transferred from the original CD ROM created for this conference. The material on the CD ROM was published using Adobe Acrobat technology. The original CD ROM was produced by Document...
Use of external CFRP prestressing in Hewei bridge in China (2007)
Huang, Jian, Xia, Wengjun, Zhang, Yigui, Zhang, Rui, Peng, Wang, Ding, Hanshan
This paper was transferred from the original CD ROM created for this conference. The material on the CD ROM was published using Adobe Acrobat technology. The original CD ROM was produced by Document...
Additive risk survival model with microarray data (2007)
Abstract Background Microarray techniques survey gene expressions on a global scale. Extensive biomedical studies have been designed to discover subsets of genes that are associated with survival...
Identification and characterization of OGG1 mutations in patients with Alzheimer's disease (2007)
Mao, Guogen, Pan, Xiaoyu, Zhu, Bei-Bei, Zhang, Yanbin, Yuan, Fenghua, Huang, Jian, ...
Patients with Alzheimer's disease (AD) exhibit higher levels of 8-oxo-guanine (8-oxoG) DNA lesions in their brain, suggesting a reduced or defective 8-oxoG repair. To test this hypothesis, this study...
Graduation date: 2007
Graduation date: 2007
Up-regulation of DLK1 as an imprinted gene could contribute to human hepatocellular carcinoma (2007)
Huang, Jian, Zhang, Xin, Zhang, Min, Zhu, Jing-De, Zhang, Yun-Li, Lin, Yun, ...
Dysregulation of a genomic imprinting gene can contribute to carcinogenesis. Here, delta-like 1 homolog (Drosophila) (DLK1), a paternally expressed gene, was found to be significantly up-regulated in...
Song, Xiao, Ma, Shuangge, Huang, Jian, Zhou, Xiao-Hua
The nonparametric transformation model makes no parametric assumptions on the forms of the transformation function and the error distribution. This model is appealing in its flexibility for modeling...
Supervised group Lasso with applications to microarray data analysis (2007)
Ma, Shuangge, Song, Xiao, Huang, Jian
Abstract Background A tremendous amount of efforts have been devoted to identifying genes for diagnosis and prognosis of diseases using microarray gene expression data. It has been demonstrated that...
Robust smooth segmentation approach for array CGH data analysis. (2007)
Huang, Jian, Gusnanto, Arief, O'sullivan, Kathleen, Staaf, Johan, Borg, Ake, Pawitan, Yudi
Abstract is not available
Combining Clinical and Genomic Covariates via Cov-TGDR (2007)
Clinical covariates such as age, gender, tumor grade, and smoking history have been extensively used in prediction of disease occurrence and progression. On the other hand, genomic biomarkers...
Thesis (M.S.)--Oregon State University, 2007.
Combining Clinical and Genomic Covariates via Cov-TGDR (2007)
Clinical covariates such as age, gender, tumor grade, and smoking history have been extensively used in prediction of disease occurrence and progression. On the other hand, genomic biomarkers...
Robust smooth segmentation approach for array CGH data (2007)
Jian Huang, Arief Gusnanto, Johan Staaf, Yudi Pawitan, Prof Thomas Lengauer
analysis
A Group Bridge Approach for Variable Selection (2007)
Jian Huang, Shuangge Ma, Huiliang Xie, Cun-hui Zhang
In multiple regression problems when covariates can be naturally grouped, it is important to carry out feature selection at the group and within-group individual variable levels simultaneously. The...
Generative Models for Name Disambiguation (2007)
Yang Song, Jian Huang, Isaac G. Councill, Jia Li, C. Lee Giles
Name ambiguity is a special case of identity uncertainty where one person can be referenced by multiple name variations in different situations or evenshare the same name with other people. In this...
Supervised group Lasso with applications to microarray data analysis. BMC Bioinformatics 8:60 (2007)
Shuangge Ma, Shuangge Ma, Xiao Song, Xiao Song, Jian Huang, Jian Huang
Supervised group Lasso with applications to microarray data analysis
BMC Bioinformatics Methodology article Additive risk survival model with microarray data (2007)
Background: Microarray techniques survey gene expressions on a global scale. Extensive biomedical studies have been designed to discover subsets of genes that are associated with survival risks for...
Efficient Multiclass Boosting Classification with Active Learning (2007)
Jian Huang, Seyda Ertekin, Yang Song, Hongyuan Zha, C. Lee Giles
We propose a novel multiclass classification algorithm Gentle Adaptive Multiclass Boosting Learning (GAMBLE). The algorithm naturally extends the two class Gentle AdaBoost algorithm to multiclass...
Minggen Lu, Ying Zhang, Jian Huang
monotone polynomial splines
Formaldehyde-based adhesives such as urea-formaldehyde (UF) and phenol-formaldehyde (PF) adhesives dominate the current wood adhesive market. However, these adhesives are derived from petrochemicals...
Department of Statistics and Actuarial Science, (2007)
1 Abstract. Deletions and amplifications of the human genomic DNA copy number are the cause of numerous diseases such as various forms of cancer. Therefore, the detection of DNA copy number...
Clustering threshold gradient descent regularization: with applications to microarray studies (2007)
Motivation: An important goal of microarray studies is to discover genes that are associated with clinical outcomes, such as disease status and patient survival. While a typical experiment surveys...
Song, Xiao, Ma, Shuangge, Huang, Jian, Zhou, Xiao-Hua
The nonparametric transformation model makes no parametric assumptions on the forms of the transformation function and the error distribution. This model is appealing in its flexibility for modeling...
Song, Xiao, Ma, Shuangge, Huang, Jian, Zhou, Xiao-Hua
The nonparametric transformation model for survival time that makes no parametric assumptions on both the transformation function and the error is appealing in its flexibility. The nonparametric...
Song, Xiao, Ma, Shuangge, Huang, Jian, Zhou, Xiao-Hua
The nonparametric transformation model for survival time that makes no parametric assumptions on both the transformation function and the error is appealing in its flexibility. The nonparametric...
Song, Xiao, Ma, Shuangge, Huang, Jian, Zhou, Xiao-Hua
The nonparametric transformation model for survival time that makes no parametric assumptions on both the transformation function and the error is appealing in its flexibility. The nonparametric...
Song, Xiao, Ma, Shuangge, Huang, Jian, Zhou, Xiao-Hua
The nonparametric transformation model for survival time that makes no parametric assumptions on both the transformation function and the error is appealing in its flexibility. The nonparametric...
MIMOX: a web tool for phage display based epitope mapping (2006)
Huang, Jian, Gutteridge, Alex, Honda, Wataru, Kanehisa, Minoru
Abstract Background Phage display is widely used in basic research such as the exploration of protein-protein interaction sites and networks, and applied research such as the development of new...
Interaction effects in the transport of two-dimensional holes in GaAs (2006)
Huang, Jian, Novikov, D. S., Tsui, D. C., Pfeiffer, L. N., West, K. W.
The power-law increase of the conductivity with temperature in the nominally insulating regime, recently reported for the dilute two-dimensional holes [cond-mat/0603053], is found to systematically...
Huang, Jian, Wu, Lijun, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Oridonin, an active component isolated from Rabdosia rubescences, has been reported to have antitumor effects. In this study, we compared the signal transduction pathways between TNFalpha-and...
Huang, Jian, Wu, Lijun, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
We investigated the mechanism of the pan-caspase inhibitor z-VAD-fmk's augmentation of TNFalpha-induced L929 cell death and found this mechanism differs from that of TNFalpha-induced L929 cell death....
Regularized binormal ROC method in disease classification using microarray data (2006)
Ma, Shuangge, Song, Xiao, Huang, Jian
Abstract Background An important application of microarrays is to discover genomic biomarkers, among tens of thousands of genes assayed, for disease diagnosis and prognosis. Thus it is of interest to...
CED: a conformational epitope database (2006)
Abstract Background Antigen epitopes provide valuable information useful for disease prevention, diagnosis, and treatment. Recently, more and more databases focusing on different types of epitopes...
Non-activated transport of strongly interacting two-dimensional holes in GaAs (2006)
Huang, Jian, Novikov, D. S., Tsui, D. C., Pfeiffer, L. N., West, K. W.
We report on the transport measurements of two-dimensional holes in GaAs field effect transistors with record low densities down to 7*10^8 cm^{-2}. Remarkably, such a dilute system (with Fermi...
Asymmetric [4+3] cycloadditions via epoxidation of allenamides / (2006)
Appendices : leaves 171-206.
Theories of imaging electrons in nanostructures / (2006)
Thesis (Ph. D., Dept. of Physics)--Harvard University, 2006.
Far-from-cutoff conditions in cylindrical dieletric three-layer waveguide / (2006)
"Mémoire présenté en vue de l'obtention du diplôme de maîtrise ès sciences appliquées (génie physique)"
Efficient name disambiguation for large-scale databases (2006)
Abstract. Name disambiguation can occur when one is seeking a list of publications of an author who has used different name variations and when there are multiple other authors with the same name. We...
Adaptive Lasso for sparse highdimensional regression (2006)
Jian Huang, Shuangge Ma, Cun-hui Zhang
Summary. We study the asymptotic properties of adaptive LASSO estimators in sparse, high-dimensional, linear regression models when the number of covariates may increase with the sample size. We...
SCAD-Penalized Regression in High-Dimensional Partially Linear Models (2006)
Summary. We consider the problem of simultaneous variable selection and estimation in partially linear models with a divergent number of covariates in the linear part, under the assumption that the...
Adaptive Lasso for sparse highdimensional regression (2006)
Jian Huang, Shuangge Ma, Cun-hui Zhang
Summary. We study the asymptotic properties of the adaptive Lasso estimators in sparse, high-dimensional, linear regression models when the number of covariates may increase with the sample size. We...
Asymptotic properties of bridge estimators in sparse high-dimensional regression models (2006)
Jian Huang, Joel L. Horowitz, Shuangge Ma
Summary. We study the asymptotic properties of bridge estimators in sparse, high-dimensional, linear regression models when the number of covariates may increase to infinity with the sample size. We...
Boosting the Feature Space: Text Classification for Unstructured Data on the Web (2006)
Yang Song, Ding Zhou, Jian Huang, Isaac G. Councill, Hongyuan Zha, C. Lee Giles
The issue of seeking efficient and effective methods for classifying unstructured text in large document corpora has received much attention in recent years. Traditional document representation like...
Asymptotic properties of bridge estimators in sparse high-dimensional regression models (2006)
Jian Huang, Joel L. Horowitz, Shuangge Ma
Summary. We study the asymptotic properties of bridge estimators in sparse, high-dimensional, linear regression models when the number of covariates may increase to infinity with the sample size. We...
Discriminant analysis algorithms for face recognition / (2006)
Thesis (Ph.D.)--Hong Kong Baptist University, 2006.
BMC Bioinformatics BioMed Central (2006)
Jian Huang, Alex Gutteridge, Wataru Honda, Minoru Kanehisa, Open Access
Software MIMOX: a web tool for phage display based epitope mapping
Song, Xiao, Ma, Shuangge, Huang, Jian, Zhou, Xiao-Hua
The nonparametric transformation model makes no parametric assumptions on the forms of the transformation function and the error distribution. This model is appealing in its flexibility for modeling...
Abstract Dendritic cells (DCs) are professional antigen-presenting cells that are integral to the induction of primary, antigen-specific T cell responses. In the cancer setting, DCs mediate...
Abstract Dendritic cells (DCs) are professional antigen-presenting cells that are integral to the induction of primary, antigen-specific T cell responses. In the cancer setting, DCs mediate...
Walls, Jamie D., Huang, Jian, Westervelt, Robert M., Heller, Eric J.
In order to model the phase-coherent scattering of electrons in two-dimensional electron gases in the presence of Rashba spin-orbit coupling, a general partial-wave expansion is developed for...
Wan-Feng Guo, Ru-Xian Lin, Jian Huang, Zhe Zhou, Jing Yang, Guo-Zheng Guo, ...
Guo, W-F., Lin, R-X., Huang, J., Zhou, Z., Yang, J., Guo, G-Z. and Wang, S-Q. Identification of Differentially Expressed Genes Contributing to Radioresistance in Lung Cancer Cells using Microarray...
A robust two-way semi-linear model for normalization of cDNA microarray data (2005)
Wang, Deli, Huang, Jian, Xie, Hehuang, Manzella, Liliana, Soares, Marcelo
Abstract Background Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative expression...
Imaging a Single-Electron Quantum Dot (2005)
Fallahi, Parisa, Bleszynski, Ania C., Westervelt, Robert M., Huang, Jian, Walls, Jamie D., Heller, Eric J., ...
Images of a single-electron quantum dot were obtained in the Coulomb blockade regime at liquid He temperatures using a cooled scanning probe microscope (SPM). The charged SPM tip shifts the lowest...
Thesis (M.Sc.) - Department of Chemistry - Simon Fraser University
BMC Bioinformatics Methodology article (2005)
Shuangge Ma, Xiao Song, Jian Huang, Biomed Central
Regularized binormal ROC method in disease classification using microarray data
Regularized ROC Estimation: With Applications to Disease Classification Using Microarray Data (2005)
Summary Microarrays capable of monitoring gene expression on a large scale are becoming a routing tool in biomedical research. An important application of microarrays is to discover genomic...
Threshold Gradient Descent Regularization in the Additive Risk Model with (2005)
High-dimensional Covariates, Shuangge Ma, Jian Huang
Summary An additive risk model is a useful alternative to the Cox model (Cox, 1972) and may be adopted when the absolute effects, instead of the relative effects, of multiple predictors on the hazard...
LASSO method for additive risk models with high dimensional covariates (2005)
Summary. The additive risk model is a useful alternative to the proportional hazards model. It postulates that the hazard function is the sum of the baseline hazard function and the regression...
A two-way semilinear model for normalization and analysis of cDNA microarray data (2005)
Jian Huang, Hsun-chih Kuo, Irina Koroleva, Cun-hui Zhang, Marcelo Bento Soares
Microarray analysis is a technology for monitoring gene expression levels on a large scale and has been widely used in functional genomics. A challenging issue in the analysis of microarray data is...
Asymptotic Analysis of a Two-Way Semiparametric Regression Model for Microarray Data (2005)
statistics
Least Absolute Deviations Estimation for the Accelerated Failure Time Model (2005)
Jian Huang, Shuangge Ma, Huiliang Xie
Summary The accelerated failure time (AFT) model assumes a linear relationship between the event time and the covariates. We propose a robust weighted least-absolute-deviations (LAD) method for...
Jian Huang, Shuangge Ma, Huiliang Xie
Summary The need for analyzing failure time data with high-dimensional covariates arises in investigating the relationship between a censored survival outcome and microarray gene expression profiles....
Jian Huang, Deli Wang, Cun-hui Zhang
1 ABSTRACT A basic question in analyzing cDNA microarray data is normalization. The purpose of normalization is to remove systematic bias in the observed expression values by establishing a...
A two-way semilinear model for normalization and analysis of cDNA microarray data (2005)
Jian Huang, Deli Wang, Cun-hui Zhang
ABSTRACT A basic question in analyzing cDNA microarray data is normalization, the purpose of which is to remove systematic bias in the observed expression values by establishing a normalization curve...
Motivation: An important application of microarrays is to discover genomic biomarkers, among tens of thousands of genes assayed, for disease classification. Thus there is a need for developing...
Chai, Bob, Huang, Jian, Cairns, Bradley R., Laurent, Brehon C.
The failure of cells to repair damaged DNA can result in genomic instability and cancer. To efficiently repair chromosomal DNA lesions, the repair machinery must gain access to the damaged DNA in the...
Motivation: An important application of microarrays is to discover genomic biomarkers, among tens of thousands of genes assayed, for disease classification. Thus there is a need for developing...
Hannover, Universiẗat, Diss., 2004.
Modellierung verdeckter T-Stossverbindungen mittels MAG-Schweissverfahren / (2004)
Zugl.: Hannover, Univ., Diss., 2004.
Face Recognition Using Local and Global Features (2004)
Jian Huang, Pong C. Yuen, J. H. Lai, Chun-hung Li
The combining classifier approach has proved to be a proper way for improving recognition performance in the last two decades. This paper proposes to combine local and global facial features for face...
Active Logistical State Management in the GridSolve/L (2004)
Micah Beck, Jack Dongarra, Jian Huang, Terry Moore, James S. Plank
More than two decades of exponential growth in the supply of the basic computing resources, rapid progress in the deployment of high performance networks, and escalating requirements for distributed
Warm and cold deviations from the annual sea surface temperature climate in the eastern tropical Pacific have a wide significance. Numerous reports have examined connections between these so-called...
Face Recognition Using Local and Global Features (2004)
Chun-hung Li, J. H. Lai, Pong C. Yuen, Jian Huang
The combining classifier approach has proved to be a proper way for improving recognition performance in the last two decades. This paper proposes to combine local and global facial features for face...
Face Recognition Using Local and Global Features (2004)
Jian Huang, Pong C. Yuen, J. H. Lai, Chun-hung Li
The combining classifier approach has proved to be a proper way for improving recognition performance in the last two decades. This paper proposes to combine local and global facial features for face...
Genome-wide linkage analysis of blood pressure under locus heterogeneity (2003)
Yang, Xinqun, Wang, Kai, Huang, Jian, Vieland, Veronica J
Abstract We describe a method for mapping quantitative trait loci that allows for locus heterogeneity. A genome-wide linkage analysis of blood pressure was performed using sib-pair data from the...
The exon context and distribution of Euascomycetes rRNA spliceosomal introns (2003)
Bhattacharya, Debashish, Simon, Dawn, Huang, Jian, Cannone, Jamie J, Gutell, Robin R
Abstract Background We have studied spliceosomal introns in the ribosomal (r)RNA of fungi to discover the forces that guide their insertion and fixation. Results Comparative analyses of flanking...
Robert Ward, Jian Huang, Peter Cummings, Sharad Anant Gupta
To the Graduate Council: I am submitting herewith a thesis written by Sharad Anant Gupta entitled “3D visualization modules for chemical engineering – A web-based approach using Java and OpenGL...
Visibility Culling Using Plenoptic Opacity Functions for Large Volume Visualization (2003)
Jinzhu Gao, Jian Huang, Han-Wei Shen, James Arthur Kohl
Visibility culling has the potential to accelerate large data visualization in significant ways. Unfortunately, existing algorithms do not scale well when parallelized, and require full...
A.: Visibility Culling Using Plenoptic Opacity Functions for Large Data Visualization (2003)
Visibility culling has the potential to accelerate large data visualization in significant ways. Unfortunately, existing algorithms do not scale well when parallelized, and require full...
Understanding Gigabit Ethernet Performance on (2003)
Jian Huang, Sun Blueprints Online—february
particular, and without limitation, these intellectual property rights may include one or more of the U.S. patents listed at
Observation of a controllable PI-junction in a 3-terminal Josephson device (2002)
Huang, Jian, Pierre, F., Heikkila, Tero T., Wilhelm, Frank K., Birge, Norman O.
Recently Baselmans et al. [Nature, 397, 43 (1999)] showed that the direction of the supercurrent in a superconductor/normal/superconductor Josephson junction can be reversed by applying,...
OPNET Simulation Of A Multi-hop Self-organizing Wireless Sensor Network (2002)
Yan Huang, Jian Huang, Lance Hester, Anthony Allen, Oleg Andric, Priscilla Chen
In this paper we simulate a multi-hop self-organizing wireless sensor network. The purpose of the simulation is to investigate, quantitatively, the performance of our self-organizing network design....
Non-equilibrium proximity effect in a SNS junction / (2001)
Thesis (Ph. D.)--Michigan State University. Dept. of Physics, 2001.
Improving processor performance through compiler-assisted block reuse / (2000)
Thesis (Ph. D.)--University of Minnesota, 2000.
is built on top of the SimpleScalar tool set [1] in an effort to evaluate the performance of the superthreaded architecture [4, 5], and to explore the different design alternatives. Our compiler can...
Fastsplats: Optimized splatting on rectilinear grids (2000)
Jian Huang, Klaus Mueller, Naeem Shareef, Roger Crawfis
Splatting is widely applied in many areas, including volume, point-based, and image-based rendering. Improvements to splatting, such as eliminating popping and color bleeding, occlusion-based...
Improving Processor Performance through Compiler Assisted Block Reuse (2000)
Superscalar microprocessors currently power the majority of computing machines. These proces-sors are capable of executing multiple independent instructions in each clock cycle by exploiting the...
Exploring Sub-Block Value Reuse for Superscalar Processors (2000)
Jian Huang, Sun Microsystems, David J. Lilja
The performance potential of a value reuse mechanism depends on its reuse detection time, the number of reuse opportunities, and the amount of work saved by skipping each reuse unit. Since larger...
Improving Processor Performance Through Compiler-Assisted Block Reuse (2000)
Jian Huang, David Lilja Adviser
Superscalar microprocessors currently power the majority of computing machines. These processors are capable of executing multiple independent instructions in each clock cycle by exploiting the...
Extending Value Reuse to Basic Blocks with Compiler Support (2000)
Speculative execution and instruction reuse are two important strategies that have been investigated for improving processor performance. Value prediction at the instruction level has been introduced...
Improving Processor Performance through Compiler-Assisted Block Reuse (2000)
Superscalar microprocessors currently power the majority of computing machines. These processors are capable of executing multiple independent instructions in each clock cycle by exploiting the...
A practical evaluation of popular volume rendering algorithms (2000)
Michael Meißner, Jian Huang, Dirk Bartz, Klaus Mueller, Roger Crawfis
This paper evaluates and compares four volume rendering algorithms that have become rather popular for rendering datasets described on uniform rectilinear grids: raycasting, splatting, shear-warp,...
A practical evaluation of popular volume rendering algorithms (2000)
Michael Meißner, Jian Huang, Dirk Bartz, Klaus Mueller, Roger Crawfis
This paper evaluates and compares four volume rendering algorithms that have become rather popular for rendering datasets described on uniform rectilinear grids: raycasting, splatting, shear-warp,...
Fastsplats: Optimized splatting on rectilinear grids (2000)
Jian Huang, Klaus Mueller, Naeem Shareef, Roger Crawfis
Splatting is widely applied in many areas, including volume, point-based, and image-based rendering. Improvements to splatting, such as eliminating popping and color bleeding, occlusion-based...
Exploring Sub-Block Value Reuse for Superscalar Processors (2000)
The performance potential of a value reuse mechanism depends on its reuse detection time, the number of reuse opportunities, and the amount of work saved by skipping each reuse unit. Since larger...
A practical evaluation of popular volume rendering algorithms (2000)
Michael Meißner, Jian Huang, Dirk Bartz, Klaus Mueller, Roger Crawfis
This paper evaluates and compares four volume rendering algorithms that have become rather popular for rendering datasets described on uniform rectilinear grids: raycasting, splatting, shear-warp,...
Efficient estimation of the partly linear additive Cox model (1999)
The partly linear additive Cox model is an extension of the (linear) Cox model and allows flexible modeling of covariate effects semiparametrically. We study asymptotic properties of the maximum...
Application of nanosphere and microsphere delivery in genetic immunization against HIV-1 / (1999)
Vita.
High-Quality Splatting on Rectilinear Grids with Efficient Culling of Occluded Voxels (1999)
Klaus Mueller, Naeem Shareef, Jian Huang, Roger Crawils
Abstract--Splatting is a popular volume rendering algorithm that pairs good image quality with an efficient volume projection scheme. The current axis-aligned sheet-buffer approach, however, bears...
Improving Value Prediction by Exploiting Both Operand and Output Value Locality (1999)
Youngsoo Choi, Joshua J. Yi, Jian Huang, David J. Lilja
Existing value reuse and prediction schemes use a hardware prediction table or reuse buffer to store an instruction’s value history based on its program. The result cache [17], on the other hand,...
Exploiting Basic Block Value Locality with Block Reuse (1999)
Jian Huang, Jian Huang, David J. Lilja, David J. Lilja
Speculative execution and instruction reuse are two important strategies that have been investigated for improving processor performance. Value prediction at the instruction level has been introduced...
Improving Value Prediction by Exploiting Both Operand and Output Value Locality (1999)
Jian Huang And, Jian Huang, Youngsoo Choi, David J. Lilja
Several studies have determined that the values produced by the execution of a program's instructions are often quite repetitive. There are basically two approaches that have been proposed for...
Design of Multichannel QMF Banks via Frequency Domain Optimizations (1999)
Jian Huang, Guoxiang Gu, Belle A. Shenoi
Design of uniform multirate filter banks is studied via frequency domain optimizations. Efficient and reliable design algorithms are developed using state-space computations. In our approach analysis...
The Superthreaded Processor Architecture (1999)
Jenn-yuan Tsai, Jian Huang, Christoffer Amlo, David J. Lilja, Pen-chung Yew
The common single-threaded execution model limits processors to exploiting only the relatively small amount of instruction-level parallelism available in application programs. The superthreaded...
High-Quality Splatting on Rectilinear Grids with Efficient Culling of Occluded Voxels (1999)
Klaus Mueller, Naeem Shareef, Jian Huang, Roger Crawfis
AbstractÐSplatting is a popular volume rendering algorithm that pairs good image quality with an efficient volume projection scheme. The current axis-aligned sheet-buffer approach, however, bears...
Efficient estimation of the partly linear additive Cox (1999)
Abstract: The partly linear additive Cox model is an extention of the (linear) Cox model and allows flexible modeling of covariate effects semiparametrically. We study asymptotic properties of the...
Thesis (M.S.)--University of Nebraska--Lincoln, 1998.
Thermal lattice BGK models for fluid dynamics / (1998)
Thesis (Ph. D.)--Drexel University, 1998.
Thesis (M.S.)--UCLA, 1998.
Improving Instruction-Level Parallelism by Exploiting Global Value Locality (1998)
Jian Huang, Jian Huang, David J. Lilja, David J. Lilja
Several studies have pointed out that the values produced by the execution of a program’s instructions are often quite repetitive. There are basically two approaches that have been proposed for...
David J. Lilja, Jian Huang, Jian Huang
In developing a simulator for a new processor architecture, it often is not clear whether it is more efficient to write a new simulator or to modify an existing simulator. Writing a new simulator...
Improving Instruction-Level Parallelism by Exploiting Global Value Locality (1998)
Several studies have pointed out that the values produced by the execution of a program's instructions are often quite repetitive. There are basically two approaches that have been proposed for...
An Accurate Method To Voxelize Polygonal Meshes (1998)
Jian Huang, Roni Yagel, Vassily Filippov, Yair Kurzion
The process of generating discrete surfaces in a volumetric representation, termed voxelization, is confronted with topological considerations as well as accuracy and efficiency requirements. We...
A Direct Approach to the Design of QMF Banks via Frequency Domain Optimizations (1998)
Jian Huang And, Jian Huang, Guoxiang Gu
This paper studies the design of quadrature mirror filter (QMF) banks via frequency domain optimizations. A direct approach is adopted that gives the necessary and sufficient condition for perfect...
Exploiting Basic Block Value Locality with Block Reuse (1998)
Speculative execution and instruction reuse are two important strategies that have been investigated for improving processor performance. Value prediction at the instruction level has been introduced...
In developing a simulator for a new processor architecture, it often is not clear whether it is more efficient to write a new simulator from scratch or whether it is better to try and modify an...
Improving Instruction-Level Parallelism by Exploiting Global Value Locality (1998)
Several studies have pointed out that the values produced by the execution of a program's instructions are often quite repetitive. There are basically two approaches that have been proposed for...
In developing a simulator for a new processor architecture, it often is not clear whether it is more efficient to write a new simulator or to modify an existing simulator. Writing a new simulator...
Exploiting Basic Block Value Locality with Block Reuse (1998)
Value prediction at the instruction level has been introduced to allow more aggressive speculation and reuse than previous techniques. We investigate the input and output values of basic blocks and...
Improving Instruction-Level Parallelism by Exploiting Global Value Locality (1998)
Several studies have pointed out that the values produced by the execution of a program’s instructions are often quite repetitive. There are basically two approaches that have been proposed for...
Asymptotic properties of the NPMLE of a distribution function based on ranked set samples (1997)
We show that the nonparametric maximum likelihood estimator (NPMLE) of a distribution function based on balanced ranked set samples is consistent, converges weakly to a Gaussian process and is...
Convergence Results on the Design of QMF Banks (1997)
This paper considers the design of quadrature mirror filter (QMF) banks whose analysis and synthesis filters are FIR and have linear phase. The design criterion is of least-squares type. An iterative...
Interval Censored Survival Data: A Review of Recent Progress (1997)
We review estimation in interval censoring models, including nonparametric estimation of a distribution function and estimation of regression models. In the nonparametric setting, we describe...
Asymptotic theory for nonparametric estimation of survival curves under order restrictions (1996)
Præstgaard, Jens Thomas, Huang, Jian
We consider two problems in nonparametric survival analysis under the restriction of stochastic ordering. The first problem is that of estimating a survival function $\overline{F}(t)$ under the...
Efficient estimation for the proportional hazards model with interval censoring (1996)
The maximum likelihood estimator (MLE) for the proportional hazards model with "case 1" interval censored data is studied. It is shown that the MLE for the regression parameter is asymptotically...
Efficient Estimation for the Cox Model with Interval Censoring (1996)
The maximum likelihood estimator (MLE) for the proportional hazards model with current status data is studied. It is shown that the MLE for the regression parameter is asymptotically normal with p...
Hydraulic exercise machine / (1996)
Thesis (M. Sc. Physics)--University of Waikato, 1996.
Interval censored survival data: a review of recent progress (1996)
We review estimation in interval censoring models, including nonparametric estimation of a distribution function and estimation of regression models. In the nonparametric setting, we describe...
Typescript (photocopy)
Abstract The maximum likelihood estimator (MLE) for the proportional hazards model with current status data is studied. It is shown that the MLE for the regression parameter is asymptotically normal...
CENTRAL LIMIT THEOREMS FOR M-ESTIMATES by (1993)
New simple sufficient conditions are given for M-estimators to satisfy a central limit theorem. The conditions mainly concern the combinatorial properties of the class of criterion functions. The...
Hazard under Random Censoring (1993)
Jian Huang, Jon A. Wellner, Jian Huang, Jon A. 'vellner
Consider nonparametric estimation of a decreasing density function f under the random (right) censorship model. Alternatively, consider estimation of a monotone increasing (or decreasing) hazard rate...
Maximum scored likelihood estimation of a linear regression with interval censored data (1993)
linear regression model with interval censored data
Surface modification of semiconductor electrodes and microelectrochemistry /--by Jian Huang. (1991)
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1991.
Xu, Xiang-Ru, Huang, Jian, Xu, Zhi-Gang, Qian, Bin-Zhi, Zhu, Zhi-Dong, Yan, Qing, ...
Human hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. In this work, we report on a comprehensive characterization of gene expression profiles of hepatitis B virus-positive...
CD8+-T-Cell Depletion Ameliorates Circulatory Shock in Plasmodium berghei-Infected Mice
Chang, Wun-Ling, Jones, Steven P., Lefer, David J., Welbourne, Tomas, Sun, Guang, Yin, Lijia, ...
The Plasmodium berghei-infected mouse model is a well-recognized model for human cerebral malaria. Mice infected with P. berghei exhibit (i) metabolic acidosis (pH < 7.3) associated with elevated...
Wu, Frederick Y., Chen, Honglin, Wang, Shizhen Emily, ApRhys, Collette M. J., Liao, Gangling, Fujimuro, Masahiro, ...
Cellular CCAAT/enhancer binding protein α (C/EBPα) promotes cellular differentiation and has antimitotic activities involving cell cycle arrest at G1/S through stabilization of p21CIP-1/WAF1 and...
Hsu, Jing-mei, Huang, Jian, Meluh, Pamela B., Laurent, Brehon C.
The accurate segregation of chromosomes requires the kinetochore, a complex protein machine that assembles onto centromeric DNA to mediate attachment of replicated sister chromatids to the mitotic...
The exon context and distribution of Euascomycetes rRNA spliceosomal introns
Bhattacharya, Debashish, Simon, Dawn, Huang, Jian, Cannone, Jamie J, Gutell, Robin R
Qiao, Hong, Wang, Hongyun, Zhao, Lan, Zhou, Junli, Huang, Jian, Zhang, Yansheng, ...
Self-incompatibility S-locus–encoded F-box (SLF) proteins have been identified in Antirrhinum and several Prunus species. Although they appear to play an important role in self-incompatible...
Isotani, Eiji, Zhi, Gang, Lau, Kim S., Huang, Jian, Mizuno, Yusuke, Persechini, Anthony, ...
Ca2+/calmodulin (CaM)-dependent phosphorylation of myosin regulatory light chain (RLC) by myosin light chain kinase (MLCK) initiates smooth muscle contraction and regulates actomyosin-based...
Liao, Gangling, Huang, Jian, Fixman, Elizabeth D., Hayward, S. Diane
Herpesviruses encode a set of core proteins essential for lytic replication of their genomes. Three of these proteins form a tripartite helix-primase complex that, in the case of Epstein-Barr virus...
Regulation of Expression of the Epstein-Barr Virus BamHI-A Rightward Transcripts
Chen, Honglin, Huang, Jian, Wu, Frederick Y., Liao, Gangling, Hutt-Fletcher, Lindsey, Hayward, S. Diane
The Epstein-Barr virus (EBV) BamHI-A rightward transcripts, or BARTs, are a family of mRNAs expressed in all EBV latency programs, including EBV-infected B cells in healthy carriers. Despite their...
A robust two-way semi-linear model for normalization of cDNA microarray data
Wang, Deli, Huang, Jian, Xie, Hehuang, Manzella, Liliana, Soares, Marcelo Bento
Chai, Bob, Huang, Jian, Cairns, Bradley R., Laurent, Brehon C.
The failure of cells to repair damaged DNA can result in genomic instability and cancer. To efficiently repair chromosomal DNA lesions, the repair machinery must gain access to the damaged DNA in the...
It has been demonstrated in the literature that the transmission/disequilibrium test (TDT) has higher power than the affected-sib-pair (ASP) mean test when linkage disequilibrium (LD) is strong but...
Huang, Jian, Liao, Gangling, Chen, Honglin, Wu, Frederick Y., Hutt-Fletcher, Lindsey, Hayward, Gary S., ...
The contribution of C/EBP proteins to Epstein-Barr virus (EBV) lytic gene expression and replication in epithelial cells was examined. Nasopharyngeal carcinoma cell lines constitutively expressed...
Zhi, Gang, Ryder, Jeffrey W., Huang, Jian, Ding, Peiguo, Chen, Yue, Zhao, Yingming, ...
Repetitive stimulation potentiates contractile tension of fast-twitch skeletal muscle. We examined the role of myosin regulatory light chain (RLC) phosphorylation in this physiological response by...
Chiang, Annie P., Beck, John S., Yen, Hsan-Jan, Tayeh, Marwan K., Scheetz, Todd E., Swiderski, Ruth E., ...
The identification of mutations in genes that cause human diseases has largely been accomplished through the use of positional cloning, which relies on linkage mapping. In studies of rare diseases,...
MIMOX: a web tool for phage display based epitope mapping
Huang, Jian, Gutteridge, Alex, Honda, Wataru, Kanehisa, Minoru
Xu, Xiang-Ru, Huang, Jian, Xu, Zhi-Gang, Qian, Bin-Zhi, Zhu, Zhi-Dong, Yan, Qing, ...
Human hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. In this work, we report on a comprehensive characterization of gene expression profiles of hepatitis B virus-positive...
CD8+-T-Cell Depletion Ameliorates Circulatory Shock in Plasmodium berghei-Infected Mice
Chang, Wun-Ling, Jones, Steven P., Lefer, David J., Welbourne, Tomas, Sun, Guang, Yin, Lijia, ...
The Plasmodium berghei-infected mouse model is a well-recognized model for human cerebral malaria. Mice infected with P. berghei exhibit (i) metabolic acidosis (pH < 7.3) associated with elevated...
Wu, Frederick Y., Chen, Honglin, Wang, Shizhen Emily, ApRhys, Collette M. J., Liao, Gangling, Fujimuro, Masahiro, ...
Cellular CCAAT/enhancer binding protein α (C/EBPα) promotes cellular differentiation and has antimitotic activities involving cell cycle arrest at G1/S through stabilization of p21CIP-1/WAF1 and...
Hsu, Jing-mei, Huang, Jian, Meluh, Pamela B., Laurent, Brehon C.
The accurate segregation of chromosomes requires the kinetochore, a complex protein machine that assembles onto centromeric DNA to mediate attachment of replicated sister chromatids to the mitotic...
The exon context and distribution of Euascomycetes rRNA spliceosomal introns
Bhattacharya, Debashish, Simon, Dawn, Huang, Jian, Cannone, Jamie J, Gutell, Robin R
Qiao, Hong, Wang, Hongyun, Zhao, Lan, Zhou, Junli, Huang, Jian, Zhang, Yansheng, ...
Self-incompatibility S-locus–encoded F-box (SLF) proteins have been identified in Antirrhinum and several Prunus species. Although they appear to play an important role in self-incompatible...
Isotani, Eiji, Zhi, Gang, Lau, Kim S., Huang, Jian, Mizuno, Yusuke, Persechini, Anthony, ...
Ca2+/calmodulin (CaM)-dependent phosphorylation of myosin regulatory light chain (RLC) by myosin light chain kinase (MLCK) initiates smooth muscle contraction and regulates actomyosin-based...
Liao, Gangling, Huang, Jian, Fixman, Elizabeth D., Hayward, S. Diane
Herpesviruses encode a set of core proteins essential for lytic replication of their genomes. Three of these proteins form a tripartite helix-primase complex that, in the case of Epstein-Barr virus...
Regulation of Expression of the Epstein-Barr Virus BamHI-A Rightward Transcripts
Chen, Honglin, Huang, Jian, Wu, Frederick Y., Liao, Gangling, Hutt-Fletcher, Lindsey, Hayward, S. Diane
The Epstein-Barr virus (EBV) BamHI-A rightward transcripts, or BARTs, are a family of mRNAs expressed in all EBV latency programs, including EBV-infected B cells in healthy carriers. Despite their...
A robust two-way semi-linear model for normalization of cDNA microarray data
Wang, Deli, Huang, Jian, Xie, Hehuang, Manzella, Liliana, Soares, Marcelo Bento
Chai, Bob, Huang, Jian, Cairns, Bradley R., Laurent, Brehon C.
The failure of cells to repair damaged DNA can result in genomic instability and cancer. To efficiently repair chromosomal DNA lesions, the repair machinery must gain access to the damaged DNA in the...
Many complex diseases are usually considered as dichotomous traits but are also associated with quantitative biological markers or quantitative risk factors. For such dichotomous traits, although...
Vieland, Veronica J., Huang, Jian
The observation of multiple linkage signals in the course of conducting genome screens for complex disorders raises the question of whether distinct genes represent independent causes of disease...
It has been demonstrated in the literature that the transmission/disequilibrium test (TDT) has higher power than the affected-sib-pair (ASP) mean test when linkage disequilibrium (LD) is strong but...
Zhi, Gang, Ryder, Jeffrey W., Huang, Jian, Ding, Peiguo, Chen, Yue, Zhao, Yingming, ...
Repetitive stimulation potentiates contractile tension of fast-twitch skeletal muscle. We examined the role of myosin regulatory light chain (RLC) phosphorylation in this physiological response by...
Huang, Jian, Liao, Gangling, Chen, Honglin, Wu, Frederick Y., Hutt-Fletcher, Lindsey, Hayward, Gary S., ...
The contribution of C/EBP proteins to Epstein-Barr virus (EBV) lytic gene expression and replication in epithelial cells was examined. Nasopharyngeal carcinoma cell lines constitutively expressed...
Chiang, Annie P., Beck, John S., Yen, Hsan-Jan, Tayeh, Marwan K., Scheetz, Todd E., Swiderski, Ruth E., ...
The identification of mutations in genes that cause human diseases has largely been accomplished through the use of positional cloning, which relies on linkage mapping. In studies of rare diseases,...
MIMOX: a web tool for phage display based epitope mapping
Huang, Jian, Gutteridge, Alex, Honda, Wataru, Kanehisa, Minoru
Regulation of gene expression in the mammalian eye and its relevance to eye disease
Scheetz, Todd E., Kim, Kwang-Youn A., Swiderski, Ruth E., Philp, Alisdair R., Braun, Terry A., Knudtson, Kevin L., ...
We used expression quantitative trait locus mapping in the laboratory rat (Rattus norvegicus) to gain a broad perspective of gene regulation in the mammalian eye and to identify genetic variation...
Huang, Jian, Chen, Feng, Del Casino, Cecilia, Autino, Antonella, Shen, Mouhua, Yuan, Shuai, ...
Exhibiting rapid polarized growth, the pollen tube delivers the male gametes into the ovule for fertilization in higher plants. To get an overall picture of gene expression during pollen germination...
Genome-wide linkage analysis of blood pressure under locus heterogeneity
Yang, Xinqun, Wang, Kai, Huang, Jian, Vieland, Veronica J
We describe a method for mapping quantitative trait loci that allows for locus heterogeneity. A genome-wide linkage analysis of blood pressure was performed using sib-pair data from the Framingham...
Identification and characterization of OGG1 mutations in patients with Alzheimer's disease
Mao, Guogen, Pan, Xiaoyu, Zhu, Bei-Bei, Zhang, Yanbin, Yuan, Fenghua, Huang, Jian, ...
Patients with Alzheimer's disease (AD) exhibit higher levels of 8-oxo-guanine (8-oxoG) DNA lesions in their brain, suggesting a reduced or defective 8-oxoG repair. To test this hypothesis, this study...
Jahrsdörfer, Bernd, Blackwell, Sue E., Wooldridge, James E., Huang, Jian, Andreski, Melinda W., Jacobus, Laura S., ...
B cells currently are not viewed as being capable of producing granzyme B or being cytotoxic. We found that B-chronic lymphocytic leukemia (B-CLL) cells treated with interleukin-21 (IL-21) produce...
On the Bootstrap of the Maximum Score Estimator
This paper shows that the bootstrap does not consistently estimate the asymptotic distribution of the maximum score estimator. The theory developed also applies to other estimators within a cube-root...
Feng, Weiguo, Huang, Jian, Zhang, Jian, Williams, Trevor
Tcfap2a, the gene encoding the mouse AP-2α transcription factor, is required for normal development of multiple structures during embryogenesis, including the face and limbs. Using comparative...
Estimation of the mean function with panel count data using monotone polynomial splines
We study nonparametric likelihood-based estimators of the mean function of counting processes with panel count data using monotone polynomial splines. The generalized Rosen algorithm, proposed by...
Performance Evaluation of Memory Allocation Schemes on CC-NUMA Multiprocessors
Trung N. Nguyen, Zhiyuan Li, Jian Huang, Guohua Jin, Dongsoo Kim
Cache Coherent Non-Uniform Memory Access (CC-NUMA) architectures have received strong interests from both academia and industries. This paper studies the performance impact of design choices at...
Reducing Cache Misses for CC-NUMA by Careful Page-Mapping
Careful page mapping has been shown in the past to be effective for reducing cache conflicts on both uniprocessor and Uniform Memory Access (UMA) multiprocessors. This paper extends previous...
Reducing Cache Misses for CC-NUMA by Careful Page-Mapping
Careful page mapping has been shown in the past to be effective for reducing cache conflicts on both uniprocessor and Uniform Memory Access (UMA) multiprocessors. This paper extends previous...
Reducing Cache Misses for CC-NUMA by Careful Page-mapping
Careful page mapping has been shown in the past to be effective for reducing cache conflicts on both uniprocessor and Uniform Memory Access (UMA) multiprocessors. We extend previous page-mapping...
Which preventive measures might protect health care workers from SARS?
Chen, Wei-Qing, Ling, Wen-Hua, Lu, Ci-Yong, Hao, Yuan-Tao, Lin, Zhong-Ning, Ling, Li, ...
Combining Clinical and Genomic Covariates via Cov-TGDR
Clinical covariates such as age, gender, tumor grade, and smoking history have been extensively used in prediction of disease occurrence and progression. On the other hand, genomic biomarkers...
A group bridge approach for variable selection
Jian Huang, Shuange Ma, Huiliang Xie, Cun-Hui Zhang
In multiple regression problems when covariates can be naturally grouped, it is important to carry out feature selection at the group and within-group individual variable levels simultaneously. The...
Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo
Mizuno, Yusuke, Isotani, Eiji, Huang, Jian, Ding, Hailei, Stull, James T., Kamm, Kristine E.
Ca2+/calmodulin (CaM)-dependent phosphorylation of myosin regulatory light chain (RLC) in smooth muscle by myosin light chain kinase (MLCK) and dephosphorylation by myosin light chain phosphatase...
Dosdall, Derek J., Tabereaux, Paul B., Kim, Jong J., Walcott, Gregory P., Rogers, Jack M., Killingsworth, Cheryl R., ...
Endocardial mapping has suggested that Purkinje fibers may play a role in the maintenance of long-duration ventricular fibrillation (LDVF). To determine the influence of Purkinje fibers on LDVF, we...
Penalized feature selection and classification in bioinformatics
In bioinformatics studies, supervised classification with high-dimensional input variables is frequently encountered. Examples routinely arise in genomic, epigenetic and proteomic studies. Feature...
Mining novel biomarkers for prognosis of gastric cancer with serum proteomics
Qiu, Fu-Ming, Yu, Jie-Kai, Chen, Yi-Ding, Jin, Qi-Feng, Sui, Mei-Hua, Huang, Jian
Guo, Yuanbiao, Zhang, Xuequn, Huang, Jian, Zeng, Yan, Liu, Wei, Geng, Chao, ...
In fetal hematopoietic organs, the switch from hematopoiesis is hypothesized to be a critical time point for organogenesis, but it is not yet evidenced. The transient coexistence of hematopoiesis...