Jian Shen

On the Spectrum of Middle-Cubes (2009)

Qiu, Ke, Qiu, Rong, Jiang, Yong, Shen, Jian

A middle-cube is an induced subgraph consisting of nodes at the middle two layers of a hypercube. The middle-cubes are related to the well-known Revolving Door (Middle Levels) conjecture. We study...

A bound on the scrambling index of a primitive matrix using Boolean rank (2009)

Akelbek, Mahmud, Fital, Sandra, Shen, Jian

The scrambling index of an $n\times n$ primitive matrix $A$ is the smallest positive integer $k$ such that $A^k(A^{t})^k=J$, where $A^t$ denotes the transpose of $A$ and $J$ denotes the $n\times n$...

On the Borel-Cantelli Lemma and its Generalization (2009)

Feng, Chunrong, Li, Liangpan, Shen, Jian

Let $\{A_n\}_{n=1}^{\infty}$ be a sequence of events on a probability space $(\Omega,\mathcal{F},\mathbf{P})$. We show that if $\lim_{m\to\infty}\sum_{n=1}^{m}w_n\mathbf{P}(A_n)=\infty$ where each...

On the Chudnovsky-Seymour-Sullivan Conjecture on Cycles in Triangle-free Digraphs (2009)

Chen, Kevin, Karson, Sean, Liu, Dan, Shen, Jian

For a simple digraph $G$ without directed triangles or digons, let $\beta(G)$ be the size of the smallest subset $X \subseteq E(G)$ such that $G\setminus X$ has no directed cycles, and let...

Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites (2009)

Mattei, Josiemer, Parnell, Laurence D, Lai, Chao-Qiang, Garcia-Bailo, Bibiana, Adiconis, Xian, Shen, Jian, ...

Abstract Background Variations in gene allele frequencies can contribute to differences in the prevalence of some common complex diseases among populations. Natural selection modulates the balance in...

The kth Upper Bases of Primitive Non-powerful Signed Digraphs (2009)

Shao, Yanling, Shen, Jian, Gao, Yubin

In this paper, we study the kth upper bases of primitive non-powerful signed digraphs. A bound on the kth upper bases of all primitive non-powerful signed digraphs is obtained, and the equality case...

Analyzing the Accuracy of the Fitch Method for Reconstructing Ancestral States on Ultrametric Phylogenies (2009)

Zhang, Louxin, Shen, Jian, Yang, Jialiang, Li, Guoliang

Recurrence formulas are presented for studying the accuracy of the Fitch method for reconstructing the ancestral states in a given phylogenetic tree. As their applications, we analyze the convergence...

A sum-division estimate of reals (2009)

Li, Liangpan, Shen, Jian

Let $A$ be a finite set of positive real numbers. We present a sum-division estimate: |A+A|^2|A/A|\geq\frac{|A|^4}{4}.

Geometric bionics: Lotus effect helps polystyrene nanotube films get good blood compatibility (2009)

Chun Mao, Wen-Bo Zhao, Wen-Ping Luo, Cun-Xia Liang, Xiao-Mei Hou, Xiao-Hua Huang, ...

Various biomaterials have been widely used for manufacturing biomedical applications including artificial organs, medical devices and disposable clinical apparatus, such as vascular prostheses, blood...

Keyword Detection in Natural Language Based on Statistical Mechanics of Words in Written Texts (2009)

Koroutchev, Kostadin, Shen, Jian, Koroutcheva, Elka, Cebrian, Manuel

In this work, we suggest a parameterized statistical model (the gamma distribution) for the frequency of word occurrences in long strings of English text and use this model to build a corresponding...

ON GENERALIZED EXPONENTS OF TOURNAMENTS (2008)

Bo Zhou, Jian Shen

Abstract. We determine two types of generalized exponent sets for tournaments with given order. In the course of proving the main results we find the following result, which may be interesting in its...

Extension of Strongly Regular Graphs (2008)

Ralucca Gera, Jian Shen

The Friendship theorem states that if any two people in a party have exactly one common friend, then there exists a politician who is a friend of everybody. In this paper, we generalize the...

r-Indecomposable and r-Nearly Decomposable Matrices ∗ Abstract (2008)

Lihua You, Bolian Liu, Jian Shen

Let n, r be integers with 0 ≤ r ≤ n − 1. An n × n matrix A is called r-partly decomposable if it contains a k×l zero submatrix with k+l = n−r+1. A matrix which is not r-partly decomposable...

Comparison of the CEST and SLOSH Models for Storm Surge Flooding (2008)

Keqi Zhang, Chengyou Xiao, Jian Shen

The Coastal and Estuarine Storm Tide (CEST) model for the boundary-fitted curvilinear grid has been developed recently to simulate a hurricane-induced storm surge. A new wetting-drying algorithm was...

Discretization Schemes on Triangular Grids 1 (2007)

Richard E. Ewing, Ove Saevareid, Jian Shen

Physical applications posed on irregular domains have caused difficulties in the use of many otherwise effective discretization schemes. In two dimensional examples, we consider discretization...

A DISCRETIZATION SCHEME AND ERROR ESTIMATE FOR FIRST-ORDER SYSTEMS AND ELLIPTIC PROBLEMS (2007)

Richard E. Ewing, Jian Shen, Discrete L

A discretization scheme applicable to the direct approximation of the velocity variable for either a first-order system or second-order elliptic equation is proposed in this paper. The scheme is...

Superconvergent Error Estimates for a Class of Discretization Methods for a Coupled First-Order (2007)

System Discontinuous Coecients, Richard E. Ewing, Jian Shen

Lithological discontinuities in a reservoir generate discontinuous coecients for the rst-order system of equations used in the simulation of uid ow in porous media. Systems of conservation laws with...

On a Problem of Lewin (2007)

Jian Shen, Stewart Neufeld

A digraph G is called primitive if for some positive integer k, there is a walk of length exactly k from each vertex u to each vertex v (possibly u again). If G is primitive, the smallest such k is...

On The Design Of A Transversal Filter Bank For Parallel Processing Multiple Image Lines In Real-Time Acoustic Imaging (2007)

Jian Shen, Emad S. Ebbini

We present a new method for designing a transversal filter bank for parallel processing echo data in real-time active acoustic imaging. The method is based on a discretized linear spatio-temporal...

Received??; Revised?? Editors:?? (2007)

Jian Shen, Jacob A. Abraham

Abstract. Recent studies show that at-speed functional tests are better for finding realistic defects than tests executed at lower speeds. This advantage has led to growing interest in design for...

Functional Self-Test Generation for Superscalar Microprocessors (2007)

Jian Shen, Jacob A. Abraham, Navin Chander

Functional testing of microprocessors has been studied for over two decades. Techniques for generating functional tests for modern microprocessors with cache/MMU and pipelining have been previously...

A note on the number of edges guaranteeing a C 4 in Eulerian bipartite digraphs (2007)

Jian Shen, Raphael Yuster

Let G be an Eulerian bipartite digraph with vertex partition sizes m,n.We prove the following Turan-type result: If e(G) > 2mn/3thenG contains a directed cycle of length at most 4. The result is...

Eulerian bipartite digraphs (2007)

Jian Shen, Raphael Yuster

Let G be an Eulerian bipartite digraph with vertex partition sizes m;n. We prove the following Turan-type result: If e(G)> 2mn=3 then G contains a directed cycle of length at most 4. The result is...

Density Conditions for Triangles in Multipartite (2007)

Graphs Adrian Bondy, Adrian Bondy, Jian Shen, Carsten Thomassen

We consider the problem of nding a large or dense triangle-free subgraph in a given graph G. In response to a question of P. Erd}os, we prove that, if the minimum degree of G is at least 9jV (G)j=10,...

Approximating the spanning star forest problem and its applications to genomic sequence alignment (2007)

C. Thach Nguyen, Jian Shen, Minmei Hou, Li Sheng, Webb Miller, Louxin Zhang

Abstract. This paper studies the algorithmic issues of the spanning star forest problem. We prove the following results: (1) There is a polynomial-time approximation scheme for planar graphs; (2)...

Numerical simulation of an estuarine front using an unstructured grid model (2006)

Shen, Jian, Sisson, Mac

Paper presented at The Seventh International Conference on HydroScience and Engineering (ICHE) hosted by the College of Engineering at Drexel Univeristy on September 10-13, 2006 in Philadelphia,...

Examination of Chesapeake Bay Observing System for Local Environmental Data for Coast Guard Operations (2006)

Brubaker, John, Friedrichs, Carl, Harris, Courtney, Shen, Jian, Wang, Harry

The effective conduct of many of the U.S. Coast Guard's (USCG) missions is strongly influenced by the availability of accurate information on local environmental conditions. As an example, in search...

Density Conditions for Triangles in Multipartite Graphs (2006)

Bondy, Adrian, Shen, Jian, Thomasse, Stephan, Thomassen, Carsten

We consider the problem of finding a large or dense triangle-free subgraph in a given graph $G$. In response to a question of P. Erd\H{o}s, we prove that, if the minimum degree of $G$ is at least...

Density Conditions for Triangles in Multipartite Graphs (2006)

Bondy, Adrian, Shen, Jian, Thomasse, Stephan, Thomassen, Carsten

We consider the problem of finding a large or dense triangle-free subgraph in a given graph $G$. In response to a question of P. Erd\H{o}s, we prove that, if the minimum degree of $G$ is at least...

The Missense Genetic Polymorphisms of Human CYP2A13: Functional Significance in Carcinogen Activation and Identification of A Null Allelic Variant (2006)

Wang, Shou-Lin, He, Xiao-Yang, Shen, Jian, Wang, Jia-Sheng, Hong, Jun-Yan

Cytochrome P450 2A13 (CYP2A13), an enzyme predominantly expressed in human respiratory tissues, is highly efficient for the metabolic activation of two suspected human lung carcinogens...

The Missense Genetic Polymorphisms of Human CYP2A13: Functional Significance in Carcinogen Activation and Identification of A Null Allelic Variant (2006)

Wang, Shou-Lin, He, Xiao-Yang, Shen, Jian, Wang, Jia-Sheng, Hong, Jun-Yan

Cytochrome P450 2A13 (CYP2A13), an enzyme predominantly expressed in human respiratory tissues, is highly efficient for the metabolic activation of two suspected human lung carcinogens...

Double gate MOSFETs : process variations and design considerations / (2005)

Shen, Jian.

Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2005.

Double gate MOSFETs : process variations and design considerations / (2005)

Shen, Jian.

Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2005.

Characterizations of 1,k-bar visibility trees (2005)

Guantao Chen, Joan P. Hutchinson, Ken Keating, Jian Shen

A unit bar-visibility graph is a graph whose vertices can be represented in the plane by disjoint horizontal unit-length bars such that two vertices are adjacent if and only if there is a...

Double gate MOSFETs : process variations and design considerations (2005)

Shen, Jian

Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2005

Vehicle following with obstacle avoidance capabilities in natural environments (2004)

Teck Chew Ng, Javier Ibañez-guzmán, Jian Shen, Zhiming Gong

Abstract — A robust vehicle following system with obstacle avoidance capabilities for operation in natural environments is described in this paper. By combining a novel vehicle-tracking and...

Richard D.F. Harris* (2004)

Jian Shen

In this paper, we show that although minimum-variance hedging unambiguously reduces the standard deviation of portfolio returns, it tends to increase portfolio kurtosis and consequently the...

Second neighborhood via first neighborhood in digraphs (2003)

Guantao Chen, Jian Shen, Raphael Yuster

Let D be a simple digraph without loops or digons. For any v ∈ V (D), the first out-neighborhood N + (v) is the set of all vertices with out-distance 1 from v and the second neighborhood N ++ (v)...

Self-assembly of Nanometer-scale Magnetic Dots with Narrow Size Distributions on an Insulating Substrate (2002)

Gai, Zheng, Wu, Biao, Pierce, J. P., Farnan, G. A., Shu, Dajun, Wang, Mu, ...

The self-assembly of iron dots on the insulating surface of NaCl(001) is investigated experimentally and theoretically. Under proper growth conditions, nanometer-scale magnetic iron dots with...

Nonequivalent ArsA nucleotide binding site and preliminary studies of an ArsA homologue in yeast (2002)

Shen, Jian

The ars operon of plasmid R773 encodes an As(III)/Sb(III) extrusion pump. The catalytic subunit, ArsA ATPase, has two homologous halves, A1 and A2, each with a consensus nucleotide-binding site. ArsA...

Point-Distributed Algorithms on Locally Refined Grids for Second Order Elliptic Equations (2001)

Richard E. Ewing, Jian Shen, Junping Wang

A discretization scheme, which relates the mixed nite element method with cellcented nite dierence and nite volume element methods, is proposed for second-order elliptic equations on rectangular...

On the existence of a sorting sequence of kings in a tournament (2000)

Jian Shen, Li Sheng, Jie Wu

Abstract. A tournament Tn is an orientation of a complete graph on n vertices. A king in a tournament is a vertex from which every other vertex is reachable by a path of length at most 2. A sorted...

Effective techniques for processor validation and test / (1999)

Shen, Jian.

Thesis (Ph. D.)--University of Texas at Austin, 1999.

Effective techniques for processor validation and test / (1999)

Shen, Jian.

Thesis (Ph. D.)--University of Texas at Austin, 1999.

Effective techniques for processor validation and test / (1999)

Shen, Jian.

Thesis (Ph. D.)--University of Texas at Austin, 1999.

Functional verification of the equator MAP1000 microprocessor (1999)

Jian Shen, Jacob Abraham, Dave Baker, Tony Hurson, Martin Kinkade

The Advanced VLIW architecture of the Equator MAP1000 processor has many features that present significant verification challenges. We describe a functional verification methodology to address this...

Verification of Processor Microarchitectures (1999)

Jian Shen, Jacob A. Abraham

This paper develops a new abstraction technique for processor microarchitecture validation. An abstract finite-state machine model is derived directly from the processor HDL description. This model,...

Landau's Inequalities for Tournament Scores and a Short Proof of a Theorem on Transitive Sub-Tournaments (1999)

Richard A. Brualdi, Jian Shen

Ao and Hanson, and Guiduli, Gy'arf'as, Thomass'e and Weidl independently, proved the following result: For any tournament score sequence S = (s 1 ; s 2 ; : : : ; s n ) with s 1 s 2...

Discrepancy of Matrices of Zeros and Ones (1999)

Richard A. Brualdi, Jian Shen

Let m and n be positive integers, and let R =(r 1 ,...,r m)a ndS = (s 1 ,...,s n ) be non-negative integral vectors. Let A(R, S)bethesetofall m n (0, 1)-matrices with row sum vector R and column...

Discrepancy of Matrices of Zeros and Ones (1999)

Richard A. Brualdi, Jian Shen

Let m and n be positive integers, and let R = (r 1 ; : : : ; r m ) and S = (s 1 ; : : : ; s n ) be non-negative integral vectors. Let A(R;S) be the set of all m \Theta n (0; 1)-matrices with row sum...

Exponents of of 2-regular Digraphs (1999)

Jian Shen

A digraph G is called primitive if for some positive integer k, there is a walk of length exactly k from each vertex u to each vertex v (possibly u again). If G is primitive, the smallest such k is...

On the Girth of Digraphs (1998)

Jian Shen

It was conjectured by Caccetta and Haggkvist in 1978 that the girth of every digraph with n vertices and minimum outdegree r is at most dn=re. The conjecture was proved for r = 2 by Caccetta and...

Directed Triangles in Digraphs (1998)

Jian Shen

Let c be the smallest possible value such that every digraph on n vertices with minimum outdegree at least cn contains a directed triangle. It was conjectured by Caccetta and Haggkvist in 1978 that c...

Some Results on Generalized Exponents (1998)

Stewart Neufeld, Jian Shen

A digraph G = (V; E) is primitive if, for some positive integer k, there is a u ! v walk of length k for every pair u; v of vertices of V . The minimum such k is called the exponent of G, denoted...

Local Exponents of Primitive Digraphs (1998)

Jian Shen, Stewart Neufeld

A digraph G = (V; E) is primitive if, for some positive integer k, there is a u ! v walk of length k for every pair u; v of vertices of V . The minimum such k is called the exponent of G, denoted...

Native mode functional test generation for processors with applications to self test and design validation (1998)

Jian Shen, Jacob A. Abraham

New methodologies based on functional testing and built-in self-test can narrow the gap between necessary solutions and existing techniques for processor validation and testing. We presentaversatile...

Guest Editors (1997)

Jian Shen, Jacob A. Abraham

Abstract. Design validation is becoming more and more a bottleneck in the microprocessor design process. The difficulty of validation stems from the complexity of the design, which requires searching...

On combining formal and informal verification (1997)

Jian Shen, Jacob Abraham, Adnan Aziz

Abstract. We propose algorithms which combine simulation with symbolic methods for the verification of invariants. The motivation is twofold. First, there are designs which are too complex to be...

On the Caccetta-Häggkvist Conjecture (1997)

Jian Shen

It was conjectured by Caccetta and Haggkvist in 1978 that every digraph G with n vertices and minimum outdegree at least r contains a directed cycle of length at most dn=re. By refining an argument...

On Combining Formal and Informal Verification (1997)

Jun Yuan, Jian Shen, Jacob Abraham, Adnan Aziz

. We propose algorithms which combine simulation with symbolic methods for the verification of invariants. The motivation is two-fold. First, there are designs which are too complex to be formally...

Exponents of Vertex-transitive Digraphs (1996)

Jian Shen, D. A. Gregory

A digraph D is primitive if, for some positive integer r, there is a u ! v walk of length r for every pair u; v of vertices of D. The minimum such r is called the exponent of D, denoted exp(D). We...

Exponents of vertex-transitive digraphs (1996)

Jian Shen

A digraph D is primitive if, for some positive integer r, there is a u! v walk of length r for every pair u; v of vertices of D. The minimum such r is called the exponent ofD, denoted exp(D). We...

The analysis of multigrid algorithms for cell centered finite difference methods (1994)

James H. Bramble, Richard E. Ewing, Joseph E. Pasciak, Jian Shen

Abstract. In this paper, we examine multigrid algorithms for cell centered finite difference approximations of second order elliptic boundary value problems. The cell centered application gives rise...

The analysis of multigrid algorithms for cell centered finite difference methods (1994)

James H. Bramble, Richard E. Ewing, Joseph E. Pasciak, Jian Shen

Abstract. In this paper, we examine multigrid algorithms for cell centered finite difference approximations of second order elliptic boundary value problems. The cell centered application gives rise...

Mixed Finite Element Methods On Distorted Rectangular Grids (1994)

Jian Shen, R. D. Lazarov, J. M. Thomas

A new mixed finite element method on totally distorted rectangular meshes is introduced with optimal error estimates for both pressure and velocity. This new mixed discretization fits the geometric...

Point-distributed algorithms for second-order elliptic equations in mixed form (1993)

Richard E. Ewing, Jian Shen, Junping Wang

Abstract: A discretization scheme, which relates the mixed finite element method with cell-cented finite difference and finite volume element methods, is proposed for second-order elliptic equations...

A Multigrid Algorithm For The Cell-Centered Finite Difference Scheme (1993)

Richard E. Ewing, Jian Shen

this article, we discuss a non-variational V -cycle multigrid algorithm based on the cell-centered finite difference scheme for solving a second-order elliptic problem with discontinuous...

Short cycles in digraphs with local average outdegree at least two (1992)

Jian Shen

Suppose G is a strongly connected digraph with order n girth g and diameter d. We prove that d + g ≤ n if G contains no arcs (u, v) withdeg + (u) =1and deg + (v) ≤ 2. Caccetta and Häggkvist...

Short cycles in digraphs with local average outdegree at least two (1992)

Jian Shen

Suppose G is a strongly connected digraph with order n girth g and diameter d. We prove that d + g n if G contains no arcs (u; v) with deg

Pathways of As(III) detoxification in Saccharomyces cerevisiae

Ghosh, Mallika, Shen, Jian, Rosen, Barry P.

Saccharomyces cerevisiae has two independent transport systems for the removal of arsenite from the cytosol. Acr3p is a plasma membrane transporter that confers resistance to arsenite, presumably by...

Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9

Liu, Zijuan, Shen, Jian, Carbrey, Jennifer M., Mukhopadhyay, Rita, Agre, Peter, Rosen, Barry P.

Much is known about the transport of arsenite and antimonite into microbes, but the identities of mammalian transport proteins are unknown. The Saccharomyces cerevisiae FPS1 gene encodes a membrane...

Molecular Profiling of the Clostridium leptum Subgroup in Human Fecal Microflora by PCR-Denaturing Gradient Gel Electrophoresis and Clone Library Analysis

Shen, Jian, Zhang, Baorang, Wei, Guifang, Pang, Xiaoyan, Wei, Hua, Li, Min, ...

A group-specific PCR-based denaturing gradient gel electrophoresis (DGGE) method was developed and combined with group-specific clone library analysis to investigate the diversity of the Clostridium...

Pathways of As(III) detoxification in Saccharomyces cerevisiae

Ghosh, Mallika, Shen, Jian, Rosen, Barry P.

Saccharomyces cerevisiae has two independent transport systems for the removal of arsenite from the cytosol. Acr3p is a plasma membrane transporter that confers resistance to arsenite, presumably by...

Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9

Liu, Zijuan, Shen, Jian, Carbrey, Jennifer M., Mukhopadhyay, Rita, Agre, Peter, Rosen, Barry P.

Much is known about the transport of arsenite and antimonite into microbes, but the identities of mammalian transport proteins are unknown. The Saccharomyces cerevisiae FPS1 gene encodes a membrane...

Molecular Profiling of the Clostridium leptum Subgroup in Human Fecal Microflora by PCR-Denaturing Gradient Gel Electrophoresis and Clone Library Analysis

Shen, Jian, Zhang, Baorang, Wei, Guifang, Pang, Xiaoyan, Wei, Hua, Li, Min, ...

A group-specific PCR-based denaturing gradient gel electrophoresis (DGGE) method was developed and combined with group-specific clone library analysis to investigate the diversity of the Clostridium...

Roles of the Tumor Suppressor p53 and the Cyclin-dependent Kinase Inhibitor p21WAF1/CIP1 in Receptor-mediated Apoptosis of WEHI 231 B Lymphoma Cells

Wu, Min, Bellas, Robert E., Shen, Jian, Sonenshein, Gail E.

Treatment of WEHI 231 immature B lymphoma cells with an antibody against their surface immunoglobulin M (anti-IgM) induces apoptosis and has been studied extensively as a model of self-induced B cell...

Symbiotic gut microbes modulate human metabolic phenotypes

Li, Min, Wang, Baohong, Zhang, Menghui, Rantalainen, Mattias, Wang, Shengyue, Zhou, Haokui, ...

Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome) and individual variations in the microbiome influence host health, may be implicated in disease...

Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study

Tanaka, Toshiko, Shen, Jian, Abecasis, Gonçalo R., Kisialiou, Aliaksei, Ordovas, Jose M., Guralnik, Jack M., ...

Polyunsaturated fatty acids (PUFA) have a role in many physiological processes, including energy production, modulation of inflammation, and maintenance of cell membrane integrity. High plasma PUFA...

The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN study*

Shen, Jian, Arnett, Donna K., Pérez-Martínez, Pablo, Parnell, Laurence D., Lai, Chao-Qiang, Peacock, James M., ...

Chronically elevated interleukin-6 (IL-6) affects lipid and lipoprotein metabolism. Individuals genetically predisposed to higher IL-6 secretion may be at risk of dyslipidemia, especially during the...