Jian Zhang

Slicing: A New Approach to Privacy Preserving Data Publishing (2009)

Li, Tiancheng, Li, Ninghui, Zhang, Jian, Molloy, Ian

Several anonymization techniques, such as generalization and bucketization, have been designed for privacy preserving microdata publishing. Recent work has shown that generalization loses...

Highly Predictive Blacklisting (2009)

Jian Zhang, Phillip Porras, Johannes Ullrich

The notion of blacklisting communication sources has been a well-established defensive measure since the origins of the Internet community. In particular, the practice of compiling and sharing lists...

Spontaneous Vortex Lattices in Quasi 2D Dipolar Spinor Condensates (2009)

Zhang, Jian, HO, Tin-Lun

Motivated by recent experiments\cite{BA}\cite{BB}, we study quasi 2D ferromagnetic condensates with various aspect ratios. We find that in zero magnetic field, dipolar energy generates a local energy...

Modeling and Integrating Background Knowledge in Data Anonymization (2009)

Tiancheng Li, Ninghui Li, Jian Zhang

Abstract — Recent work has shown the importance of considering the adversary’s background knowledge when reasoning about privacy in data publishing. However, it is very difficult for the data...

Lack of association of TIM3polymorphisms and allergic phenotypes (2009)

Zhang, Jian, Daley, Denise, Akhabir, Loubna, Stefanowicz, Dorota, Chan-Yeung, Moira, Becker, Allan B, ...

Abstract Background T-cell immunoglobulin mucin-3 (TIM3) is a T H 1-specific type 1 membrane protein that regulates T H 1 proliferation and the development of immunological tolerance. TIM3 and its...

The Entire Quantile Path of a Risk-Agnostic SVM Classifier (2009)

Yu, Jin, S.V.N., Vishwanathan, Zhang, Jian

A quantile binary classifier uses the rule: Classify x as +1 if P(Y=1|X=x) >= tau, and as -1 otherwise, for a fixed quantile parameter tau in [0, 1]. It has been shown that Support Vector Machines...

Gaussian Process Learning for Cyber-Attack Early Warning ∗ (2009)

Jian Zhang, Phillip Porras, Johannes Ullrich

Network security has been a serious concern for many years. For example, firewalls often record thousands of exploit attempts on a daily basis. Network administrators could benefit from information...

Low-complexity estimation of CFO and frequency independent I/Q mismatch for OFDM systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

CFO and I/Q mismatch could cause significant performance degradation to OFDM systems. Their estimation and compensation are generally difficult as they are entangled in the received signal. In this...

Low-complexity estimation of CFO and frequency independent I/Q mismatch for OFDM systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

CFO and I/Q mismatch could cause significant performance degradation to OFDM systems. Their estimation and compensation are generally difficult as they are entangled in the received signal. In this...

Efficiently Learning a Detection Cascade with Sparse Eigenvectors (2009)

Shen, Chunhua, Paisitkriangkrai, Sakrapee, Zhang, Jian

In this work, we first show that feature selection methods other than boosting can also be used for training an efficient object detector. In particular, we introduce Greedy Sparse Linear...

Clipping Noise Compensation for OFDMA Systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

This paper presents an efficient low-complexity clipping noise compensation scheme for PAR reduced orthogonal frequency division multiple access (OFDMA) systems. Conventional clipping noise...

Basics (2009)

Jian Zhang

In the following we introduce the idea of Monte Carlo and show how to use it to solve integration problems.

Delineating the Citation Impact of Scientific Discoveries (2009)

Chaomei Chen, Jian Zhang

Identifying the significance of specific concepts in the diffusion of scientific knowledge is a challenging issue concerning many theoretical and practical areas. We introduce an innovative visual...

Parallel Execution of Stochastic Search Procedures on Reduced SAT Instances (2009)

Wenhui Zhang, Zhuo Huang, Jian Zhang

Abstract. We present a technique for checking instances of the satisfiability (SAT) problem based on a combination of the Davis-Putnam (DP) procedure and stochastic methods. We first use the DP...

Flexible Latent Variable Models for Multi-Task Learning (2009)

Jian Zhang, Zoubin Ghahramani, Yiming Yang

Summary. Given multiple prediction problems such as regression and classification, we are interested in a joint inference framework which can effectively borrow information among tasks to improve the...

NONPARAMETRIC DENSITY ESTIMATION (2009)

Jian Zhang

The probability density function (pdf) is a fundamental concept in statistics. Given the pdf f(x) of a random variable X, probabilities associated with X can be easily computed as � b P(a ≤ X...

ITERATIVE METHODS FOR OPTIMIZATION (2009)

Jian Zhang

With the aid of modern computers we are able to conduct an iterative search for optimum. As a general framework, assume that we want to minimize a function f and we are given an initial point x 1....

Clipping noise compensation for OFDMA systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

This paper presents an efficient low-complexity clipping noise compensation scheme for PAR reduced orthogonal frequency division multiple access (OFDMA) systems. Conventional clipping noise...

4,4-Diacetylheptanedinitrile (2009)

Guo-wei Wang, Jian Zhang, Ling-hua Zhuang, Wen-yuan Wu, Jin-tang Wang

The asymmetric unit of the title compound, C11H14N2O2, contains one half-molecule as the central C atom of the molecule lies on a twofold rotation axis. In the crystal structure, weak intermolecular...

Reduced-Rank Shift-Invariant Technique and Its Application for Synchronization and Channel Identification in UWB Systems (2009)

Jian (Andrew) Zhang, Rodney A. Kennedy, Thushara D. Abhayapala

We investigate reduced-rank shift-invariant technique and its application for synchronization and channel identification in UWB systems. Shift-invariant techniques, such as ESPRIT and the matrix...

Heteroatoms Increase the Selectivity in Oxidative Dehydrogenation Reactions on Nanocarbons (2009)

Frank, Benjamin, Zhang, Jian, Blume, Raoul, Schlögl, Robert, Su, Dang Sheng

Boron makes it selective: Carbon nanotubes (CNTs) modified by boron oxide catalyze the oxidative dehydrogenation of propane to propene with remarkable selectivity. Nanocarbon can be an attractive...

3-Methoxybenzaldehyde thiosemicarbazone (2009)

Jian Zhang, Lin-ping Wu, Ling-hua Zhuang, Guo-wei Wang

The title compound, C9H11N3OS, was prepared by the reaction of 3-methoxybenzaldehyde and thiosemicarbazide. The benzylidene ring and the thiosemicarbazone fragment are slightly twisted, making a...

Mechanical and unlubricated tribological properties of titanium-containing diamond-like carbon coatings (2009)

Ouyang, Jia-Hu, Sasaki, Shinya, Murakami, Takashi, Zhou, Yu, Zhang, Jian

Titanium-containing diamond-like carbon (Ti-DLC) coatings were deposited on steel with a close-field unbalanced magnetron sputtering in a mixed argon/acetylene atmosphere. The morphology and...

Advanced Receiver Design for Quadrature OFDMA Systems (2009)

Lin Luo, Jian (Andrew) Zhang, Zhenning Shi

Quadrature orthogonal frequency division multiple access (Q-OFDMA) systems have been recently proposed to reduce the peak-to-average power ratio (PAPR) and complexity, and improve carrier frequency...

Clipping Noise Compensation for OFDMA Systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

This paper presents an efficient low-complexity clipping noise compensation scheme for PAR reduced orthogonal frequency division multiple access (OFDMA) systems. Conventional clipping noise...

Low-complexity estimation of CFO and frequency independent I/Q mismatch for OFDM systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

CFO and I/Q mismatch could cause significant performance degradation to OFDM systems. Their estimation and compensation are generally difficult as they are entangled in the received signal. In this...

Clipping noise compensation for OFDMA systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

This paper presents an efficient low-complexity clipping noise compensation scheme for PAR reduced orthogonal frequency division multiple access (OFDMA) systems. Conventional clipping noise...

(E)-N′-(5-Chloro-2-hydroxybenzylidene)-4-(8-quinolyloxy)butanohydrazide monohydrate (2009)

Jian Zhang, Guo-Lun XiaHou, Sheng-Sen Zhang, Jing Zeng

The crystal of the title Schiff base compound, C20H18ClN3O3·H2O, was twinned by a twofold rotation about (100). The asymmetric unit contains two crystallographically independent molecules with...

Time Domain Equalizer Design Using Bit Error Rate Minimization for UWB Systems (2009)

Syed Imtiaz Husain, Jinhong Yuan, Jian Zhang, R. K. Martin

Ultra-wideband (UWB) communication systems occupy huge bandwidths with very low power spectral densities. This feature makes the UWB channels highly rich in resolvable multipaths. To exploit the...

Low-complexity estimation of CFO and frequency independent I/Q mismatch for OFDM systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

CFO and I/Q mismatch could cause significant performance degradation to OFDM systems. Their estimation and compensation are generally difficult as they are entangled in the received signal. In this...

Low-Complexity Estimation of CFO and Frequency Independent I/Q Mismatch for OFDM Systems (2009)

Ying Chen, Jian (Andrew) Zhang

CFO and I/Q mismatch could cause significant performance degradation to OFDM systems. Their estimation and compensation are generally difficult as they are entangled in the received signal. In this...

Clipping noise compensation for OFDMA systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

This paper presents an efficient low-complexity clipping noise compensation scheme for PAR reduced orthogonal frequency division multiple access (OFDMA) systems. Conventional clipping noise...

Clipping Noise Compensation for OFDMA Systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

This paper presents an efficient low-complexity clipping noise compensation scheme for PAR reduced orthogonal frequency division multiple access (OFDMA) systems. Conventional clipping noise...

Low-complexity estimation of CFO and frequency independent I/Q mismatch for OFDM systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

CFO and I/Q mismatch could cause significant performance degradation to OFDM systems. Their estimation and compensation are generally difficult as they are entangled in the received signal. In this...

PubChem: a public information system for analyzing bioactivities of small molecules (2009)

Wang, Yanli, Xiao, Jewen, Suzek, Tugba O., Zhang, Jian, Wang, Jiyao, Bryant, Stephen H.

PubChem (http://pubchem.ncbi.nlm.nih.gov) is a public repository for biological properties of small molecules hosted by the US National Institutes of Health (NIH). PubChem BioAssay database currently...

Human ZCCHC12 activates AP-1 and CREB signaling as a transcriptional co-activator (2009)

Li, Hong, Liu, Qian, Hu, Xiang, Feng, Du, Xiang, Shuanglin, He, Zhicheng, ...

Mouse zinc finger CCHC domain containing 12 gene (ZCCHC12) has been identified as a transcriptional co-activator of bone morphogenetic protein (BMP) signaling, and human ZCCHC12 was reported to be...

Advanced Receiver Design for Quadrature OFDMA Systems (2009)

Lin Luo, Jian (Andrew) Zhang, Zhenning Shi

Quadrature orthogonal frequency division multiple access (Q-OFDMA) systems have been recently proposed to reduce the peak-to-average power ratio (PAPR) and complexity, and improve carrier frequency...

Time Domain Equalizer Design Using Bit Error Rate Minimization for UWB Systems (2009)

Syed Imtiaz Husain, Jinhong Yuan, Jian Zhang, R. K. Martin

Ultra-wideband (UWB) communication systems occupy huge bandwidths with very low power spectral densities. This feature makes the UWB channels highly rich in resolvable multipaths. To exploit the...

Low-Complexity Estimation of CFO and Frequency Independent I/Q Mismatch for OFDM Systems (2009)

Ying Chen, Jian (Andrew) Zhang

CFO and I/Q mismatch could cause significant performance degradation to OFDM systems. Their estimation and compensation are generally difficult as they are entangled in the received signal. In this...

Protein-coding gene promoters in Methanocaldococcus (Methanococcus) jannaschii (2009)

Zhang, Jian, Li, Enhu, Olsen, Gary J.

Although Methanocaldococcus (Methanococcus) jannaschii was the first archaeon to have its genome sequenced, little is known about the promoters of its protein-coding genes. To expand our knowledge,...

Metal-Free Phenanthrenequinone Cyclotrimer as an Effective Heterogeneous Catalyst (2009)

Zhang, Jian, Wang, Xuan, Su, Qi, Zhi, Linjie, Thomas, Arne, Feng, Xinliang, ...

A phenanthrenequinone macrocyclic trimer was synthesized and used as a heterogeneous catalyst for oxidative dehydrogenation of ethylbenzene. This model molecule under comparable kinetic conditions is...

Heteroatome steigern die Selektivität der oxidativen Dehydrierung an Nanokohlenstoff (2009)

Frank, Benjamin, Zhang, Jian, Blume, Raoul, Schlögl, Robert, Su, Dang Sheng

Mit Bor kommt die Selektivität: Kohlenstoffnanoröhren (CNTs), die mit Boroxid modifiziert wurden, katalysieren die oxidative Dehydrierung von Propan zu Propen mit einer beachtlichen Selektivität....

Oxidative purification of carbon nanotubes and its impact on catalytic performance in ODH reactions (2009)

Rinaldi, Ali, Zhang, Jian, Frank, Benjamin, Su, Dang Sheng, Abd Hamid, Sharifah Bee, Schlögl, Robert

Oxidative purification with mild diluted HNO3 followed by NaOH washing lowers the amount of amorphous carbon deposited at multiwalled carbon nanotubes (CNTs). The graphitic structure can be...

Metal-free Heterogeneous Catalysis for a Sustainable Chemistry (2009)

Su, Dang Sheng, Zhang, Jian, Thomas, Arne, Wang, Xinchen, Paraknowitsch, Jens, Schlögl, Robert

The science and technology of catalysis are being challenged by the facts that fossil energy and other natural resources (among them water) are exhausting and the climate changes rapidly with global...

Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells (2009)

Ailan He, Xiangwen Xiao, Daolong Ren, Lu Gan, Xiaofeng Ding, Xi Qiao, ...

Abstract Background Activator protein 2 gamma (AP-2γ) is a member of the transcription factor activator protein-2 (AP-2) family, which is developmentally regulated and plays a role in human...

4-Methylbenzaldehyde thiosemicarbazone (2009)

Jian Zhang, Hao Geng, Ling-hua Zhuang, Guo-wei Wang

The title compound, C9H11N3S, was prepared by reacting 4-methylbenzaldehyde with thiosemicarbazide. An intramolecular N—H...N hydrogen bond helps to establish the observed molecular...

2-Bromo-1-(4-methoxyphenyl)ethanone (2009)

Jian Zhang, Ling-hua Zhuang, Guo-wei Wang

The title compound, C9H9BrO2, prepared by the reaction of 4-methoxyacetophenone and cupric bromide, , is approximately planar (r.m.s. deviation 0.0008 Å). In the crystal, weak...

Messenger RNA processing in Methanocaldococcus (Methanococcus) jannaschii (2009)

Zhang, Jian, Olsen, Gary J.

Messenger RNA (mRNA) processing plays important roles in gene expression in all domains of life. A number of cases of mRNA cleavage have been documented in Archaea, but available data are...

Ionic Liquids as Precursors for Nitrogen-Doped Graphitic Carbon (2009)

Paraknowitsch, Jens Peter, Zhang, Jian, Su, Dang Sheng, Thomas, Arne, Antonietti, Markus

Nitrogen-doped carbons are prepared by thermolysis of two organic, nitrogen-rich ionic liquids (see figure). The nitrogen content can be adjusted by the thermolysis temperature. As the precursors are...

ODH @ CNTs – Metal-free Catalytic Alkane Activation (2009)

Frank, Benjamin, Zhang, Jian, Liu, Xi, Morassutto, M., Schomäcker, Richard, Schlögl, Robert, ...

The conversion of alkanes into higher valued olefins by oxidative dehydrogenation (ODH) using supported transition metal oxides is a topic of intense research, however, the yield of alkenes is still...

Clipping noise compensation for OFDMA systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

This paper presents an efficient low-complexity clipping noise compensation scheme for PAR reduced orthogonal frequency division multiple access (OFDMA) systems. Conventional clipping noise...

Clipping Noise Compensation for OFDMA Systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

This paper presents an efficient low-complexity clipping noise compensation scheme for PAR reduced orthogonal frequency division multiple access (OFDMA) systems. Conventional clipping noise...

Low-complexity estimation of CFO and frequency independent I/Q mismatch for OFDM systems (2009)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

CFO and I/Q mismatch could cause significant performance degradation to OFDM systems. Their estimation and compensation are generally difficult as they are entangled in the received signal. In this...

CONJUGATE GRADIENT (2008)

Jian Zhang

Conjugate direction methods are motivated by the desire to speed up the typically slow convergence of steepest descent while avoiding using Hessian. They are first invented and analyzed for the...

OPTIMALITY CONDITIONS FOR UNCONSTRAINED OPTIMIZATION Consisder optimization problems of the form (2008)

Jian Zhang

and for unconstrained optimization problems we have Ω = R n. The first question to ask is whether a solution exists for (P1), and it is answered by the well-known Weiertras theorem: if f is...

EXPECTATION MAXIMIZATION (2008)

Jian Zhang

The Expectation Maximization (EM) algorithm [1, 2] is one of the most widely used algorithms in statistics. Suppose we are given some observed data X and a model family parametrized by θ, and would...

INTRODUCTION TO COMPUTATION COMPLEXITY (2008)

Jian Zhang

“Informally, an algorithm is any well-defined computational procedure that takes some value, or set of values, as input and produces some value, or set of values, as output. An algorithm is thus a...

Graph Distances in the Data-Stream Model (2008)

Feigenbaum, Joan, Kannan, Sampth, Mcgregor, Andrew, Suri, Siddarth, Zhang, Jian

We explore problems related to computing graph distances in the data-stream model. The goal is to design algorithms that can process the edges of a graph in an arbitrary order given only a limited...

RBM19 is essential for preimplantation development in the mouse (2008)

Zhang, Jian, Tomasini, Amber J, Mayer, Alan N

Abstract Background RNA-binding motif protein 19 (RBM19, NCBI Accession # NP_083038) is a conserved nucleolar protein containing 6 conserved RNA recognition motifs. Its biochemical function is to...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

Global P, PP, and PKP wave microseisms observed from distant storms (2008)

Gerstoft, Peter, Shearer, Peter M., Harmon, Nick, Zhang, Jian

Microseisms are the continuous background vibrations of the Earth observed between earthquakes. Most microseism studies have focused on low frequency energy (0.05–0.5 Hz) propagating as surface...

NONDIFFERENTIABLE FUNCTION AND SUBGRADIENT (2008)

Jian Zhang

Generally speaking, the function f we want to minimize may not be differentiable everywhere. For example, consider the function f(x) = |x|, which is not differentiable at x = 0. The concept of...

SLICE SAMPLER AND GIBBS SAMPLER (2008)

Jian Zhang

The Metropolis-Hastings algorithm is a generic algorithm which does not require much information from the target distribution f, except that it is easy to compute f’s value (up to a multiplicative...

Reduced expression of N-Myc downstream-regulated gene 2 in human thyroid cancer (2008)

Zhao, Huadong, Zhang, Jian, Lu, Jianguo, He, Xianli, Chen, Changsheng, Li, Xiaojun, ...

Abstract Background NDRG 2 (N-Myc downstream-regulated gene 2) was initially cloned in our laboratory. Previous results have shown that NDRG 2 expressed differentially in normal and cancer tissues....

Some Two-Step Procedures for Variable Selection in High-Dimensional Linear Regression (2008)

Zhang, Jian, Jeng, Xinge Jessie, Liu, Han

We study the problem of high-dimensional variable selection via some two-step procedures. First we show that given some good initial estimator which is $\ell_{\infty}$-consistent but not necessarily...

Resistance Fluctuations in Composite Fermion State near Landau Level Filling Factor $\nu= 1/2$ in A Square Quantum Well (2008)

Zhang, Jian, Du, R. R., Simmons, J. A., Reno, J. L.

We have studied the magnetotransport near Landau level filling factor $\nu = 1/2$ in a GaAs-Al0.3Ga0.7As square quantum well (width 35 nm) in magnetic field up to 42 T and in a temperature range...

CONSTRAINED OPTIMIZATION (2008)

Jian Zhang

Here we introduce some basic concepts of constrained optimization and illustrate with very simple examples. More details can be found in [1] and other references. Consider the minimization problem of...

n (2008)

Jian Zhang, ˆθ Xn

The bootstrap, invented by Efron in 1979, is a method for estimating standard errors and computing confidence intervals. The Bootstrap Principle Let θ = T(F) be an interesting parameter of a...

Computing Diameter in the Streaming and (2008)

Sliding-window Models, Joan Feigenbaum, Sampath Kannan, Jian Zhang

Abstract We investigate the diameter problem in the streaming and slidingwindow models. We show that, for a stream of n points or a sliding window of size n, any exact algorithm for diameter requires...

Convex Sets (2008)

Jian Zhang

Convexity plays an important role in numerical optimization, even for non-convex optimization problems.

MARKOV CHAIN AND HIDDEN MARKOV MODEL (2008)

Jian Zhang

Markov chain and hidden Markov model are probably the simplest models which can be used to model sequential data, i.e. data samples which are not independent from each other. Markov Chain Let I be a...

Concept Chain Based Text Clustering (2008)

Shaoxu Song, Jian Zhang, Chunping Li

Abstract. Different from familiar clustering objects, text documents have sparse data spaces. A common way of representing a document is as a bag of its component words, but the semantic relations...

Graph Distances in the Streaming Model: The Value of Space * Joan Feigenbaum ## # Sampath Kannan $| | Andrew McGregor $k Siddharth Suri $** (2008)

Jian Zhang

Abstract We investigate the importance of space when solvingproblems based on graph distance in the streaming model. In this model, the input graph is presentedas a stream of edges in an arbitrary...

DESIGN, SYNTHESIS, AND CHARACTERIZATION OF NOVEL LIGANDS CONTAINING SEVEN-MEMBERED RING FOR THE SENSITIZATION OF NEAR-INFRARED EMITTING LANTHANIDE CATIONS IN COMPLEXES AND NANOCRYSTALS (2008)

Zhang, Jian

Near-infrared (NIR) emitting lanthanide cations have a great potential for practical applications such as fluoroimmunoassays, polymer-based optical signal amplifiers, active materials in lasers, and...

DESIGN, SYNTHESIS, AND CHARACTERIZATION OF NOVEL LIGANDS CONTAINING SEVEN-MEMBERED RING FOR THE SENSITIZATION OF NEAR-INFRARED EMITTING LANTHANIDE CATIONS IN COMPLEXES AND NANOCRYSTALS (2008)

Zhang, Jian

Near-infrared (NIR) emitting lanthanide cations have a great potential for practical applications such as fluoroimmunoassays, polymer-based optical signal amplifiers, active materials in lasers, and...

Metal Coupled Folding of Cys2His2 Zinc-Finger (2008)

Li, Wenfei, Zhang, Jian, Wang, Jun, Wang, Wei

Zinc-fingers, which widely exist in eukaryotic cell and play crucial roles in life processes, depend on the binding of zinc ion for their proper folding. To computationally study the zinc coupled...

Effects of interacting networks of cardiovascular risk genes on the risk of type 2 diabetes mellitus (the CODAM study) (2008)

Van Greevenbroek, Marleen MJ, Zhang, Jian, Kallen, Carla JH, Schiffers, Paul MH, Feskens, Edith JM, De Bruin, Tjerk WA

Abstract Background: Genetic dissection of complex diseases requires innovative approaches for identification of disease-predisposing genes. A well-known example of a human complex disease with a...

Learning English Syllabi cation for Words (2008)

Jian Zhang, Howard J. Hamilton

cation Rules) learning system, which learns English syllabi cation rules using a symbolic pattern recognition approach. LE-SR was tested on NTC2, a 20,000 English word pronouncing dictionary. The...

Application Resource Demand Phase Analysis and Prediction in Support of Dynamic Resource Provisioning (2008)

Jian Zhang, Mazin Yousif, Robert Carpenter, Renato J. Figueiredo

Profiling the execution phases of an application can lead to optimizing the utilization of the underlying resources. This is the thrust of this paper, which presents a novel system-level application...

Key Words (2008)

Jian Zhang, Martin Vingron, Margret R. Hoehe, Snps Unlinked, Snps Markov, Monte Carlo

The inference of haplotype pairs directly from unphased genotype data is a key step in the analysis of genetic variation in relation to disease and pharmacogenetically relevant traits. Most popular...

Abstract Gaussian Process Learning for Cyber-Attack Early Warning (2008)

Jian Zhang, Phillip Porras, Johannes Ullrich

Network security has been a serious concern for many years. For example, firewalls often record thousands of exploit attempts on a daily basis. Network administrators could benefit from information...

EE368 Final Project Report RGB Level Face Detection (2008)

Jian Zhang, Miao He, Jing Chen

In this work, we describe a 2-step algorithm based on skin toner mask and Support Vector Machine (SVM) for face detection in RGB images. Accurate face detection is demonstrated on 7 training pictures...

Scientometrics of big science: A case study of research in the Sloan Digital Sky Survey (2008)

Jian Zhang

Large-scale scientific projects have become a major impetus of scientific advances. But few studies have specifically analyzed how those projects bolster scientific research. We address this question...

Delineating the Citation Impact of Scientific Discoveries (2008)

Chaomei Chen, Jian Zhang

www.library.drexel.edu The following item is made available as a courtesy to scholars by the author(s) and Drexel University Library and may contain materials and content, including computer code and...

Monophyletic clustering and characterization of protein families (2008)

Jian Zhang, Zhiyuan Zhao, Jennifer Evershed, Guoying Li

A protein family contains sequences that are evolutionarily related. Generally, this is reflected by sequence similarity. There have been many attempts to organize the set of protein families into...

www.elsevier.com/locate/entcs Reducing Symmetries to Generate Easier SAT Instances 1 (2008)

Jian Zhang, Zhuo Huang

Finding countermodels is an effective way of disproving false conjectures. In first-order predicate logic, model finding is an undecidable problem. But if a finite model exists, it can be found by...

Effect of Lactobacillus acidophilussupernatants on body weight and leptin expression in rats (2008)

Sousa, Renato, Halper, Jaroslava, Zhang, Jian, Lewis, Stephen J, Li, Wan-I O

Abstract Background Lactobacillus extracts and supernatants have been used as probiotics in human and veterinary medicine for their ability to enhance wound healing and immunity. Previous data from...

On the $\ell_1-\ell_q$ Regularized Regression (2008)

Liu, Han, Zhang, Jian

In this paper we consider the problem of grouped variable selection in high-dimensional regression using $\ell_1-\ell_q$ regularization ($1\leq q \leq \infty$), which can be viewed as a natural...

To appear in Computational Linguistics and Chinese Language Processing Improving the Effectiveness of Information Retrieval with Clustering and Fusion (2008)

Jian Zhang, Ming Zhou, Jianfeng Gao, Jiaxing Wang

Fusion and clustering are two approaches to improving the effectiveness of information retrieval. In fusion, ranked lists are combined together by various means. The motivation is that different IR...

WIRELESS MESH NETWORKS MAC Scheduling Using Channel State Diversity for High-Throughput IEEE 802.11 Mesh Networks (2008)

Jian Zhang

The head-of-line blocking problem impairs the throughput of the hotspot nodes in multihop wireless mesh networks. FIFO scheduling in the current IEEE 802.11 MAC suffers from this problem when the...

On the Value of Pairwise Constraints in Classification and Consistency (2008)

Jian Zhang, Rong Yan

In this paper we consider the problem of classification in the presence of pairwise constraints, which consist of pairs of examples as well as a binary variable indicating whether they belong to the...

Abstract (2008)

Joshua Dillon, Guy Lebanon, Yi Mao, Jian Zhang

High dimensional structured data such as text and images is often poorly understood and misrepresented in statistical modeling. The standard histogram representation suffers from high variance and...

Link Quality and Signal-to-Noise Ratio in 802.11 WLAN with Fading: A Time-Series Analysis (2008)

Jian Zhang, Ivan Marsic

Abstract—It is known that for multipath fading channels individual points or average signal-to-noise ratio (SNR) alone do not adequately describe the wireless channel quality. This paper uses...

ABSTRACT Topic-conditioned Novelty Detection (2008)

Yiming Yang, Jian Zhang, Jaime Carbonell, Chun Jin

Automated detection of the first document reporting each new event in temporally-sequenced streams of documents is an open challenge. In this paper we propose a new approach which addresses this...

Persistent Pseudo-Clearance Problem in IEEE802.11 Mesh Networks and its Multicast Based Solutions (2008)

Jian Zhang, Yuanzhu Peter, Chen Ivan Marsic

Abstract — Wireless mesh networks are flexible solutions to extend services from wireless LANs. The current IEEE 802.11 Specification, however, needs to be modified in various ways to be a suitable...

Performance and Parameter Optimization of UWB RAKE Reception with Interchip Interference (2008)

Jian Zhang, Rodney A. Kennedy, Thushara D. Abhayapala

In this paper, performance and parameter optimization of RAKE reception for time-hopping Ultra Wideband (THUWB) systems is investigated when interchip interference (ICI) is taken into consideration....

Role of Pulses in Ultra Wideband Systems (2008)

Jian Zhang, Thushara D. Abhayapala, Rodney A. Kennedy

UWB pulses are the unique labels of UWB systems. This paper investigates the role of pulse systematically and highlights the central position of the pulse in UWB systems. Four system properties...

Robustness of Regularized Linear Classification Methods (2008)

In Text Categorization, Jian Zhang

Real-world applications often require the classi cation of documents under situations of small number of features, mis-labeled documents and rare positive examples. This paper investigates the...

Recent advances in asthma genetics (2008)

Zhang, Jian, Paré, Peter D, Sandford, Andrew J

Abstract There are over 100 genes that have been reported to be associated with asthma or related phenotypes. In 2006–2007 alone there were 53 novel candidate gene associations reported in the...

New Training Sequence Structure for Zero-Padded SC-FDE System in Presence of Carrier Frequency Offset (2008)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

Frequency Domain Equalization (FDE) is an attractive solution for wireless broadband transmission because of its strong capability in handling multipath environment. However, frequency domain channel...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

Brand experiential value scales for limited-service hotels (2008)

Zhang, Jian

The hospitality industry in the United States is transforming. There is an emerging class of American consumers eager to express themselves in their use of lodging products and services. The new...

Single-molecule studies on fluorescently labeled silver particles: Effects of particle size (2008)

Zhang, Jian, Fu, Yi, Chowdhury, Mustafa H., Lakowicz, Joseph R.

We studied the dependence of single-molecule fluorescence on the size of nearby metal particles. The silver particles were synthesized with average diameters of metal cores being 5, 20, 50, 70, and...

Real-time Pedestrian Detection Using a Boosted Multi-layer Classifier (2008)

Paisitkriangkrai, Sakrapee, Shen, Chunhua, Zhang, Jian

Techniques for detecting pedestrian in still images have attracted considerable research interests due to its wide applications such as video surveillance and intelligent transportation systems. In...

Real-time Pedestrian Detection Using a Boosted Multi-layer Classifier (2008)

Paisitkriangkrai, Sakrapee, Shen, Chunhua, Zhang, Jian

Techniques for detecting pedestrian in still images have attracted considerable research interests due to its wide applications such as video surveillance and intelligent transportation systems. In...

New Training Sequence Structure for Zero-Padded SC-FDE System in Presence of Carrier Frequency Offset (2008)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

Frequency Domain Equalization (FDE) is an attractive solution for wireless broadband transmission because of its strong capability in handling multipath environment. However, frequency domain channel...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

New Training Sequence Structure for Zero-Padded SC-FDE System in Presence of Carrier Frequency Offset (2008)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

Frequency Domain Equalization (FDE) is an attractive solution for wireless broadband transmission because of its strong capability in handling multipath environment. However, frequency domain channel...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

New Training Sequence Structure for Zero-Padded SC-FDE System in Presence of Carrier Frequency Offset (2008)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

Frequency Domain Equalization (FDE) is an attractive solution for wireless broadband transmission because of its strong capability in handling multipath environment. However, frequency domain channel...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

Surface-Modified Carbon Nanotubes Catalyze Oxidative Dehydrogenation of n-Butane (2008)

Zhang, Jian, Liu, Xi, Blume, Raoul, Zhang, Aihua, Schlögl, Robert, Su, Dang Sheng

Butenes and butadiene, which are useful intermediates for the synthesis of polymers and other compounds, are synthesized traditionally by oxidative dehydrogenation (ODH) of n-butane over complex...

Individual Fe-Co Alloy Nanoparticles on Carbon Nanotubes: Structural and Catalytic Properties (2008)

Zhang, Jian, Müller, Jens-Oliver, Zheng, Weiqing, Wang, Di, Su, Dang Sheng, Schlögl, Robert

We report the synthesis, characterization, and catalytic performance of Fe-Co alloy nanoparticles inside the tubular channel of carbon nanotubes. The homogeneous distributions of Fe and Co in the...

Facile synthesis of carbon nanotube/natural bentonite composites as a stable catalyst for styrene synthesis (2008)

Rinaldi, Ali, Zhang, Jian, Mizera, Jan, Girgsdies, Frank, Wang, Ning, Abd Hamid, Sharifah Bee, ...

Natural bentonite mineral, without any wet chemical treatment, was used directly to catalyze the growth of multi-wall CNTs and the produced CNTs/bentonite as an integrated composite stably catalyzed...

New Training Sequence Structure for Zero-Padded SC-FDE System in Presence of Carrier Frequency Offset (2008)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

Frequency Domain Equalization (FDE) is an attractive solution for wireless broadband transmission because of its strong capability in handling multipath environment. However, frequency domain channel...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

New Training Sequence Structure for Zero-Padded SC-FDE System in Presence of Carrier Frequency Offset (2008)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

Frequency Domain Equalization (FDE) is an attractive solution for wireless broadband transmission because of its strong capability in handling multipath environment. However, frequency domain channel...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

On the ℓ1-ℓq Regularized Regression (2008)

Han Liu, Jian Zhang

In this paper we consider the problem of grouped variable selection in high-dimensional regression using ℓ1-ℓq regularization (1 ≤ q ≤ ∞), which can be viewed as a natural generalization of...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

New Training Sequence Structure for Zero-Padded SC-FDE System in Presence of Carrier Frequency Offset (2008)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

Frequency Domain Equalization (FDE) is an attractive solution for wireless broadband transmission because of its strong capability in handling multipath environment. However, frequency domain channel...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

An N-Dimensional Pseudo-Hilbert Scan for Arbitrarily-Sized Hypercuboids (2008)

ZHANG, Jian, KAMATA, Sei-ichiro

The N-dimensional (N-D) Hilbert curve is a one-to-one mapping between N-D space and one-dimensional (1-D) space. It is studied actively in the area of digital image processing as a scan technique...

Estimating the false discovery rate using the stochastic approximation algorithm (2008)

Liang, Faming, Zhang, Jian

Testing of multiple hypotheses involves statistics that are strongly dependent in some applications, but most work on this subject is based on the assumption of independence. We propose a new method...

Reduced-Rank Shift-Invariant Technique and Its Application for Synchronization and Channel Identification in UWB Systems (2008)

Jian (Andrew) Zhang, Rodney A. Kennedy, Thushara D. Abhayapala

We investigate reduced-rank shift-invariant technique and its application for synchronization and channel identification in UWB systems. Shift-invariant techniques, such as ESPRIT and the matrix...

N-Myc downstream-regulated gene 2 is involved in p53-mediated apoptosis (2008)

Liu, Na, Wang, Lifeng, Li, Xia, Yang, Qi, Liu, Xinping, Zhang, Jing, ...

The tumor suppressor, p53, is a transcription factor which can modulate the transcription of a number of target genes that are involved in cell-cycle arrest and apoptosis. However, the apoptotic...

Residues on the Dimer Interface of SARS Coronavirus 3C-like Protease: Dimer Stability Characterization and Enzyme Catalytic Activity Analysis (2008)

Chen, Shuai, Zhang, Jian, Hu, Tiancen, Chen, Kaixian, Jiang, Hualiang, Shen, Xu

3C-like protease (3CLpro) plays pivotal roles in the life cycle of severe acute respiratory syndrome coronavirus (SARS-CoV) and only the dimeric protease is proposed as the functional form. Guided by...

Visualization of various supramolecular assemblies of oligo(para-phenylenevinylene)-melamine and perylene bisimide (2008)

Zhang, Jian, Lee, Cameron C, Pouderoijen, Maarten J, Wolffs, Martin, Würthner, Frank, ...

A melamine derivative has been covalently equipped with two oligo(para-phenylenevinylene) (OPV) chromophores. This procedure yields a bifunctional molecule with two hydrogen-bonding arrays available...

New Training Sequence Structure for Zero-Padded SC-FDE System in Presence of Carrier Frequency Offset (2008)

Chen, Ying, Zhang, Jian (Andrew), Jayalath, Dhammika

Frequency Domain Equalization (FDE) is an attractive solution for wireless broadband transmission because of its strong capability in handling multipath environment. However, frequency domain channel...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

Clipping Noise Compensation for OFDM Systems (2008)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

An efficient and low-complexity clipping estimation and compensation scheme is presented. With clipped signals estimated from two different signal sources and accurately dentified phase information,...

Threshold of Global Existence for 3-D Attractive Nonlinear Schrödinger Equations under Confined Potentials (2007)

Yiu-Chung Hon, Jian Zhang, Xu Zhou

. Based on a nonlinear critical index, a threshold of global existence on the L 2 -norm of initial data for 3-D attractive nonlinear Schrodinger equations under conned potentials is derived. For...

Showing the Independence of An Axiom for Temporal Intervals by Model Generation (2007)

Jian Zhang

3.54> r; \Phi stands for exclusive OR, i.e., exactly one of the alternatives must hold. Ladkin [4] claimed that the last axiom is dependent on the first three axioms. Galton [3] disproved this by...

DOI: 10.1093/nar/gkg040 The Protein Information Resource (2007)

Cathy H. Wu, Hongzhan Huang, Leslie Arminski, Jorge Castro-alvear, Yongxing Chen, ...

The Protein Information Resource (PIR) is an integrated public resource of protein informatics that supports genomic and proteomic research and scientific discovery. PIR maintains the Protein...

ABSTRACT Topic-conditioned Novelty Detection (2007)

Yiming Yang, Jian Zhang, Jaime Carbonell, Chun Jin

Automated detection of the first document reporting each new event in temporally-sequenced streams of documents is an open challenge. In this paper we propose a new approach which addresses this...

General Terms (2007)

Yiming Yang, Jian Zhang, Jaime Carbonell, Chun Jin

Automated detection of the first document reporting each new event in temporally-sequenced streams of documents is an open challenge. In this paper we propose a new approach which addresses this...

1 (2007)

Joan Feigenbaum, Sampath Kannan, Jian Zhang

Abstract. We investigate the diameter problem in the streaming and sliding-window models. We show that, for a stream of n points or a sliding window of size n, any exact algorithm for diameter...

Using the Version Space Algorithm (2007)

For English Graphemes, Howard J. Hamilton, Jian Zhang

We describe a technique for learning pronunciation rules based on the Version Space algorithm. In particular, we describe how to learn pronunciation rules for a representative subset of the English...

resource of functional annotation of proteins (2007)

Cathy H. Wu, Hongzhan Huang, Leslie Arminski, Jorge Castro-alvear, Yongxing Chen, Zhang-zhi Hu, ...

The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discovery. The PIR, in...

Sieve Empirical Likelihood Ratio Tests for Nonparametric Functions (2007)

Jianqing Fan And, Jianqing Fan, Jian Zhang

Generalized likelihood ratio statistics have been proposed in Fan, Zhang and Zhang (2001) as a generally applicable method for testing nonparametric hypotheses concerning about nonparametric...

Abstract (2007)

Joan Feigenbaum, Joan Feigenbaum, Siddharth Suri, Siddharth Suri, Sampath Kannan, Sampath Kannan, ...

We investigate the importance of space when solving problems based on graph distance in the streaming model. In this model, the input graph is presented as a stream of edges in an arbitrary order....

Crystal Structure Communications (2007)

Jian Zhang, Zhao-ji Li, Yi-hang Wen, Yao Kang

The title compound, [Cd(C6H4NO2)2(H2O)2]n, forms a onedimensional chain structure based on a Cd atom with approximate pentagonal bipyramidal coordination geometry and two nicotinate ligands in...

Characterization of Sleep in Zebrafish and Insomnia in Hypocretin Receptor Mutants (2007)

Tohei Yokogawa, Wilfredo Marin, Juliette Faraco, Guillaume Pézeron, Lior Appelbaum, Jian Zhang, ...

Sleep is a fundamental biological process conserved across the animal kingdom. The study of how sleep regulatory networks are conserved is needed to better understand sleep across evolution. We...

Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice (2007)

Zhang, Xulong, Zhang, Jian, Wang, Lihua, Wei, Haiming, Tian, Zhigang

Abstract Background Signal transducer and activator of transcription 3 (STAT3) is usually constitutively activated in a variety of malignancies. Therefore, STAT3 may be a promising target for...

Influence of supramolecular organization on energy transfer properties in chiral oligo(p-phenylene vinylene) porphyrin assemblies (2007)

Wolffs, Martin, Zhang, Jian, Leclere, Philippe, ...

A comparative study on oligo(p-phenylene vinylene) (OPV)-appended porphyrins containing all trans-vinylene (either hydrophilic or lipophilic) or amide linkages (lipophilic) is presented. The type of...

Analyzing the impact of Sloan Digital Sky Survey on astronomical literature: A multiple perspective approach (2007)

Zhang, Jian, Zhu, Weizhong, Chen, Yunan, Vogeley, Michael, Chen, Chaomei

As part of an ongoing and ambitious project to support scientific discoveries in astronomy, in particular based on the use of Sloan Digital Sky Survey data, this article addresses a number of...

Micro Injection Fuel/Air Premixer/Combustion (2007)

Zhang, Jian

Lean premixed (LP) combustion has become the dominant industrial approach to reduce NOx emissions. Homogeneous mixing of lean fuel and air mixtures prevents the presence of undesirable localized...

Micro Injection Fuel/Air Premixer/Combustion (2007)

Zhang, Jian

Lean premixed (LP) combustion has become the dominant industrial approach to reduce NOx emissions. Homogeneous mixing of lean fuel and air mixtures prevents the presence of undesirable localized...

Radiation Damping of Shallow Foundations on Nonlinear Soil Medium (2007)

Zhang, Jian, Tang, Yuchuan

The paper evaluates the radiation damping associated with shallow foundations sitting on linear or nonlinear soil medium. The study was motivated by the need to develop macroscopic foundation models...

Finite Element Modeling of Shallow Foundations on Nonlinear Soil Medium (2007)

Zhang, Jian, Tang, Yuchuan

This paper investigates the dynamic response of shallow foundations on linear and nonlinear soil medium using finite element method. The study was motivated by the need to develop macroscopic...

Precision-seismology studies of inner core rotation and seismotectonics using correlated earthquake signals (2007)

Zhang, Jian

Earthquakes that generate similar (correlated) waveforms at common stations can be used to detect inner core motion and to relocate earthquakes in high precision. In the first chapter, I have...

Frequency Offset Estimation for OFDM Systems in the Presence of I/Q Mismatch (2007)

Chen, Ying, Jayalath, Dhammika, Zhang, Jian, Pollock, Tony

It is well known that Orthogonal Frequency Division Multiplexing (OFDM) systems are sensitive to carrier frequency offset (CFO), hence frequency offset estimation and compensation is critical in OFDM...

Complexity Adaptive OFDM Systems (2007)

Zhang, Jian, Chen, Ying, Jayalath, Dhammika

One disadvantage with current OFDM systems is, the system complexity associated with FFT module, equaliser, etc. is almost fixed and varies little with information bit rate. In this paper, based on...

Loss function approaches to predict a spatial quantile and its exceedance region (2007)

Zhang, Jian

An important problem in spatial statistics is to predict a spatial quantile and its associated exceedance region. This has applications in environmental sciences, natural resources, and agriculture,...

Simple Preparation of Honeycomb-like Macrostructured and Microporous Carbons with High Performance in Oxidative Dehydrogenation of Ethylbenzene (2007)

Wang, Lifeng, Zhang, Jian, Su, Dang Sheng, Ji, Yanyan, Cao, Xuejing, Xiao, Feng-Shou

Honeycomb-like macrostructured carbons with well-defined microporosity have been prepared from the microwave popping of maize followed by thermal carbonization. The obtained carbon material shows...

Learning-Based Anomaly Detection in BGP Updates (2007)

Zhang, Jian, Rexford, Jennifer, Feigenbaum, Joan

We propose an instance-learning based framework for detecting BGP routing anomalies. By using a vector of quantified features to represent BGP updates, our framework can capture more complex features...

Commercial Fe- or Co-Containing Carbon Nanotubes as Catalysts for NH3 Decomposition (2007)

Zhang, Jian, Comotti, Massimiliano, Schüth, Ferdi, Schlögl, Robert, Su, Dang Sheng

Fresh commercial carbon nanotubes (CNTs) containing residual Co or Fe nanoparticles are highly active for NH3 decomposition while the microstructure of CNTs remains unchanged. The 10 catalysts are...

ZEOLITE THIN FILM-FIBER INTEGRATED OPTICAL SENSORS FOR HIGHLY SENSITIVE DETECTION OF CHEMICALS IN GAS AND LIQUID PHASES (2007)

ZHANG, JIAN

Abstract Quantitative measurement of trace amount of chemicals in gas and liquid phases often requires time-consuming laboratory sample preparation and sophisticated instruments that are inconvenient...

Monophyletic clustering and characterization of protein families (2007)

Zhang, Jian, Zhao, Zhiyuan, Evershed, Jennifer, Li, Guoying

A protein family contains sequences that are evolutionarily related. Generally, this is reflected by sequence similarity. There have been many attempts to organize the set of protein families into...

Frequency Offset Estimation for OFDM Systems in the Presence of I/Q Mismatch (2007)

Chen, Ying, Jayalath, Dhammika, Zhang, Jian, Pollock, Tony

It is well known that Orthogonal Frequency Division Multiplexing (OFDM) systems are sensitive to carrier frequency offset (CFO), hence frequency offset estimation and compensation is critical in OFDM...

Complexity Adaptive OFDM Systems (2007)

Zhang, Jian, Chen, Ying, Jayalath, Dhammika

One disadvantage with current OFDM systems is, the system complexity associated with FFT module, equaliser, etc. is almost fixed and varies little with information bit rate. In this paper, based on...

Frequency Offset Estimation for OFDM Systems in the Presence of I/Q Mismatch (2007)

Chen, Ying, Jayalath, Dhammika, Zhang, Jian, Pollock, Tony

It is well known that Orthogonal Frequency Division Multiplexing (OFDM) systems are sensitive to carrier frequency offset (CFO), hence frequency offset estimation and compensation is critical in OFDM...

Complexity Adaptive OFDM Systems (2007)

Zhang, Jian, Chen, Ying, Jayalath, Dhammika

One disadvantage with current OFDM systems is, the system complexity associated with FFT module, equaliser, etc. is almost fixed and varies little with information bit rate. In this paper, based on...

Frequency Offset Estimation for OFDM Systems in the Presence of I/Q Mismatch (2007)

Chen, Ying, Jayalath, Dhammika, Zhang, Jian, Pollock, Tony

It is well known that Orthogonal Frequency Division Multiplexing (OFDM) systems are sensitive to carrier frequency offset (CFO), hence frequency offset estimation and compensation is critical in OFDM...

Complexity Adaptive OFDM Systems (2007)

Zhang, Jian, Chen, Ying, Jayalath, Dhammika

One disadvantage with current OFDM systems is, the system complexity associated with FFT module, equaliser, etc. is almost fixed and varies little with information bit rate. In this paper, based on...

Frequency Offset Estimation for OFDM Systems in the Presence of I/Q Mismatch (2007)

Chen, Ying, Jayalath, Dhammika, Zhang, Jian, Pollock, Tony

It is well known that Orthogonal Frequency Division Multiplexing (OFDM) systems are sensitive to carrier frequency offset (CFO), hence frequency offset estimation and compensation is critical in OFDM...

Complexity Adaptive OFDM Systems (2007)

Zhang, Jian, Chen, Ying, Jayalath, Dhammika

One disadvantage with current OFDM systems is, the system complexity associated with FFT module, equaliser, etc. is almost fixed and varies little with information bit rate. In this paper, based on...

A Calibration method for (2007)

Jian Zhang

We discuss how to solve the integration problem using (deterministic) numerical methods.

The concept of Zhongguoren and the political identities of ethnic minority people in contemporary China. (2007)

Zhang, Jian

Source: Dissertation Abstracts International, Volume: 68-09, Section: A, page: 4056.

Frequency Offset Estimation for OFDM Systems in the Presence of I/Q Mismatch (2007)

Chen, Ying, Jayalath, Dhammika, Zhang, Jian, Pollock, Tony

It is well known that Orthogonal Frequency Division Multiplexing (OFDM) systems are sensitive to carrier frequency offset (CFO), hence frequency offset estimation and compensation is critical in OFDM...

Complexity Adaptive OFDM Systems (2007)

Zhang, Jian, Chen, Ying, Jayalath, Dhammika

One disadvantage with current OFDM systems is, the system complexity associated with FFT module, equaliser, etc. is almost fixed and varies little with information bit rate. In this paper, based on...

Sharp conditions of global existence for the generalized Davey-Stewartson system (2007)

Shu, Ji, Zhang, Jian

This paper discusses the generalized Davey–Stewartson system. By constructing a cross-constrained variational problem and so-called invariant manifolds of the evolution flow, we derive a sharp...

A Pseudo-Hilbert Scan for Arbitrarily-Sized Arrays (2007)

ZHANG, Jian, KAMATA, Sei-ichiro, UESHIGE, Yoshifumi

The 2-dimensional (2-D) Hilbert curve is a one-to-one mapping between 2-D space and one-dimensional (1-D) space. It is studied actively in the area of digital image processing as a scan technique...

Frequency Offset Estimation for OFDM Systems in the Presence of I/Q Mismatch (2007)

Chen, Ying, Jayalath, Dhammika, Zhang, Jian, Pollock, Tony

It is well known that Orthogonal Frequency Division Multiplexing (OFDM) systems are sensitive to carrier frequency offset (CFO), hence frequency offset estimation and compensation is critical in OFDM...

Complexity Adaptive OFDM Systems (2007)

Zhang, Jian, Chen, Ying, Jayalath, Dhammika

One disadvantage with current OFDM systems is, the system complexity associated with FFT module, equaliser, etc. is almost fixed and varies little with information bit rate. In this paper, based on...

Value of serum glycated albumin and high-sensitivity C-reactive protein levels in the prediction of presence of coronary artery disease in patients with type 2 diabetes (2006)

Pu, Li, Lu, Lin, Xu, Xue, Zhang, Rui, Zhang, Qi, Zhang, Jian, ...

Abstract Background Coronary artery disease (CAD) is a major vascular complication of diabetes mellitus and reveals high mortality. Up to 30% of diabetic patients with myocardial ischemia remain...

Structure-based discovery of inhibitors of the YycG histidine kinase: New chemical leads to combat Staphylococcus epidermidisinfections (2006)

Qin, Zhiqiang, Zhang, Jian, Xu, Bin, Chen, Lili, Wu, Yang, Yang, Xiaomei, ...

Abstract Background Coagulase-negative Staphylococcus epidermidis has become a major frequent cause of infections in relation to the use of implanted medical devices. The pathogenicity of S....

SYNTHESIS AND NEAR INFRARED LUMINESCENT PROPERTIES OF LANTHANIDE COMPLEXES (2006)

Zhang, Jian

In vivo near-infrared (NIR) fluorescence microscopy and imagery is an emerging research area in biology. Organic dyes currently tested for NIR imagery have very severe limitations such as rapid...

SYNTHESIS AND NEAR INFRARED LUMINESCENT PROPERTIES OF LANTHANIDE COMPLEXES (2006)

Zhang, Jian

In vivo near-infrared (NIR) fluorescence microscopy and imagery is an emerging research area in biology. Organic dyes currently tested for NIR imagery have very severe limitations such as rapid...

Efficiency gains from bank consolidations (1999--2005): Estimation by a profit function (2006)

Zhang, Jian

Efficiency gains from recent U.S. bank consolidations are evaluated in this study. Our analysis is based on the well-developed duality theory, according to which we can use a profit function to...

Multiband-OFDM UWB vs IEEE802.11n: System Level Design Considerations (2006)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

Both Multiband Orthogonal Frequency Division Multiplexing (MB-OFDM) Ultra Wideband (UWB) technology and Multiple-Input Multiple Output (MIMO)-OFDM technology have been proposed for future wireless...

Orbital stability of standing waves for a class of Schrödinger equations with unbounded potential (2006)

Jian Zhang, Yunyun Wei

This paper is concerned with the nonlinear Schrödinger equation with an unbounded potential i ϕ t = − Δ ϕ + V ( x ) ϕ − μ | ϕ | p...

Orbital stability of standing waves for a class of Schrödinger equations with unbounded potential (2006)

Guanggan Chen, Jian Zhang, Yunyun Wei

This paper is concerned with the nonlinear Schrödinger equation with an unbounded potential...

Efficiency gains from bank consolidations (1999-2005) [electronic resource] : estimation by a profit function / (2006)

Zhang, Jian.

Efficiency gains from recent U.S. bank consolidations are evaluated in this study. Our analysis is based on the well-developed duality theory, according to which we can use a profit function to...

Multiband-OFDM UWB vs IEEE802.11n: System Level Design Considerations (2006)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

Both Multiband Orthogonal Frequency Division Multiplexing (MB-OFDM) Ultra Wideband (UWB) technology and Multiple-Input Multiple Output (MIMO)-OFDM technology have been proposed for future wireless...

Multiband-OFDM UWB vs IEEE802.11n: System Level Design Considerations (2006)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

Both Multiband Orthogonal Frequency Division Multiplexing (MB-OFDM) Ultra Wideband (UWB) technology and Multiple-Input Multiple Output (MIMO)-OFDM technology have been proposed for future wireless...

Attenuation relations of strong ground motion in Japan using site classification based on predominant period (2006)

Zhao, John X, Zhang, Jian, Fukushima, Yasuhiro, Fukushima, Yoshimitsu, Asano, Akihiro, Ohno, Yuki, ...

A spectral acceleration attenuation model for Japan is presented in the present study. The data set includes a very large number of strong ground-motion records up to the 2003 Off Tokach main and...

An Empirical site-classification method for strong-motion stations in Japan using H/V response spectral ratio (2006)

Zhao, John X, Irikura, Kojiro, Zhang, Jian, Fukushima, Yoshimitsu, Somerville, Paul G, Asano, Akihiro, ...

Having a reliable site classification scheme is vital for the development of robust strong-motion attenuation models. We discuss a promising empirical site- classification scheme based on...

Multiband-OFDM UWB vs IEEE802.11n: System Level Design Considerations (2006)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

Both Multiband Orthogonal Frequency Division Multiplexing (MB-OFDM) Ultra Wideband (UWB) technology and Multiple-Input Multiple Output (MIMO)-OFDM technology have been proposed for future wireless...

Multiband-OFDM UWB vs IEEE802.11n: System Level Design Considerations (2006)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

Both Multiband Orthogonal Frequency Division Multiplexing (MB-OFDM) Ultra Wideband (UWB) technology and Multiple-Input Multiple Output (MIMO)-OFDM technology have been proposed for future wireless...

Learning Multiple Related Tasks using Latent (2006)

Independent Component Analysis, Jian Zhang, Zoubin Ghahramani, Yiming Yang

We propose a probabilistic model based on Independent Component Analysis for learning multiple related tasks. In our model the task parameters are assumed to be generated from independent sources...

Learning multiple related tasks using latent independent component analysis (2006)

Jian Zhang, Zoubin Ghahramani, Yiming Yang

We propose a probabilistic model based on Independent Component Analysis for learning multiple related tasks. In our model the task parameters are assumed to be generated from independent sources...

Adaptive MAC scheduling using channel state diversity for wireless networks (2006)

Jian Zhang, Yuanzhu Peter, Chen Ivan Marsic

Abstract—Head-of-line blocking problem compromises the throughput of multi-hop wireless networks. FIFO scheduling in the current IEEE802.11 MAC causes this problem when the network is highly...

Distributed File System Virtualization Techniques Supporting On-Demand Virtual Machine Environments for Grid (2006)

Ming Zhao, Jian Zhang, Renato J. Figueiredo

Abstract. This paper presents a data management solution which allows fast Virtual Machine (VM) instantiation and efficient run-time execution to support VMs as execution environments in Grid...

Contents (2006)

W. Ahrendt, P. Baumgartner, H. De Nivelle, Johan Bos, Simon Colton, Christian Fermüller, ...

Our field is called automated theorem proving because traditionally it has been concerned with the art of finding proofs automatically. In the beginning, researchers were motivated by the wish to...

Finding highly correlated pairs efficiently with powerful pruning (2006)

Jian Zhang

We consider the problem of finding highly correlated pairs in a large data set. That is, given a threshold not too small, we wish to report all the pairs of items (or binary attributes) whose...

Multiband-OFDM UWB vs IEEE802.11n: System Level Design Considerations (2006)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

Both Multiband Orthogonal Frequency Division Multiplexing (MB-OFDM) Ultra Wideband (UWB) technology and Multiple-Input Multiple Output (MIMO)-OFDM technology have been proposed for future wireless...

Orbital stability of standing waves for a class of Schrödinger equations with unbounded potential (2006)

Guanggan Chen, Jian Zhang, Yunyun Wei

This paper is concerned with the nonlinear Schrödinger equation with an unbounded potential iϕt=−Δϕ+V(x)ϕ−μ|ϕ|p−1ϕ−λ|ϕ|q−1ϕ, x∈ℝN, t≥0, where μ>0, λ>0, and 1

Significance of COX-2 expression in human esophageal squamous cell carcinoma (2006)

Zhi, Huiying, Wang, Lin, Zhang, Jian, Zhou, Chuannong, Ding, Fang, Luo, Aiping, ...

Cyclooxygenase-2 (COX-2) is well established to play an important role in the tumorigenesis of a variety of human cancers; however, the function of COX-2 in the development of esophageal squamous...

Self-Employment with Chinese Characteristics: The Forgotten Engine of Rural China's Growth (2006)

Zhang, Jian, Zhang, Linxiu, Rozelle, Scott, Boucher, Steve

This article sketches a picture of the self-employment sector in rural China and examines the nature of its emergence. Using a randomly selected, nationally representative household-level data set...

Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: Reverse docking, enzymatic assay, and X-ray crystallography validation (2006)

Cai, Jianhua, Han, Cong, Hu, Tiancen, Zhang, Jian, Wu, Dalei, Wang, Fangdao, ...

Colonization of human stomach by the bacterium Helicobacter pylori is a major causative factor for gastrointestinal illnesses and gastric cancer. However, the discovery of anti-H. pylori agents is a...

GAS41 interacts with transcription factor AP-2{beta} and stimulates AP-2{beta}-mediated transactivation (2006)

Ding, Xiaofeng, Fan, Changzheng, Zhou, Jianlin, Zhong, Yingli, Liu, Rushi, Ren, Kaiqun, ...

Transcription factor AP-2 regulates transcription of a number of genes involving mammalian development, differentiation and carcinogenesis. Recent studies have shown that interaction partners can...

Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: Reverse docking, enzymatic assay, and x-ray crystallography validation (2006)

Cai, Jianhua, Han, Cong, Hu, Tiancen, Zhang, Jian, Wu, Dalei, Wang, Fangdao, ...

Colonization of human stomach by the bacterium Helicobacter pylori is a major causative factor for gastrointestinal illnesses and gastric cancer. However, the discovery of anti-H. pylori agents is a...

Sharp conditions of global existence for the generalized Davey-Stewartson system (2006)

Shu, Ji, Zhang, Jian

This paper discusses the generalized Davey–Stewartson system. By constructing a cross-constrained variational problem and so-called invariant manifolds of the evolution flow, we derive a sharp...

The existence of CD11c+ sentinel and F4/80+ interstitial dendritic cells in dental pulp and their dynamics and functional properties (2006)

Zhang, Jian, Kawashima, Nobuyuki, Suda, Hideaki, Nakano, Yukiko, Takano, Yoshiro, Azuma, Miyuki

Dental caries and pulpitis are the most common bacterial infections in humans. However, the immune responses against bacterial stimulation in dental pulp that is bounded by special hard tissues are...

SELF-EMPLOYMENT WITH CHINESE CHARACTERISTICS: THE FORGOTTEN ENGINE OF RURAL CHINA'S GROWTH (2006)

Zhang, Jian, Zhang, Linxiu, Rozelle, Scott, Boucher, Steve

This article sketches a picture of the self-employment sector in rural China and examines the nature of its emergence. Using a randomly selected, nationally representative household-level data set...

Sharp threshold of global existence for non-linear Gross-Pitaevskii equation in RN (2006)

Chen, Guanggan, Zhang, Jian

This paper is concerned with the non-linear Gross–Pitaevskii equation which describes the attractive Bose–Einstein condensate under a magnetic trap. By an intricate variational argument we derive...

BioThesaurus: a web-based thesaurus of protein and gene names (2006)

Liu, Hongfang, Hu, Zhang-Zhi, Zhang, Jian, Wu, Cathy

BioThesaurus is a web-based system designed to map a comprehensive collection of protein and gene names to protein entries in the UniProt Knowledgebase. Currently covering more than two million...

Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: Reverse docking, enzymatic assay, and x-ray crystallography validation (2006)

Cai, Jianhua, Han, Cong, Hu, Tiancen, Zhang, Jian, Wu, Dalei, Wang, Fangdao, ...

Colonization of human stomach by the bacterium Helicobacter pylori is a major causative factor for gastrointestinal illnesses and gastric cancer. However, the discovery of anti-H. pylori agents is a...

Sharp conditions of global existence for the generalized Davey-Stewartson system (2006)

Shu, Ji, Zhang, Jian

This paper discusses the generalized Davey–Stewartson system. By constructing a cross-constrained variational problem and so-called invariant manifolds of the evolution flow, we derive a sharp...

Multiband-OFDM UWB vs IEEE802.11n: System Level Design Considerations (2006)

Chen, Ying, Zhang, Jian, Jayalath, Dhammika

Both Multiband Orthogonal Frequency Division Multiplexing (MB-OFDM) Ultra Wideband (UWB) technology and Multiple-Input Multiple Output (MIMO)-OFDM technology have been proposed for future wireless...

On Graph Problems in a Semi-Streaming Model (2005)

Feigenbaum, Joan, Kannan, Sampath, McGregor, Andrew, Suri, Siddharth, Zhang, Jian

We formalize a potentially rich new streaming model, the semi-streaming model, that we believe is necessary for the fruitful study of efficient algorithms for solving problems on massive graphs whose...

Vortex Lattice in the Planar Bose-Einstein Condensates with Dipolar Interactions (2005)

Zhang, Jian, Zhai, Hui

In this letter we investigate the effects of dipole-dipole interactions on the vortex lattices in fast rotating Bose-Einstein condensates. For single planar condensate, we show that the triangular...

Adaptive genetic algorithm and quasi-parallel genetic algorithm : application to knapsack problem (2005)

Szeto, Kwok-Yip, Zhang, Jian

A new adaptive genetic algorithm using mutation matrix is introduced and implemented in a single computer using the quasi-parallel time sharing algorithm for the solution of the zero/one knapsack...

Pairing between Atoms and Molecules in a Boson-Fermion Resonant Mixture (2005)

Zhang, Jian, Zhai, Hui

We consider a mixture of fermionic and bosonic atoms nearby interspecies Feshbach resonances, which have been observed recently in $^6$Li-$^{23}$Na mixture by MIT group, and in $^{40}$K-$^{87}$Rb...

Sieve empirical likelihood ratio tests for nonparametric functions (2005)

Fan, Jianqing, Zhang, Jian

Generalized likelihood ratio statistics have been proposed in Fan, Zhang and Zhang [Ann. Statist. 29 (2001) 153-193] as a generally applicable method for testing nonparametric hypotheses about...

An immunocompromised BALB/c mouse model for respiratory syncytial virus infection (2005)

Kong, Xiaoyuan, Hellermann, Gary R, Patton, Geoff, Kumar, Mukesh, Behera, Aruna, Randall, Timothy S, ...

Abstract Background Respiratory syncytial virus (RSV) infection causes bronchiolitis in infants and children, which can be fatal, especially in immunocompromised patients. The BALB/c mouse, currently...

Detection of TP53 mutation using a portable Surface Plasmon Resonance DNA-based biosensor (2005)

Jiang, Tieshan, Minunni, Maria, Wilson, P. K., Zhang, Jian, Turner, Anthony P. F., Mascini, Marco

A DNA-based Surface Plasmon Resonance (SPR) biosensor has been developed for the detection of TP53 mutation using the inexpensive and commercially available instrument, SPREETATM SPR-EVM-BT, from...

Implementing Value-Transparency in supply relations (2005)

Lamming, Richard, Zhang, Jian, Caldwell, Nigel, Phillips, Wendy

Purpose - To explore and identify the strategic approaches firms may follow in their pursuit of value transparency (VT) in inter-organisational relations in supply networks....

A Probabilistic Model for Online Document Clustering with Application to Novelty Detection (2005)

Zhang, Jian, Ghahramani, Zoubin, Yang, Yiming

In this paper we propose a probabilistic model for online document clustering. We use non-parametric Dirichlet process prior to model the growing number of clusters, and use a prior of general...

Haplotype reconstruction for diploid populations (2005)

Zhang, Jian, Vingron, Martin, Hoehe, Margret R.

The inference of haplotype pairs directly from unphased genotype data is a key step in the analysis of genetic variation in relation to disease and pharmacogenetically relevant traits. Most popular...

Haplotype reconstruction for diploid populations (2005)

Zhang, Jian, Vingron, Martin, Hoehe, Margret R.

The inference of haplotype pairs directly from unphased genotype data is a key step in the analysis of genetic variation in relation to disease and pharmacogenetically relevant traits. Most popular...

Cramér-Rao Lower Bounds for the Synchronization of UWB Signals (2005)

Jian Zhang, Rodney A. Kennedy, Thushara D. Abhayapala

We present Cramér-Rao lower bounds (CRLBs) for the synchronization of UWB signals which should be tight lower bounds for the theoretical performance limits of UWB synchronizers. The CRLBs are...

Low HDL cholesterol is associated with suicide attempt among young healthy women: the Third National Health and Nutrition Examination Survey (2005)

Zhang, Jian, McKeown, Robert E., Hussey, James R., Thompson, Shirley J., Woods, John R., Ainsworth, Barbara E.

Background Serum cholesterol is reported to be associated with suicidality, but studies conducted among general healthy population are rare. We examined the association between serum cholesterol and...

Graph distances in the streaming model: the value of space (2005)

Joan Feigenbaum, Sampath Kannan, Andrew Mcgregor, Siddharth Suri, Jian Zhang

We investigate the importance of space when solving problems based on graph distance in the streaming model. In this model, the input graph is presented as a stream of edges in an arbitrary order....

Massive Data Streams in Graph Theory and Computational Geometry (2005)

Jian Zhang

Streaming is an important paradigm for handling data sets that are too large to fit in main memory. In the streaming computational model, algorithms are restricted to using much less space than they...

A Smoothed Boosting Algorithm Using Probabilistic Output Codes (2005)

Rong Jin, Jian Zhang

AdaBoost.OC has shown to be an e#ective method in boosting "weak" binary classifiers for multi-class learning. It employs the Error Correcting Output Code (ECOC) method to convert a...

Learning Multiple Related Tasks Using Latent Independent Component Analysis (2005)

Jian Zhang, Jian Zhangý, Yiming Yang, Zoubin Ghahramani, Yiming Yangý

We propose a probabilistic model based on Independent Component Analysis for learning multiple related tasks. In our model the task parameters are assumed to be generated from independent sources...

Robustness of adaptive filtering methods in a cross-benchmark evaluation (2005)

Yiming Yang, Shinjae Yoo, Jian Zhang, Bryan Kisiel

This paper reports a cross-benchmark evaluation of regularized logistic regression (LR) and incremental Rocchio for adaptive filtering. Using four corpora from the Topic Detection and Tracking (TDT)...

Robustness of adaptive filtering methods in a cross-benchmark evaluation (2005)

Yiming Yang, Shinjae Yoo, Jian Zhang, Bryan Kisiel

This paper reports a cross-benchmark evaluation of regularized logistic regression (LR) and incremental Rocchio for adaptive filtering. Using four corpora from the Topic Detection and Tracking (TDT)...

A Smoothed Boosting Algorithm Using Probabilistic Output Codes (2005)

Rong Jin, Jian Zhang

AdaBoost.OC has shown to be an effective method in boosting “weak ” binary classifiers for multi-class learning. It employs the Error Correcting Output Code (ECOC) method to convert a multi-class...

Learning-Based Anomaly Detection in BGP Updates (2005)

Jian Zhang

Detecting anomalous BGP-route advertisements is crucial for improving the security and robustness of the Internet’s interdomain-routing system. In this paper, we propose an instance-learning...

Zeolite 4A and zeolite 5A manufacturing process simulation and optimization / (2005)

Zhang, Jian.

Thesis (M.S.)--University of New Hampshire (Dept. of Chemical Engineering), 2005.

Cramér-Rao Lower Bounds for the Synchronization of UWB Signals (2005)

Jian Zhang, Rodney A. Kennedy, Thushara D. Abhayapala

We present Cramér-Rao lower bounds (CRLBs) for the synchronization of UWB signals which should be tight lower bounds for the theoretical performance limits of UWB synchronizers. The CRLBs are...

Sharp threshold of global existence for non-linear Gross-Pitaevskii equation in RN (2005)

Chen, Guanggan, Zhang, Jian

This paper is concerned with the non-linear Gross-Pitaevskii equation which describes the attractive Bose-Einstein condensate under a magnetic trap. By an intricate variational argument we derive out...

Significance of COX-2 expression in human esophageal squamous cell carcinoma (2005)

Zhi, Huiying, Wang, Lin, Zhang, Jian, Zhou, Chunnong, Ding, Fang, Luo, Aiping, ...

Cyclooxygenase-2 (COX-2) is well established to play an important role in the tumorigenesis of a variety of human cancers; however, the function of COX-2 in the development of esophageal squamous...

Association of Serum Cholesterol and History of School Suspension among School-age Children and Adolescents in the United States (2005)

Zhang, Jian, Muldoon, Matthew F., McKeown, Robert E., Cuffe, Steven P.

The dietary guidelines developed for adults have been extended to children, but the role of serum cholesterol in the neurodevelopment of children is poorly understood. In the Third National Health...

BioThesaurus: a web-based thesaurus of protein and gene names (2005)

Liu, Hongfang, Hu, Zhang-Zhi, Zhang, Jian, Wu, Cathy

BioThesaurus is a web-based system designed to map a comprehensive collection of protein and gene names to protein entries in the UniProt Knowledgebase. Currently covering more than two million...

The effect of osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft (2004)

Kiefer, J. A., Vessella, Robert L., Quinn, Janna E., Odman, Austin M., Zhang, Jian, Keller, Evan T., ...

Osteoprotegerin (OPG) plays a central role in controlling bone resorption. Exogenous administration of OPG has been shown to be effective in preventing osteolysis and limiting the growth of...

Osteoblasts induce prostate cancer proliferation and PSA expression through interleukin-6-mediated activation of the androgen receptor (2004)

Lu, Yi, Zhang, Jian, Dai, Jinlu, Dehne, Lindsay A., Mizokami, Atsushi, Yao, Zhi, ...

Prostate cancer (CaP) metastases selectively develop in bone as opposed to other sites through unknown mechanisms. Interleukin-6 (IL-6) is considered to contribute to CaP progression and is produced...

Sieve empirical likelihood ratio tests for nonparametric functions (2004)

Fan, Jianqing, Zhang, Jian

Generalized likelihood ratio statistics have been proposed in Fan, Zhang and Zhang [Ann. Statist. 29 (2001) 153–193] as a generally applicable method for testing nonparametric hypotheses about...

In vivo real-time imaging of TGF-Β-induced transcriptional activation of the RANK ligand gene promoter in intraosseous prostate cancer (2004)

Zhang, Jian, Lu, Yi, Dai, Jinlu, Yao, Zhi, Kitazawa, Riko, Kitazawa, Sohei, ...

BACKGROUND Current animal models of prostate cancer (CaP) bone metastasis do not allow measurement of either tumor growth in bone over time or activation of gene promoters in intraosseous tumors. To...

Febre catarral maligna em bovinos no Rio Grande do Sul: transmissão experimental para bovinos e caracterização do agente etiológico (2004)

Garmatz,Shana L., Irigoyen,Luiz F., Rech,Raquel R., Brown,Corrie C., Zhang,Jian, Barros,Claudio S. L.

São relatados dois surtos de febre catarral maligna (FCM) em bovinos de duas propriedades rurais (A e B) do município de Santiago, Rio Grande do Sul (RS), a transmissão da doença a bovinos...

Three-dimensional crustal structure in central Taiwan from gravity inversion with a parallel genetic algorithm (2004)

Zhang, Jian, Wang, Chi-yuen, Shi, Yaolin, Cai, Yongen, Chi, Wu-Cheng, Dreger, Douglas, ...

Genetic algorithm (GA) is combined with finite-element method for the first time as an alternative method to invert gravity anomaly data for reconstructing the 3D density structure in the subsurface....

Structural Characterization of Modern Highway Overcrossings - Case Study (2004)

Zhang, Jian, Makris, Nicos, Delis, Tim

This paper revisits the mechanical characterization of the main substructure elements of highway overcrossings in an effort to build a more balanced methodology to compute the earthquake response of...

Seismic Response Analysis of a Highway Overcrossing Equipped with Elastomeric Bearings and Fluid Dampers (2004)

Makris, Nicos, Zhang, Jian

This paper presents a case study on the seismic response of a recently constructed freeway overcrossing located in southern California, which is equipped with elastomeric bearings and fluid dampers...

Probabilistic Score Estimation with Piecewise Logistic Regression (2004)

Jian Zhang, Yiming Yang

Well-calibrated probabilities are necessary in many applications like probabilistic frameworks or cost-sensitive tasks. Based on previous success of asymmetric Laplace method in calibrating text...

On graph problems in a semi-streaming model (2004)

Joan Feigenbaum, Sampath Kannan, Andrew Mcgregor, Jian Zhang

Abstract. We formalize a potentially rich new streaming model, the semi-streaming model, that we believe is necessary for the fruitful study of efficient algorithms for solving problems on massive...

Improving first-order model searching by propositional reasoning and lemma learning (2004)

Zhuo Huang, Hantao Zhang, Jian Zhang

Abstract. The finite model generation problem in the first-order logic is a generalization of the propositional satisfiability (SAT) problem. An essential algorithm for solving the problem is...

On graph problems in a semi-streaming model (2004)

Joan Feigenbaum, Sampath Kannan, Andrew Mcgregor, Jian Zhang

Abstract. We formalize a potentially rich new streaming model, the semi-streaming model, that we believe is necessary for the fruitful study of ecient algorithms for solving problems on massive...

A Discriminative Learning Framework with Pairwise Constraints for Video Object Classification (2004)

Rong Yan, Jian Zhang, Jie Yang, Alexander Hauptmann, Er Hauptmann

In video object classification, insufficient labeled data may at times be easily augmented with pairwise constraints on sample points, i.e, whether they are in the same class or not. In this paper,...

PIRSF: family classification system at the Protein Information Resource (2004)

Cathy H. Wu, Anastasia Nikolskaya, Hongzhan Huang, Darren A. Natale, C. R. Vinayaka, ...

The Protein Information Resource (PIR) is an integrated public resource of protein informatics. To facilitate the sensible propagation and standardization of protein annotation and the systematic...

Rank Reduced ESPRIT Techniques in the Estimation of Principle Signal Components (2004)

Jian Zhang, Rodney A. Kennedy, Thushara D. Abhayapala

In this paper, we present novel rank reduced ESPRIT algorithms to estimate principle signal components with low computational complexity, which can typically be applied in the high resolution...

A probabilistic model for online document clustering with application to novelty detection (2004)

Jian Zhang, Zoubin Ghahramani, Yiming Yang

In this paper we propose a probabilistic model for online document clustering. We use non-parametric Dirichlet process prior to model the growing number of clusters, and use a prior of general...

A Discriminative Learning Framework with Pairwise Constraints for Video Object Classification (2004)

Rong Yan, Student Member, Jian Zhang, Jie Yang, Er G. Hauptmann

Abstract—To deal with the problem of insufficient labeled data in video object classification, one solution is to utilize additional pairwise constraints that indicate the relationship between two...

A probabilistic model for online document clustering with application to novelty detection (2004)

Jian Zhang, Zoubin Ghahramani, Yiming Yang

In this paper we propose a probabilistic model for online document clustering. We use non-parametric Dirichlet process prior to model the growing number of clusters, and use a prior of general...

Distributed File System Support for Virtual Machines in Grid Computing (2004)

Ming Zhao, Jian Zhang, Renato Figueiredo

This paper presents a data management solution which allows fast Virtual Machine (VM) instantiation and efficient run-time execution to support VMs as execution environments in Grid computing. It is...

A Discriminative Learning Framework with Pairwise Constraints for Video Object Classification (2004)

Rong Yan, Jian Zhang, Jie Yang, Er Hauptmann

In video object classification, insufficient labeled data may at times be easily augmented with pairwise constraints on sample points, i.e, whether they are in the same class or not. In this paper,...

VMPlants: Providing and Managing Virtual Machine Execution Environments for Grid Computing (2004)

Ivan Krsul, Arijit Ganguly, Jian Zhang, Renato J. Figueiredo

Virtual machines provide flexible, powerful execution environments for Grid computing, offering isolation and security mechanisms complementary to operating systems, customization and encapsulation...

Distributed File System Support for Virtual Machines in Grid Computing (2004)

Ming Zhao, Jian Zhang, Renato Figueiredo

This paper presents a data management solution which allows fast Virtual Machine (VM) instantiation and efficient run-time execution to support VMs as execution environments in Grid computing. It is...

VMPlants: Providing and Managing Virtual Machine Execution Environments for Grid Computing (2004)

Ivan Krsul, Arijit Ganguly, Jian Zhang, Renato J. Figueiredo

Virtual machines provide flexible, powerful execution environments for Grid computing, offering isolation and security mechanisms complementary to operating systems, customization and encapsulation...

A probabilistic model for online document clustering with application to novelty detection (2004)

Jian Zhang, Zoubin Ghahramani, Yiming Yang

In this paper we propose a probabilistic model for online document clustering. We use non-parametric Dirichlet process prior to model the growing number of clusters, and use a prior of general...

Evolution (2004)

Xiaohui Yuan, Jian Zhang, Bill P. Buckles

strategies based image registration via feature matching

Genetics of commitment to cell division in S. cerevisiae / (2004)

Zhang, Jian.

Thesis (Ph.D.)--Texas Tech University Health Sciences Center, 2004.

Developing a new generation micro compo system / (2004)

Zhang, Jian.

Thesis (M. Sc. (SPD))--Nanyang Technological University, School of Mechanical and Production Engineering, 2004.

Empirical Garnet-Biotite-Plagioclase-Quartz (GBPQ) Geobarometry in Medium- to High-Grade Metapelites (2004)

WU, CHUN-MING, ZHANG, JIAN, REN, LIU-DONG

On the basis of the net transfer reactions among garnet, biotite, plagioclase and quartz (for both Mg and Fe end-member models), the garnet–biotite–plagioclase–quartz (GBPQ) geobarometer was...

Superstructure in SmCo7 phase (2004)

Yu, Hong-Chun, Li, Jian-Qi, Bei, Yuan-Qian, Zhou, Yu-Qing, Zhang, Jian, Zhang, Wen-Yong, ...

We have performed a systematic investigation on the microstructural features of SmCo7−xCux(x = 0, 3.5) alloys. Transmission electron microscopy observations suggest that the SmCo7 is...

PIRSF: family classification system at the Protein Information Resource (2004)

Wu, Cathy H., Nikolskaya, Anastasia, Huang, Hongzhan, Yeh, Lai-Su L., Natale, Darren A., Vinayaka, C. R., ...

The Protein Information Resource (PIR) is an integrated public resource of protein informatics. To facilitate the sensible propagation and standardization of protein annotation and the systematic...

Separation of retinoid-induced epidermal and dermal thickening from skin irritation (2003)

Keller, Evan T., Aslam, Muhammad Nadeem, Varani, James, Fligiel, Helene, Dehne, Lindsay A., Lu, Yi, ...

The ability of the synthetic retinoid MDI-301, in which the carboxylic acid of 9- cis -retinoic acid (9-cis-RA) is replaced with an ester linkage, to induce epidermal and dermal thickening and skin...

Local polynomial fitting based on empirical likelihood (2003)

Zhang, Jian, Liu, Anna

A new nonparametric regression technique is proposed which involves the extension of local polynomial fitting to the empirical likelihood context, where the distribution of the stochastic error is...

The impact of trade-related investment measures in developing countries (2003)

Zhang, Jian

As foreign direct investment (FDI) grows rapidly in this highly integrated world, numerous new challenges confront the existing global trading system. Both developed countries and their developing...

CD4+CD25+immunoregulatory T cells may not be involved in controlling autoimmune arthritis (2003)

Bardos, Tamas, Czipri, Matyas, Vermes, Csaba, Finnegan, Alison, Mikecz, Katalin, Zhang, Jian

Abstract Accumulating evidence suggests that regulatory T cells play a crucial role in preventing autoimmunity. Recently, a naturally occurring CD4 + CD25 + T-cell subset that is anergic and also...

The effect of neighboring amino acid residues and solution environment on the oxidative stability of tyrosine in small peptides (2003)

Zhang, Jian

Tyrosine is susceptible to photo-oxidation and metal-catalyzed oxidation in aqueous solution. The effects of the physicochemical characteristics of the molecule and formulation variables on tyrosine...

Soft-materials: From colloids on templates to polymers in nematics (2003)

Zhang, Jian

We describe two major experimental studies on colloidal systems. We demonstrate that square two-dimensional grating templates can drive the growth of three-dimensional, face-centered-cubic (fcc)...

Models for non-intrusive estimation of wireless link bandwidth (2003)

Jian Zhang, Liang Cheng, Ivan Marsic

chengcse. lehigh. edu Abstract. Dynamics of link bandwidth of a wireless link, which changes frequently and abruptly due to the dynamic channel sharing, fading, and mobility, is of interest to...

A Scalability Analysis of Classifiers in Text Categorization (2003)

Yiming Yang, Jian Zhang, Bryan Kisiel

Real-world applications of text categorization often require a system to deal with tens of thousands of categories de- ned over a large taxonomy. This paper addresses the problem with respect to a...

Modified Logistic Regression: An Approximation to SVM and Its (2003)

Jian Zhang, Rong Jin, Yiming Yang, Alex G. Hauptmann

Logistic Regression (LR) has been widely used in statistics for many years, and has received extensive study in machine learning community recently due to its close relations to Support Vector...

Modified Logistic Regression: An Approximation to SVM and Its Applications in Large-Scale Text Categorization (2003)

Jian Zhang, Rong Jin, Yiming Yang, Alex Hauptmann

Logistic Regression (LR) has been widely used in statistics for many years, and has received extensive study in machine learning community recently due to its close relations to Support Vector...

Modified Logistic Regression: An Approximation to SVM and Its (2003)

Jian Zhang, Rong Jin, Yiming Yang, Alex G. Hauptmann

Logistic Regression (LR) has been widely used in statistics for many years, and has received extensive study in machine learning community recently due to its close relations to Support Vector...

Robustness of Regularized Linear Classification Methods in Text Categorization (2003)

Jian Zhang, Yiming Yang

Real-world applications often require the classi cation of documents under situations of small number of features, mis-labeled documents and rare positive examples. This paper investigates the...

A Scalability Analysis of Classifiers in Text Categorization (2003)

Yiming Yang Carnegie, Yiming Yang, Jian Zhang, Bryan Kisiel

Real-world applications of text categorization often require a system to deal with tens of thousands of categories defined over a large taxonomy. This paper addresses the problem with respect to a...

A faster iterative scaling algorithm for conditional exponential model (2003)

Rong Jin, Rong Yan, Jian Zhang, Alex G. Hauptmann

Conditional exponential model has been one of the widely used conditional models in machine learning field and improved iterative scaling (IIS) has been one of the major algorithms for finding the...

A Faster Iterative Scaling Algorithm For Conditional Exponential Model (2003)

Rong Jin, Rong Yan, Jian Zhang, Alex Hauptmann

Conditional exponential model has been one of the widely used conditional models in machine learning field and improved iterative scaling (IIS) has been one of the major algorithms for finding the...

The Protein Information Resource (2003)

Wu, Cathy H., Yeh, Lai-Su L., Huang, Hongzhan, Arminski, Leslie, Castro-Alvear, Jorge, Chen, Yongxing, ...

The Protein Information Resource (PIR) is an integrated public resource of protein informatics that supports genomic and proteomic research and scientific discovery. PIR maintains the Protein...

Expression and implications of tissue inhibitor of metalloproteinases-4 in mouse embryo (2003)

Zhang, Jian, Zhao, Yun-Ge, Cao, Yu-Jing, Sang, Qing-Xiang Amy, Duan, En-Kui

Matrix metalloproteinases (MMP), tissue inhibitors of metalloproteinases (TIMP), and MMP–TIMP interactions may contribute to the highly programmed process of embryo implantation. The loss of the...

LIGA Mold Insert Fabrication Using SU-8 Photoresist (2002)

Zhang, Jian

The LIGA process potentially enables economic mass-production of devices with high aspect ratio geometry. Central to the LIGA process is the fabrication of high quality LIGA molds. But in the...

LIGA Mold Insert Fabrication Using SU-8 Photoresist (2002)

Zhang, Jian

The LIGA process potentially enables economic mass-production of devices with high aspect ratio geometry. Central to the LIGA process is the fabrication of high quality LIGA molds. But in the...

Collagen-induced arthritis is exacerbated in IL-10-deficient mice (2002)

Finnegan, Alison, Kaplan, Charles D, Cao, Yanxia, Eibel, Hermann, Glant, Tibor T, Zhang, Jian

Abstract IL-10 is a potent immunoregulatory cytokine attenuating a wide range of immune effector and inflammatory responses. In the present study, we assess whether endogenous levels of IL-10...

Syncytiotrophoblast Is a Barrier to Maternal-Fetal Transmission of Herpes Simplex Virus1 (2002)

Hideki Koi, Jian Zhang, Antonis Makrigiannakis, Spiro Getsios, Colin D. MacCalman, ...

Herpes simplex virus (HSV)-1 has been discovered in placental tissue from spontaneous miscarriages, but reports of transplacental transmission and fetal infection are extremely rare. Previously, we...

Seismic Response Analysis of Highway Overcrossings Including Soil-Structure Interaction (2002)

Zhang, Jian, Makris, Nicos

This paper presents a systematic procedure for the seismic response analysis of highway overcrossings. The study employs an elementary stick model and a more sophisticated finite element formulation...

Kinematic Response Functions and Dynamic Stiffnesses of Bridge Embankments (2002)

Zhang, Jian, Makris, Nicos

Recognizing that soil-structure interaction affects appreciably the earthquake response of highway overcrossings, this paper compares approximate analytical solutions and finite element results to...

STABILIZATION/SOLIDIFICATION TREATMENT OF MERCURY CONTAINING WASTES USING REACTIVATED CARBON AND CEMENT (2002)

ZHANG, JIAN

This paper presents the study results for a novel stabilization/solidification (S/S) process for high mercury wastes (Hg > 260 ppm). A relatively low-cost powder reactivated carbon (PAC) was used to...

Stabilization/solidification treatment of mercury containing wastes using reactivated carbon and cement [electronic resource] / (2002)

Zhang, Jian., OhioLINK Electronic Theses And Dissertations Center.

This paper presents the study results for a novel stabilization/solidification (S/S) process for high mercury wastes (Hg> 260 ppm). A relatively low-cost powder reactivated carbon (PAC) was used to...

Computing Diameter in the Streaming and Sliding-Window Models (2002)

Joan Feigenbaum, Sampath Kannan, Jian Zhang

We investigate the diameter problem in the streaming and sliding-window models. We show that, for a stream of n points or a sliding window of size n, any exact algorithm for diameter requires Ω(n)...

Computing Diameter in the Streaming and Sliding-Window Models (2002)

Joan Feigenbaum, Sampath Kannan, Jian Zhang

We investigate the diameter problem in the streaming and sliding-window models. We show that, for a stream of n points or a sliding window of size n, any exact algorithm for diameter requires Ω(n)...

Analytical Description of Signal Characteristics and Interference for Time Hopped UWB System (2002)

Jian Zhang, Rodney A. Kennedy, Thushara D. Abhayapala

In this paper, signal and interference characterisation of Time Hopped Ultra Wideband (TH-UWB) systems is considered. Some special problems often neglected in theoretical studies are discussed, such...

The Protein Information Resource: an integrated public resource of functional annotation of proteins (2002)

Wu, Cathy H., Huang, Hongzhan, Arminski, Leslie, Castro-Alvear, Jorge, Chen, Yongxing, Hu, Zhang-Zhi, ...

The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discovery. The PIR, in...

Expression of matrix metalloproteinase-26 and tissue inhibitor of metalloproteinase-4 in human normal cytotrophoblast cells and a choriocarcinoma cell line, JEG-3 (2002)

Zhang, Jian, Cao, Yu-Jing, Zhao, Yun-Ge, Sang, Qing-Xiang Amy, Duan, En-Kui

The balance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) is critical for embryo implantation. Disturbance of this balance may lead to tumour...

Prostate Carcinoma Skeletal Metastases: Cross-talk between Tumor and Bone (2001)

Keller, Evan T., Zhang, Jian, Cooper, Carlton R., Smith, Peter C., McCauley, Laurie K., Pienta, Kenneth J., ...

The majority of men with progressive prostate cancer develop metastases with the skeleton being the most prevalent metastatic site. Unlike many other tumors that metastasize to bone and form...

Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro (2001)

Lin, Din-Lii, Tarnowski, Catherine P., Zhang, Jian, Dai, Jinlu, Rohn, Emileigh, Patel, Avni H., ...

BACKGROUND Prostate cancer frequently metastasizes to bone. However, unlike many other tumors that produce osteolytic lesions, prostate cancer produces osteoblastic lesions through unknown...

Structure and superconductivity of Mg(B1-xCx)2 compounds (2001)

Zhang, Shao-ying, Zhang, Jian, Zhao, Tong-yun, Rong, Chuan-bing, Shen, Bao-gen, Cheng, Zhao-hua

In this paper, we reported the structural properties and superconductivity of Mg(B1-xCx)2 compounds. Powder x-ray diffraction results indicate that the samples crystallize in a hexagonal AlB2-type...

Generalized Likelihood Ratio Statistics and Wilks Phenomenon (2001)

Fan, Jianqing, Zhang, Chunming, Zhang, Jian

Likelihood ratio theory has had tremendous success in parametric inference, due to the fundamental theory of Wilks. Yet, there is no general applicable approach for nonparametric inferences based on...

Rocking Response of Free-Standing Blocks Under Cycloidal Pulses (2001)

Zhang, Jian, Makris, Nicos

This paper examines in depth the transient rocking response of free-standing rigid blocks subjected to physically realizable trigonometric pulses. First, the expressions for the dynamic horizontal...

Rocking Response of Anchored Blocks Under Pulse-Type Motions (2001)

Makris, Nicos, Zhang, Jian

This paper examines the transient rocking response of anchored blocks subjected to physically realizable horizontal pulse-type motion. Restrainers with elastic-brittle and elastic-plastic behavior...

Transgenic Analysis of the Role of Transcription Factor AP-2 in Breast Development and Breast Cancer (2001)

Zhang, Jian

Proto-oncogene c-erbB-2 is overexpressed in 25-30% human breast cancers. Recently, in vitro studies have shown that transcription factor AP-2 proteins can bind to a critical region in the c-erbB-2...

ERP effects on modes, routes and departure time choice / (2001)

Zhang, Jian.

Thesis (M.Sc. (Tpt. Eng.))--Nanyang Technological University, School of Civil and Structural Engineering, 2001.

Linkage disequilibrium mapping by the decay of haplotype sharing in a founder population / (2001)

Zhang, Jian.

Thesis (Ph. D.)--University of Chicago, Dept. of Statistics, August 2001.

Jp2.6 Nids-Based Intermittent Diabatic Assimilation (2001)

And Application To, Donghai Wang, Kelvin K. Droegemeier, David Jahn, Ming Xue, ...

INTRODUCTION The lack of accurate moisture/cloud initial conditions is one of the major causes for the spinup problem in explicit cloud and precipitation forecasting models during the first a few...

CD28 co-stimulation restores T cell responsiveness in NOD mice by overcoming deficiencies in Rac-1/p38 mitogen-activated protein kinase signaling and IL-2 and IL-4 gene transcription (2001)

Zhang, Jian, Salojin, Konstantin V., Delovitch, Terry L.

Previously, we reported that T cell hyporesponsiveness induced by TCR ligation is causal to autoimmune diabetes in NOD mice. Neonatal CD28 co-stimulation reverses T cell hyporesponsiveness and...

IP multicast /--by Jian Zhang. (2000)

Zhang, Jian.

Thesis (M.S.)--California State University, Northridge, 2000.

Extraction of Chinese compound words: An experimental study on a very large corpus (2000)

Jian Zhang

This paper is to introduce a statistical method to extract Chinese compound words from a very large corpusL This method is based on mutual information and context dependency. Experimental results...

On the Use of Words and N-grams for Chinese Information Retrieval (2000)

Jian-yun Nie, Jiangfeng Gao, Jian Zhang, Ming Zhou

Abstract: In the processing of Chinese documents and queries in information retrieval (IR), one has to identify the units that are used as indexes. Words and n-grams have been used as indexes in...

Generalized Likelihood Ratio Statistics And Wilks Phenomenon (2000)

Jianqing Fan, Chunming Zhang, Jian Zhang

this paper. We introduce the generalized likelihood statistics to overcome the drawbacks of nonparametric maximum likelihood ratio statistics. New Wilks phenomenon is unveiled. We demonstrate that a...

On the Use of Words and N-grams for (2000)

Chinese Information Retrieval, Jiangfeng Gao, Jian Zhang, Ming Zhou

In the processing of Chinese documents and queries in information retrieval (IR), one has to identify the units that are used as indexes. Words and n-grams have been used as indexes in several...

Generalized Likelihood Ratio Statistics and Wilks Phenomenon (2000)

Jianqing Fan, Chunming Zhang, Jian Zhang

this paper. We introduce the generalized likelihood statistics to overcome the drawbacks of nonparametric maximum likelihood ratio statistics. New Wilks phenomenon is unveiled. We demonstrate that a...

Gain modulation of recurrent networks (2000)

Jian Zhang, L. F. Abbott

Gain modulation is an important mechanism by which attentional and other inputs modify the amplitude of neuronal responses without changing their selectivity. Gain modulation has been studied...

Sieve Likelihood Ratio Statistics and Wilks Phenomenon (1999)

Fan , Jianqing, Zhang, Chunming, Zhang, Jian

Maximum likelihood ratio theory contributes tremendous success to parametric inferences, due to the fundamental theory of Wilks (1938). Yet, there is no general applicable approach for nonparametric...

Thoughts on Milton's theodicy in Paradise Lost /--Jian (Patrick) Zhang. (1999)

Zhang, Jian (Patrick).

Master's essay (M.A.)--University of St. Thomas (Saint Paul, Minn.), 1999.

Error resilience for video coding services over packet-based networks (1999)

Zhang, Jian

Error resilience is an important issue when coded video data is transmitted over wired and wireless networks. Errors can be introduced by network congestion, mis-routing and channel noise. These...

Error resilience for video coding services over packet-based networks (1999)

Zhang, Jian

Error resilience is an important issue when coded video data is transmitted over wired and wireless networks. Errors can be introduced by network congestion, mis-routing and channel noise. These...

Error resilience for video coding services over packet-based networks (1999)

Zhang, Jian

Error resilience is an important issue when coded video data is transmitted over wired and wireless networks. Errors can be introduced by network congestion, mis-routing and channel noise. These...

Error resilience for video coding services over packet-based networks (1999)

Zhang, Jian

Error resilience is an important issue when coded video data is transmitted over wired and wireless networks. Errors can be introduced by network congestion, mis-routing and channel noise. These...

Error resilience for video coding services over packet-based networks (1999)

Zhang, Jian

Error resilience is an important issue when coded video data is transmitted over wired and wireless networks. Errors can be introduced by network congestion, mis-routing and channel noise. These...

Error resilience for video coding services over packet-based networks (1999)

Zhang, Jian

Error resilience is an important issue when coded video data is transmitted over wired and wireless networks. Errors can be introduced by network congestion, mis-routing and channel noise. These...

Error resilience for video coding services over packet-based networks (1999)

Zhang, Jian

Error resilience is an important issue when coded video data is transmitted over wired and wireless networks. Errors can be introduced by network congestion, mis-routing and channel noise. These...

The Computational Complexity of N-K Fitness Functions (1999)

Alden H. Wright, Richard K. Thompson, Jian Zhang

The N-K tness landscapes have been widely used as examples and test functions in the eld of evolutionary computation. Thus, the computational complexity of these landscapes as optimization problems...

Transgenic Analysis of the Role of Transcription Factor AP-2 in Breast Development and Breast Cancer. (1998)

Zhang, Jian

One of the most common alterations in human breast cancer is the overexpression of the c-erbB-2 proto-oncogene that occurs in 25-30% of human breast tumors. Recently, in vitro studies have shown that...

Evaluation of Cross-Correlation Methods on a Massive Scale for Accurate Relocation of Seismic Events (1998)

Kim, Won-Young, Richards, Paul G., Schaff, David P., Waldhauser, Felix, Zhang, Jian

Lamont-Doherty Earth Observatory (LDEO) at Columbia University is evaluating a method of locating seismic sources (earthquakes, explosions) based on the use of waveform cross-correlation (WCC)...

Breakdown properties of location $M$-estimators (1998)

Li, Guoying, Zhang, Jian

In this article, we consider the asymptotic behavior of three kinds of sample breakdown points. It is shown that for the location $M$-estimator with bounded objective function, both the addition...

Aalen's Linear Model for Sampled Risk Set Data: A Large Sample Study (1998)

Jian Zhang, Jian Zhang, Ørnulf Borgan, Rnulf Borgan

Borgan and Langholz (1997, Biometrics 53, 690-697) describe a method for estimating the parameter functions in Aalen's linear hazard regression model from sampled risk set data. Using a counting...

Transgenic Analysis of the Role of Transcription Factor AP-2 in Breast Development and Breast Cancer. (1997)

Zhang, Jian

One of the most alterations in human breast cancer is the overexpression of the c-erbB-2 protooncogene that has been shown to occur in 25-30% of human breast tumors. Recently this increased...

Medium Support in Mobile Computing (1997)

Jian Zhang

Just like in conventional desktop computing, medium support should also be provided in mobile computing. However, the medium support for mobile computing has a fundamental requirement: it should be...

Terminal {beta}-linked tyvelose creates unique epitopes in Trichinella spiralis glycan antigens (1997)

Ellis, Lauri A., McVay, Catherine S., Probert, Mark A., Zhang, Jian, Bundle, David R., Appleton, Judith A.

Indirect evidence that the immunodominant N-glycans of the parasite, Trichinella spiralis are capped by novel β-linked 3,6-dideoxy-D-arabinohexopyranosyl residues (tyvelase, Tyv) was obtained from...

Static electrification in large power transformers / (1996)

Zhang, Jian.

Thesis (M. Eng.)--Nanyang Technological University, School of Electrical and Electronic Engineering, 1996.

Evaporation and condensation in the transition regime of kinetic theory : a thesis / (1995)

Zhang, Jian.

Graduate School of Engineering, Dept. of Mechanical, Industrial and Manufacturing Engineering.

An Experimental Expert System For Routing Problems (1994)

Zhang, Jian

This paper describes an experimental system which provides heuristic solutions to vehicle routing problems. The system basically contains two components: an initial routes generator and a route...

Application of SGML and OODB Techniques In a Textual Database (1994)

Zhang, Jian

An electronic dictionary system (EDS) is developed using object-oriented database techniques based on ObjectStore. The EDS is basically composed of two parts: the Database Building Program (DBP), and...

Traffic assignment models with multiple user classes / (1994)

Zhang, Jian.

Thesis (Ph. D.)--University of Pennsylvania, 1994.

Genetic manipulation of barley. (1993)

Zhang, Jian.

Thesis (Ph. D.)--University of Nottingham, 1993.

An Abstract (1990)

Jian Zhang, Jian Zhang, Jennifer Rexford, Jennifer Rexford, Joan Feigenbaum, Joan Feigenbaum

We propose an instance-learning based framework for detecting BGP routing anomalies. By using a vector of quantified features to represent BGP updates, our framework can capture more complex features...

A Web-based Knowledge Aided Tutoring System for Vegetable Supply Chain (1970)

Hui Li, Zetian Fu, Yan Li, Jian Zhang

With the recent rapid progress of computer technology, researchers have attempted to adopt artificial intelligence and computer networks to develop computer-aided tutoring systems. Meanwhile, some...

c ○ 2008 Society for Industrial and Applied Mathematics GRAPH DISTANCES IN THE DATA-STREAM MODEL ∗ (1709)

Joan Feigenbaum, Sampath Kannan, Andrew Mcgregor, Siddharth Suri, Jian Zhang

Abstract. We explore problems related to computing graph distances in the data-stream model. The goal is to design algorithms that can process the edges of a graph in an arbitrary order given only a...

Assessing Climate Change Impacts: Agriculture

Francesco Bosello, Jian Zhang

The economy-wide implications of climate change on agricultural sectors in 2050 are estimated using a static computable general equilibrium model. Peculiar to this exercise is the coupling of the...

An Intertemporal Urban Economic Model with Natural Environment

Jian Zhang, Hiroyuki Shibusawa, Yuzuru Miyata

We are surely faced with the unavoidable problem as an element of important restrictions of development of human beings. It must be required to be solved immediately. It also brought the economic...

Environmental Taxation in Energy Sector - A Theoretical and Applied Analysis

Jian Zhang

A global multi-sectoral, multi-regional computational general equilibrium model is employed to assess carbon taxes under perfect competition and monopoly. We found that regional studies of carbon...

STABILIZATION/SOLIDIFICATION TREATMENT OF MERCURY CONTAINING WASTES USING REACTIVATED CARBON AND CEMENT

ZHANG, JIAN

This paper presents the study results for a novel stabilization/solidification (S/S) process for high mercury wastes (Hg > 260 ppm). A relatively low-cost powder reactivated carbon (PAC) was used to...

AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice

Nottoli, Timothy, Hagopian-Donaldson, Stephanie, Zhang, Jian, Perkins, Archibald, Williams, Trevor

The homozygous disruption of the mouse AP-2 gene yields a complex and lethal phenotype that results from defective development of the neural tube, head, and body wall. The severe and pleiotropic...

The Protein Information Resource: an integrated public resource of functional annotation of proteins

Wu, Cathy H., Huang, Hongzhan, Arminski, Leslie, Castro-Alvear, Jorge, Chen, Yongxing, Hu, Zhang-Zhi, ...

The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discovery. The PIR, in...

Identification of the enzymatic mechanism of nitroglycerin bioactivation

Chen, Zhiqiang, Zhang, Jian, Stamler, Jonathan S.

Nitroglycerin (glyceryl trinitrate, GTN), originally manufactured by Alfred Nobel, has been used to treat angina and heart failure for over 130 years. However, the molecular mechanism of GTN...

Collagen-induced arthritis is exacerbated in IL-10-deficient mice

Finnegan, Alison, Kaplan, Charles D, Cao, Yanxia, Eibel, Hermann, Glant, Tibor T, Zhang, Jian

IL-10 is a potent immunoregulatory cytokine attenuating a wide range of immune effector and inflammatory responses. In the present study, we assess whether endogenous levels of IL-10 function to...

CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis

Bardos, Tamas, Czipri, Matyas, Vermes, Csaba, Finnegan, Alison, Mikecz, Katalin, Zhang, Jian

Accumulating evidence suggests that regulatory T cells play a crucial role in preventing autoimmunity. Recently, a naturally occurring CD4+CD25+ T-cell subset that is anergic and also suppressive has...

The Protein Information Resource

Wu, Cathy H., Yeh, Lai-Su L., Huang, Hongzhan, Arminski, Leslie, Castro-Alvear, Jorge, Chen, Yongxing, ...

The Protein Information Resource (PIR) is an integrated public resource of protein informatics that supports genomic and proteomic research and scientific discovery. PIR maintains the Protein...

Osteoprotegerin inhibits prostate cancer–induced osteoclastogenesis and prevents prostate tumor growth in the bone

Zhang, Jian, Dai, Jinlu, Qi, Yinghua, Lin, Din-Lii, Smith, Peter, Strayhorn, Chris, ...

Prostate cancer (CaP) forms osteoblastic skeletal metastases with an underlying osteoclastic component. However, the importance of osteoclastogenesis in the development of CaP skeletal lesions is...

Divergence of Hoxc8 early enhancer parallels diverged axial morphologies between mammals and fishes

Anand, Sanjay, Wang, Wayne C. H., Powell, Dennis R., Bolanowski, Stacey A., Zhang, Jian, Ledje, Christina, ...

There is considerable interest in understanding how cis-regulatory modifications drive morphological changes across species. Because developmental regulatory genes, including Hox genes, are...

PIRSF: family classification system at the Protein Information Resource

Wu, Cathy H., Nikolskaya, Anastasia, Huang, Hongzhan, Yeh, Lai-Su L., Natale, Darren A., Vinayaka, C. R., ...

The Protein Information Resource (PIR) is an integrated public resource of protein informatics. To facilitate the sensible propagation and standardization of protein annotation and the systematic...

Chronic alcohol ingestion induces osteoclastogenesis and bone loss through IL-6 in mice

Dai, Jinlu, Lin, Dinlii, Zhang, Jian, Habib, Paula, Smith, Peter, Murtha, Jill, ...

To investigate the role of IL-6 in alcohol-mediated osteoporosis, we measured a variety of bone remodeling parameters in wild-type (il6+/+) or IL-6 gene knockout (il6–/–) mice that were fed...

Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells

Srivastava, Meera, Eidelman, Ofer, Zhang, Jian, Paweletz, Cloud, Caohuy, Hung, Yang, QingFeng, ...

Cystic fibrosis (CF) is a fatal, autosomal, recessive genetic disease that is characterized by profound lung inflammation. The inflammatory process is believed to be caused by massive overproduction...

RACK1 Regulates G1/S Progression by Suppressing Src Kinase Activity

Mamidipudi, Vidya, Zhang, Jian, Lee, Kelly C., Cartwright, Christine A.

Cancer genes exert their greatest influence on the cell cycle by targeting regulators of a critical checkpoint in late G1. Once cells pass this checkpoint, they are fated to replicate DNA and divide....

RecA-dependent mutants in Escherichia coli reveal strategies to avoid chromosomal fragmentation

Kouzminova, Elena A., Rotman, Ella, Macomber, Lee, Zhang, Jian, Kuzminov, Andrei

RecA- and RecBC-catalyzed repair in eubacteria assembles chromosomes fragmented by double-strand breaks. We propose that recA mutants, being unable to repair fragmented chromosomes, depend on various...

Growth Rate and Cell Size Modulate the Synthesis of, and Requirement for, G1-Phase Cyclins at Start

Schneider, Brandt L., Zhang, Jian, Markwardt, J., Tokiwa, George, Volpe, Tom, Honey, Sangeet, ...

In Saccharomyces cerevisiae, commitment to cell cycle progression occurs at Start. Progression past Start requires cell growth and protein synthesis, a minimum cell size, and G1-phase cyclins. We...

An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation

Chen, Zhiqiang, Foster, Matthew W., Zhang, Jian, Mao, Lan, Rockman, Howard A., Kawamoto, Toshihiro, ...

The identity of the cellular mechanisms through which nitroglycerin (glyceryl trinitrate, GTN) elicits nitric oxide (NO)-based signaling to dilate blood vessels remains one of the longest standing...

Regulation of RelB Expression during the Initiation of Dendritic Cell Differentiation

Cejas, Pedro J., Carlson, Louise M., Kolonias, Despina, Zhang, Jian, Lindner, Inna, Billadeau, Daniel D., ...

The transcription factor RelB is required for proper development and function of dendritic cells (DCs), and its expression is upregulated early during differentiation from a variety of progenitors....

A mouse model of elevated intraocular pressure: retina and optic nerve findings.

Gross, Ronald L, Ji, Jianzhong, Chang, Peter, Pennesi, Mark E, Yang, Zhuo, Zhang, Jian, ...

PURPOSE: To develop and characterize a mouse model of elevated intraocular pressure (IOP) as a means to investigate the underlying cellular and genetic mechanisms of glaucomatous optic neuropathy....

Clinical detection and movement recognition of neuro signals*

Zhang, Xiao-wen, Yang, Yu-pu, Xu, Xiao-ming, Hu, Tian-pei, Gao, Zhong-hua, Zhang, Jian, ...

Neuro signal has many more advantages than myoelectricity in providing information for prosthesis control, and can be an ideal source for developing new prosthesis. In this work, by implanting...

Cyclical Regulation of the Exocyst and Cell Polarity Determinants for Polarized Cell Growth

Zajac, Allison, Sun, Xiaoli, Zhang, Jian, Guo, Wei

Polarized exocytosis is important for morphogenesis and cell growth. The exocyst is a multiprotein complex implicated in tethering secretory vesicles at specific sites of the plasma membrane for...

Physiological properties of rod photoreceptor electrical coupling in the tiger salamander retina

Zhang, Jian, Wu, Samuel M

Using dual whole-cell voltage and current clamp recording techniques, we investigated the gap junctional conductance and the coupling coefficient between neighbouring rods in live salamander retinal...

AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice

Nottoli, Timothy, Hagopian-Donaldson, Stephanie, Zhang, Jian, Perkins, Archibald, Williams, Trevor

The homozygous disruption of the mouse AP-2 gene yields a complex and lethal phenotype that results from defective development of the neural tube, head, and body wall. The severe and pleiotropic...

The Protein Information Resource: an integrated public resource of functional annotation of proteins

Wu, Cathy H., Huang, Hongzhan, Arminski, Leslie, Castro-Alvear, Jorge, Chen, Yongxing, Hu, Zhang-Zhi, ...

The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discovery. The PIR, in...

Identification of the enzymatic mechanism of nitroglycerin bioactivation

Chen, Zhiqiang, Zhang, Jian, Stamler, Jonathan S.

Nitroglycerin (glyceryl trinitrate, GTN), originally manufactured by Alfred Nobel, has been used to treat angina and heart failure for over 130 years. However, the molecular mechanism of GTN...

Collagen-induced arthritis is exacerbated in IL-10-deficient mice

Finnegan, Alison, Kaplan, Charles D, Cao, Yanxia, Eibel, Hermann, Glant, Tibor T, Zhang, Jian

IL-10 is a potent immunoregulatory cytokine attenuating a wide range of immune effector and inflammatory responses. In the present study, we assess whether endogenous levels of IL-10 function to...

CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis

Bardos, Tamas, Czipri, Matyas, Vermes, Csaba, Finnegan, Alison, Mikecz, Katalin, Zhang, Jian

Accumulating evidence suggests that regulatory T cells play a crucial role in preventing autoimmunity. Recently, a naturally occurring CD4+CD25+ T-cell subset that is anergic and also suppressive has...

The Protein Information Resource

Wu, Cathy H., Yeh, Lai-Su L., Huang, Hongzhan, Arminski, Leslie, Castro-Alvear, Jorge, Chen, Yongxing, ...

The Protein Information Resource (PIR) is an integrated public resource of protein informatics that supports genomic and proteomic research and scientific discovery. PIR maintains the Protein...

Osteoprotegerin inhibits prostate cancer–induced osteoclastogenesis and prevents prostate tumor growth in the bone

Zhang, Jian, Dai, Jinlu, Qi, Yinghua, Lin, Din-Lii, Smith, Peter, Strayhorn, Chris, ...

Prostate cancer (CaP) forms osteoblastic skeletal metastases with an underlying osteoclastic component. However, the importance of osteoclastogenesis in the development of CaP skeletal lesions is...

Divergence of Hoxc8 early enhancer parallels diverged axial morphologies between mammals and fishes

Anand, Sanjay, Wang, Wayne C. H., Powell, Dennis R., Bolanowski, Stacey A., Zhang, Jian, Ledje, Christina, ...

There is considerable interest in understanding how cis-regulatory modifications drive morphological changes across species. Because developmental regulatory genes, including Hox genes, are...

PIRSF: family classification system at the Protein Information Resource

Wu, Cathy H., Nikolskaya, Anastasia, Huang, Hongzhan, Yeh, Lai-Su L., Natale, Darren A., Vinayaka, C. R., ...

The Protein Information Resource (PIR) is an integrated public resource of protein informatics. To facilitate the sensible propagation and standardization of protein annotation and the systematic...

Chronic alcohol ingestion induces osteoclastogenesis and bone loss through IL-6 in mice

Dai, Jinlu, Lin, Dinlii, Zhang, Jian, Habib, Paula, Smith, Peter, Murtha, Jill, ...

To investigate the role of IL-6 in alcohol-mediated osteoporosis, we measured a variety of bone remodeling parameters in wild-type (il6+/+) or IL-6 gene knockout (il6–/–) mice that were fed...

Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells

Srivastava, Meera, Eidelman, Ofer, Zhang, Jian, Paweletz, Cloud, Caohuy, Hung, Yang, QingFeng, ...

Cystic fibrosis (CF) is a fatal, autosomal, recessive genetic disease that is characterized by profound lung inflammation. The inflammatory process is believed to be caused by massive overproduction...

RACK1 Regulates G1/S Progression by Suppressing Src Kinase Activity

Mamidipudi, Vidya, Zhang, Jian, Lee, Kelly C., Cartwright, Christine A.

Cancer genes exert their greatest influence on the cell cycle by targeting regulators of a critical checkpoint in late G1. Once cells pass this checkpoint, they are fated to replicate DNA and divide....

RecA-dependent mutants in Escherichia coli reveal strategies to avoid chromosomal fragmentation

Kouzminova, Elena A., Rotman, Ella, Macomber, Lee, Zhang, Jian, Kuzminov, Andrei

RecA- and RecBC-catalyzed repair in eubacteria assembles chromosomes fragmented by double-strand breaks. We propose that recA mutants, being unable to repair fragmented chromosomes, depend on various...

Growth Rate and Cell Size Modulate the Synthesis of, and Requirement for, G1-Phase Cyclins at Start

Schneider, Brandt L., Zhang, Jian, Markwardt, J., Tokiwa, George, Volpe, Tom, Honey, Sangeet, ...

In Saccharomyces cerevisiae, commitment to cell cycle progression occurs at Start. Progression past Start requires cell growth and protein synthesis, a minimum cell size, and G1-phase cyclins. We...

Cyclical Regulation of the Exocyst and Cell Polarity Determinants for Polarized Cell Growth

Zajac, Allison, Sun, Xiaoli, Zhang, Jian, Guo, Wei

Polarized exocytosis is important for morphogenesis and cell growth. The exocyst is a multiprotein complex implicated in tethering secretory vesicles at specific sites of the plasma membrane for...

Search for Haplotype Interactions That Influence Susceptibility to Type 1 Diabetes, through Use of Unphased Genotype Data

Zhang, Jian, Liang, Faming, Dassen, Willem R. M., Doevendans, Pieter A., De Gunst, Mathisca

Type 1 diabetes is a T-cell–mediated chronic disease characterized by the autoimmune destruction of pancreatic insulin-producing β cells and complete insulin deficiency. It is the result of a...

An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation

Chen, Zhiqiang, Foster, Matthew W., Zhang, Jian, Mao, Lan, Rockman, Howard A., Kawamoto, Toshihiro, ...

The identity of the cellular mechanisms through which nitroglycerin (glyceryl trinitrate, GTN) elicits nitric oxide (NO)-based signaling to dilate blood vessels remains one of the longest standing...

Regulation of RelB Expression during the Initiation of Dendritic Cell Differentiation

Cejas, Pedro J., Carlson, Louise M., Kolonias, Despina, Zhang, Jian, Lindner, Inna, Billadeau, Daniel D., ...

The transcription factor RelB is required for proper development and function of dendritic cells (DCs), and its expression is upregulated early during differentiation from a variety of progenitors....

A mouse model of elevated intraocular pressure: retina and optic nerve findings.

Gross, Ronald L, Ji, Jianzhong, Chang, Peter, Pennesi, Mark E, Yang, Zhuo, Zhang, Jian, ...

PURPOSE: To develop and characterize a mouse model of elevated intraocular pressure (IOP) as a means to investigate the underlying cellular and genetic mechanisms of glaucomatous optic neuropathy....

Clinical detection and movement recognition of neuro signals*

Zhang, Xiao-wen, Yang, Yu-pu, Xu, Xiao-ming, Hu, Tian-pei, Gao, Zhong-hua, Zhang, Jian, ...

Neuro signal has many more advantages than myoelectricity in providing information for prosthesis control, and can be an ideal source for developing new prosthesis. In this work, by implanting...

Physiological properties of rod photoreceptor electrical coupling in the tiger salamander retina

Zhang, Jian, Wu, Samuel M

Using dual whole-cell voltage and current clamp recording techniques, we investigated the gap junctional conductance and the coupling coefficient between neighbouring rods in live salamander retinal...

Effects of Disulfide Bonds on Folding Behavior and Mechanism of the β-Sheet Protein Tendamistat

Qin, Meng, Zhang, Jian, Wang, Wei

Tendamistat, a small disulfide-bonded β-sheet protein, and its three single/double-disulfide mutants are investigated by using a modified Gō-like model, aiming to understand the folding mechanism...

Loss function approaches to predict a spatial quantile and its exceedance region

Zhang, Jian

An important problem in spatial statistics is to predict a spatial quantile and its associated exceedance region. This has applications in environmental sciences, natural resources, and agriculture,...

Application of response surface methodology in medium optimization for pyruvic acid production of Torulopsis glabrata TP19 in batch fermentation

Zhang, Jian, Gao, Nian-fa

Response surface methodology (RSM) was used to optimize the fermentation medium for enhancing pyruvic acid production by Torulopsis glabrata TP19. In the first step of optimization, with...

Conformational transition pathway in the allosteric process of human glucokinase

Zhang, Jian, Li, Chenjing, Chen, Kaixian, Zhu, Weiliang, Shen, Xu, Jiang, Hualiang

Glucokinase (GK) is an important enzyme for regulating blood glucose levels and a potentially attractive target for diabetes of the young type 2 and persistent hyperinsulinemic hypoglycemia of...

Adeno-Associated Virus-2 (AAV-2) Causes Trophoblast Dysfunction, and Placental AAV-2 Infection Is Associated with Preeclampsia

Arechavaleta-Velasco, Fabian, Ma, Yujie, Zhang, Jian, McGrath, Cindy M., Parry, Samuel

Shallow invasion by extravillous trophoblast cells into the uterine wall reduces placental perfusion and causes placental dysfunction, but the one or more causes of shallow placental invasion are...

Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool

Zhang, Jian, Frerman, Frank E., Kim, Jung-Ja P.

Electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) is a 4Fe4S flavoprotein located in the inner mitochondrial membrane. It catalyzes ubiquinone (UQ) reduction by ETF, linking oxidation...

PGE2 glycerol ester, a COX-2 oxidative metabolite of 2-arachidonoyl glycerol, modulates inhibitory synaptic transmission in mouse hippocampal neurons

Sang, Nan, Zhang, Jian, Chen, Chu

The oxygenation of endogenous cannabinoids (eCBs) 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide by cyclooxygenase-2 (COX-2) produces novel types of prostanoids: prostaglandin glycerol...

Human Prolactin Promotes Human Secondary Immunoglobulin Response in Human/SCID Mouse Chimeras▿

Zhang, Jian, Sun, Rui, Tian, Zhigang

Recombinant human prolactin (rhPRL) was administered to huPBL-SCID mice to determine its effects on production of human immunoglobulin (Ig). The huPBL-SCID mice were injected intraperitoneally (i.p.)...

THE IMPACT OF TRADE LIBERALISATION ON WATER USE: A COMPUTABLE GENERAL EQUILIBRIUM ANALYSIS

Maria Berrittella, Katrin Rehdanz, Jian Zhang

We used that GTAP-W model – GTAP5 with water resources added – to estimate the impact of hypothetical Doha-like liberalization of agricultural trade on water use. Three conclusions emerge. First,...

Predicting protein–protein interactions based only on sequences information

Shen, Juwen, Zhang, Jian, Luo, Xiaomin, Zhu, Weiliang, Yu, Kunqian, Chen, Kaixian, ...

Protein–protein interactions (PPIs) are central to most biological processes. Although efforts have been devoted to the development of methodology for predicting PPIs and protein interaction...

The establishment of two paclitaxel-resistant prostate cancer cell lines and the mechanisms of paclitaxel resistance with two cell lines

Takeda, Masashi, Mizokami, Atsushi, Mamiya, Kiminori, Li, You Qiang, Zhang, Jian, Keller, Evan T., ...

BACKGROUND Although paclitaxel is used for hormone-resistant prostate cancer, relapse definitely occurs later. Details of the molecular mechanism responsible for paclitaxel- resistance remain...

CCR2 expression correlates with prostate cancer progression

Lu, Yi, Cai, Zhong, Xiao, Guozhi, Liu, Yulin, Keller, Evan T., Yao, Zhi, ...

Although the primary role of chemokines and their receptors is controlling the trafficking of leukocytes during inflammatory responses, they also play pleoitropic roles in cancer development. There...

PTHrP-induced MCP-1 production by human bone marrow endothelial cells and osteoblasts promotes osteoclast differentiation and prostate cancer cell proliferation and invasion in vitro

Lu, Yi, Xiao, Guozhi, Galson, Deborah L., Nishio, Yoshihiko, Mizokami, Atsushi, Keller, Evan T., ...

Prostate cancer (PCa) preferentially metastasizes to bone resulting in osteoblastic lesions with underlying osteolytic activities. The mechanisms through which PCa cells promote osteolytic activities...

Characterization of Sleep in Zebrafish and Insomnia in Hypocretin Receptor Mutants

Yokogawa, Tohei, Marin, Wilfredo, Faraco, Juliette, Pézeron, Guillaume, Appelbaum, Lior, Zhang, Jian, ...

Sleep is a fundamental biological process conserved across the animal kingdom. The study of how sleep regulatory networks are conserved is needed to better understand sleep across evolution. We...

NKG2D recognition mediates Toll-like receptor 3 signaling-induced breakdown of epithelial homeostasis in the small intestines of mice

Zhou, Rongbin, Wei, Haiming, Sun, Rui, Zhang, Jian, Tian, Zhigang

Toll-like receptors (TLRs) and NK receptors are the two most important receptor families in innate immunity. Although it has been observed that TLR signaling can induce or up-regulate the expression...

Exo70p mediates the secretion of specific exocytic vesicles at early stages of the cell cycle for polarized cell growth

He, Bing, Xi, Fengong, Zhang, Jian, TerBush, Daniel, Zhang, Xiaoyu, Guo, Wei

In budding yeast, two classes of post-Golgi secretory vesicles carrying different sets of cargoes typified by Bgl2p and invertase are delivered to the plasma membrane for secretion. The exocyst is...

RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes

Armstrong, Allison P., Miller, Robert E., Jones, Jon C., Zhang, Jian, Keller, Evan T., Dougall, William C.

BACKGROUND Metastases to bone are a frequent complication of human prostate cancer and result in the development of osteoblastic lesions that include an underlying osteoclastic component. Previous...

Recent advances in asthma genetics

Zhang, Jian, Paré, Peter D, Sandford, Andrew J

There are over 100 genes that have been reported to be associated with asthma or related phenotypes. In 2006–2007 alone there were 53 novel candidate gene associations reported in the literature....

Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis

Zhang, Xiaoyu, Wang, Puyue, Gangar, Akanksha, Zhang, Jian, Brennwald, Patrick, TerBush, Daniel, ...

The tumor suppressor lethal giant larvae (Lgl) plays a critical role in epithelial cell polarization. However, the molecular mechanism by which Lgl carries out its functions is unclear. In this...

Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: Reverse docking, enzymatic assay, and X-ray crystallography validation

Cai, Jianhua, Han, Cong, Hu, Tiancen, Zhang, Jian, Wu, Dalei, Wang, Fangdao, ...

Colonization of human stomach by the bacterium Helicobacter pylori is a major causative factor for gastrointestinal illnesses and gastric cancer. However, the discovery of anti-H. pylori agents is a...

ZEOLITE THIN FILM-FIBER INTEGRATED OPTICAL SENSORS FOR HIGHLY SENSITIVE DETECTION OF CHEMICALS IN GAS AND LIQUID PHASES

ZHANG, JIAN

Abstract Quantitative measurement of trace amount of chemicals in gas and liquid phases often requires time-consuming laboratory sample preparation and sophisticated instruments that are inconvenient...

Regulation of FAS Ligand Expression during Activation-Induced Cell Death in T Cells by p38 Mitogen-Activated Protein Kinase and C-Jun Nh2-Terminal Kinase

Zhang, Jian, Gao, Jian-Xin, Salojin, Kostantin, Shao, Qing, Grattan, Marsha, Meagher, Craig, ...

Activation-induced cell death (AICD) is a mechanism of peripheral T cell tolerance that depends upon an interaction between Fas and Fas ligand (FasL). Although c-Jun NH2-terminal kinase (JNK) and p38...

Impaired Plasma Membrane Targeting of Grb2–Murine Son of Sevenless (mSOS) Complex and Differential Activation of the Fyn–T Cell Receptor (TCR)-ζ–Cbl Pathway Mediate T Cell Hyporesponsiveness in Autoimmune Nonobese Diabetic Mice

Salojin, Konstantin, Zhang, Jian, Cameron, Mark, Gill, Bruce, Arreaza, Guillermo, Ochi, Atsuo, ...

Nonobese diabetic (NOD) mouse thymocytes are hyporesponsive to T cell antigen receptor (TCR)-mediated stimulation of proliferation, and this T cell hyporesponsiveness may be causal to the onset of...

S-nitrosohemoglobin deficiency: A mechanism for loss of physiological activity in banked blood

Reynolds, James D., Ahearn, Gregory S., Angelo, Michael, Zhang, Jian, Cobb, Fred, Stamler, Jonathan S.

RBCs distribute oxygen to tissues, but, paradoxically, blood transfusion does not always improve oxygen delivery and is associated with ischemic events. We hypothesized that storage of blood would...

Two Metabotropic γ-Aminobutyric Acid Receptors Differentially Modulate Calcium Currents in Retinal Ganglion Cells

Zhang, Jian, Shen, Wen, Slaughter, Malcolm M.

Metabotropic γ-aminobutyric acid (GABA) receptors were studied in amphibian retinal ganglion cells using whole cell current and voltage clamp techniques. The aim was to identify the types of...

Identification and Analysis of a Conserved Tcfap2a Intronic Enhancer Element Required for Expression in Facial and Limb Bud Mesenchyme▿ †

Feng, Weiguo, Huang, Jian, Zhang, Jian, Williams, Trevor

Tcfap2a, the gene encoding the mouse AP-2α transcription factor, is required for normal development of multiple structures during embryogenesis, including the face and limbs. Using comparative...

Can Renminbi Appreciation Reduce the US Trade Deficit?

Jian Zhang, Hung-Gay Fung, Donald Kummer

Using a computational general equilibrium model, we analyze the impacts of Chinese real exchange rate appreciation on the trade balance of China and the USA and on various industries of both...

An Assessment of the Closer Economic Partnership Arrangement Between China and Hong Kong

Hung-Gay Fung, Jian Zhang

In 2004, China and Hong Kong established a free trade agreement (FTA) called the Closer Economic Partnership Arrangement, intended to phase out all trade barriers to trade and investment between...

Self-Employment with Chinese Characteristics: The Forgotten Engine of Rural China's Growth

Jian Zhang, Linxiu Zhang, Scott Rozelle, Steve Boucher

This article sketches a picture of the self-employment sector in rural China and examines the nature of its emergence. Using a randomly selected, nationally representative household-level data set...

Functional Characterization of the Arabidopsis Eukaryotic Translation Initiation Factor 5A-2 That Plays a Crucial Role in Plant Growth and Development by Regulating Cell Division, Cell Growth, and Cell Death1[OA]

Feng, Haizhong, Chen, Qingguo, Feng, Jian, Zhang, Jian, Yang, Xiaohui, Zuo, Jianru

The eukaryotic translation initiation factor 5A (eIF-5A) is a highly conserved protein found in all eukaryotic organisms. Although originally identified as a translation initiation factor, recent...

Membrane association and functional regulation of Sec3 by phospholipids and Cdc42

Zhang, Xiaoyu, Orlando, Kelly, He, Bing, Xi, Fengong, Zhang, Jian, Zajac, Allison, ...

The exocyst is an octameric protein complex implicated in tethering post-Golgi secretory vesicles at the plasma membrane in preparation for fusion. However, it is not clear how the exocyst is...

T-Cell Receptor-Induced NF-κB Activation Is Negatively Regulated by E3 Ubiquitin Ligase Cbl-b▿

Qiao, Guilin, Li, Zhenping, Molinero, Luciana, Alegre, Maria-Luisa, Ying, Haiyan, Sun, Zuoming, ...

It has previously been shown that E3 ubiquitin ligase Casitas B-lineage lymphoma-b (Cbl-b) negatively regulates T-cell activation, but the molecular mechanism(s) underlying this inhibition is not...

Ccr4 Alters Cell Size in Yeast by Modulating the Timing of CLN1 and CLN2 Expression

Manukyan, Arkadi, Zhang, Jian, Thippeswamy, Uma, Yang, Jingye, Zavala, Noelle, Mudannayake, Malkanthi P., ...

Large, multisubunit Ccr4-Not complexes are evolutionarily conserved global regulators of gene expression. Deletion of CCR4 or several components of Ccr4-Not complexes results in abnormally large...

A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis

Zhang, Jian, Van Lanen, Steven G., Ju, Jianhua, Liu, Wen, Dorrestein, Pieter C., Li, Wenli, ...

The enediynes, unified by their unique molecular architecture and mode of action, represent some of the most potent anticancer drugs ever discovered. The biosynthesis of the enediyne core has been...

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Shangary, Sanjeev, Qin, Dongguang, McEachern, Donna, Liu, Meilan, Miller, Rebecca S., Qiu, Su, ...

We have designed MI-219 as a potent, highly selective and orally active small-molecule inhibitor of the MDM2–p53 interaction. MI-219 binds to human MDM2 with a Ki value of 5 nM and is 10,000-fold...

N-Myc downstream-regulated gene 2 is involved in p53-mediated apoptosis

Liu, Na, Wang, Lifeng, Li, Xia, Yang, Qi, Liu, Xinping, Zhang, Jing, ...

The tumor suppressor, p53, is a transcription factor which can modulate the transcription of a number of target genes that are involved in cell-cycle arrest and apoptosis. However, the apoptotic...

Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane

He, Bing, Xi, Fengong, Zhang, Xiaoyu, Zhang, Jian, Guo, Wei

The exocyst is an octameric protein complex implicated in the tethering of post-Golgi secretory vesicles to the plasma membrane before fusion. The function of individual exocyst components and the...

Data Sphering: Some Properties and Applications

Jian Zhang

Sphering, dispersion matrix, invariance, asymptotics, projection pursuit,

Estimating the false discovery rate using the stochastic approximation algorithm

Jian Zhang

Testing of multiple hypotheses involves statistics that are strongly dependent in some applications, but most work on this subject is based on the assumption of independence. We propose a new method...

Some Extensions of Tukey's Depth Function

Zhang, Jian

As the extensions of Tukey's depth, a family of affine invariant depth functions are introduced for multivariate location and dispersion. The location depth functions can be used for the purpose of...

Learning Bayesian networks for discrete data

Liang, Faming, Zhang, Jian

Bayesian networks have received much attention in the recent literature. In this article, we propose an approach to learn Bayesian networks using the stochastic approximation Monte Carlo (SAMC)...

Monocyte Chemotactic Protein 1 Promotes Lung Cancer-Induced Bone Resorptive Lesions In Vivo1

Cai, Zhong, Chen, Qiuyan, Chen, Jun, Lu, Yi, Xiao, Guozhi, Wu, Zhihao, ...

Lung cancer is the leading cause of cancer-related deaths. The morbidity and mortality of lung cancer have markedly increased in the past decade with at least 75% of patients with lung cancer having...

Serine Palmitoyltransferase, a Key Enzyme for de Novo Synthesis of Sphingolipids, Is Essential for Male Gametophyte Development in Arabidopsis1[W][OA]

Teng, Chong, Dong, Haili, Shi, Lihua, Deng, Yan, Mu, Jinye, Zhang, Jian, ...

Sphingolipids are important signaling molecules involved in various cellular activities. De novo sphingolipid synthesis is initiated by a rate-limiting enzyme, serine palmitoyltransferase (SPT), a...

Parathyroid Hormone Increases Activating Transcription Factor 4 Expression and Activity in Osteoblasts: Requirement for Osteocalcin Gene Expression

Yu, Shibing, Franceschi, Renny T., Luo, Min, Zhang, Xiaoyan, Jiang, Di, Lai, Yumei, ...

PTH is an important peptide hormone regulator of calcium homeostasis and osteoblast function. However, its mechanism of action in osteoblasts is poorly understood. Our previous study demonstrated...

Focal and segmental glomerulosclerosis induced in mice lacking decay-accelerating factor in T cells

Bao, Lihua, Haas, Mark, Pippin, Jeffrey, Wang, Ying, Miwa, Takashi, Chang, Anthony, ...

Heritable and acquired diseases of podocytes can result in focal and segmental glomerulosclerosis (FSGS). We modeled FSGS by passively transferring mouse podocyte–specific sheep Abs into BALB/c...

Regiospecific O-Methylation of Naphthoic Acids Catalyzed by NcsB1, an O-Methyltransferase Involved in the Biosynthesis of the Enediyne Antitumor Antibiotic Neocarzinostatin*S⃞

Luo, Yinggang, Lin, Shuangjun, Zhang, Jian, Cooke, Heather A., Bruner, Steven D., Shen, Ben

Neocarzinostatin, a clinical anticancer drug, is the archetypal member of the chromoprotein family of enediyne antitumor antibiotics that are composed of a nonprotein chromophore and an apoprotein....

Regulation of Gic2 Localization and Function by Phosphatidylinositol 4,5-Bisphosphate during the Establishment of Cell Polarity in Budding Yeast*S⃞

Orlando, Kelly, Zhang, Jian, Zhang, Xiaoyu, Yue, Peng, Chiang, Teresa, Bi, Erfei, ...

Establishment of cell polarity is important for a wide range of biological processes, from asymmetric cell growth in budding yeast to neurite formation in neurons. In the yeast Saccharomyces...

SELF-EMPLOYMENT WITH CHINESE CHARACTERISTICS: THE FORGOTTEN ENGINE OF RURAL CHINA'S GROWTH

JIAN ZHANG, LINXIU ZHANG, SCOTT ROZELLE, STEVE BOUCHER

This article sketches a picture of the self-employment sector in rural China and examines the nature of its emergence. Using a randomly selected, nationally representative household-level data set...

LEAFY COTYLEDON1 Is a Key Regulator of Fatty Acid Biosynthesis in Arabidopsis1[C][W][OA]

Mu, Jinye, Tan, Helin, Zheng, Qi, Fu, Fuyou, Liang, Yan, Zhang, Jian, ...

In plants, fatty acids are de novo synthesized predominantly in plastids from acetyl-coenzyme A. Although fatty acid biosynthesis has been biochemically well studied, little is known about the...

An Examination of the Association Between Gender and Reporting Intentions for Fraudulent Financial Reporting

Steven Kaplan, Kurt Pany, Janet Samuels, Jian Zhang

whistleblowing, gender, fraudulentreporting, anonymous reporting channel, non-anonymous reporting channel,

Protein-coding gene promoters in Methanocaldococcus (Methanococcus) jannaschii

Zhang, Jian, Li, Enhu, Olsen, Gary J.

Although Methanocaldococcus (Methanococcus) jannaschii was the first archaeon to have its genome sequenced, little is known about the promoters of its protein-coding genes. To expand our knowledge,...

PubChem: a public information system for analyzing bioactivities of small molecules

Wang, Yanli, Xiao, Jewen, Suzek, Tugba O., Zhang, Jian, Wang, Jiyao, Bryant, Stephen H.

PubChem (http://pubchem.ncbi.nlm.nih.gov) is a public repository for biological properties of small molecules hosted by the US National Institutes of Health (NIH). PubChem BioAssay database currently...

Lys169 of Human Glucokinase Is a Determinant for Glucose Phosphorylation: Implication for the Atomic Mechanism of Glucokinase Catalysis

Zhang, Jian, Li, Chenjing, Shi, Ting, Chen, Kaixian, Shen, Xu, Jiang, Hualiang

Glucokinase (GK), a glucose sensor, maintains plasma glucose homeostasis via phosphorylation of glucose and is a potential therapeutic target for treating maturity-onset diabetes of the young (MODY)...

The Effects of Climate Change on Agriculture

Francesco Bosello, Jian Zhang

The economy implications that climate change holds for agricultural sectors in 2050 are estimated using a static computable general equilibrium model. A peculiar feature of this exercise is the...

Androgen Deprivation by Activating the Liver X Receptor

Hoon Lee, Jung, Gong, Haibiao, Khadem, Shaheen, Lu, Yi, Gao, Xiang, Li, Song, ...

Prostate cancer is the most commonly diagnosed and the second leading cause of cancer death in men. The androgens-androgen receptor signaling plays an important role in normal prostate development,...

The Two-Domain LysX Protein of Mycobacterium tuberculosis Is Required for Production of Lysinylated Phosphatidylglycerol and Resistance to Cationic Antimicrobial Peptides

Maloney, Erin, Stankowska, Dorota, Zhang, Jian, Fol, Marek, Cheng, Qi-Jian, Lun, Shichun, ...

The well-recognized phospholipids (PLs) of Mycobacterium tuberculosis (Mtb) include several acidic species such as phosphatidylglycerol (PG), cardiolipin, phosphatidylinositol and its mannoside...

An analysis of the relationship between accounting restatements and quantitative benchmarks of audit planning materiality

Hanmei Chen, Kurt Pany, Jian Zhang

Purpose – The purpose of this paper is to investigate the relationship between the amounts obtained using professionally accepted quantitative benchmarks of audit planning materiality and the size...

Regulation of local governments and enterprise formation in rural China

Jian Zhang, Sandeep Mohapatra, Steve Boucher, Scott Rozelle

With the rise of the private sector in rural China, power has been shifting from the hands of local government officials to the hands of entrepreneurs. In this situation, economic theory offers two...

Endocannabinoid 2-Arachidonoylglycerol Protects Neurons by Limiting COX-2 Elevation*S⃞

Zhang, Jian, Chen, Chu

Endocannabinoids are involved in synaptic signaling and neuronal protection; however, our understanding of the mechanisms by which endocannabinoids protect neurons from harmful insults remains...

Chronic mesenteric artery insufficiency produces hyperplasia of the intestine – case report

Wang, ZhongGao, Yu, HenXi, Gu, YongQuan, Li, JianXin, Zhang, Jian, Li, Zhen

Chronic ischemia produces corresponding tissue hypoplasia. However, the present paper reports a distinctive hypertrophy of the intestine due to chronic mesenteric artery insufficiency. Two patients...

India’s Optimal Trade Strategy: A General Equilibrium Analysis

Zhang, Jian, Fung, Hung-Gay, Sawhney, Bansi

Using a conventional multi-region, multi-sectoral global trade analysis project (GTAP) model, we analyze the effects of India’s trade liberalization policies on its output, trade, and welfare. We...

Transcriptional Regulation of PP2A-Aα Is Mediated by Multiple Factors Including AP-2α, CREB, ETS-1, and SP-1

Chen, He-Ge, Han, Wen-Jun, Deng, Mi, Qin, Jichao, Yuan, Dan, Liu, Jin-Ping, ...

Protein phosphatases-2A (PP-2A) is a major serine/threonine phosphatase and accounts for more than 50% serine/threonine phosphatase activity in eukaryotes. The holoenzyme of PP-2A consists of the...

Systems Integration of Biodefense Omics Data for Analysis of Pathogen-Host Interactions and Identification of Potential Targets

McGarvey, Peter B., Huang, Hongzhan, Mazumder, Raja, Zhang, Jian, Chen, Yongxing, Zhang, Chengdong, ...

The NIAID (National Institute for Allergy and Infectious Diseases) Biodefense Proteomics program aims to identify targets for potential vaccines, therapeutics, and diagnostics for agents of concern...

Messenger RNA processing in Methanocaldococcus (Methanococcus) jannaschii

Zhang, Jian, Olsen, Gary J.

Messenger RNA (mRNA) processing plays important roles in gene expression in all domains of life. A number of cases of mRNA cleavage have been documented in Archaea, but available data are...

Critical Role of Activating Transcription Factor 4 in the Anabolic Actions of Parathyroid Hormone in Bone

Yu, Shibing, Franceschi, Renny T., Luo, Min, Fan, Jie, Jiang, Di, Cao, Huiling, ...

Parathyroid hormone (PTH) is a potent anabolic agent for the treatment of osteoporosis. However, its mechanism of action in osteoblast and bone is not well understood. In this study, we show that the...

First Insight into Genetic Diversity of the Mycobacterium tuberculosis Complex in Albania Obtained by Multilocus Variable-Number Tandem-Repeat Analysis and Spoligotyping Reveals the Presence of Beijing Multidrug-Resistant Isolates ▿

Tafaj, Silva, Zhang, Jian, Hauck, Yolande, Pourcel, Christine, Hafizi, Hasan, Zoraqi, Grigor, ...

We characterized a set of 100 Mycobacterium tuberculosis complex clinical isolates from tuberculosis (TB) patients in Albania, typing them with a 24-locus variable-number tandem-repeat-spoligotyping...

Mbd3, a Component of NuRD/Mi-2 Complex, Helps Maintain Pluripotency of Mouse Embryonic Stem Cells by Repressing Trophectoderm Differentiation

Zhu, Dongmei, Fang, Junshun, Li, Yanxin, Zhang, Jian

Embryonic stem cells (ES cells) can differentiate into cells derived from all three germ layers and extraembryonic tissues. While transcription factors such as, Oct4 and Nanog are well known for...