Jiang Qian, Marisa Dolled-filhart, Jimmy Lin, Haiyuan Yu, Mark Gerstein
The complexity of biological systems provides for a great diversity of relationships between genes. The current analysis of whole-genome expression data focuses on relationships based on global...
Relating periodicity of nucleosome organization and gene regulation (2009)
Wan, Jun, Lin, Jimmy, Zack, Donald J., Qian, Jiang
Motivation: The relationship between nucleosome positioning and gene regulation is fundamental yet complex. Previous studies on genomic nucleosome positions have revealed a correlation between...
Dov Greenbaum, Nicholas M. Luscombe, Ronald Jansen, Jiang Qian, Mark Gerstein
With the completion of genome sequences, the current challenge for biology is to determine the functions of all gene products and to understand how they contribute in making an organism viable. For...
Imaging and manipulating electrons in a 1D quantum dot with Coulomb blockade microscopy (2008)
Qian, Jiang, Halperin, Bertrand I., Heller, Eric J.
Motivated by the recent experiments by the Westervelt group using a mobile tip to probe the electronic state of quantum dots formed on a segmented nanowire, we study the shifts in Coulomb blockade...
TiGER: A database for tissue-specific gene expression and regulation (2008)
Liu, Xiong, Yu, Xueping, Zack, Donald J, Zhu, Heng, Qian, Jiang
Abstract Background Understanding how genes are expressed and regulated in different tissues is a fundamental and challenging question. However, most of currently available biological databases do...
In Proc. of Communications and Multimedia Security, 2001. (2008)
Jiang Qian, Susan Hinrichs, Klara Nahrstedt, Jiang Qian, Susan Hinrichs, Klara Nahrstedt
vulnerability test, policy based management, global policy, access control list, ACL optimisation, ACL analysis, packet classification, firewall, packet filtering Abstract: It is a challenging task...
Analysis of regulatory network topology reveals functionally distinct classes of microRNAs (2008)
Yu, Xueping, Lin, Jimmy, Zack, Donald J., Mendell, Joshua T., Qian, Jiang
MicroRNAs (miRNAs) negatively regulate the expression of target genes at the post-transcriptional level. Little is known about the crosstalk between miRNAs and transcription factors (TFs). Here we...
We present an analytical study of the time dependent diffusion coefficient in a dilute suspension of spheres with partially absorbing boundary condition. Following Kirkpatrick (J. Chem. Phys. 76,...
Yu, Xueping, Lin, Jimmy, Zack, Donald J, Qian, Jiang
Abstract Background Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivated by...
Cai, Yu-Dong, Jen, Chi-Hung, Qian, Jiang, Qian, ZiLiang, Muldoon, Mark
Defining regulatory networks, linking transcription factors (TFs) to their targets, is a central problem in post-genomic biology. Here we apply an approach based on Nearest Neighbour (NN) Algorithm...
Hartree-Fock calculations of a finite inhomogeneous quantum wire (2007)
Qian, Jiang, Halperin, Bertrand I.
We use the Hartree-Fock method to study an interacting one-dimensional electron system on a finite wire, partially depleted at the center by a smooth potential barrier. A uniform one-Tesla Zeeman...
Yu, Haiyuan, Nguyen, Katherine, Royce, Tom, Qian, Jiang, Nelson, Kenneth, Snyder, Michael, ...
Microarray technology is currently one of the most widely-used technologies in biology. Many studies focus on inferring the function of an unknown gene from its co-expressed genes. Here, we are able...
Characterization of transcription-independent APC tumor suppressor function in apoptosis (2006)
The APC tumor suppressor is a multifunctional protein involved in cell migration, proliferation, differentiation and apoptosis. It is a component of the Wnt signaling pathway and is best known for...
Antemortem Diagnosis of New York Human Rabies Case and Review of U. S. Cases (2006)
Vince V. Soun, Millicent Eidson, Charles V. Trimarchi, Peter D. Drabkin, Richard Leach, Barbara J. Wallace, ...
A human case of imported dog-variant rabies is described and compared with previous cases to elucidate clinical patterns and methods to improve early confirmation and triage of human contacts to...
Abstract. The recurrence algorithm is given for the calculation of NUAH B-splines in the space Sn+1 = span{sinh t, cosh t, t n−3, · · · , t 2, t,1} (n ≥ 3). The case of NUAH B-spline bases of...
Yu, Xueping, Lin, Jimmy, Zack, Donald J., Qian, Jiang
Tissue-specific gene expression is generally regulated by more than a single transcription factor (TF). Multiple TFs work in concert to achieve tissue specificity. In order to explore these complex...
Yu, Xueping, Lin, Jimmy, Masuda, Tomohiro, Esumi, Noriko, Zack, Donald J., Qian, Jiang
Combinatorial regulation by transcription factor complexes is an important feature of eukaryotic gene regulation. Here, we propose a new method for identification of interactions between...
Yu, Xueping, Lin, Jimmy, Zack, Donald J., Qian, Jiang
Tissue-specific gene expression is generally regulated by more than a single transcription factor (TF). Multiple TFs work in concert to achieve tissue specificity. In order to explore these complex...
Yu, Haiyuan, Nguyen, Katherine, Royce, Tom, Qian, Jiang, Nelson, Kenneth, Snyder, Michael, ...
Microarray technology is currently one of the most widely-used technologies in biology. Many studies focus on inferring the function of an unknown gene from its co-expressed genes. Here, we are able...
Yu, Xueping, Lin, Jimmy, Zack, Donald J., Qian, Jiang
Tissue-specific gene expression is generally regulated by more than a single transcription factor (TF). Multiple TFs work in concert to achieve tissue specificity. In order to explore these complex...
Yu, Haiyuan, Nguyen, Katherine, Royce, Tom, Qian, Jiang, Nelson, Kenneth, Snyder, Michael, ...
Microarray technology is currently one of the most widely-used technologies in biology. Many studies focus on inferring the function of an unknown gene from its co-expressed genes. Here, we are able...
Hard superconducting nitrides (2005)
Chen, Xiao-Jia, Struzhkin, Viktor V., Wu, Zhigang, Somayazulu, Maddury, Qian, Jiang, Kung, Simon, ...
Detailed study of the equation of state, elasticity, and hardness of selected superconducting transition-metal nitrides reveals interesting correlations among their physical properties. Both the bulk...
Theory of momentum resolved tunneling into a short quantum wire (2005)
Fiete, Gregory A., Qian, Jiang, Tserkovnyak, Yaroslav, Halperin, Bertrand I.
Motivated by recent tunneling experiments in the parallel wire geometry, we calculate results for momentum resolved tunneling into a short one-dimensional wire, containing a small number of...
Qian, Jiang, Esumi, Noriko, Chen, Yangjian, Wang, Qingliang, Chowers, Itay, Zack, Donald J.
Identification of tissue-specific gene regulatory networks can yield insights into the molecular basis of a tissue's development, function and pathology. Here, we present a computational approach...
Genetic and expression profiles of cerebellar liponeurocytomas (2004)
Horstmann, Sonia, Perry, Arie, Reifenberger, Guido, Giangaspero, Felice, Huang, Herve, Hara, Akira, ...
Cerebellar liponeurocytoma, a rare, newly identified CNS neoplasm of adults, is characterized by advanced neuronal/neurocytic and focal lipomatous differentiation, low proliferative potential and a...
Relationship between gene co-expression and probe localization on microarray slides (2003)
Kluger, Yuval, Yu, Haiyuan, Qian, Jiang, Gerstein, Mark
Abstract Background Microarray technology allows simultaneous measurement of thousands of genes in a single experiment. This is a potentially useful tool for evaluating co-expression of genes and...
Diamond/silicon carbide composites sintered under high pressure-high temperature conditions / (2003)
Thesis (Ph. D.)--Texas Christian University, 2003.
Qian, Jiang, Lin, Jimmy, Luscombe, Nicholas M., Yu, Haiyuan, Gerstein, Mark
Motivation: Defining regulatory networks, linking transcription factors (TFs) to their targets, is a central problem in post-genomic biology. One might imagine one could readily determine these...
Luscombe, Nicholas M, Qian, Jiang, Zhang, Zhaolei, Johnson, Ted, Gerstein, Mark
Abstract Background The sequencing of genomes provides us with an inventory of the 'molecular parts' in nature, such as protein families and folds, and their functions in living organisms. Through...
Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae (2002)
Horak, Christine E., Luscombe, Nicholas M., Qian, Jiang, Bertone, Paul, Piccirrillo, Stacy, Gerstein, Mark, ...
Thesis (M.S.)--Western Kentucky University, 2000.
Mainz, University, Diss., 1999.
A Bayesian Weibull Survival Model (1994)
Jiang Qian, Jiang Qian, Donald A. Berry, Donald A. Berry, Donald S. Burdick, Donald S. Burdick, ...
(Statistics) A BAYESIAN WEIBULL SURVIVAL MODEL by Jiang Qian Institute of Statistics and Decision Sciences Duke University Date: Approved: Donald A. Berry, Advisor Donald S. Burdick Saurabh...
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Qian, Jiang, Stenger, Brad, Wilson, Cyrus A., Lin, Jimmy, Jansen, Ronald, Teichmann, Sarah A., ...
As the number of protein folds is quite limited, a mode of analysis that will be increasingly common in the future, especially with the advent of structural genomics, is to survey and re-survey the...
Cato, Allen, Qian, Jiang, Hsu, Ann, Levy, Benjamin, Leonard, John, Granneman, Richard
The effect of coadministration of ritonavir and zidovudine (ZDV) on the pharmacokinetics of these drugs was investigated in a three-period, multidose, crossover study. Eighteen asymptomatic, human...
Effect of Fluoxetine on Pharmacokinetics of Ritonavir
Ouellet, Daniele, Hsu, Ann, Qian, Jiang, Lamm, Janet E., Cavanaugh, John H., Leonard, John M., ...
The potential interaction between fluoxetine, a known inhibitor of cytochrome P-450 isoform 2D6 (CYP2D6), and ritonavir, a human immunodeficiency virus type 1 protease inhibitor, was evaluated in...
Luscombe, Nicholas M, Qian, Jiang, Zhang, Zhaolei, Johnson, Ted, Gerstein, Mark
The sequencing of genomes provides us with an inventory of the 'molecular parts' in nature, such as protein families and folds, and their functions in living organisms. The genomic occurrence of...
Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae
Horak, Christine E., Luscombe, Nicholas M., Qian, Jiang, Bertone, Paul, Piccirrillo, Stacy, Gerstein, Mark, ...
In the yeast Saccharomyces cerevisiae, SBF (Swi4–Swi6 cell cycle box binding factor) and MBF (MluI binding factor) are the major transcription factors regulating the START of the cell cycle, a time...
A quenchable superhard carbon phase synthesized by cold compression of carbon nanotubes
Wang, Zhongwu, Zhao, Yusheng, Tait, Kimberly, Liao, Xiaozhou, Schiferl, David, Zha, Changsheng, ...
A quenchable superhard high-pressure carbon phase was synthesized by cold compression of carbon nanotubes. Carbon nanotubes were placed in a diamond anvil cell, and x-ray diffraction measurements...
Chen, Xiao-Jia, Struzhkin, Viktor V., Wu, Zhigang, Somayazulu, Maddury, Qian, Jiang, Kung, Simon, ...
Detailed study of the equation of state, elasticity, and hardness of selected superconducting transition-metal nitrides reveals interesting correlations among their physical properties. Both the bulk...
Qian, Jiang, Esumi, Noriko, Chen, Yangjian, Wang, Qingliang, Chowers, Itay, Zack, Donald J.
Identification of tissue-specific gene regulatory networks can yield insights into the molecular basis of a tissue's development, function and pathology. Here, we present a computational approach...
Yu, Xueping, Lin, Jimmy, Masuda, Tomohiro, Esumi, Noriko, Zack, Donald J., Qian, Jiang
Combinatorial regulation by transcription factor complexes is an important feature of eukaryotic gene regulation. Here, we propose a new method for identification of interactions between...
Metastatic Alveolar Soft-Part Sarcoma of the Intracranial Skull Base: Case Report
Cohen, David B., Jones, David M., Fergus, Allan H., Qian, Jiang, Schwartz, Marc S.
A patient with an intracranial skull base alveolar soft-part sarcoma, thought on preoperative imaging to be a meningioma, is presented. The mass was removed and identified by pathological evaluation...
Yu, Xueping, Lin, Jimmy, Zack, Donald J., Qian, Jiang
Tissue-specific gene expression is generally regulated by more than a single transcription factor (TF). Multiple TFs work in concert to achieve tissue specificity. In order to explore these complex...
Qian, Jiang, Stenger, Brad, Wilson, Cyrus A., Lin, Jimmy, Jansen, Ronald, Teichmann, Sarah A., ...
As the number of protein folds is quite limited, a mode of analysis that will be increasingly common in the future, especially with the advent of structural genomics, is to survey and re-survey the...
Cato, Allen, Qian, Jiang, Hsu, Ann, Levy, Benjamin, Leonard, John, Granneman, Richard
The effect of coadministration of ritonavir and zidovudine (ZDV) on the pharmacokinetics of these drugs was investigated in a three-period, multidose, crossover study. Eighteen asymptomatic, human...
Effect of Fluoxetine on Pharmacokinetics of Ritonavir
Ouellet, Daniele, Hsu, Ann, Qian, Jiang, Lamm, Janet E., Cavanaugh, John H., Leonard, John M., ...
The potential interaction between fluoxetine, a known inhibitor of cytochrome P-450 isoform 2D6 (CYP2D6), and ritonavir, a human immunodeficiency virus type 1 protease inhibitor, was evaluated in...
Luscombe, Nicholas M, Qian, Jiang, Zhang, Zhaolei, Johnson, Ted, Gerstein, Mark
The sequencing of genomes provides us with an inventory of the 'molecular parts' in nature, such as protein families and folds, and their functions in living organisms. The genomic occurrence of...
Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae
Horak, Christine E., Luscombe, Nicholas M., Qian, Jiang, Bertone, Paul, Piccirrillo, Stacy, Gerstein, Mark, ...
In the yeast Saccharomyces cerevisiae, SBF (Swi4–Swi6 cell cycle box binding factor) and MBF (MluI binding factor) are the major transcription factors regulating the START of the cell cycle, a time...
A quenchable superhard carbon phase synthesized by cold compression of carbon nanotubes
Wang, Zhongwu, Zhao, Yusheng, Tait, Kimberly, Liao, Xiaozhou, Schiferl, David, Zha, Changsheng, ...
A quenchable superhard high-pressure carbon phase was synthesized by cold compression of carbon nanotubes. Carbon nanotubes were placed in a diamond anvil cell, and x-ray diffraction measurements...
Chen, Xiao-Jia, Struzhkin, Viktor V., Wu, Zhigang, Somayazulu, Maddury, Qian, Jiang, Kung, Simon, ...
Detailed study of the equation of state, elasticity, and hardness of selected superconducting transition-metal nitrides reveals interesting correlations among their physical properties. Both the bulk...
Qian, Jiang, Esumi, Noriko, Chen, Yangjian, Wang, Qingliang, Chowers, Itay, Zack, Donald J.
Identification of tissue-specific gene regulatory networks can yield insights into the molecular basis of a tissue's development, function and pathology. Here, we present a computational approach...
Yu, Xueping, Lin, Jimmy, Masuda, Tomohiro, Esumi, Noriko, Zack, Donald J., Qian, Jiang
Combinatorial regulation by transcription factor complexes is an important feature of eukaryotic gene regulation. Here, we propose a new method for identification of interactions between...
Yu, Xueping, Lin, Jimmy, Zack, Donald J., Qian, Jiang
Tissue-specific gene expression is generally regulated by more than a single transcription factor (TF). Multiple TFs work in concert to achieve tissue specificity. In order to explore these complex...
Metastatic Alveolar Soft-Part Sarcoma of the Intracranial Skull Base: Case Report
Cohen, David B., Jones, David M., Fergus, Allan H., Qian, Jiang, Schwartz, Marc S.
A patient with an intracranial skull base alveolar soft-part sarcoma, thought on preoperative imaging to be a meningioma, is presented. The mass was removed and identified by pathological evaluation...
Yu, Haiyuan, Nguyen, Katherine, Royce, Tom, Qian, Jiang, Nelson, Kenneth, Snyder, Michael, ...
Microarray technology is currently one of the most widely-used technologies in biology. Many studies focus on inferring the function of an unknown gene from its co-expressed genes. Here, we are able...
Effect of ritonavir on the pharmacokinetics of ethinyl oestradiol in healthy female volunteers
Ouellet, Daniele, Hsu, Ann, Qian, Jiang, Locke, Charles S, Eason, Carolyn J, Cavanaugh, John H, ...
Characterization of transcription-independent APC tumor suppressor function in apoptosis
The APC tumor suppressor is a multifunctional protein involved in cell migration, proliferation, differentiation and apoptosis. It is a component of the Wnt signaling pathway and is best known for...
TiGER: A database for tissue-specific gene expression and regulation
Liu, Xiong, Yu, Xueping, Zack, Donald J, Zhu, Heng, Qian, Jiang
Analysis of regulatory network topology reveals functionally distinct classes of microRNAs
Yu, Xueping, Lin, Jimmy, Zack, Donald J., Mendell, Joshua T., Qian, Jiang
MicroRNAs (miRNAs) negatively regulate the expression of target genes at the post-transcriptional level. Little is known about the crosstalk between miRNAs and transcription factors (TFs). Here we...
Lectin microarrays identify cell-specific and functionally significant cell surface glycan markers
Tao, Sheng-Ce, Li, Yu, Zhou, Jiangbing, Qian, Jiang, Schnaar, Ronald L, Zhang, Ying, ...
Glycosylation is among the most complex posttranslational modifications with an extremely high level of diversity that has made it refractory to high-throughput analyses. Despite its resistance to...
Kung, Li A, Tao, Sheng-Ce, Qian, Jiang, Smith, Michael G, Snyder, Michael, Zhu, Heng
To further understand the roles of protein glycosylation in eukaryotes, we globally identified glycan-containing proteins in yeast. A fluorescent lectin binding assay was developed and used to screen...