The Importance of Human FcγRI in Mediating Protection to Malaria (2007)
Richard S. McIntosh, Jianguo Shi, Richard M. Jennings, Jonathan C. Chappel, Tim Smith, ...
The success of passive immunization suggests that antibody-based therapies will be effective at controlling malaria. We describe the development of fully human antibodies specific for Plasmodium...
Importance of human FcyRI in mediating protection to malaria (2007)
McIntosh, Richard S., Shi, Jianguo, Jennings, Richard M., Chappel, Jonathan C., Smith, Tim, ...
The success of passive immunization suggests that antibody-based therapies will be effective at controlling malaria. We describe the development of fully human antibodies specific for Plasmodium...
The importance of human FcyRI in mediating protection to malaria (2007)
McIntosh, Richard S., Shi, Jianguo, Jennings, Richard M., Chappel, Jonathan C., Smith, Tim, ...
The success of passive immunization suggests that antibody-based therapies will be effective at controlling malaria. We describe the development of fully human antibodies specific for Plasmodium...
Young, Robert J., Owens, Raymond J., Mackay, Graham A., Chan, Christina M. W., Shi, Jianguo, Hide, Michihiro, ...
We have constructed an expression vector that leads to secretion of the whole Fc of human immunoglobulin E (hIgE-Fc) from mammalian cells at levels up to 100 mg/l of culture. Two surface...
The Importance of Human FcγRI in Mediating Protection to Malaria
McIntosh, Richard S, Shi, Jianguo, Jennings, Richard M, Chappel, Jonathan C, Smith, Tim, ...
The success of passive immunization suggests that antibody-based therapies will be effective at controlling malaria. We describe the development of fully human antibodies specific for Plasmodium...
Attenuation of IgE Affinity for FcεRI Radically Reduces the Allergic Response in Vitro and in Vivo*
Hunt, James, Bracher, Marguerite G., Shi, Jianguo, Fleury, Sébastien, Dombrowicz, David, Gould, Hannah J., ...
The high affinity of IgE for its receptor, FcεRI (Ka ∼ 1010 m–1), is responsible for the persistence of mast cell sensitization. Cross-linking of FcεRI-bound IgE by multivalent allergen leads...