Jie Liang

Publication List Details

Period

1986 - 2009

Number

150

Co-Authors

Name: (2009)

Božidar Vujičić, In The, Božidar Vujičić, Božidar Vujičić, Dr. Jie Liang, Senior Supervisor

and characterization of traffic in a public safety wireless network Examining Committee: Chair:

Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population (2009)

Jin, Guangfu, Xu, Lin, Shu, Yongqian, Tian, Tian, Liang, Jie, Xu, Yan, ...

Chromosome 5p15.33, containing TERT and CLPTM1L genes, was recently identified as one of the susceptible regions for lung cancer in Caucasian populations. We hypothesized that single-nucleotide...

Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen quality (2009)

Ji, Guixiang, Gu, Aihua, Hu, Fan, Wang, Shoulin, Liang, Jie, Xia, Yankai, ...

BACKGROUNDThe FAS/FASLG system has been proposed to play a key role in germ cell apoptosis. To elucidate the role of the genetic variants of cell death pathway genes in male infertility, we genotyped...

Developing optimal non-linear scoring function for protein design. Bioinformatics 2004;20:3080–3098 (2008)

Changyu Hu, Xiang Li, Jie Liang

Motivation. Protein design aims to identify sequences compatible with a given protein fold but incompatible to any alternative folds. To select the correct sequences and to guide the search process,...

Packing and function (2008)

Jie Liang

geometry and its applications:

Integrating Specification and Documentation in an Object-Oriented Language (2008)

Jie Liang

This paper reports on the integration of specification and documentation features into an object-oriented programming language and its compiler. The goal of this integration is to improve software...

by matching local surfaces: a Bayesian Monte Carlo (2008)

Yan Yuan Tseng, Jie Liang

Evolutionary model for predicting protein function

Optimal enumeration of state space of finitely buffered stochastic molecular networks and exact computation of steady state landscape probability (2008)

Cao, Youfang, Liang, Jie

Abstract Background Stochasticity plays important roles in many molecular networks when molecular concentrations are in the range of 0.1 μ M to 10 n M (about 100 to 10 copies in a cell). The...

Sequence Motifs and Antimotifs in β-Barrel Membrane Proteins from a Genome-Wide Analysis: The Ala-Tyr Dichotomy and Chaperone Binding Motifs (2008)

Ronald Jackups, Sarah Cheng, Jie Liang

Integral membrane proteins can be categorized into two structural classes: α-helical proteins and βbarrel proteins. The structural properties of helical membrane proteins are well characterized,...

Optimal Block Boundary Pre/Postfiltering for Wavelet-Based Image and Video Compression (2008)

Jie Liang, Chengjie Tu, Trac D. Tran

Abstract—This paper presents a pre/postfiltering framework to reduce the reconstruction errors near block boundaries in waveletbased image and video compression. Two algorithms are developed to...

Research Focus The membrane–water interface region of membrane proteins: structural bias and the anti-snorkeling effect (2008)

Jie Liang, Larisa Adamian, Ronald Jackups

Membrane proteins have important roles in many cellular processes. Computational analysis of their sequences and structures has provided much insight into the organizing principles of transmembrane...

their functions (2008)

Larisa Adamian, Zheng Ouyang, Yan Yuan Tseng, Jie Liang

patterns of retinal-binding pockets of type I rhodopsins and

Liang J: Order independent structural alignment of circularly permuted proteins (2008)

T. Andrew Binkowski, Bhaskar Dasgupta, Jie Liang

Abstract–Circular permutation connects the N and C termini of a protein and concurrently cleaves elsewhere in the chain, providing an important mechanism for generating novel protein fold and...

Topology Independent Protein Structural Alignment (2008)

Joe Dundas, T. A. Binkowski, Bhaskar Dasgupta, Jie Liang

Abstract. Protein structural alignment is an indispensable tool used for many different studies in bioinformatics. Most structural alignment algorithms assume that the structural units of two similar...

Monte Carlo Sampling of Near-Native Structures of Proteins With Applications (2008)

Aq Jinfeng Zhang, Ming Lin, Rong Chen, Jie Liang, Jun S Liu

ABSTRACT Since a protein’s dynamic fluctuation inside cells affects the protein’s biological properties, we present a novel method to study the ensemble of near-native structures (NNS) of...

SHORT COMMUNICATION Prediction of Buried Helices in Multispan Alpha helical Membrane Proteins (2008)

Larisa Adamian, Jie Liang

ABSTRACT Analysis of a database of structures of membrane proteins shows that membrane proteins composed of 10 or more transmembrane (TM) helices often contain buried helices that are inaccessible to...

residues (2008)

Yan Yuan Tseng, Jie Liang

Predicting enzyme functional surfaces and locating key

Interstrand Pairing Patterns in b-Barrel Membrane Proteins: The Positive-outside Rule, Aromatic Rescue, and Strand Registration Prediction (2008)

Ronald Jackups, Jie Liang

Integral membrane proteins can be categorized into two structural classes: a-helical proteins and b-barrel proteins. b-Barrel proteins are found in the outer membrane of Gram-negative bacteria,...

Regulation of Glycosaminoglycan Function by Osmotic Potentials MEASUREMENT OF WATER TRANSFER DURING ANTITHROMBIN ACTIVATION BY HEPARIN* (2008)

Maria P. Mcgee, Jie Liang

The sulfated glycosaminoglycan heparin is an important anticoagulant, widely used to treat and to prevent arterial thrombosis. Heparin triggers conformational changes in, and the functional...

Protein folding dynamics in lattice model with physical movement (2008)

Sëma Kachalo, Hsiao-mei Lu, Jie Liang

Abstract — We study folding dynamcis of protein-like sequences on square lattice by constructing a physically realizable move set that exhausts all possible conformational changes for a structure....

The characteristics of lung cancer cases in 1996-2005 in Nanjing, China (2008)

Yi ZENG, Jie LIANG, Hongbing SHEN

Background and objective Epidemiology of lung cancer has changed along with the time. The aim of this study is to analyze the distribution of sex, age, pathology and smoking in the lung cancer cases...

Predicting protein folding rates from geometric contact and amino acid sequence (2008)

Ouyang, Zheng, Liang, Jie

Protein folding speeds are known to vary over more than eight orders of magnitude. Plaxco, Simons, and Baker (see References) first showed a correlation of folding speed with the topology of the...

A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women (2008)

Wang, Yan, Hu, Zhibin, Liang, Jie, Wang, Zhanwei, Tang, Jinhai, Wang, Shui, ...

Telomerase reactivation, which prevents telomere shortening and maintains cell viability, is crucial for the continued growth or progression of cancer cells. A minisatellite tandem repeat, MNS16A,...

Expression of 15-PGDH is downregulated by COX-2 in gastric cancer (2008)

Liu, Zhenxiong, Wang, Xin, Lu, Yuanyuan, Han, Shuang, Zhang, Faming, Zhai, Huihong, ...

To explore the proteins regulated by cyclooxygenase-2 (COX-2) in gastric cancer, the expression plasmid of COX-2siRNA was constructed and transfected into gastric cancer cell line SGC7901. Then,...

Genetic variants in fibroblast growth factor receptor 2 (FGFR2) contribute to susceptibility of breast cancer in Chinese women (2008)

Liang, Jie, Chen, Peizhan, Hu, Zhibin, Zhou, Xiaoyi, Chen, Lu, Li, Mian, ...

Fibroblast growth factor receptor 2 (FGFR2) belongs to the FGFR family, which plays an important role in cell growth, invasiveness, motility and angiogenesis. In human breast cancer, expression of...

A Universal Robust Low Frequency Watermarking Scheme (2007)

Jie Liang, Peng Xu, Trac D. Tran

| A novel robust low frequency digital watermarking scheme is proposed, in which the watermark is embedded in the DFT magnitude of the low frequency subband of an image. This lowpass subband can be...

Developing optimal non-linear scoring function for protein design. Bioinformatics 2004;20:3080–3098 (2007)

Changyu Hu, Xiang Li, Jie Liang

Motivation. Protein design aims to identify sequences compatible with a given protein fold but incompatible to any alternative folds. To select the correct sequences and to guide the search process,...

Potential function plays critica... (2007)

Jie Liang

Potential functions are critical for computational studies of protein structure prediction, folding, and sequence design. A class of widely used potentials for coarse grained models of proteins are...

CD34 (2007)

Ignatius Gomes, Tiffany T. Sharma, Nadim Mahmud, Seby Edassery, Noreen Fulton, Jie Liang, ...

Highly abundant genes in the transcriptosome of human and baboon

Hydration Effects of Heparin on Antithrombin Probed by Osmotic Stress (2007)

Maria P. Mcgee, Jie Liang, James Luba

ABSTRACT Antithrombin is a key inhibitor of blood coagulation proteases and a prototype metastable protein. Heparin binding to antithrombin induces conformational transitions distal to the binding...

Chloride Binding Regulates the Schiff Base pK in Gecko P521 Cone-Type Visual Pigment † (2007)

Ching Yuan, Osamu Kuwata, Jie Liang, Saurav Misra, Sergei P. Balashov, Thomas G. Ebrey

ABSTRACT: The binding of chloride is known to shift the absorption spectrum of most long-wavelengthabsorbing cone-type visual pigments roughly 30 nm to the red. We determined that the chloride...

ASSESSING EFFECT OF CROSS- HYBRIDIZATION ON OLIGONUCLEOTIDE MICROARRAYS (2007)

Seman Kachalo, Zarema Arbieva, Jie Liang

Abstract: We introduce computational method, which allows estimating the input of non-specific binding into hybridization signal intensities on the oligonucleotide-based Affymetrix GeneChip arrays....

Interhelical hydrogen bonds in transmembrane region are important for function and stability of Ca 2+-transporting ATPase (2007)

Larisa Adamian, Jie Liang

Ca 2+-transporting ATPase of sarcoplasmic reticulum couples ATP hydrolysis with ion transport. Phosphorylation of the cytosolic region of the calcium-bound conformation (E1) of the protein leads to...

RESEARCH ARTICLES Analytical Shape Computation of Macromolecules: I. Molecular Area and Volume Through Alpha Shape (2007)

Jie Liang, Herbert Edelsbrunner, Ping Fu, Pamidighantam V. Sudhakar, Shankar Subramaniam

ABSTRACT The size and shape of macromolecules such as proteins and nucleic acids play an important role in their functions. Prior efforts to quantify these properties have been based on various...

Error Resilient Pre-/Post-Filtering for DCT-based Block Coding Systems (2007)

Chengjie Tu, Trac D. Tran, Jie Liang, Student Member, Student Member

Block coding based on the Discrete Cosine Transform (DCT) is very popular in image and video compression. Pre-/post-filtering can be attached to a DCT-based block coding system to improve coding...

COMMUNICATION Are Residues in a Protein Folding Nucleus (2007)

Evolutionarily Conserved, Yan Yuan Tseng, Jie Liang

Are amino acid residues important for rapid folding preferentially conserved during evolution? Does natural selection optimize proteins for folding kinetics? If protein folding involves initially the...

pvSOAR: Detecting similar surface patterns of pocket and void surfaces of amino acid residues on proteins (2007)

T. Andrew Binkowski, Patrick Freeman, Jie Liang

Detecting similar protein surfaces provides an important route for discovering unrecognized or novel functional relationship between proteins. The webserver pvSOAR (pocket and void Surfaces Of Amino...

Topology independent protein structural alignment (2007)

Dundas, Joe, Binkowski, TA, DasGupta, Bhaskar, Liang, Jie

Abstract Background Identifying structurally similar proteins with different chain topologies can aid studies in homology modeling, protein folding, protein design, and protein evolution. These...

Research article Topology independent protein structural alignment (2007)

Joe Dundas, Ta Binkowski, Bhaskar Dasgupta, Jie Liang, Jie Liang

© 2007 Dundas et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License

A Model Study of Protein Nascent Chain and Cotranslational Folding using Hydrophobic-Polar Residues (2007)

Hsiao-mei Lu, Jie Liang

To study protein nascent chain folding during biosynthesis, we investigate the folding behavior of models of hydrophobic and polar (HP) chains at growing length using both two-dimensional square...

Filter banks for prediction-compensated multiple description coding (2007)

Jing Wang, Jie Liang

This paper investigates the design and application of the optimal filter banks for a predictioncompensated multiple description coding (PC-MDC) scheme, where the coefficients in each subband are...

Prediction of transmembrane helix orientation in polytopic membrane proteins (2006)

Adamian, Larisa, Liang, Jie

Abstract Background Membrane proteins compose up to 30% of coding sequences within genomes. However, their structure determination is lagging behind compared with soluble proteins due to the...

Experiments on the modular nature of word and sentence phonology in Chinese Broca's patients (2006)

Liang, Jie

This book investigates the effects of brain lesions in the left hemisphere (Broca’s area) on the production and perception of vowels, word tones and the linguistic use of sentence melody. We aimed...

Knowledge-based energy functions for computational studies of proteins (2006)

Li, Xiang, Liang, Jie

This chapter discusses theoretical framework and methods for developing knowledge-based potential functions essential for protein structure prediction, protein-protein interaction, and protein...

Interstrand pairing patterns in $\beta$-barrel membrane proteins: the positive-outside rule, aromatic rescue, and strand registration prediction (2006)

Jackups, Ronald, Liang, Jie

$\beta$-barrel membrane proteins are found in the outer membrane of gram-negative bacteria, mitochondria, and chloroplasts. We have developed probabilistic models to quantify propensities of residues...

Empirical Potential Function for Simplified Protein Models: Combining Contact and Local Sequence-Structure Descriptors (2006)

Zhang, Jinfeng, Chen, Rong, Liang, Jie

An effective potential function is critical for protein structure prediction and folding simulation. Simplified protein models such as those requiring only $C_\alpha$ or backbone atoms are attractive...

Computation of protein geometry and its applications: Packing and function prediction (2006)

Liang, Jie

This chapter discusses geometric models of biomolecules and geometric constructs, including the union of ball model, the weigthed Voronoi diagram, the weighted Delaunay triangulation, and the alpha...

Estimation of Amino Acid Residue Substitution Rates at Local Spatial Regions and Application in Protein Function Inference: A Bayesian Monte Carlo Approach (2006)

Tseng, Yan Y., Liang, Jie

The amino acid sequences of proteins provide rich information for inferring distant phylogenetic relationships and for predicting protein functions. Estimating the rate matrix of residue...

Protein folding dynamics via quantification of kinematic energy landscape (2006)

Kachalo, Sëma, Lu, Hsiao-Mei, Liang, Jie

We study folding dynamics of protein-like sequences on square lattice using physical move set that exhausts all possible conformational changes. By analytically solving the master equation, we follow...

BMC Structural Biology Methodology article Prediction of transmembrane helix orientation in polytopic (2006)

Membrane Proteins, Larisa Adamian, Jie Liang, Larisa Adamian, Jie Liang

Background: Membrane proteins compose up to 30 % of coding sequences within genomes. However, their structure determination is lagging behind compared with soluble proteins due to the experimental...

CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues (2006)

Dundas, Joe, Ouyang, Zheng, Tseng, Jeffery, Binkowski, Andrew, Turpaz, Yaron, Liang, Jie

Cavities on a proteins surface as well as specific amino acid positioning within it create the physicochemical properties needed for a protein to perform its function. CASTp...

Estimation of Amino Acid Residue Substitution Rates at Local Spatial Regions and Application in Protein Function Inference: A Bayesian Monte Carlo Approach (2006)

Tseng, Yan Y., Liang, Jie

The amino acid sequences of proteins provide rich information for inferring distant phylogenetic relationships and for predicting protein functions. Estimating the rate matrix of residue...

in (2005)

T. Andrew Binkowski, Andrzej Joachimiak, Jie Liang

surface analysis for function annotation

models: Combining contact and local (2005)

Jinfeng Zhang, Rong Chen, Jie Liang

Empirical potential function for simplified protein

Geometric cooperativity and anticooperativity of three-body interactions in native proteins (2005)

Xiang Li, Jie Liang

Abstract Characterizing multibody interactions of hydrophobic, polar, and ionizable residues in protein is important for understanding the stability of protein structures. We introduce a geometric...

Computational design of combinatorial peptide library for modulating protein–protein interactions. Pac Symp Biocomput 2005;28–39 (2005)

Xiang Li, Jie Liang

Screening phage-displayed combinatorial peptide library is an effective approach for discovery of peptide modulators for protein-protein interactions. However, as peptide length increases, the chance...

Empirical lipid propensities of amino acid residues in multispan alpha helical membrane proteins (2005)

Larisa Adamian, Vikas N, William F. Degrado, Jie Liang

ABSTRACT Characterizing the interactions between amino acid residues and lipid molecules is important for understanding the assembly of transmembrane helices and for studying membrane protein...

Improved Collision Attack on Hash Function MD5. Cryptology ePrint Archive (2005)

Jie Liang, Xuejia Lai

Abstract. In this paper, we present a fast attack algorithm to find two-block collision of hash function MD5. The algorithm is based on the two-block collision differential path of MD5 that was...

Estimation of Amino Acid Residue Substitution Rates at Local Spatial Regions and Application in Protein Function Inference: A Bayesian Monte Carlo Approach (2005)

Tseng, Yan Yuan, Liang, Jie

The amino acid sequences of proteins provide rich information for inferring distant phylogenetic relationships and for predicting protein functions. Estimating the rate matrix of residue...

Estimation of Amino Acid Residue Substitution Rates at Local Spatial Regions and Application in Protein Function Inference: A Bayesian Monte Carlo Approach (2005)

Tseng, Yan Yuan, Liang, Jie

The amino acid sequences of proteins provide rich information for inferring distant phylogenetic relationships and for predicting protein functions. Estimating the rate matrix of residue...

Order independent structural alignment of circularly permuted proteins (2004)

Binkowski, T. Andrew, DasGupta, Bhaskar, Liang, Jie

Circular permutation connects the N and C termini of a protein and concurrently cleaves elsewhere in the chain, providing an important mechanism for generating novel protein fold and functions....

Developing optimal nonlinear scoring function for protein design (2004)

Hu, Changyu, Li, Xiang, Liang, Jie

Motivation. Protein design aims to identify sequences compatible with a given protein fold but incompatible to any alternative folds. To select the correct sequences and to guide the search process,...

Potential function of simplified protein models for discriminating native proteins from decoys: Combining contact interaction and local sequence-dependent geometry (2004)

Zhang, Jinfeng, Chen, Rong, Liang, Jie

An effective potential function is critical for protein structure prediction and folding simulation. For simplified models of proteins where coordinates of only $C_\alpha$ atoms need to be specified,...

Importance of chirality and reduced flexibility of protein side chains: A study with square and tetrahedral lattice models (2004)

Zhang, Jinfeng, Chen, Yu, Chen, Rong, Liang, Jie

In simple models side chains are often represented implicitly (e.g., by spin-states) or simplified as one atom. We study side chain effects using square lattice and tetrahedral lattice models, with...

topoSNP: a topographic database of non-synonymous single nucleotide polymorphisms with and without known disease association (2004)

Nathan O. Stitziel, T. Andrew Binkowski, Yan Yuan Tseng, Jie Liang, Simon Kasif

The database of topographic mapping of Single Nucleotide Polymorphism (topoSNP) provides an online resource for analyzing non-synonymous SNPs (nsSNPs) that can be mapped onto known 3D structures of...

Potential Function Of Simplified Protein Models For Discriminating (2004)

Native Proteins From, Jinfeng Zhang, Rong Chen, Jie Liang

An effective potential function is critical for protein structure prediction and folding simulation. For simplified models of proteins where coordinates of only atoms need to be specified, an...

pvSOAR: Detecting similar surface patterns of pocket and void surfaces of amino acid residues on proteins (2004)

T. Andrew Binkowski, Patrick Freeman, Jie Liang

Detecting similar protein surfaces provides an important route for discovering unrecognized or novel functional relationship between proteins. The web server pvSOAR (pocket and void Surfaces Of Amino...

Developing optimal nonlinear scoring function for protein design (2004)

Hu, Changyu, Li, Xiang, Liang, Jie

Motivation: Protein design aims to identify sequences compatible with a given protein fold but incompatible to any alternative folds. To select the correct sequences and to guide the search process,...

pvSOAR: detecting similar surface patterns of pocket and void surfaces of amino acid residues on proteins (2004)

Binkowski, T. Andrew, Freeman, Patrick, Liang, Jie

Detecting similar protein surfaces provides an important route for discovering unrecognized or novel functional relationship between proteins. The web server pvSOAR (pocket and void Surfaces Of Amino...

Developing optimal non-linear scoring function for protein design (2004)

Hu, Changyu, Li, Xiang, Liang, Jie

Motivation. Protein design aims to identify sequences compatible with a given protein fold but incompatible to any alternative folds. To select the correct sequences and to guide the search process,...

topoSNP: a topographic database of non-synonymous single nucleotide polymorphisms with and without known disease association (2004)

Stitziel, Nathan O., Binkowski, T. Andrew, Tseng, Yan Yuan, Kasif, Simon, Liang, Jie

The database of topographic mapping of Single Nucleotide Polymorphism (topoSNP) provides an online resource for analyzing non‐synonymous SNPs (nsSNPs) that can be mapped onto known 3D structures...

Developing optimal nonlinear scoring function for protein design (2004)

Hu, Changyu, Li, Xiang, Liang, Jie

Motivation: Protein design aims to identify sequences compatible with a given protein fold but incompatible to any alternative folds. To select the correct sequences and to guide the search process,...

Are residues in a protein folding nucleus evolutionarily conserved? (2003)

Tseng, Yan Yuan, Liang, Jie

It is important to understand how protein folding and evolution influences each other. Several studies based on entropy calculation correlating experimental measurement of residue participation in...

Simplicial edge representation of protein structures and alpha contact potential with confidence measure (2003)

Li, Xiang, Hu, Changyu, Liang, Jie

Protein representation and potential function are essential ingredients for studying proteins folding and protein prediction. We introduce a novel geometric representation of contact interactions...

On Design of Optimal Nonlinear Kernel Potential Function for Protein Folding and Protein Design (2003)

Hu, Changyu, Li, Xiang, Liang, Jie

Potential functions are critical for computational studies of protein structure prediction, folding, and sequence design. A class of widely used potentials for coarse grained models of proteins are...

Origin of Scaling Behavior of Protein Packing Density: A Sequential Monte Carlo Study of Compact Long Chain Polymers (2003)

Zhang, Jinfeng, Chen, Rong, Tang, Chao, Liang, Jie

Single domain proteins are thought to be tightly packed. The introduction of voids by mutations is often regarded as destabilizing. In this study we show that packing density for single domain...

Simplicial edge representation of protein structures and alpha contact potential with confidence measure (2003)

Xiang Li, Changyu Hu, Jie Liang

ABSTRACT Protein representation and potential function are two important ingredients for studying protein folding, equilibrium thermodynamics, and sequence design. We introduce a novel geometric...

CASTp: Computed atlas of surface topography of proteins (2003)

T. Andrew Binkowski, Shapor Naghibzadeh, Jie Liang

Computed atlas of surface topography of proteins (CASTp) provides an online resource for locating, delineating, and measuring concave surface regions on three-dimensional structures of proteins....

Higher-order interhelical spatial interactions in membrane proteins (2003)

Larisa Adamian, Ronald Jackups, T. Andrew Binkowski, Jie Liang

Membrane proteins play essential cellular roles, including signal transduction, proton pumping, ion transport, and light harvesting. Although transmembrane (TM) helices can be predicted

Position-Dependence of Stabilizing Polar Interactions of Asparagine in Transmembrane Helical Bundles (2003)

James D. Lear, Holly Gratkowski, Larisa Adamian, Jie Liang, William F. DeGrado

Recent studies with model peptides and statistical analyses of the crystal structures of membrane proteins have shown that buried polar interactions contribute significantly to the stabilization of...

Inferring Functional Relationships of Proteins from Local Sequence and Spatial Surface Patterns (2003)

T. Andrew Binkowski, Larisa Adamian, Jie Liang

es, and for further inquiries on evolutionary origins of structural elements important for protein function. q 2003 Elsevier Ltd. All rights reserved. Keywords: protein surface; surface pattern;...

Adaptive Runlength Coding (2003)

Chengjie Tu, Jie Liang, Student Member, Student Member, Trac D. Tran

Runlength coding is the standard coding technique for block transform-based image/video compression. A block of quantized transform coefficients is first represented as a sequence of RUN/LEVEL pairs...

Lapped Transform via Time-Domain Pre- And Post-Filtering (2003)

Trac D. Tran, Jie Liang, Chengjie Tu, Student Member, Student Member

This paper presents a general framework of constructing a large family of lapped transforms with symmetric basis functions by adding simple time-domain pre- and post-processing modules onto existing...

Error resilient pre-/post-filtering for DCT-based block coding systems (2003)

Chengjie Tu, Trac D. Tran, Jie Liang

Abstract—Block coding based on the discrete cosine transform (DCT) is very popular in image and video compression. Pre/post-filtering can be attached to a DCT-based block coding system to improve...

Structural location of disease-associated singlenucleotide polymorphisms (2003)

Nathan O. Stitziel, Yan Yuan Tseng, Dimitri Pervouchine, David Goddeau, Simon Kasif, Jie Liang

Single-nucleotide polymorphisms (SNPs) are the most common form of human genetic variation. The coding regions of the human genome contain about 500,000 SNPs. 1 Among these, the nonsynonymous

FILTER BANK DESIGN FOR IMAGE/VIDEO COMPRESSION AND DIGITAL COMMUNICATIONS (2003)

Jie Liang

The growing demands for delivering multimedia services over Internet and wireless networks call for high-performance and low-complexity data compression and transmission algorithms. Various such...

CASTp: Computed Atlas of Surface Topography of proteins (2003)

Binkowski, T. Andrew, Naghibzadeh, Shapor, Liang, Jie

Computed Atlas of Surface Topography of proteins (CASTp) provides an online resource for locating, delineating and measuring concave surface regions on three-dimensional structures of proteins. These...

STUDY OF THE EFFECTIVENESS OF A WEB-BASED INTERACTIVE HOMEWORK (2002)

Liang, Jie

With increased use of the web in teaching there is growing interest in the effectiveness of web-based tools in facilitating student learning. I have conducted a case study on the effectiveness of...

STUDY OF THE EFFECTIVENESS OF A WEB-BASED INTERACTIVE HOMEWORK (2002)

Liang, Jie

With increased use of the web in teaching there is growing interest in the effectiveness of web-based tools in facilitating student learning. I have conducted a case study on the effectiveness of...

Statistical Geometry of Packing Defects of Lattice Chain Polymer from Enumeration and Sequential Monte Carlo Method (2002)

Liang, Jie, Zhang, Jinfeng, Chen, Rong

Voids exist in proteins as packing defects and are often associated with protein functions. We study the statistical geometry of voids in two-dimensional lattice chain polymers. We define voids as...

Study of the effectiveness of a web-based interactive homework (2002)

Liang, Jie.

Thesis (M.S.)--Mississippi State University. Department of Physics and Astronomy.

Study of the effectiveness of a web-based interactive homework [electronic resource] / (2002)

Liang, Jie.

With increased use of the web in teaching there is growing interest in the effectiveness of web-based tools in facilitating student learning. I have conducted a case study on the effectiveness of...

Study of the effectiveness of a web-based interactive homework (2002)

Liang, Jie.

Thesis (M.S.)--Mississippi State University. Department of Physics and Astronomy.

DCT-based general structure for linear phase paraunitary filter banks (2002)

Paraunitary Filterbanks, Jie Liang, Student Member, Trac D. Tran, Senior Member

Abstract—In this paper, we present a general structure for linear phase paraunitary filterbanks (LPPUFB) via both time-domain pre-processing and frequency-domain post-processing of the discrete...

Further results on DCT-based linear phase paraunitary filter banks (2002)

Jie Liang, Trac D. Tran

A DCT-based simplified general structure for linear phase paraunitary filter bank (LPPUFB) is developed recently by the pre- and post-processing of the DCT in the time domain. The new structure can...

Helix-helix packing and interfacial pairwise interactions of residues in membrane proteins (2001)

Larisa Adamian, Jie Liang

Integral membrane proteins play essential cellular roles, including signal transduction, proton pumping, ion transport, and light harvesting. They are abundantly found and account for about 20-

Are proteins well-packed (2001)

Jie Liang, Ken A. Dill

ABSTRACT The average packing density inside proteins is as high as in crystalline solids. Does this mean proteins are well-packed? We go beyond average densities, and look at the full distribution...

Fast Multiplierless Approximations of the DCT with the Lifting Scheme (2001)

Jie Liang, Trac D. Tran

Abstract|In this paper, we present the design, implementation and application of several families of fast multiplierless approximations of the discrete cosine transform (DCT) with the lifting scheme,...

Fast Multiplierless Approximations of the DCT with the Lifting Scheme (2001)

Jie Liang, Student Member, Trac D. Tran

In this paper, we present the design, implementation, and application of several families of fast multiplierless approximations of the discrete cosine transform (DCT) with the lifting scheme called...

Fast Multiplierless Approximation of the DCT with the Lifting Scheme (2000)

Jie Liang, Trac D. Tran

In this paper, we present a systematic approach to design two families of fast multiplierless approximations of the DCT with the lifting scheme, based on two kinds of factorizations of the DCT matrix...

1 Digital Photography Market Overview Contents (2000)

Wissam Rabadi, Raj Talluri, Klaus Illgner, Jie Liang, Youngjun Yoo

Digital Still Camera Business Unit This article presents a programmable digital signal processor (DSP) platform for digital still cameras based on the Texas Instruments TMS320C54x family. One major...

New Trends in Multimedia Standards: MPEG4 and JPEG2000 (1999)

Jie Liang

The dramatic increase in both computational power, brought on by the introduction of increasingly powerful chips, and the communications bandwidth, unleashed by the introduction of cable modem and...

New Trends in Multimedia Standards: MPEG4 and JPEG2000 (1999)

Jie Liang

The dramatic increase in both computational power, brought on by the introduction of increasingly powerful chips, and the communications bandwidth, unleashed by the introduction of cable modem and...

Analytical shape computing of macromolecules II: identification and computation of inaccessible cavities inside proteins (1998)

Jie Liang, Herbert Edelsbrunner, Ping Fu, Pamidighantam V. Sudhakar, Shankar Subramaniam

ABSTRACT The structures of proteins are well-packed, yet they contain numerous cavities which play key roles in accommodating small molecules, or enabling conformational changes. From high-resolution...

Hydration structure of antithrombin conformers and water transfer during reactive loop insertion (1998)

Jie Liang, Maria P. Mcgee

ABSTRACT The serine protease inhibitor antithrombin undergoes extensive conformational changes during functional interaction with its target proteases. Changes include insertion of the reactive loop...

Analytical shape computing of macromolecules I: Molecular area and volume through alpha-shape (1998)

Jie Liang, Herbert Edelsbrunner, Ping Fu, Pamidighantam V. Sudhakar, Shankar Subramaniam

ABSTRACT The structures of proteins are well-packed, yet they contain numerous cavities which play key roles in accommodating small molecules, or enabling conformational changes. From high-resolution...

Computation of molecular electrostatics with boundary element methods (1997)

Jie Liang, Shankar Subramaniam

ABSTRACT In continuum approaches to molecular electrostatics, the boundary element method (BEM) can provide accurate solutions to the Poisson-Boltzmann equation. However, the numerical aspects of...

Early Photolysis Intermediates of Gecko and Bovine Artificial Visual Pigments † (1997)

James W. Lewis, Jie Liang, Thomas G. Ebrey, Mordechai Sheves, Nurit Livnah, Osamu Kuwata, ...

pigments prepared from the cone-type visual pigment, P521, of the Tokay gecko (Gekko gekko) retina. Artificial pigments were prepared by regeneration of bleached gecko photoreceptor membranes with...

Numerical Computing of Molecular Electrostatics through Boundary Integral Equations (1996)

Jie Liang, Shankar Subramaniam

this paper, we apply accurate methods to compute molecular shapes for use in BEM electrostatics calculations. We also determine the desired formulation of BEM which has the advantage of numerical...

Measuring proteins and voids in proteins (1995)

Herbert Edelsbrunner, Michael Face, Ping Fu, Jie Liang

Common geometric models for proteins and other molecules are the space filling diagram, the solvent ac-cessible surface, and the molecular surface. We descnbe software that compules metric properties...

On the Definition and the Construction of Pockets in Macromolecules (1995)

Herbert Edelsbrunner, Michael Facello, Jie Liang

The shape of a protein is important for its functions. This includes the location and size of identifiable regions in its complement space. We formally define pockets as regions in the complement...

Chloride Effect on the Early Photolysis Intermediates of a Gecko Cone-Type Visual Pigment+ (1994)

James W. Lewis, Jie Liang, Thomas G. Ebrey, Mordechai Sheves, David S. Kliger

ABSTRACT: Nanosecond laser photolysis measurements were conducted on the cone-type visual pigment P521 in digitonin extracts of Tokay gecko (Gekko gekko) retina containing physiological chloride ion...

Metarhodopsin Intermediates of the Gecko Cone Pigment P521t (1993)

Jie Liang, Rajni Govindjee, Thomas G. Ebrey

ABSTRACT: Cone visual pigments are responsible for color vision. Using low-temperature spectroscopy and linear/logarithmic time scale flash photolysis, we studied the photochemistry of the cone...

Equidistant binary arithmetic codes (1986)

Jie Liang, Range Cdf, J. Liang, J. Liang, J. Liang, J. Liang, ...

� Arithmetic coding is slow in general: To decode a symbol, we need a series of decisions and multiplications: While (Tag> LOW + RANGE * Sum(n) / N- 1) { n++; � The complexity is greatly...

Chemical complementation identifies a proton acceptor for redox-active tyrosine D in photosystem II

Kim, Sunyoung, Liang, Jie, Barry, Bridgette A.

Through the use of site-directed mutagenesis and chemical rescue, we have identified the proton acceptor for redox-active tyrosine D in photosystem II (PSII). Effects of chemical rescue on the...

CASTp: Computed Atlas of Surface Topography of proteins

Binkowski, T. Andrew, Naghibzadeh, Shapor, Liang, Jie

Computed Atlas of Surface Topography of proteins (CASTp) provides an online resource for locating, delineating and measuring concave surface regions on three-dimensional structures of proteins. These...

topoSNP: a topographic database of non-synonymous single nucleotide polymorphisms with and without known disease association

Stitziel, Nathan O., Binkowski, T. Andrew, Tseng, Yan Yuan, Kasif, Simon, Liang, Jie

The database of topographic mapping of Single Nucleotide Polymorphism (topoSNP) provides an online resource for analyzing non-synonymous SNPs (nsSNPs) that can be mapped onto known 3D structures of...

pvSOAR: detecting similar surface patterns of pocket and void surfaces of amino acid residues on proteins

Binkowski, T. Andrew, Freeman, Patrick, Liang, Jie

Detecting similar protein surfaces provides an important route for discovering unrecognized or novel functional relationship between proteins. The web server pvSOAR (pocket and void Surfaces Of Amino...

The DNA Architectural Protein HMGB1 Facilitates RTA-Mediated Viral Gene Expression in Gamma-2 Herpesviruses

Jung Song, Moon, Hwang, Seungmin, Wong, Wendy, Round, June, Martinez-Guzman, DeeAnn, Turpaz, Yaron, ...

Replication and transcription activator (RTA), an immediate-early gene product of gamma-2 herpesviruses including Kaposi's sarcoma-associated herpesvirus (KSHV) and murine gamma herpesvirus 68...

Hydration effects of heparin on antithrombin probed by osmotic stress.

McGee, Maria P, Liang, Jie, Luba, James

Antithrombin is a key inhibitor of blood coagulation proteases and a prototype metastable protein. Heparin binding to antithrombin induces conformational transitions distal to the binding site. We...

CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues

Dundas, Joe, Ouyang, Zheng, Tseng, Jeffery, Binkowski, Andrew, Turpaz, Yaron, Liang, Jie

Cavities on a proteins surface as well as specific amino acid positioning within it create the physicochemical properties needed for a protein to perform its function. CASTp () is an online tool that...

Chemical complementation identifies a proton acceptor for redox-active tyrosine D in photosystem II

Kim, Sunyoung, Liang, Jie, Barry, Bridgette A.

Through the use of site-directed mutagenesis and chemical rescue, we have identified the proton acceptor for redox-active tyrosine D in photosystem II (PSII). Effects of chemical rescue on the...

CASTp: Computed Atlas of Surface Topography of proteins

Binkowski, T. Andrew, Naghibzadeh, Shapor, Liang, Jie

Computed Atlas of Surface Topography of proteins (CASTp) provides an online resource for locating, delineating and measuring concave surface regions on three-dimensional structures of proteins. These...

topoSNP: a topographic database of non-synonymous single nucleotide polymorphisms with and without known disease association

Stitziel, Nathan O., Binkowski, T. Andrew, Tseng, Yan Yuan, Kasif, Simon, Liang, Jie

The database of topographic mapping of Single Nucleotide Polymorphism (topoSNP) provides an online resource for analyzing non-synonymous SNPs (nsSNPs) that can be mapped onto known 3D structures of...

pvSOAR: detecting similar surface patterns of pocket and void surfaces of amino acid residues on proteins

Binkowski, T. Andrew, Freeman, Patrick, Liang, Jie

Detecting similar protein surfaces provides an important route for discovering unrecognized or novel functional relationship between proteins. The web server pvSOAR (pocket and void Surfaces Of Amino...

The DNA Architectural Protein HMGB1 Facilitates RTA-Mediated Viral Gene Expression in Gamma-2 Herpesviruses

Jung Song, Moon, Hwang, Seungmin, Wong, Wendy, Round, June, Martinez-Guzman, DeeAnn, Turpaz, Yaron, ...

Replication and transcription activator (RTA), an immediate-early gene product of gamma-2 herpesviruses including Kaposi's sarcoma-associated herpesvirus (KSHV) and murine gamma herpesvirus 68...

Hydration effects of heparin on antithrombin probed by osmotic stress.

McGee, Maria P, Liang, Jie, Luba, James

Antithrombin is a key inhibitor of blood coagulation proteases and a prototype metastable protein. Heparin binding to antithrombin induces conformational transitions distal to the binding site. We...

CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues

Dundas, Joe, Ouyang, Zheng, Tseng, Jeffery, Binkowski, Andrew, Turpaz, Yaron, Liang, Jie

Cavities on a proteins surface as well as specific amino acid positioning within it create the physicochemical properties needed for a protein to perform its function. CASTp () is an online tool that...

Protein surface analysis for function annotation in high-throughput structural genomics pipeline

Binkowski, T. Andrew, Joachimiak, Andrzej, Liang, Jie

Structural genomics (SG) initiatives are expanding the universe of protein fold space by rapidly determining structures of proteins that were intentionally selected on the basis of low sequence...

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Nathan O. Stitziel, Yan Yuan Tseng, Dimitri Pervouchine, David Goddeau, Simon Kasif, Jie Liang

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Predicting protein folding rates from geometric contact and amino acid sequence

Ouyang, Zheng, Liang, Jie

Protein folding speeds are known to vary over more than eight orders of magnitude. Plaxco, Simons, and Baker (see References) first showed a correlation of folding speed with the topology of the...

Generating properly weighted ensemble of conformations of proteins from sparse or indirect distance constraints

Lin, Ming, Lu, Hsiao-Mei, Chen, Rong, Liang, Jie

Inferring three-dimensional structural information of biomacromolecules such as proteins from limited experimental data is an important and challenging task. Nuclear Overhauser effect measurements...

Perturbation-based Markovian Transmission Model for Probing Allosteric Dynamics of Large Macromolecular Assembling: A Study of GroEL-GroES

Lu, Hsiao-Mei, Liang, Jie

Large macromolecular assemblies are often important for biological processes in cells. Allosteric communications between different parts of these molecular machines play critical roles in cellular...