Jie Zheng

Publication List Details

Period

1994 - 2008

Number

38

Co-Authors

Apoptosis and Aging in Drosophila (2008)

Zheng, JIE

Thesis (Ph.D, Biology) -- Queen's University, 2008-10-27 00:24:02.204

Campylobacter jejuni/coli - Host Intestinal Epithelial Cell Interaction (2006)

Zheng, Jie

Campylobacter jejuni/coli have been known to be major bacterial causes of human gastroenteritis worldwide for decades. Regarding its pathogenicity, little is known yet. A better understanding of the...

Designing a Nanotube Using Naturally Occurring Protein Building Blocks (2006)

Chung-Jung Tsai, Jie Zheng, Ruth Nussinov

Here our goal is to carry out nanotube design using naturally occurring protein building blocks. Inspection of the protein structural database reveals the richness of the conformations of proteins,...

Development of chiral/achiral analysis methods using capillary electrochromatography and capillary electrochromatography coupled to mass spectrometry [electronic resource] / (2006)

Zheng, Jie.

The research presented in this dissertation involves the development of chiral and achiral analysis using capillary electrochromatography (CEC) and CEC coupled to mass spectrometry (CEC-MS). Chapter...

Differential patterns of apoptosis in response to aging in Drosophila (2005)

Zheng, Jie, Edelman, Scott W., Tharmarajah, Grace, Walker, David W., Pletcher, Scott D., Seroude, Laurent

Several lines of evidence suggest that programmed cell death may play a role in the aging process and the age-related functional declines of multicellular organisms. To pave the way for the use of...

Fluorescent noble metal nanoclusters (2005)

Zheng, Jie

Water-soluble fluorescent metallic clusters at sizes comparable to the Fermi wavelength of an electron (~0.5 nm for gold and silver) were created and their photophysical properties were investigated...

Fluorescent noble metal nanoclusters [electronic resource] / (2005)

Zheng, Jie.

Water-soluble fluorescent metallic clusters at sizes comparable to the Fermi wavelength of an electron (~0.5 nm for gold and silver) were created and their photophysical properties were investigated...

Fluorescent noble metal nanoclusters (2005)

Zheng, Jie.

Thesis (Ph. D.)--Chemistry and Biochemistry, Georgia Institute of Technology, 2005.

EFFECTS OF CAPILLARITY ON THE MECHANICAL STABILITY OF SMALL-SCALE INTERFACES (2004)

Zheng, Jie

Interfacial adhesion and friction are significant factors in determining the reliability of small-scale mechanical devices such as with MEMS and the computer head/disk interface (HDI). As the...

Effects of capillarity on the mechanical stability of small-scale interfaces [electronic resource] / (2004)

Zheng, Jie.

Interfacial adhesion and friction are significant factors in determining the reliability of small-scale mechanical devices such as with MEMS and the computer head/disk interface (HDI). As the...

Effects of capillarity on the mechanical stability of small-scale interfaces (2004)

Zheng, Jie.

Thesis (Ph. D.)--Mechanical Engineering, Georgia Institute of Technology, 2005.

Synthesis and Characterization of Conjugated Mono- and Dithiol Oligomers and Characterization of Their Self-Assembled Monolayers (2003)

Boer, Bert De, Meng, Hong, Perepichka, Dmitrii F., Zheng, Jie, Frank, Martin M., Chabal, Yves J., ...

The characterization of self-assembled monolayer molecular arrays, which serve as active layers in electronic devices, is an important step toward understanding molecular-scale electronics. To...

Stirred media mills: Dynamics, performance, and physio-chemical aspects (1997)

Zheng, Jie

While applications of stirred media mills for fine particle production have continued to grow, there is a lack of understanding of power requirements, optimum operating conditions and powder...

Threshold management strategies for exploited fish populations / (1994)

Zheng, Jie.

Thesis (Ph. D.)--University of Alaska Fairbanks, 1994.

Thermosensitive TRPV Channel Subunits Coassemble into Heteromeric Channels with Intermediate Conductance and Gating Properties

Cheng, Wei, Yang, Fan, Takanishi, Christina L., Zheng, Jie

Heat-sensitive transient receptor potential (TRP) channels (TRPV1–4) form the major cellular sensors for detecting temperature increases. Homomeric channels formed by thermosensitive TRPV subunits...

Multiple organ infection and the pathogenesis of SARS

Gu, Jiang, Gong, Encong, Zhang, Bo, Zheng, Jie, Gao, Zifen, Zhong, Yanfeng, ...

After >8,000 infections and >700 deaths worldwide, the pathogenesis of the new infectious disease, severe acute respiratory syndrome (SARS), remains poorly understood. We investigated 18 autopsies of...

Structural features of the focal adhesion kinase–paxillin complex give insight into the dynamics of focal adhesion assembly

Bertolucci, Craig M., Guibao, Cristina D., Zheng, Jie

The C-terminal region of focal adhesion kinase (FAK) consists of a right-turn, elongated, four-helix bundle termed the focal adhesion targeting (FAT) domain. The structure of this domain is...

Role of the S3-S4 Linker in Shaker Potassium Channel Activation

Mathur, Rajesh, Zheng, Jie, Yan, Yangyang, Sigworth, Fred J.

Structural models of voltage-gated channels suggest that flexibility of the S3-S4 linker region may be important in allowing the S4 region to undergo large conformational changes in its putative...

Intermediate Conductances during Deactivation of Heteromultimeric Shaker Potassium Channels

Zheng, Jie, Sigworth, Fred J.

A previous study of the T442S mutant Shaker channel revealed activation-coupled subconductance levels that apparently represent kinetic intermediates in channel activation (Zheng, J., and F.J....

Selectivity Changes during Activation of Mutant Shaker Potassium Channels

Zheng, Jie, Sigworth, Fred J.

Mutations of the pore-region residue T442 in Shaker channels result in large effects on channel kinetics. We studied mutations at this position in the backgrounds of NH2-terminal–truncated Shaker...

Hidden Markov Model Analysis of Intermediate Gating Steps Associated with the Pore Gate of Shaker Potassium Channels

Zheng, Jie, Vankataramanan, Lalitha, Sigworth, Fred J.

Cooperativity among the four subunits helps give rise to the remarkable voltage sensitivity of Shaker potassium channels, whose open probability changes tenfold for a 5-mV change in membrane...

Changing the Charge Distribution of β-Helical-Based Nanostructures Can Provide the Conditions for Charge Transfer

Haspel, Nurit, Zanuy, David, Zheng, Jie, Aleman, Carlos, Wolfson, Haim, Nussinov, Ruth

In this work we present a computational approach to the design of nanostructures made of structural motifs taken from left-handed β-helical proteins. Previously, we suggested a structural model...

Models of β-Amyloid Ion Channels in the Membrane Suggest That Channel Formation in the Bilayer Is a Dynamic Process

Jang, Hyunbum, Zheng, Jie, Nussinov, Ruth

Here we model the Alzheimer β-peptide ion channel with the goal of obtaining insight into the mechanism of amyloid toxicity. The models are built based on NMR data of the oligomers, with the...

Modeling the Alzheimer Aβ17-42 Fibril Architecture: Tight Intermolecular Sheet-Sheet Association and Intramolecular Hydrated Cavities

Zheng, Jie, Jang, Hyunbum, Ma, Buyong, Tsai, Chung-Jun, Nussinov, Ruth

We investigate Aβ17-42 protofibril structures in solution using molecular dynamics simulations. Recently, NMR and computations modeled the Aβ protofibril as a longitudinal stack of U-shaped...