Jielin Pu

Readthrough of nonsense mutation W822X in the SCN5A gene can effectively restore expression of cardiac Na+ channels (2009)

Teng, Siyong, Gao, Lizhi, Paajanen, Vesa, Pu, Jielin, Fan, Zheng

Aims Nonsense mutations in the SCN5A gene result in truncated, non-functional derivatives of the cardiac Na+ channel and thus cause arrhythmias. Studies of other genes suggest that pathogenic...

Perioperative anticoagulation for patients with mechanic heart valve(s) undertaking pacemaker implantation (2009)

Cheng, Min, Hua, Wei, Chen, Keping, Pu, Jielin, Ren, Xiaoqing, Zhao, Xinran, ...

Aims This study was to evaluate perioperative anticoagulation therapy in patients with mechanic heart valve(s) undergoing pacemaker implantation. Methods and resluts A total of 109 patients with...

Density and function of inward currents in right atrial cells from chronically fibrillating canine atria (2002)

Yagi, Takuya, Pu, Jielin, Chandra, Parag, Hara, Motoki, Danilo, Peter, Rosen, Michael R, ...

Objective: To determine whether INa and ICaL are altered in function/density in right atrial (RA) cells from dogs with chronic atrial fibrillation (cAF dogs, episodes lasting at least 6 days) and...

Disruption of Sur2-containing KATP channels enhances insulin-stimulated glucose uptake in skeletal muscle

Chutkow, William A., Samuel, Varman, Hansen, Polly A., Pu, Jielin, Valdivia, Carmen R., Makielski, Jonathan C., ...

ATP-sensitive potassium channels (KATP) are involved in a diverse array of physiologic functions including protection of tissue against ischemic insult, regulation of vascular tone, and modulation of...

Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 KATP channels

Chutkow, William A., Pu, Jielin, Wheeler, Matthew T., Wada, Tomoyuki, Makielski, Jonathan C., Burant, Charles F., ...

KATP channels couple the intracellular energy state to membrane excitability and regulate a wide array of biologic activities. KATP channels contain a pore-forming inwardly rectifying potassium...

Disruption of Sur2-containing KATP channels enhances insulin-stimulated glucose uptake in skeletal muscle

Chutkow, William A., Samuel, Varman, Hansen, Polly A., Pu, Jielin, Valdivia, Carmen R., Makielski, Jonathan C., ...

ATP-sensitive potassium channels (KATP) are involved in a diverse array of physiologic functions including protection of tissue against ischemic insult, regulation of vascular tone, and modulation of...

Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 KATP channels

Chutkow, William A., Pu, Jielin, Wheeler, Matthew T., Wada, Tomoyuki, Makielski, Jonathan C., Burant, Charles F., ...

KATP channels couple the intracellular energy state to membrane excitability and regulate a wide array of biologic activities. KATP channels contain a pore-forming inwardly rectifying potassium...