Jim Van Os

Bipolar disorder and dopamine dysfunction: an indirect approach focusing on tardive movement syndromes in a naturalistic setting (2009)

Van Rossum, Inge, Tenback, Diederik, Van Os, Jim

Abstract Background It has been suggested that dopamine dysfunction may play a role in bipolar disorder (BD). An indirect approach to examine this issue was developed, focusing on associations...

Are women better mindreaders? Sex differences in neural correlates of mentalizing detected with functional MRI (2009)

Krach, Sören, Blümel, Isabelle, Marjoram, Dominic, Lataster, Tineke, Krabbendam, Lydia, Weber, Jochen, ...

Abstract Background The ability to mentalize, i.e. develop a Theory of Mind (ToM), enables us to anticipate and build a model of the thoughts, emotions and intentions of others. It has long been...

A real-life observational study of the effectiveness of FACT in a Dutch mental health region (2008)

Drukker, Marjan, Maarschalkerweerd, Myrte, Bak, Maarten, Driessen, Ger, à Campo, Joost, De Bie, Arthur, ...

Abstract Background ACT is an effective community treatment but causes discontinuity of care between acutely ill and currently stable patient groups. The Dutch variant of ACT, FACT, combines both...

Executive function does not predict coping with symptoms in stable patients with a diagnosis of schizophrenia (2008)

Bak, Maarten, Krabbendam, Lydia, Delespaul, Philippe, Huistra, Karola, Walraven, Wil, Van Os, Jim

Abstract Background Associations between coping with and control over psychotic symptoms were examined using the Maastricht Assessment of Coping Strategies-24, testing the hypothesis that the...

Susceptibility to depression expressed as alterations in cortisol day curve: a cross-twin, cross-trait study (2008)

Myin-Germeys, Inez, Jacobs, Nele, Kenis, Gunter, ...

OBJECTIVE: To examine, using a cross-twin cross-trait design, the hypotheses 1) that the genetic and environmental susceptibility to depression is expressed, in part, as alterations in cortisol day...

Evidence that the COMT(Val158Met) polymorphism moderates sensitivity to stress in psychosis: an experience-sampling study (2008)

Henquet, Cécile, Rosa, Araceli, Papiol, Sergi, Fananás, Lourdes, ...

Gene-environment interactions involving the catechol-O-methyltransferase Val(158)Met polymorphism (COMT(Val158Met)) have been implicated in the causation of psychosis. Evidence from general...

Psychiatric diagnosis as an independent risk factor for metabolic disturbances: results from a comprehensive, naturalistic screening program. (2008)

Van Winkel, Ruud, Van Os, Jim, Celic, Ivan, Van Eyck, Dominique, Wampers, Martien, Scheen, André, ...

OBJECTIVE: Unconfounded differences in inherent vulnerability to metabolic disturbance may be hypothesized for different diagnostic groups with severe mental illness. METHOD: A naturalistic cohort of...

Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions (2008)

Van Os, Jim, Rutten, Bart PF, Poulton, Richie

Concern is building about high rates of schizophrenia in large cities, and among immigrants, cannabis users, and traumatized individuals, some of which likely reflects the causal influence of...

Deconstructing Psychosis Conference February 2006: The Validity of Schizophrenia and Alternative Approaches to the Classification of Psychosis (2007)

Allardyce, Judith, Gaebel, Wolfgang, Zielasek, Jurgen, Van Os, Jim

The DSM V planning process is currently underway and it has once again ignited the debate about the validity of the schizophrenia diagnosis. In this paper, we review the psychometric literature...

Premorbid IQ as a predictor for the course of IQ in first onset patients with schizophrenia: A 10-year follow-up study (2006)

Myin-Germeys, Inez, Delespaul, Philippe, Van Os, Jim

The aim of the present study was to examine the longitudinal course of IQ and its heterogeneity in patients with schizophrenia, from the perspective of the two main "subtypes" of schizophrenia...

Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression (2006)

Kenis, Gunter, Peeters, Frenk, Van Os, Jim

CONTEXT: Genetic moderation of the depression-inducing effects of stressful life events (SLEs) has been reported, but findings suggest that genes may not moderate the effects of SLEs per se but...

The wider social environment and changes in self-reported quality of life in the transition from late childhood to early adolescence: a cohort study (2006)

Drukker, Marjan, Kaplan, Charles, Schneiders, Josien, Feron, Frans JM, Van Os, Jim

Abstract Background Neighbourhood socioeconomic disadvantage and social capital have been associated with adolescent well-being, but the majority of studies were cross-sectional, and the time window...

Genes making one feel blue in the flow of daily life: a momentary assessment study of gene-stress interaction (2006)

Rijsdijk, Fruhling, Delespaul, Phillipe, Van Os, Jim, ...

OBJECTIVE: Individual differences in stress reactivity constitute a crucially important mechanism of risk for depression. Because stress can be conceptualized as the continuous occurrence of minor...

Data Gathering: Biased in Psychosis? (2006)

Van Dael, Frank, Versmissen, Dagmar, Janssen, Ilse, Myin-Germeys, Inez, Van Os, Jim, Krabbendam, Lydia

This study examined whether the probabilistic reasoning bias referred to as a “jumping-to-conclusions” (JTC) style of reasoning, which, according to previous research, is associated with...

The Environment and Schizophrenia: The Role of Cannabis Use (2005)

Henquet, Cécile, Murray, Robin, Linszen, Don, Van Os, Jim

Cannabis use is associated with poor outcome in existing schizophrenia and may precipitate psychosis in individuals with preexisting liability. To investigate the overall effect size and consistency...

Schizophrenia and Urbanicity: A Major Environmental Influence--Conditional on Genetic Risk (2005)

Krabbendam, Lydia, Van Os, Jim

More than 10 studies have consistently shown that around one-third of all schizophrenia incidence may be related to unknown but likely unconfounded environmental factors operating in the urban...

Data Gathering: Biased in Psychosis? (2005)

Van Dael, Frank, Versmissen, Dagmar, Janssen, Ilse, Myin-Germeys, Inez, Van Os, Jim, Krabbendam, Lydia

This study examined whether the probabilistic reasoning bias referred to as a "jumping-to-conclusions" (JTC) style of reasoning, which, according to previous research, is associated with particular...

Schizophrenia and Urbanicity: A Major Environmental Influence--Conditional on Genetic Risk (2005)

Krabbendam, Lydia, Van Os, Jim

More than 10 studies have consistently shown that around one-third of all schizophrenia incidence may be related to unknown but likely unconfounded environmental factors operating in the urban...

The Environment and Schizophrenia: The Role of Cannabis Use (2005)

Henquet, Cécile, Murray, Robin, Linszen, Don, Van Os, Jim

Cannabis use is associated with poor outcome in existing schizophrenia and may precipitate psychosis in individuals with preexisting liability. To investigate the overall effect size and consistency...

The Environment and Schizophrenia: The Role of Cannabis Use (2005)

Henquet, Cécile, Murray, Robin, Linszen, Don, Van Os, Jim

Cannabis use is associated with poor outcome in existing schizophrenia and may precipitate psychosis in individuals with preexisting liability. To investigate the overall effect size and consistency...

Schizophrenia and Urbanicity: A Major Environmental Influence--Conditional on Genetic Risk (2005)

Krabbendam, Lydia, Van Os, Jim

More than 10 studies have consistently shown that around one-third of all schizophrenia incidence may be related to unknown but likely unconfounded environmental factors operating in the urban...

Data Gathering: Biased in Psychosis? (2005)

Van Dael, Frank, Versmissen, Dagmar, Janssen, Ilse, Myin-Germeys, Inez, Van Os, Jim, Krabbendam, Lydia

This study examined whether the probabilistic reasoning bias referred to as a "jumping-to-conclusions" (JTC) style of reasoning, which, according to previous research, is associated with particular...

Abnormal response to metabolic stress in schizophrenia: marker of vulnerability or acquired sensitization? (2004)

Marcelis, Machteld, Cavalier, Etienne, Gielen, Jacques, Delespaul, Philippe, Van Os, Jim

Background. Previous work suggests that individuals with schizophrenia display an altered homovanillic acid (HVA) response to metabolic stress. The present study replicated and extended this...

When Does Experience of Psychosis Result in a Need for Care? A Prospective General Population Study (2003)

Bak, Maarten, Myin-Germeys, Inez, Hanssen, Manon, Bijl, Rob, Vollebergh, Wilma, Delespaul, Philippe, ...

Not all individuals with experience of psychosis develop a need for care. The present study investigated differences in coping strategies and associated levels of perceived control over psychotic...

Further Evidence That Congenital Dermatoglyphic Abnormalities Are Associated With Psychosis: A Twin Study (2002)

Rosa, Araceli, Fañanás, Lourdes, Van Os, Jim, Ribchester, Tracy, Davies, Nadia, Arias, Bárbara, ...

The presence of abnormal palmar flexion creases (APFC) and dermatoglyphic ridge dissociation (RD) may constitute enduring evidence of a prenatal insult that occurred before the third trimester of...

Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people

Henquet, Cécile, Krabbendam, Lydia, Spauwen, Janneke, Kaplan, Charles, Lieb, Roselind, Wittchen, Hans-Ulrich, ...

Objective To investigate the relation between cannabis use and psychotic symptoms in individuals with above average predisposition for psychosis who first used cannabis during adolescence.

Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people

Henquet, Cécile, Krabbendam, Lydia, Spauwen, Janneke, Kaplan, Charles, Lieb, Roselind, Wittchen, Hans-Ulrich, ...

Objective To investigate the relation between cannabis use and psychotic symptoms in individuals with above average predisposition for psychosis who first used cannabis during adolescence.

Data Gathering: Biased in Psychosis?

Van Dael, Frank, Versmissen, Dagmar, Janssen, Ilse, Myin-Germeys, Inez, Van Os, Jim, Krabbendam, Lydia

This study examined whether the probabilistic reasoning bias referred to as a “jumping-to-conclusions” (JTC) style of reasoning, which, according to previous research, is associated with...

Deconstructing Psychosis Conference February 2006: The Validity of Schizophrenia and Alternative Approaches to the Classification of Psychosis

Allardyce, Judith, Gaebel, Wolfgang, Zielasek, Jurgen, Van Os, Jim

The DSM V planning process is currently underway and it has once again ignited the debate about the validity of the schizophrenia diagnosis. In this paper, we review the psychometric literature...

Does the Concept of “Sensitization” Provide a Plausible Mechanism for the Putative Link Between the Environment and Schizophrenia?

Collip, Dina, Myin-Germeys, Inez, Van Os, Jim

Previous evidence reviewed in Schizophrenia Bulletin suggests the importance of a range of different environmental factors in the development of psychotic illness. It is unlikely, however, that the...

Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions

Van Os, Jim, Rutten, Bart PF, Poulton, Richie

Concern is building about high rates of schizophrenia in large cities, and among immigrants, cannabis users, and traumatized individuals, some of which likely reflects the causal influence of...