Jinfeng Liu

Summary (2009)

Jinfeng Liu, Burkhard Rost

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Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective (2008)

Liu, Jinfeng, Zhang, Yan, Lei, Xingye, Zhang, Zemin

Abstract Background The rates of molecular evolution for protein-coding genes depend on the stringency of functional or structural constraints. The Ka/Ks ratio has been commonly used as an indicator...

2 Battery Emulation B#: A Battery Emulator and Power-Profiling Instrument (2008)

Chulsung Park, Jinfeng Liu, Pai H. Chou

B # (B sharp) is a programmable power supply that emulates battery behavior. It measures current load, calls a battery simulation program to compute voltage in real time, and controls a linear...

General Terms (2008)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

communication speed selection, communication/computation trade-offs, embedded multi-processor, lowpower design This paper presents a new technique for global energy optimization through coordinated...

Power-Aware Task Motion for Enhancing Dynamic Range of Embedded Systems with Renewable Energy Sources (2008)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

Abstract. New embedded systems are being built with new types of energy sources, including solar panels and energy scavenging devices, in order to maximize their utility when battery or A/C power is...

Power-Aware Task Motion for Enhancing Dynamic Range of Embedded Systems with Renewable Energy Sources (2007)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

Abstract. New embedded systems are being built with new types of energy sources, including solar panels and energy scavenging devices, in order to maximize their utility when battery and A/C power...

Energy Optimization of Distributed Pipelined Processors by Combined Data Compression and Functional Partitioning (2007)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

Transmitting compressed data can reduce inter-processor communication traffic and create new opportunities for DVS (dynamic voltage scaling) in distributed embedded systems. However, data compression...

General Terms (2007)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

communication speed selection, communication/computation trade-offs, embedded multi-processor, lowpower design This paper presents a new technique for global energy optimization through coordinated...

ABSTRACT A Constraint-based Application Model and Scheduling Techniques for Power-aware Systems (2007)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh, Fadi Kurdahi

New embedded systems must be power-aware, not just low-power. That is, they must track their power sources and the changing power and performance constraints imposed by the environment. Moreover,...

Communication Speed Selection and Functional Partitioning for Low-Energy On-Chip Networked Multiprocessor ∗ Abstract (2007)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

High-speed serial network interfaces are becoming the primary way for modern embedded systems and systems-onchip to connect with each other and with peripheral devices. Modern communication...

Power-Aware Task Motion for Enhancing Dynamic Range of Embedded Systems with Renewable Energy Sources (2007)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

Abstract. New embedded systems are being built with new types of energy sources, including solar panels and energy scavenging devices, in order to maximize their utility when battery or A/C power is...

Power-aware Scheduling for Embedded Systems under Min/Max Power and Timing Constraints £ (2007)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh, Nazeeh Aranki, Nikzad “benny Toomarian

Power-aware systems are those that must make the best use of available power. They subsume traditional low-power systems in that they must not only minimize power when the budget is low, but also...

Supplementary material: "supplement.pdf" (2007)

Jinfeng Liu, Burkhard Rost

NOTE to the printer: Please maintain the italic typesetting for the first sentence of each paragraph instead of sub-headings. 1 More than 30 organisms have been entirely sequenced. Here, we applied a...

Communication Speed Selection and Functional Partitioning (2007)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

High-speed serial network interfaces are becoming the primary way for modern embedded systems and systems-onchip to connect with each other and with peripheral devices. Modern communication...

Distributed Embedded Systems for Low Power: A Case Study (2007)

Jinfeng Liu, Pai H. Chou

A multiple-processor system can potentially achieve higher energy savings than a single processor, because the reduced workload on each processor creates new opportunities for dynamic voltage scaling...

General Terms (2007)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

communication speed selection, communication/computation trade-offs, embedded multi-processor, lowpower design This paper presents a new technique for global energy optimization through coordinated...

Natively Unstructured Loops Differ from Other Loops (2007)

Avner Schlessinger, Jinfeng Liu, Burkhard Rost

Natively unstructured or disordered protein regions may increase the functional complexity of an organism; they are particularly abundant in eukaryotes and often evade structure determination. Many...

Natively Unstructured Loops Differ from Other Loops (2007)

Avner Schlessinger, Jinfeng Liu, Burkhard Rost

Natively unstructured or disordered protein regions may increase the functional complexity of an organism; they are particularly abundant in eukaryotes and often evade structure determination. Many...

Distinguishing Protein-Coding from Non-Coding RNAs through Support Vector Machines (2006)

Jinfeng Liu, Julian Gough, Burkhard Rost

RIKEN's FANTOM project has revealed many previously unknown coding sequences, as well as an unexpected degree of variation in transcripts resulting from alternative promoter usage and splicing. Ever...

System-lever optimization and validation for power-constrained embedded systems / (2006)

Liu, Jinfeng.

Thesis (Ph. D., Electrical and Computer Engineering)--University of California, Irvine, 2006.

B: Distinguishing protein-coding from noncoding RNAs through support vector machines. PLos Genetics 2006 (2006)

Jinfeng Liu, Julian Gough, Burkhard Rost

RIKEN’s FANTOM project has revealed many previously unknown coding sequences, as well as an unexpected degree of variation in transcripts resulting from alternative promoter usage and splicing....

Tapper: a lightweight scripting engine for highly constrained wireless sensor nodes (2006)

Qiang Xie, Jinfeng Liu, Pai H. Chou

Tapper is a lightweight scripting engine for highly constrained wireless sensor nodes. Many such nodes run on 8-bit microcontrollers (MCUs) with only a few kilobytes of on-chip memory, often with...

Solution structure of Archaeglobus fulgidis peptidyl-tRNA hydrolase (Pth2) provides evidence for an extensive conserved family of Pth2 enzymes in archea, bacteria, and eukaryotes (2005)

Powers, Robert, Mirkovic, Nebojsa, Goldsmith-Fischman, Sharon, Acton, Thomas B., Chiang, Yi-wen, Huang, Yuanpeng J., ...

The solution structure of protein AF2095 from the thermophilic archaea Archaeglobus fulgidis, a 123- residue (13.6-kDa) protein, has been determined by NMR methods. The structure of AF2095 is...

B#: a battery emulator and power profiling instrument (2005)

Chulsung Park, Jinfeng Liu, Pai H. Chou

This paper describes B # (B-sharp), a programmable power supply that emulates the behavior of a battery. It measures the current load, calls a battery simulation program to compute the voltage in...

Eco: an Ultra-Compact Low-Power Wireless Sensor Node for Real-Time Motion Monitoring (2005)

Chulsung Park, Jinfeng Liu, Pai H. Chou

Eco is an ultra-compact wireless sensor node. Only 648 mm 3 in volume and weighing under 1.6 grams, Eco was initially designed to monitor the spontaneous motion of preterm infants over 2.4GHz radio...

Solution structure of Archaeglobus fulgidis peptidyl-tRNA hydrolase (Pth2) provides evidence for an extensive conserved family of Pth2 enzymes in archea, bacteria, and eukaryotes (2005)

Powers, Robert, Mirkovic, Nebojsa, Goldsmith-Fischman, Sharon, Acton, Thomas B., Chiang, Yiwen, Huang, Yuanpeng J., ...

The solution structure of protein AF2095 from the thermophilic archaea Archaeglobus fulgidis, a 123-residue (13.6-kDa) protein, has been determined by NMR methods. The structure of AF2095 is...

1H, 13C, and 15N assignments for the Archaeglobus fulgidis protein AF2095 (2004)

Powers, Robert, Acton, Thomas B., Chiang, Yi-wen, Rajan, P. K., Cort, John R., Kennedy, Michael A., ...

Structural genomics is providing a means to determine the molecular and cellular function for the vast amount of proteins in the Human proteome that lack any explicit experimental information by...

Prediction-based genome annotation, domain assignment methods, and their applications in structural genomics (2004)

Liu, Jinfeng

The explosion of sequence information in post-genomic era is increasingly widening the gap between the number of protein sequences deposited in public databases and the experimental characterization...

Chop: parsing proteins into structural domains (2004)

Jinfeng Liu, Burkhard Rost

Sequence-based domain assignment is one of the most important and challenging problems in structural biology. We have developed a method, CHOP, that chops proteins into domain-like fragments. The...

The PredictProtein server (2004)

Rost, Burkhard, Yachdav, Guy, Liu, Jinfeng

PredictProtein (http://www.predictprotein.org) is an Internet service for sequence analysis and the prediction of protein structure and function. Users submit protein sequences or alignments;...

CHOP: parsing proteins into structural domains (2004)

Liu, Jinfeng, Rost, Burkhard

Sequence-based domain assignment is one of the most important and challenging problems in structural biology. We have developed a method, CHOP, that chops proteins into domain-like fragments. The...

Predicting transmembrane beta-barrels in proteomes (2004)

Bigelow, Henry R., Petrey, Donald S., Liu, Jinfeng, Przybylski, Dariusz, Rost, Burkhard

Very few methods address the problem of predicting beta‐barrel membrane proteins directly from sequence. One reason is that only very few high‐resolution structures for transmembrane...

Sequence-based prediction of protein domains (2004)

Liu, Jinfeng, Rost, Burkhard

Guessing the boundaries of structural domains has been an important and challenging problem in experimental and computational structural biology. Predictions were based on intuition, biochemical...

PEP: Predictions fo Entire Proteomes (2003)

Phil Carter, Jinfeng Liu, Burkhard Rost

PEP is a databaseo Predictioz fo Entire Proxfl mes. The database coS ains summarieso analyses o proSzfi sequencesfro a range o oSfi isms representing all three majo kingdon o life: eukary oary pro...

The PredictProtein Server (2003)

Burkhard Rost, Jinfeng Liu

PredictProfiWD (PP, http://cubic.bio c.coV mbia.edu/pp/) is an internet servicefo sequence analysis and the predictio o aspectso fproKxK structure and functioc Users submitpro tein sequenceo r...

NORSp: predictions of long regions without regular secondary structure (2003)

Jinfeng Liu, Burkhard Rost

Many structurallyflexil eregiEplay iay2 tant rolesi bies2 ies processes. It has been shown that extended loopy regi/G are very abundanti the protei n uniKP2fi and that they have been conserved...

The PredictProtein server (2003)

Rost, Burkhard, Liu, Jinfeng

PredictProtein (PP, http://cubic.bioc.columbia.edu/pp/) is an internet service for sequence analysis and the prediction of aspects of protein structure and function. Users submit protein sequence or...

NORSp: predictions of long regions without regular secondary structure (2003)

Liu, Jinfeng, Rost, Burkhard

Many structurally flexible regions play important roles in biological processes. It has been shown that extended loopy regions are very abundant in the protein universe and that they have been...

Solution NMR structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii (2003)

Aramini, James M., Huang, Yuanpeng J., Cort, John R., Goldsmith-Fischman, Sharon, Xiao, Rong, Shih, Liang-Yu, ...

We report NMR assignments and solution structure of the 71-residue 30S ribosomal protein S28E from the archaean Pyrococcus horikoshii, target JR19 of the Northeast Structural Genomics Consortium. The...

PEP: Predictions for Entire Proteomes (2003)

Carter, Phil, Liu, Jinfeng, Rost, Burkhard

PEP is a database of Predictions for Entire Proteomes. The database contains summaries of analyses of protein sequences from a range of organisms representing all three major kingdoms of life:...

Communication speed selection for embedded systems with networked voltage-scalable processors (2002)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

High-speed serial network interfaces are gaining wide use in connecting multiple processors and peripherals in modern embedded systems, thanks to their size advantage and power efficiency. Many such...

IMPACCT: Methodology and tools for power aware embedded systems", Design Automation for Embedded Systems (2002)

Pai H. Chou, Jinfeng Liu, Dexin Li, Nader Bagherzadeh

Power-aware systems are those that must exploit a wide range of power/performance tradeoffs in order to adapt to the power availability and application requirements. They require the integration of...

Communication speed selection for embedded systems with networked voltage-scalable processors (2002)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

High-speed serial network interfaces are gaining wide use in connecting multiple processors and peripherals in modern embedded systems, thanks to their size advantage and power efficiency. Many such...

Communication speed selection for embedded systems with networked voltage-scalable processors (2002)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

High-speed serial network interfaces are gaining wide use in con-necting multiple processors and peripherals in modem embedded systems, thanks to their size advantage and power efficiency. Many such...

IMPACCT: Methodology and tools for power aware embedded systems", Design Automation for Embedded Systems (2002)

Pai H. Chou, Jinfeng Liu, Dexin Li, Nader Bagherzadeh

Power-aware systems are those that must exploit a wide range of power/performance tradeoffs in order to adapt to the power availability and application requirements. They require the integration of...

Target space for structural genomics revisited (2002)

Liu, Jinfeng, Rost, Burkhard

Motivation: Structural genomics eventually aims at determining structures for all proteins. However, in the beginning experimentalists are likely to focus on globular proteins to achieve a rapid...

Power-Aware Scheduling under Timing Constraints for Mission-Critical Embedded Systems (2001)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh, Fadi Kurdahi

1 This research was sponsored by DARPA under contract F33615-00-1-1719 Power-aware systems are those that must make the best use of available power. They subsume traditional low-power systems in that...

Power-aware task motion: Dynamic range enhancement for power-aware embedded systems (2001)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh

1 This research was sponsored by DARPA under contract F33615-00-1-1719 New embedded systems are being built with new types of energy sources, including solar panels and energy scavenging devices, in...

Power-Aware Scheduling under Timing Constraints for Mission-Critical Embedded Systems (2001)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh, Fadi Kurdahi

Power-aware systems are those that must make the best use of available power. They subsume traditional low-power systems in that they must not only minimize power when the budget is low, but also...

Power-Aware Scheduling under Timing Constraints for Mission-Critical Embedded Systems (2001)

Jinfeng Liu, Pai H. Chou, Nader Bagherzadeh, Fadi Kurdahi

Power-aware systems are those that must make the best use of available power. They subsume traditional low-power systems in that they must not only minimize power when the budget is low, but also...

Comparing function and structure between entire proteomes (2001)

Liu, Jinfeng, Rost, Burkhard

More than 30 organisms have been sequenced entirely. Here, we applied a variety of simple bioinformatics tools to analyze 29 proteomes for representatives from all three kingdoms: eukaryotes,...

PEP: Predictions for Entire Proteomes

Carter, Phil, Liu, Jinfeng, Rost, Burkhard

PEP is a database of Predictions for Entire Proteomes. The database contains summaries of analyses of protein sequences from a range of organisms representing all three major kingdoms of life:...

The PredictProtein server

Rost, Burkhard, Liu, Jinfeng

PredictProtein (PP, http://cubic.bioc.columbia.edu/pp/) is an internet service for sequence analysis and the prediction of aspects of protein structure and function. Users submit protein sequence or...

NORSp: predictions of long regions without regular secondary structure

Liu, Jinfeng, Rost, Burkhard

Many structurally flexible regions play important roles in biological processes. It has been shown that extended loopy regions are very abundant in the protein universe and that they have been...

The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity

Galagan, James E., Nusbaum, Chad, Roy, Alice, Endrizzi, Matthew G., Macdonald, Pendexter, FitzHugh, Will, ...

Methanogenesis, the biological production of methane, plays a pivotal role in the global carbon cycle and contributes significantly to global warming. The majority of methane in nature is derived...

Predicting transmembrane beta-barrels in proteomes

Bigelow, Henry R., Petrey, Donald S., Liu, Jinfeng, Przybylski, Dariusz, Rost, Burkhard

Very few methods address the problem of predicting beta-barrel membrane proteins directly from sequence. One reason is that only very few high-resolution structures for transmembrane beta-barrel...

The PredictProtein server

Rost, Burkhard, Yachdav, Guy, Liu, Jinfeng

PredictProtein (http://www.predictprotein.org) is an Internet service for sequence analysis and the prediction of protein structure and function. Users submit protein sequences or alignments;...

CHOP: parsing proteins into structural domains

Liu, Jinfeng, Rost, Burkhard

Sequence-based domain assignment is one of the most important and challenging problems in structural biology. We have developed a method, CHOP, that chops proteins into domain-like fragments. The...

Sequence-based prediction of protein domains

Liu, Jinfeng, Rost, Burkhard

Guessing the boundaries of structural domains has been an important and challenging problem in experimental and computational structural biology. Predictions were based on intuition, biochemical...

Distinguishing Protein-Coding from Non-Coding RNAs through Support Vector Machines

Liu, Jinfeng, Gough, Julian, Rost, Burkhard

RIKEN's FANTOM project has revealed many previously unknown coding sequences, as well as an unexpected degree of variation in transcripts resulting from alternative promoter usage and splicing. Ever...

PEP: Predictions for Entire Proteomes

Carter, Phil, Liu, Jinfeng, Rost, Burkhard

PEP is a database of Predictions for Entire Proteomes. The database contains summaries of analyses of protein sequences from a range of organisms representing all three major kingdoms of life:...

The PredictProtein server

Rost, Burkhard, Liu, Jinfeng

PredictProtein (PP, http://cubic.bioc.columbia.edu/pp/) is an internet service for sequence analysis and the prediction of aspects of protein structure and function. Users submit protein sequence or...

NORSp: predictions of long regions without regular secondary structure

Liu, Jinfeng, Rost, Burkhard

Many structurally flexible regions play important roles in biological processes. It has been shown that extended loopy regions are very abundant in the protein universe and that they have been...

The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity

Galagan, James E., Nusbaum, Chad, Roy, Alice, Endrizzi, Matthew G., Macdonald, Pendexter, FitzHugh, Will, ...

Methanogenesis, the biological production of methane, plays a pivotal role in the global carbon cycle and contributes significantly to global warming. The majority of methane in nature is derived...

Predicting transmembrane beta-barrels in proteomes

Bigelow, Henry R., Petrey, Donald S., Liu, Jinfeng, Przybylski, Dariusz, Rost, Burkhard

Very few methods address the problem of predicting beta-barrel membrane proteins directly from sequence. One reason is that only very few high-resolution structures for transmembrane beta-barrel...

The PredictProtein server

Rost, Burkhard, Yachdav, Guy, Liu, Jinfeng

PredictProtein (http://www.predictprotein.org) is an Internet service for sequence analysis and the prediction of protein structure and function. Users submit protein sequences or alignments;...

CHOP: parsing proteins into structural domains

Liu, Jinfeng, Rost, Burkhard

Sequence-based domain assignment is one of the most important and challenging problems in structural biology. We have developed a method, CHOP, that chops proteins into domain-like fragments. The...

Sequence-based prediction of protein domains

Liu, Jinfeng, Rost, Burkhard

Guessing the boundaries of structural domains has been an important and challenging problem in experimental and computational structural biology. Predictions were based on intuition, biochemical...

Distinguishing Protein-Coding from Non-Coding RNAs through Support Vector Machines

Liu, Jinfeng, Gough, Julian, Rost, Burkhard

RIKEN's FANTOM project has revealed many previously unknown coding sequences, as well as an unexpected degree of variation in transcripts resulting from alternative promoter usage and splicing. Ever...

Natively Unstructured Loops Differ from Other Loops

Schlessinger, Avner, Liu, Jinfeng, Rost, Burkhard

Natively unstructured or disordered protein regions may increase the functional complexity of an organism; they are particularly abundant in eukaryotes and often evade structure determination. Many...

Solution structure of Archaeglobus fulgidis peptidyl-tRNA hydrolase (Pth2) provides evidence for an extensive conserved family of Pth2 enzymes in archea, bacteria, and eukaryotes

Powers, Robert, Mirkovic, Nebojsa, Goldsmith-Fischman, Sharon, Acton, Thomas B., Chiang, Yiwen, Huang, Yuanpeng J., ...

The solution structure of protein AF2095 from the thermophilic archaea Archaeglobus fulgidis, a 123-residue (13.6-kDa) protein, has been determined by NMR methods. The structure of AF2095 is...

Solution NMR structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii

Aramini, James M., Huang, Yuanpeng J., Cort, John R., Goldsmith-Fischman, Sharon, Xiao, Rong, Shih, Liang-Yu, ...

We report NMR assignments and solution structure of the 71-residue 30S ribosomal protein S28E from the archaean Pyrococcus horikoshii, target JR19 of the Northeast Structural Genomics Consortium. The...

Comparing function and structure between entire proteomes

Liu, Jinfeng, Rost, Burkhard

More than 30 organisms have been sequenced entirely. Here, we applied a variety of simple bioinformatics tools to analyze 29 proteomes for representatives from all three kingdoms: eukaryotes,...

Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective

Liu, Jinfeng, Zhang, Yan, Lei, Xingye, Zhang, Zemin

A large-scale survey using single nucleotide polymorphism data from dbSNP provides insights into the evolutionary selection constraints on human proteins of different structural and functional...

Structural genomics is the largest contributor of novel structural leverage

Nair, Rajesh, Liu, Jinfeng, Soong, Ta-Tsen, Acton, Thomas B., Everett, John K., Kouranov, Andrei, ...

The Protein Structural Initiative (PSI) at the US National Institutes of Health (NIH) is funding four large-scale centers for structural genomics (SG). These centers systematically target many large...

Association of C-Terminal Ubiquitin Hydrolase BRCA1-Associated Protein 1 with Cell Cycle Regulator Host Cell Factor 1▿

Misaghi, Shahram, Ottosen, Søren, Izrael-Tomasevic, Anita, Arnott, David, Lamkanfi, Mohamed, Lee, James, ...

Protein ubiquitination provides an efficient and reversible mechanism to regulate cell cycle progression and checkpoint control. Numerous regulatory proteins direct the addition of ubiquitin to...