Abstract — The search for the association between complex diseases and single nucleotide polymorphisms (SNPs) or haplotypes has recently received great attention. For these studies, it is essential...
Family trio phasing and missing data recovery (2009)
Dumitru Brinza, Jingwu He, Weidong Mao, Alexander Zelikovsky
Abstract: Although there exist many phasing methods for unrelated adults or pedigrees, phasing and missing data recovery for data representing family trios is lagging behind. This paper is an attempt...
1 Optimization Methods for Genotype Data Analysis in Epidemiological Studies (2008)
Dumitru Brinza, Jingwu He, Er Zelikovsky
Recent improvement in accessibility of high-throughput DNA sequencing brought a great deal of attention to disease association and susceptibility studies. Successful genome-wide searches for...
Prediction Methods for Inherited Disease (2008)
Weidong Mao, Jingwu He, Kelly Westbrooks
Recent improvements in the accessibility of high-throughput genotyping have brought a great deal of attention to disease association studies[6]. It is believed that more accurate disease association...
18 OPTIMIZATION METHODS FOR GENOTYPE DATA ANALYSIS IN EPIDEMIOLOGICAL STUDIES (2008)
Dumitru Brinza, Jingwu He, Er Zelikovsky
Recent improvement in accessibility of high throughput DNA sequencing brought a great deal of attention to disease association and susceptibility studies. Successful genome-wide searches for...
Phasing and Missing Data Recovery in Family (2008)
Dumitru Brinza, Jingwu He, Weidong Mao, Er Zelikovsky
Abstract. Although there exist many phasing methods for unrelated adults or pedigrees, phasing and missing data recovery for data representing family trios is lagging behind. This paper is an attempt...
Haplotype Tagging using Support Vector Machines (2008)
Jingwu He, Jun Zhang, Gulsah Altun, Er Zelikovsky, Yanqing Zhang
Abstract — Constructing a complete human haplotype map can help in associating complex diseases with SNPs (single nucleotide polymorphisms). Unfortunately, the number of SNPs is very large and it...
Family Trio Phasing and Missing Data Recovery ∗ (2008)
Dumitru Brinza, Jingwu He, Weidong Mao, Alexander Zelikovsky
Abstract: Although there exist many phasing methods for unrelated adults or pedigrees, phasing and missing data recovery for data representing family trios is lagging behind. This paper is an attempt...
Algorithms for computational genetics epidemiology (2006)
Thesis (Ph. D.)--Georgia State University, 2006.
Combinatorial Search Methods for Multi-SNP Disease Association (2006)
Dumitru Brinza, Jingwu He, Er Zelikovsky
Abstract — Recent improvements in the accessibility of highthroughput genotyping have brought a deal of attention to genome-wide association studies for common complex diseases. Although, such...
Jingwu He, Er Zelikovsky, Martin Bishop
Summary: The search for the association between complex diseases and single nucleotide polymorphisms (SNPs) or haplotypes has recently received great attention. For these studies, it is essential to...
Tag SNP Selection Based on Multivariate Linear Regression (2006)
Abstract. The search for the association between complex diseases and single nucleotide polymorphisms (SNPs) or haplotypes has been recently received great attention. For these studies, it is...
ALGORITHMS FOR COMPUTATIONAL GENETIC EPIDEMIOLOGY by (2006)
Jingwu He, Under Direction, Alex Zelikovsky, Jingwu He, Jingwu He, Jingwu He
The most intriguing problems in genetics epidemiology are to predict genetic disease susceptibility and to associate single nucleotide polymorphisms (SNPs) with diseases. In such these studies, it is...
He, Jingwu, Zelikovsky, Alexander
Summary: The search for the association between complex diseases and single nucleotide polymorphisms (SNPs) or haplotypes has recently received great attention. For these studies, it is essential to...
Family trio phasing and missing data recovery (2005)
Dumitru Brinza, Jingwu He, Weidong Mao, Alexander Zelikovsky
Although there exist many phasing methods for unrelated adults or pedigrees, phasing and missing data recovery for data representing family trios is lagging behind. This paper is an attempt to fill...
Family trio phasing and missing data recovery (2005)
Dumitru Brinza, Jingwu He, Weidong Mao, Alexander Zelikovsky
Although there exist many phasing methods for unrelated adults or pedigrees, phasing and missing data recovery for data representing family trios is lagging behind. This paper is an attempt to fill...
Downloading and Installing (2005)
Welcome. Thank you very much for using feasibleTrioPhasing program. This document describes how to use feasibleTrioPhasing, a program to feasibly phasing trio data. The purpose of this program is to...
MLRtagging: Genotype Tagging Based on SNP Multivariate Linear Regression (2005)
MLRtagging software package implements a novel genotype tagging method based on multivariate linear regression (MLR) analysis. This software can be used for tag selection and genotype prediction. The...
A Combinatorial Method for Predicting Genetic Susceptibility to Complex Diseases (2005)
Weidong Mao, Jingwu He, Dumitru Brinza, Alex Zelikovsky
Abstract — Recent improvements in the accessibility of highthroughput genotyping have brought a great deal of attention to disease association and susceptibility studies. This paper explores...
Predicting and Phasing for Case/Control Family Trio Data. Submitted to ISMB2005. (2005)
Welcome. Thank you very much for using randomTrioPhasing program. This document describes how to use randomTrioPhasing, a program to randomly phasing trio data with no recombination. The purpose of...
Linear Reduction Method for Predictive and Informative Tag SNP (2005)
Jingwu He, Kelly Westbrooks, Er Zelikovsky
Constructing a complete human haplotype map is helpful when associating complex dis-eases with their related SNPs. Unfortunately, the number of SNPs is very large and it is costly to sequence many...
Linear Reduction for Haplotype Inference (2004)
Abstract. Haplotype inference problem asks for a set of haplotypes explaining a given set of genotypes. Popular software tools for haplotype inference (e.g., PHASE, HAPLOTYPER) as well as new...
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