Joël Vandekerckhove

The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain (2009)

Tun, Moe, Remue, Eline, De Ganck, Ariane, Boucherie, Ciska, Vanloo, Berlinda, ...

Zonula occludens proteins (ZO) are postsynaptic density protein-95 discs large-zonula occludens (PDZ) domain-containing proteins that play a fundamental role in the assembly of tight junctions and...

A review of COFRADIC techniques targeting protein N-terminal acetylation (2009)

Van Damme, Petra, Van Damme, Jozef, Demol, Hans, Staes, An, Vandekerckhove, Joël, Gevaert, Kris

Abstract Acetylation of nascent protein N α -termini is a common modification among archae and eukaryotes and can influence the structure and function of target proteins. This modification has been...

Phenotypes induced by NM causing α-skeletal muscle actin mutants in fibroblasts, Sol 8 myoblasts and myotubes (2009)

Vandamme, Drieke, Lambert, Ellen, Waterschoot, Davy, Tondeleir, Davina, Vandekerckhove, Joël, Machesky, Laura M, ...

Abstract Background Nemaline myopathy is a neuromuscular disorder characterized by the presence of nemaline bodies in patient muscles. 20% of the cases are associated with α-skeletal muscle actin...

The actin-capping protein CapG localizes to microtubule-dependent organelles during the cell cycle (2009)

Hubert, Thomas, Van Impe, Katrien, Vandekerckhove, Joël, Gettemans, Jan

Extensive cross-talk between the actin and the microtubule cytoskeletons has been reported. Especially In mitosis, processes dependent on actin- and microtubule-based structures alternate and...

Analysis of Protein Processing by N-terminal Proteomics Reveals Novel Species-specific Substrate Determinants of Granzyme B Orthologs (2009)

Van Damme, Petra, Maurer-Stroh, Sebastian, Plasman, Kim, Van Durme, Joost, Colaert, Niklaas, Timmerman, Evy, ...

Using a targeted peptide-centric proteomics approach, we performed in vitro protease substrate profiling of the apoptotic serine protease granzyme B resulting in the delineation of more than 800...

The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes (2009)

Lalioti, Vasiliki, Muruais, Gemma, Dinarina, Ana, Van Damme, Jozef, Vandekerckhove, Joël, Sandoval, Ignacio V.

Here, we report that Cdk5 activation is stimulated by insulin and plays a key role in the regulation of GLUT4-mediated glucose uptake in 3T3-L1 adipocytes. Insulin activation of Cdk5 requires PI3K...

alpha-Skeletal Muscle Actin Mutants Causing Different Congenital Myopathies Induce Similar Cytoskeletal Defects in Cell Line Cultures (2009)

Vandamme, Drieke, Rommelaere, Heidi, Lambert, Ellen, Waterschoot, Davy, Vandekerckhove, Joël, Constantin, Bruno, ...

Central core disease (CCD), congenital fibre type disproportion (CFTD), and nemaline myopathy (NM) are earlyonset clinically heterogeneous congenital myopathies, characterized by generalized Muscle...

The Mouse Thymosin Beta15 Gene Family Displays Unique Complexity and Encodes A Functional Thymosin Repeat (2009)

Dhaese, Stien, Vandepoele, Klaas, Waterschoot, Davy, Vanloo, Berlinda, Vandekerckhove, Joël, Ampe, Christophe, ...

We showed earlier that human beta -thymosin 15 (Th15) is up-regulated in prostate cancer, confirming Studies from others that propagated Tb15 as a prostate cancer biomarker. In this first report on...

The Interaction of Proline-Rich Ligands with Profilin Probed with an Enzyme-Linked Immunosorbent Assay (2009)

Veniere, Sylvie, Ampe, Christophe, Vandekerckhove, Joël, Lambrechts, Anja

To to detect interactions of different proline-rich ligands with profilins, the authors developed a simple analytical antibody-based screening method. profilin I or profilin IIa was coated in...

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans (2009)

Arnesen, Thomas, Van Damme, Petra, Polevoda, Bogdan, Helsens, Kenny, Evjenth, Rune, Colaert, Niklaas, ...

N alpha-terminal acetylation is one of the most common protein modifications in eukaryotes. The COmbined FRActional DIagonal Chromatography (COFRADIC) proteomics technology that can be specifically...

Structure of granzyme C reveals an unusual mechanism of protease autoinhibition (2009)

Kaiserman, Dion, Buckle, Ashley M, Van Damme, Petra, Irving, James A., Law, Ruby H. P., Matthews, Antony Y., ...

Proteases act in important homeostatic pathways and are tightly regulated. Here, we report an unusual structural mechanism of regulation observed by the 2.5-angstrom X-ray crystal structure of the...

Down-regulation of myopodin expression reduces invasion and motility of PC-3 prostate cancer cells (2009)

De Ganck, Ariane, DE CORTE, VEERLE, Bruyneel, Erik, Bracke, Marc, Vandekerckhove, Joël, Gettemans, Jan

Enhanced motility of cancer cells by remodelling of the actin cytoskeleton is crucial in the process of cancer cell invasion and metastasis. Although several studies propose a tumor suppressor role...

alpha-Skeletal muscle actin nemaline myopathy mutants cause cell death in cultured muscle cells. (2009)

Vandamme, Drieke, Lambert, Ellen, Waterschoot, Davy, Cognard, C., Vandekerckhove, Joël, Ampe, Christophe, ...

Nemaline myopathy is a neuromuscular disorder, characterized by muscle weakness and hypotonia and is, in 20% of the cases, caused by mutations in the gene encoding alpha-skeletal muscle actin, ACTA1....

Impaired neural crest migration contributes to midgestation lethality of beta-actin knock-out mouse (2009)

Tondeleir, Davina, Mueller, Matthias, Jonckheere, Veronique, Waterschoot, Davy, Bakkali, Karima, Vandekerckhove, Joël, ...

A review of COFRADIC techniques targeting protein N-terminal acetylation (2009)

Van Damme, Petra, Van Damme, Jozef, Demol, Hans, Staes, An, Vandekerckhove, Joël, Gevaert, Kris

Acetylation of nascent protein Nalpha-termini is a common modification among archae and eukaryotes and can influence the structure and function of target proteins. This modification has been studied...

Approaching clinical proteomics: current state and future fields of application in fluid proteomics (2009)

Apweiler, Rolf, Aslanidis, Charalampos, Deufel, Thomas, Gerstner, Andreas, Hansen, Jens, Hochstrasser, Dennis, ...

The field of clinical proteomics offers opportunities to identify new disease biomarkers in body fluids, cells and tissues. These biomarkers can be used in clinical applications for diagnosis,...

Exo70-Mediated Recruitment of Nucleoporin Nup62 at the Leading Edge of Migrating Cells is Required for Cell Migration (2009)

Hubert, Thomas, Vandekerckhove, Joël, Gettemans, Jan

Nucleoporin Nup62 localizes at the central channel of the nuclear pore complex and is essential for nucleocytoplasmic transport. Through its FG-repeat domain, Nup62 regulates nuclear pore...

Getting a grip on proteomics data - Proteomics Data Collection (ProDaC) (2009)

Eisenacher, Martin, Martens, Lennart, Kohl, Michael, Barsnes, Harald, Helsens, Kenny, Häkkinen, Jari, ...

In proteomics, rapid developments in instrumentation led to the acquisition of increasingly large data sets. Correspondingly, ProDaC was founded in 2006 as a Coordination Action project within the...

Phenotypes induced by NM causing alpha-skeletal muscle actin mutants in fibroblasts, Sol 8 myoblasts and myotubes. (2009)

Vandamme, Drieke, Lambert, Ellen, Waterschoot, Davy, Tondeleir, Davina, Machesky, Laura M, Vandekerckhove, Joël, ...

Background Nemaline myopathy is a neuromuscular disorder characterized by the presence of nemaline bodies in patient muscles. 20% of the cases are associated with α-skeletal muscle actin mutations....

Actin isoform expression patterns during mammalian development and in pathology: Insights from mouse models. (2009)

Tondeleir, Davina, Vandamme, Drieke, Vandekerckhove, Joël, Ampe, Christophe, Lambrechts, Anja

The dynamic actin cytoskeleton, consisting of six actin isoforms in mammals and a variety of actin binding proteins is essential for all developmental processes and for the viability of the adult...

Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering. (2009)

Leyman, S., Sidani, M., Ritsma, L., Waterschoot, Davy, Eddy, R., Dewitte, D., ...

Cofilin is a key player in actin dynamics during cell migration. Its activity is regulated by (de)phosphorylation, pH, and binding to phosphatidylinositol-4,5-bisphosphate [PI(4,5)P(2)]. Here, we...

Improved visualization of protein consensus sequences by iceLogo (2009)

Colaert, Niklaas, Helsens, Kenny, Martens, Lennart, Vandekerckhove, Joël, Gevaert, Kris

Characterization of a Listeria monocytogenes protein interfering with Rab5a (2008)

ALVAREZ-DOMINGUEZ, C, MADRAZO-TOCA, F, FERNANDEZ-PRIETO, L, Vandekerckhove, Joël, PAREJA, E, TOBES, R, ...

An influenza A vaccine based on tetrameric ectodomain of matrix protein 2 (2008)

De Filette, Marina, Martens, Wouter, Roose, Kenny, Deroo, Tom, Vervalle, Frederik, Bentahir, Mostafa, ...

Mechanistic insight into taxol-induced cell death (2008)

Impens, Francis, Van Damme, Petra, Demol, Hans, Van Damme, Jozef, Vandekerckhove, Joël, Gevaert, Kris

Evaluation of encoded layer-by-layer coated microparticles as protease sensors (2008)

Stubbe, Barbara, Gevaert, Kris, Derveaux, Stefaan, Braeckmans, Kevin, De Geest, Bruno, Goethals, Marc, ...

The proteome of the human neuroblastoma cell line SH-SY5Y: An enlarged proteome (2008)

GILANY, K, VAN ELZEN, R, MOUS, K, COEN, E, VAN DONGEN, W, VANDAMME, S, ...

Multiple isoforms of the tumor suppressor myopodin are simultaneously transcribed in cancer cells (2008)

De Ganck, Ariane, De Corte, Veerle, Staes, An, Gevaert, Kris, Vandekerckhove, Joël, Gettemans, Jan

Listeria comet tails: the actin-based motility machinery at work (2008)

Lambrechts, Anja, Gevaert, Kris, COSSART, P, Vandekerckhove, Joël, Van Troys, Marleen

Improved recovery of proteome-informative, protein N-terminal peptides by combined fractional diagonal chromatography (COFRADIC) (2008)

Staes, An, Van Damme, Petra, Helsens, Kenny, Demol, Hans, Vandekerckhove, Joël, Gevaert, Kris

Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death (2008)

GAUSDAL, G, GJERTSEN, BT, MCCORMACK, E, DAMME, P, HOVLAND, R, KRAKSTAD, C, ...

Human Proteinpedia enables sharing of human protein data (2008)

MATHIVANAN, S, AHMED, M, AHN, NG, ALEXANDRE, H, AMANCHY, R, ANDREWS, PC, ...

The actin propulsive machinery: The proteome of Listeria monocytogenes tails (2008)

Van Troys, Marleen, Lambrechts, Anja, DAVID, VERA, Demol, Hans, Puype, Magda, PIZARRO-CERDA, J, ...

A new role for nuclear transport factor 2 and Ran: Nuclear import of CapG (2008)

Van Impe, Katrien, Hubert, Thomas, De Corte, Veerle, Vanloo, Berlinda, Boucherie, Ciska, Vandekerckhove, Joël, ...

Caspase-14 is a crucial protease in proper stratum corneum formation (2008)

HOSTE, E, DENECKER, G, Van Damme, Petra, HACHEM, J, GILBERT, B, Ovaere, Petra, ...

Unravelling the RIP4 signaling pathway to NF-kappa B (2008)

DE GROOTE, P, LIPPENS, S, GILBERT, B, Gevaert, Kris, Vandekerckhove, Joël, VANDENABEELE, P, ...

Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes (2008)

Lamkanfi, Mohamed, KANNEGANTI, TD, Van Damme, Petra, Vanden Berghe, Tom, Vanoverberghe, Isabel, Vandekerckhove, Joël, ...

Protein processing characterized by a gel-free proteomics approach (2008)

Van Damme, Petra, Impens, Francis, Vandekerckhove, Joël, Gevaert, Kris

We describe a method for the specific isolation of representative N-terminal peptides of proteins and their proteolytic fragments. Their isolation is based on a gel-free, peptidecentric proteomics...

The F-actin filament capping protein CapG is a bona fide nucleolar protein (2008)

Hubert, Thomas, Van Impe, Katrien, Vandekerckhove, Joël, Gettemans, Jan

Actin works in concert with myosin I to regulate the transcription of ribosomal genes in the nucleolus. Recently, nucleolar actin has been shown to be active in its polymeric form raising the...

The Tandem PDZ Protein Syntenin Interacts with the Aminoacyl tRNA Synthetase Complex in a Lysyl-tRNA Synthetase-Dependent Manner (2008)

Meerschaert, Kris, Remue, Eline, De Ganck, Ariane, Staes, An, Boucherie, Ciska, Gevaert, Kris, ...

Syntenin-1 is a tandem PDZ protein that binds a diverse array of signaling molecules that are often associated with cell adhesion and intracellular trafficking. With the use of a MS-based functional...

IMMUNOMODULATION OF CANCER CELL MIGRATION AND INVASION USING RECOMBINANT CAMELID NANOBODIES AGAINST CYTOSKELETAL PROTEINS (2008)

Delanote, Veerle, Van Den Abbeele, Anske, De Clercq, Sarah, De Ganck, Ariane, Van Impe, Katrien, De Corte, Veerle, ...

Stable isotopic labeling in proteomics (2008)

Gevaert, Kris, Impens, Francis, Ghesquière, Bart, Van Damme, Petra, Lambrechts, Anja, Vandekerckhove, Joël

Labeling of proteins and peptides with stable heavy isotopes (deuterium, carbon-13, nitrogen-15, and oxygen-18) is widely used in quantitative proteomics. These are either incorporated metabolically...

Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex (2008)

Verstappen, Griet, Van Grunsven, Leo A., Michiels, Christine, Van De Putte, Tom, Souopgui, Jacob, Van Damme, Jozef, ...

Mutations in ZFHX1B cause Mowat–Wilson syndrome (MWS) but the precise mechanisms underlying the aberrant functions of mutant ZFHX1B proteins (also named Smad-interacting protein-1, SIP1) in...

Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex (2008)

Verstappen, Griet, Van Grunsven, Leo A., Michiels, Christine, Van De Putte, Tom, Souopgui, Jacob, Van Damme, Jozef, ...

Mutations in ZFHX1B cause Mowat-Wilson syndrome (MWS) but the precise mechanisms underlying the aberrant functions of mutant ZFHX1B proteins (also named Smad-interacting protein-1, SIP1) in patients...

Proteome-wide identification of HtrA2/Omi substrates (2007)

Vande Walle, Lieselotte, Van Damme, Petra, Lamkanfi, Mohamed, Saelens, Xavier, Vandekerckhove, Joël, Gevaert, Kris, ...

On the origin and evolution of vertebrate and viral profilins (2007)

POLET, D, Lambrechts, Anja, Vandepoele, Klaas, Vandekerckhove, Joël, Ampe, Christophe

Caspase-14 protects against epidermal UVB photo-damage and water loss. (2007)

Denecker, Geertrui, Hoste, Esther, Gilbert, Barbara, Hochepied, Tino, Ovaere, Petra, Lippens, Saskia, ...

Combination of COFRADIC and high temperature - extended column length conventional liquid chromatography: A very efficient way to tackle complex protein samples, such as serum (2007)

SANDRA, K, VERLEYSEN, K, Labeur, Christine, VANNESTE, L, D'HONDT, F, THOMAS, G, ...

MascotDatfile: An open-source library to fully parse and analyse MASCOT MS/MS search results (2007)

Helsens, Kenny, MARTENS, L, Vandekerckhove, Joël, Gevaert, Kris

The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation (2007)

STUCKE, VM, Timmerman, Evy, Vandekerckhove, Joël, Gevaert, Kris, HALL, A

The tandem PDZ domains of syntenin promote cell invasion (2007)

Meerschaert, Kris, Bruyneel, Erik, De Wever, Olivier, Vanloo, Berlinda, Boucherie, Ciska, Bracke, Marc, ...

The C-terminus of CIS defines its interaction pattern (2007)

Lavens, Delphine, Ulrichts, Peter, Catteeuw, Dominiek, Gevaert, Kris, Vandekerckhove, Joël, Peelman, Frank, ...

Methylglyoxal suppresses TNF-alpha-induced NF-kappa B activation by inhibiting NF-kappa B DNA-binding (2007)

Laga, Mathias, Cottyn, Anneleen, Van Herreweghe, Franky, Vanden Berghe, Wim, Haegeman, Guy, Van Oostveldt, Patric, ...

Structural and Functional Implications of the PXWK-motif in HeadPiece Domains (2007)

Bourry, David, VERMEULEN, W, Van Troys, Marleen, Vandekerckhove, Joël, Ampe, Christophe, Martins, José

Structural and Functional Implicationof the PXWK-motif in HeadPiece Domains (2007)

Bourry, David, VERMEULEN, W, Van Troys, Marleen, Vandekerckhove, Joël, Ampe, Christophe, Martins, José

Downregulation of gelsolin family proteins counteracts cancer cell invasion in vitro (2007)

De Corte, Veerle, Van Impe, Katrien, Bruyneel, Erik, BOTTCHERIE, C, Bracke, Marc, ...

Large-scale identification of N-terminal peptides in the halophilic archaea Halobacterium salinarum and Natronomonas pharaonis (2007)

AIVALIOTIS, M, Gevaert, Kris, FALB, M, TEBBE, A, KONSTANTINIDIS, K, BISLE, B, ...

Assessing a novel microfluidic interface for shotgun proteome analyses (2007)

Staes, An, Timmerman, Evy, VAN DAMME, I, Helsens, Kenny, Vandekerckhove, Joël, VOLLMER, M, ...

A la carte proteomics with an emphasis on gel-free techniques (2007)

Gevaert, Kris, Van Damme, Petra, Ghesquière, Bart, Impens, Francis, MARTENS, L, Helsens, Kenny, ...

Implementation and application of a versatile clustering tool for tandem mass spectrometry data (2007)

FLIKKA, K, Meukens, Jeroen, HELSENSI, K, Vandekerckhove, Joël, EIDHAMMER, I, Gevaert, Kris, ...

A new approach for mapping sialylated N-glycosites in serum proteomes (2007)

Ghesquière, Bart, Buyl, Lien, Demol, Hans, Van Damme, Jozef, Staes, An, Timmerman, Evy, ...

Applications of diagonal chromatography for proteome-wide characterization of protein modifications and activity-based analyses (2007)

Gevaert, Kris, Impens, Francis, DAMME, P, Ghesquière, Bart, Hanoulle, Xavier, Vandekerckhove, Joël

Functional and profiling studies prove that prostate cancer upregulated neuroblastoma thymosin beta is the true human homologue of rat thymosin beta 15 (2007)

Dhaese, Stien, Jonckheere, Veronique, Goethals, Marc, WALTREGNY, D, Vandekerckhove, Joël, Ampe, Christophe, ...

Mammalian protein-protein interaction trap (MAPPIT) analysis of STAT5, CIS, and SOCS2 interactions with the growth hormone receptor (2007)

Uyttendaele, Isabel, Lemmens, Irma, Verhee, Annick, De Smet, Anne-Sophie, Vandekerckhove, Joël, Lavens, Delphine, ...

Tumour necrosis factor induces phosphorylation primarily of the nitric-oxide-responsive form of glyoxalase I (2007)

De Hemptinne, Virginie, Rondas, Dieter, Vandekerckhove, Joël, Vancompernolle, Katia

The minimum information about a proteomics experiment (MIAPE) (2007)

TAYLOR, CF, PATON, NW, LILLEY, KS, BINZ, PA, JULIAN, RK, JONES, AR, ...

Paper of the year 2006: Award to Pamela Hamill (2007)

Vandekerckhove, Joël

Caspase-14 protects against epidermal UVB photo-damage and water loss (2007)

Denecker, Geertrui, Hoste, Esther, Gilbert, Barbara, Hochepied, Tino, Ovaere, Petra, Lippens, Saskia, ...

Caspase-14 protects against epidermal UVB photodamage and water loss (2007)

Denecker, Geertrui, Hoste, Esther, Gilbert, Barbara, Hochepied, Tino, Ovaere, Petra, Lippens, Saskia, ...

Caspase-14 protects against epidermal UVB photo-damage and water loss (2007)

Denecker, Geertrui, Hoste, Esther, Gilbert, Barbara, Hochepied, Tino, Ovaere, Petra, Lippens, Saskia, ...

Identification and characterization of filaggrin as a caspase-14 substrate (2007)

Hoste, Esther, Denecker, Geertrui, Van Damme, Petra, PRESLAND, RB, Vandekerckhove, Joël, Gevaert, Kris, ...

Cell_motility: a cross-platform, open source application for the study of cell motion paths (2006)

Martens, Lennart, Monsieur, Geert, Ampe, Christophe, Gevaert, Kris, Vandekerckhove, Joël

Abstract Background Migration is an important aspect of cellular behaviour and is therefore widely studied in cell biology. Numerous components are known to participate in this process in a highly...

Caenorhabditis elegans expresses three functional profilins in a tissue-specific manner (2006)

Polet, Debby, Lambrechts, Anja, ONO, K, MAH, A, Peelman, Frank, Vandekerckhove, Joël, ...

Actin interacts with CCT via discrete binding sites: A binding transition-release model for CCT-mediated actin folding (2006)

NEIRYNCK, K, Waterschoot, Davy, Vandekerckhove, Joël, Ampe, Christophe, Rommelaere, Heidi

Mapping of binding site III in the leptin receptor and modeling of a hexameric leptin center dot leptin receptor complex (2006)

Peelman, Frank, Iserentant, Hannes, De Smet, Anne-Sophie, Vandekerckhove, Joël, Zabeau, Lennart, Tavernier, Jan

Identification of the PXW sequence as a structural gatekeeper of the headpiece C-terminal subdomain fold (2006)

Vermeulen, Wim, Van Troys, Marleen, Bourry, David, Dewitte, Daisy, Rossenu, Stefaan, Goethals, Marc, ...

Cell_motility: a cross-platform, open source application for the study of cell motion paths (2006)

Martens, Lennart, MONSIEUR, G, Ampe, Christophe, Gevaert, Kris, Vandekerckhove, Joël

Four stage liquid chromatographic selection of methionyl peptides for peptide-centric proteome analysis: The proteome of human multipotent adult progenitor cells (2006)

Gevaert, Kris, Pinxteren, Jozef, Demol, Hans, Hugelier, Koen, Staes, An, Van Damme, Jozef, ...

A complex interaction pattern of CIS and SOCS2 with the leptin receptor (2006)

Lavens, Delphine, Montoye, Tony, Piessevaux, Julie, Zabeau, Lennart, Vandekerckhove, Joël, Gevaert, Kris, ...

Analysis of leptin signalling in hematopoietic cells using an adapted MAPPIT strategy (2006)

Montoye, Tony, Piessevaux, Julie, Lavens, Delphine, Wauman, Joris, Catteeuw, Dominiek, Vandekerckhove, Joël, ...

Protein processing and other modifications analyzed by diagonal peptide chromatography (2006)

Gevaert, Kris, Van Damme, Petra, Ghesquière, Bart, Vandekerckhove, Joël

A new functional, chemical proteomics technology to identify purine nucleotide binding sites in complex proteomes (2006)

Hanoulle, Xavier, Van Damme, Jozef, Staes, An, MARTENS, L, Goethals, Marc, Vandekerckhove, Joël, ...

Improved tandem mass spectrometric characterization of 3-nitrotyrosine sites in peptides (2006)

Ghesquière, Bart, Goethals, Marc, Van Damme, Jozef, Staes, An, Timmerman, Evy, Vandekerckhove, Joël, ...

A comparison of the HUPO Brain Proteome Project pilot with other proteomics studies (2006)

MARTENS, L, MULLER, M, STEPHAN, C, HAMACHER, M, REIDEGELD, KA, MEYER, HE, ...

Proteome-wide characterization of N-glycosylation events by diagonal chromatography (2006)

Ghesquière, Bart, Van Damme, Jozef, MARTENS, L, Vandekerckhove, Joël, Gevaert, Kris

Functional cross-modulation between SOCS proteins can stimulate cytokine signaling (2006)

Piessevaux, Julie, Lavens, Delphine, MONTOYE, T, Wauman, Joris, Catteeuw, Dominiek, Vandekerckhove, Joël, ...

Multirepeat beta-thymosins (2006)

Van Troys, Marleen, Dhaese, Stien, Vandekerckhove, Joël, Ampe, Christophe

THE ROLE OF PRO62 AND TRP64 FOR HEADPIECE STABILITY (2006)

Bourry, David, VERMEULEN, W, Van Troys, Marleen, DEWITTE, D, ROSSENU, S, Goethals, Marc, ...

The Role of Pro62 and Trp64 for HeadPiece Stability (2006)

Bourry, David, VERMEULEN, W, Van Troys, Marleen, Goethals, Marc, Borremans, Frans, Vandekerckhove, Joël, ...

Profilin-I-ligand interactions influence various aspects of neuronal differentiation (2006)

Lambrechts, Anja, Jonckheere, Veronique, PELEMAN, C, Polet, Debby, De Vos, Winnok, Vandekerckhove, Joël, ...

Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera (2005)

De Hemptinne, Bernard, Gevaert, Kris, Vandekerckhove, Joël, ...

A small animal model harboring a functional human liver cell xenograft would be a useful tool to study human liver cell biology, drug metabolism, and infections with hepatotropic viruses. Here we...

Penetratin-membrane association: W48/R52/W56 shield the peptide from the aqueous phase (2005)

Lensink, Marc, Christiaens, Britt, Vandekerckhove, Joël, PROCHIANTZ, A, Rosseneu, Maryvonne

Enhancement of polymethacrylate-mediated gene delivery by Penetratin (2005)

Christiaens, Bart, Dubruel, Peter, Grooten, Johan, Goethals, Marc, Vandekerckhove, Joël, Schacht, Etienne, ...

Plastins: versatile modulators of actin organization in (patho)physiological cellular processes (2005)

Delanote, Veerle, Vandekerckhove, Joël, Gettemans, Jan

Nuclear actin-binding proteins as modulators of gene transcription (2005)

Gettemans, Jan, Van Impe, Katrien, Delanote, Veerle, HUBERT, T, Vandekerckhove, Joël, De Corte, Veerle

Lysophosphatidic acid affinity chromatography reveals pyruvate kinase as a specific LPA-binding protein (2005)

DESMARET, S, QIAN, L, Vanloo, Berlinda, Meerschaert, Kris, Van Damme, Jozef, Grooten, Johan, ...

A monopartite nuclear localization sequence regulates nuclear targeting of the actin binding protein myopodin (2005)

DE GANCK, A, HUBERT, T, Van Impe, Katrien, Geelen, Danny, Vandekerckhove, Joël, De Corte, Veerle, ...

Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells (2005)

Eyckerman, Sven, Lemmens, Irma, Catteeuw, Dominiek, Verhee, Annick, Vandekerckhove, Joël, Lievens, Sam, ...

Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera (2005)

Meuleman, Philip, LIBBRECHT, L, DE VOS, R, De Hemptinne, Bernard, Gevaert, Kris, Vandekerckhove, Joël, ...

Mapping of the interface between leptin and the leptin receptor CRH2 domain (2005)

ISERENTANT, H, Peelman, Frank, DEFEAU, D, Vandekerckhove, Joël, Zabeau, Lennart, Tavernier, Jan

Leptin receptor activation depends on critical cysteine residues in its fibronectin type III subdomains (2005)

Zabeau, Lennart, DEFEAU, D, ISERENTANT, H, Vandekerckhove, Joël, Peelman, Frank, Tavernier, Jan

Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis (2005)

Van Damme, Petra, Martens, Lennart, Van Damme, Jozef, Hugelier, Koen, Staes, An, Vandekerckhove, Joël, ...

Diagonal reverse-phase chromatography applications in peptide-centric proteomics: Ahead of catalogue-omics? (2005)

Gevaert, Kris, Van Damme, Petra, Martens, Lennart, Vandekerckhove, Joël

Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC (2005)

Gevaert, Kris, Staes, An, Van Damme, Jozef, DE GROOT, S, Hugelier, Koen, Demol, Hans, ...

Do we want our data raw? Including binary mass spectrometry data in public proteomics data repositories (2005)

Martens, Lennart, NESVIZHSKII, AI, HERMJAKOB, H, ADAMSKI, M, OMENN, GS, Vandekerckhove, Joël, ...

PRIDE: The proteomics identifications database (2005)

Martens, Lennart, HERMJAKOB, H, JONES, P, ADAMSKI, M, TAYLOR, C, STATES, D, ...

DBToolkit: processing protein databases for peptide-centric proteomics (2005)

Martens, Lennart, Vandekerckhove, Joël, Gevaert, Kris

The human platelet proteome mapped by peptide-centric proteomics: A functional protein profile (2005)

Martens, Lennart, Van Damme, Petra, Van Damme, Jozef, Staes, An, Timmerman, Evy, Ghesquière, Bart, ...

Molecular basis for dissimilar nuclear trafficking of the actin-bundling protein isoforms T- and L-plastin (2005)

Delanote, Veerle, Van Impe, Katrien, De Corte, Veerle, Bruyneel, Erik, VETTER, G, Boucherie, Ciska, ...

DBToolkit: processing protein databases for peptide-centric proteomics (2005)

Martens, Lennart, Vandekerckhove, Joël, Gevaert, Kris

Summary: DBToolkit is a user-friendly, easily extensible tool that allows the processing of protein sequence databases to peptide-centric sequence databases. This processing is primarily aimed at...

DBToolkit: processing protein databases for peptide-centric proteomics (2005)

Martens, Lennart, Vandekerckhove, Joël, Gevaert, Kris

Summary: DBToolkit is a user-friendly, easily extensible tool that allows the processing of protein sequence databases to peptide-centric sequence databases. This processing is primarily aimed at...

Membrane interaction and cellular internalization of penetratin peptides (2004)

Christiaens, Bart, Grooten, Johan, REUSENS, M, JOLIOT, A, Goethals, Marc, Vandekerckhove, Joël, ...

Buffering properties of cationic polymethacrylates are not the only key to successful gene delivery (2004)

Dubruel, Peter, Christiaens, Bart, Rosseneu, Maryvonne, Vandekerckhove, Joël, Grooten, Johan, Goossens, Vera, ...

Functional analysis of leptin receptor activation using a Janus kinase/signal transducer and activator of transcription complementation assay (2004)

Zabeau, Lennart, Defeau, Delphine, Van Der Heyden, José, Iserentant, Hannes, Vandekerckhove, Joël, Tavernier, Jan

Identification and characterization of the expression of the translation initiation factor 4A (eIF4A) from Drosophila melanogaster (2004)

HERNANDEZ, G, LALIOTI, V, Vandekerckhove, Joël, SIERRA, JM, SANTAREN, JF

Reversible labeling of cysteine-containing peptides allows their specific chromatographic isolation for non-gel proteome studies (2004)

Gevaert, Kris, Ghesquière, Bart, Staes, An, Martens, Lennart, Van Damme, Jozef, Thomas, Grégoire, ...

Design of a fluorescence-activated cell sorting-based Mammalian protein-protein interaction trap (2004)

Lievens, Sam, HEYDEN, J, Vertenten, Els, Plum, Jean, Vandekerckhove, Joël, Tavernier, Jan

The use of proteomics in the study of cell death (2004)

Saelens, Xavier, VAN LOO, G, Gevaert, Kris, Vandekerckhove, Joël, Vandenabeele, Peter

Expression and activity of the nucleotide-binding domains of the human ABCA1 transporter (2004)

Roosbeek, Stein, CASTER, H, LIU, QZ, BERNE, PF, DUVERGER, N, Christiaens, Bart, ...

The effect of alpha-amanitin on the Arabidopsis seed proteome highlights the distinct roles of stored and neosynthesized mRNAs during germination (2004)

RAJJOU, L, GALLARDO, K, DEBEAUJON, I, Vandekerckhove, Joël, JOB, C, JOB, D

Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy (2004)

IROBI, J, Van Impe, Katrien, SEEMAN, P, JORDANOVA, A, DIERICK, I, VERPOORTEN, N, ...

TetraThymosin beta is required for actin dynamics in Caenorhabditis elegans and acts via functionally different actin-binding repeats (2004)

Van Troys, Marleen, ONO, K, Dewitte, Daisy, Jonckheere, Veronique, De Ruyck, Natalie, Vandekerckhove, Joël, ...

Increased importin-beta-dependent nuclear import of the actin modulating protein CapG promotes cell invasion (2004)

De Corte, Veerle, Van Impe, Katrien, Bruyneel, Erik, Boucherie, Ciska, MAREEL, MARCUS, Vandekerckhove, Joël, ...

Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter (2004)

Roosbeek, Stein, Peelman, Frank, Verhee, Annick, Labeur, Christine, CASTER, H, Lensink, Marc, ...

Caspase-dependent, geldanamycin-enhanced cleavage of co-chaperone p23 in leukemic apoptosis (2004)

GAUSDAL, G, GJERTSEN, BT, FLADMARK, KE, Demol, Hans, Vandekerckhove, Joël, DOSKELAND, SO

Proteome analysis of human mesothelial cells during epithelial to mesenchymal transitions induced by shed menstrual effluent (2004)

DEMIR, AY, Demol, Hans, Puype, Magda, DE GOEIJ, AFPM, DUNSELMAN, GAJ, HERRLER, A, ...

Global differential non-gel proteomics by quantitative and stable labeling of tryptic peptides with oxygen-18 (2004)

Staes, An, Demol, Hans, Van Damme, Jozef, Martens, Lennart, Vandekerckhove, Joël, Gevaert, Kris

The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin (2004)

MASSON, N, APPELHOFF, RJ, TUCKERMAN, JR, TIAN, Y, Demol, Hans, Puype, Magda, ...

The folding pathways of actin and tubulins, mechanism of and recognition by the eukaryotic chaperones prefoldin and CCT (2004)

Neirynck, Katrien, Rommelaere, Heidi, Vandekerckhove, Joël, Ampe, Christophe

Structural plasticity of functional actin: Pictures of actin binding protein and polymer interfaces (vol 11, pg 1279, 2004) (2004)

Rommelaere, Heidi, Waterschoot, Davy, NEIRYNCK, K, Vandekerckhove, Joël, Ampe, Christophe

Enhancement of polymethacrylate-mediated gene delivery by penetratin (2004)

Dubruel, Peter, Christiaens, Bart, Rosseneu, Marie, Vandekerckhove, Joël, Schacht, Etienne

Enhancement of polymethacrylate-mediated gene delivery by penetratin (2004)

Dubruel, Peter, Christiaens, Bart, Grooten, Johan, Goethals, Marc, Vandekerckhove, Joël, Schacht, Etienne, ...

Mutated E-cadherin: Genomic and functional characterization in thyroid cells from the KAT family (2004)

ROCHA, AS, De Wever, Olivier, MOREIRA, S, COSTA, MJ, Vandekerckhove, Joël, MAREEL, MARCUS, ...

Syndecan 3 intramembrane proteolysis is presenilin/gamma-secretase-dependent and modulates cytosolic signaling (2003)

Vandekerckhove, Joël

The syndecans play critical roles in several signal transduction pathways. The core proteins of these heparan sulfate proteoglycans are characterized by highly conserved transmembrane and...

Heteromeric MAPPIT: a novel strategy to study modification-dependent protein-protein interactions in mammalian cells (2003)

Lemmens, Irma; U0034260, Eyckerman, Sven, Zabeau, Lennart, Catteeuw, Dominiek, Vertenten, Els, Verschueren, Kristin; U0019093, ...

We recently reported a two-hybrid trap for detecting protein-protein interactions in intact mammalian cells (MAPPIT). The bait protein was fused to a STAT recruitment-deficient, homodimeric cytokine...

β-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility (2003)

Oliveira,Maria José, Van Damme,Jozef, Lauwaet,Tineke, De Corte,Veerle, De Bruyne,Georges, Verschraegen,Gerda, ...

β-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility (2003)

Oliveira, Maria José, Van Damme, Jozef, Lauwaet, Tineke, De Corte, Veerle, De Bruyne, Georges, Verschraegen, Gerda, ...

A kelch beta-propeller featuring as a G beta structural mimic: Reinventing the wheel? (2003)

Gettemans, Jan, Meerschaert, Kris, Vandekerckhove, Joël, De Corte, Veerle

IL-29 Is proteomics heading towards medicine? (2003)

Vandekerckhove, Joël, Van Damme, Jozef, Martens, Lennart, Thomas, Grégoire, Staes, An, Goethals, Marc, ...

Activation-associated secreted proteins are the most abundant antigens in a host protective fraction from Ostertagia ostertagi (2003)

Geldhof, Peter, Vercauteren, Isabel, Gevaert, Kris, Staes, An, KNOX, DP, Vandekerckhove, Joël, ...

Structural plasticity of functional actin: Pictures of actin binding protein and polymer interfaces (2003)

Rommelaere, Heidi, Waterschoot, Davy, Neirynck, Katrien, Vandekerckhove, Joël, Ampe, Christophe

Involvement of sialoadhesin in entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages (2003)

Vanderheijden, Nathalie, Delputte, Peter, Favoreel, Herman, Vandekerckhove, Joël, Van Damme, Jozef, VAN WOENSEL, PA, ...

Autophosphorylation of cGMP-dependent protein kinase type II (2003)

VAANDRAGER, AB, HOGEMA, BM, EDIXHOVEN, M, VAN DEN BURG, CMM, BOT, AGM, KLATT, P, ...

Characterization of the ABCA transporter subfamily: Identification of prokaryotic and eukaryotic members, phylogeny and topology (2003)

Peelman, Frank, Labeur, Christine, Vanloo, Berlinda, Roosbeek, Stein, DEVAUD, C, DUVERGER, N, ...

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides (2003)

Gevaert, Kris, Goethals, Marc, Martens, Lennart, Van Damme, Jozef, Staes, An, Thomas, Grégoire, ...

A phage display-based method for determination of relative affinities of mutants - Application to the actin-binding motifs in thymosin beta 4 and the villin headpiece (2003)

ROSSENU, S, Leyman, Shirley, Dewitte, Daisy, Peelaers, Danny, Jonckheere, Veronique, Van Troys, Marleen, ...

The ins and outs of leptin receptor activation (2003)

Zabeau, Lennart, Lavens, Delphine, Peelman, Frank, Eyckerman, Sven, Vandekerckhove, Joël, Tavernier, Jan

Heteromeric MAPPIT: a novel strategy to study modification-dependent protein-protein interactions in mammalian cells (2003)

Lemmens, Irma, Eyckerman, Sven, Zabeau, Lennart, Catteeuw, Dominiek, Vertenten, Els, VERSCHUEREN, K, ...

Identification of proteins undergoing glutathionylation in oxidatively stressed hepatocytes and hepatoma cells (2003)

FRATELLI, M, Demol, Hans, Puype, Magda, CASAGRANDE, S, VILLA, P, EBERINI, I, ...

Oligomerization controls in tissue-specific manner ligand binding of native, affinity-purified p42(IP4)/centaurin alpha 1 and cytohesins - proteins with high affinity for the messengers D-inositol 1,3,4,5-tetrakisphosphate/phosphatidylinositol 3,4,5-trisphosphate (2003)

STRICKER, R, Vandekerckhove, Joël, KRISHNA, MU, FALCK, JR, HANCK, T, REISER, G

MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1 (2003)

TIMM, T, LI, XY, BIERNAT, J, JIAO, J, MANDELKOW, E, Vandekerckhove, Joël, ...

Proteomics of Medicago truncatula seed development establishes the time frame of diverse metabolic processes related to reserve accumulation (2003)

GALLARDO, K, LE SIGNOR, C, Vandekerckhove, Joël, THOMPSON, RD, BURSTIN, J

The nucleo-cytoplasmic actin-binding protein CapG lacks a nuclear export sequence present in structurally related proteins (2003)

Van Impe, Katrien, De Corte, Veerle, EICHINGER, L, Bruyneel, Erik, MAREEL, MARCUS, Vandekerckhove, Joël, ...

beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility (2003)

OLIVEIRA, MJ, Van Damme, Jozef, Lauwaet, Tineke, De Corte, Veerle, De Bruyne, Georges, Verschraegen, Gerda, ...

Poly-L-glutamic acid derivatives as multifunctional vectors for gene delivery. Part B. Biological evaluation (vol 4, pg 1177, 2003) (2003)

Dubruel, Peter, Dekie, Luc, Christiaens, Bart, DA VANLOO, B, Rosseneu, Maryvonne, Vandekerckhove, Joël, ...

Syndecan 3 intramembrane proteolysis is presenilin/gamma-secretase-dependent and modulates cytosolic signaling (2003)

SCHULZ, JG, ANNAERT, W, Vandekerckhove, Joël, ZIMMERMANN, P, DE STROOPER, B, DAVID, G

A novel cell death pathway as potential therapeutic target for the treatment of cancer (2003)

Van Herreweghe, Franky, Vandekerckhove, Joël, Vancompernolle, Katia

Physicochemical and biological evaluation of cationic polymethacrylates as vectors for gene delivery (2003)

Dubruel, Peter, Christiaens, Bart, Vanloo, Berlinda, BRACKE, K, Rosseneu, Maryvonne, Vandekerckhove, Joël, ...

Protein characterization: analytical approaches and applications to proteomics (2003)

Gevaert, Kris, Vandekerckhove, Joël

Cationic polymethacrylates as vectors for gene delivery: synthesis, physico-chemical and biological evaluation (Poster by P. Dubruel) (2003)

Dubruel, Peter, Christiaens, Bart, Vanloo, Berlinda, Rosseneu, Maryvonne, Vandekerckhove, Joël, Schacht, Etienne

Cationic polymethacrylates as vectors for gene delivery: synthesis, physico-chemical and biological evaluation (Oral Communication by P. Dubruel) (2003)

Dubruel, Peter, Christiaens, Bart, Vanloo, Berlinda, Rosseneu, Maryvonne, Vandekerckhove, Joël, Schacht, Etienne

Heteromeric MAPPIT: a novel strategy to study modification-dependent protein-protein interactions in mammalian cells (2003)

Lemmens, Irma, Eyckerman, Sven, Zabeau, Lennart, Catteeuw, Dominiek, Vertenten, Els, Verschueren, Kristin, ...

We recently reported a two‐hybrid trap for detecting protein–protein interactions in intact mammalian cells (MAPPIT). The bait protein was fused to a STAT recruitment‐deficient,...

The expression, processing and localization of polymorphic membrane proteins in Chlamydia pneumoniaestrain CWL029 (2002)

Vandahl, Brian, Pedersen, Anna, Gevaert, Kris, Holm, Arne, Vandekerckhove, Joël, Christiansen, Gunna, ...

Abstract Background Chlamydiae are obligate intracellular bacteria, which are important human pathogens. Genome sequences of C. trachomatis and C. pneumoniae have revealed the presence of a Chlamydia...

PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane (2002)

Meerschaert, Kris, Leenaerts, Iris, Small, J Victor, Vandekerckhove, Joël, ...

PDZ proteins organize multiprotein signaling complexes. According to current views, PDZ domains engage in protein-protein interactions. Here we show that the PDZ domains of several proteins bind...

Mutational analysis of human profilin I reveals a second PI(4,5)-P2 binding site neighbouring the poly(L-proline) binding site. (2002)

Lambrechts, Anja, JONCKHEERE, V, DEWITTE, D, Vandekerckhove, Joël, Ampe, Christophe

Comparison of leptin- and interleukin-6-regulated expression of the rPAP gene family: evidence for differential co-regulatory signals. (2002)

Broekaert, Daniël, Eyckerman, Sven, Lavens, Delphine, VERHEE, A, Waelput, Wim, Vandekerckhove, Joël, ...

Tryptophan fluorescence study of the interaction of penetratin peptides with model membranes. (2002)

Christiaens, Bart, SYMOENS, S, VANDERHEYDEN, S, ENGELBORGHS, Y, JOLIOT, A, PROCHIANTZ, A, ...

Gelsolin-induced epithelial cell invasion is dependent on Ras-Rac signaling. (2002)

De Corte, Veerle, Bruyneel, Erik, Boucherie, Ciska, MAREEL, MARCUS, Vandekerckhove, Joël, Gettemans, Jan

Design and use of a mammalian protein-protein interaction trap (MAPPIT) (2002)

Eyckerman, Sven, Lemmens, Irma, Lievens, Sam, VERHEE, A, Vandekerckhove, Joël, ...

Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes. (2002)

FRATELLI, M, Demol, Hans, Puype, Magda, CASAGRANDE, S, EBERINI, I, SALMONA, M, ...

Proteomics of Arabidopsis seed germination. A comparative study of wild-type and gibberellin-deficient seeds. (2002)

GALLARDO, K, JOB, C, GROOT, S, Puype, Magda, Demol, Hans, Vandekerckhove, Joël, ...

Importance of methionine biosynthesis for Arabidopsis seed germination and seedling growth. (2002)

GALLARDO, K, JOB, C, GROOT, S, Puype, Magda, Demol, Hans, Vandekerckhove, Joël, ...

Distinct protein patterns associated with Listeria monocytogenes InIA- or InIB-phagosomes. (2002)

PIZZARO-CERDA, J, JONQUIERES, R, GOUIN, E, Vandekerckhove, Joël, GARIN, J, COSSART, P

Plasmin produces an E-cadherin fragment that stimulates cancer cell invasion. (2002)

RYNIERS, F, Stove, Christophe, GOETHALS, M, BRACKENIER, L, NOE, V, Bracke, Marc, ...

Comparative proteome analysis of Chlamydia trachomatis serovar A, D and L2. (2002)

SHAW, AC, Gevaert, Kris, Demol, Hans, HOORELBEKE, B, Vandekerckhove, Joël, LARSEN, MR, ...

Characterization of a secreted Chlamydia protease. (2002)

SHAW, AC, VANDAHL, BB, LARSEN, MR, ROEPSTORFF, P, Gevaert, Kris, Vandekerckhove, Joël, ...

Fragmin60 encodes an actin-binding protein with a C2 domain and controls actin Thr-203 phosphorylation in Physarum plasmodia and sclerotia. (2002)

Sklyarova, Tatyana, De Corte, Veerle, Meerschaert, Kris, Devriendt, Liesbeth, Vanloo, Berlinda, BAILEY, J, ...

unc-53 controls longitudinal migration in C-elegans. (2002)

STRINGHAM, E, Pujol, Nathalie, Vandekerckhove, Joël, Bogaert, Thierry

MAPPIT: a cytokine receptor-based two-hybrid method in mammalian cells. (2002)

Tavernier, Jan, Eyckerman, Sven, Lemmens, Irma, Vandekerckhove, Joël, Van Ostade, Xaveer

Selected BTB/POZ-kelch proteins bind ATP. (2002)

T'jampens, Davy, Devriendt, Liesbeth, De Corte, Veerle, Vandekerckhove, Joël, Gettemans, Jan

The expression, processing and localization of polymorphic membrane proteins in Chlamydia pneumoniae strain CWL029. (2002)

VANDAHL, BB, PEDERSEN, AS, GEVAERT, K, HOLM, A, Vandekerckhove, Joël, CHRISTIANSEN, G, ...

Oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population. (2002)

VANVOOREN, V, UCHINO, S, DUPREZ, L, COSTA, MJ, Vandekerckhove, Joël, PARMA, J, ...

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methyl glyoxal-derived AGE. (2002)

Van Herreweghe, Franky, MAO, JQ, CHAPLEN, F, Grooten, Johan, Gevaert, Kris, Vandekerckhove, Joël, ...

A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid. (2002)

Van Loo, Geert, Demol, Hans, Van Gurp, Maria, HOORELBEKE, B, Schotte, Peter, Beyaert, Rudi, ...

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity. (2002)

Van Loo, Geert, Van Gurp, Maria, Depuydt, Bart, SRINIVASULA, SM, RODRIGUEZ, I, ALNEMRI, ES, ...

PIP2-PDZ domain binding controls the association of syntenin with the plasma membrane. (2002)

ZIMMERMANN, P, Meerschaert, Kris, REEKMANS, G, LEENAERTS, I, SMALL, JV, Vandekerckhove, Joël, ...

Chromatographic isolation of methionine-containing peptides for gel-free proteome analysis - Identification of more than 800 Escherichia coli proteins (2002)

Gevaert, Kris, Van Damme, Jozef, Goethals, Marc, Thomas, Grégoire, HOORELBEKE, B, Demol, Hans, ...

Interaction of nanostructured polyelectrolyte complexes with cells (Poster by P. Dubruel) (2002)

Dubruel, Peter, Christiaens, Bart, Vanloo, Berlinda, Bracke, Kristof, Vandekerckhove, Joël, Rosseneu, Maryvonne, ...

An ASP-like protein is the most abundant antigen in a host protective fraction from Ostertagia ostertagi (2002)

Geldhof, Peter, Vercauteren, Isabel, Gevaert, Kris, Staes, A, Knox, D, Claerebout, Edwin, ...

Partial purification and identification of GDP-mannose 3', 5'-epimerase of Arabidopsis thaliana, a key enzyme of the plant vitamin C pathway. (2001)

Wolucka, Beata, PERSIAU, G, Van Doorsselaere, Jan, Davey, Mark, Demol, Hans, Vandekerckhove, Joël, ...

A novel receptor-mediated regulation mechanism of type I inositol polyphosphate 5-phosphatase by calcium/calmodulindependent protein kinase II phosphorylation. (2001)

COMMUNI, D, Gevaert, Kris, Demol, Hans, Vandekerckhove, Joël, ERNEUX, C

Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16. (2001)

DAUB, H, Gevaert, Kris, Vandekerckhove, Joël, SOBEL, A, HALL, A

Comparison of the aggregation properties, secondary structure and apoptotic effects of wild-type, Flemish and Dutch N-terminally truncated amyloid beta peptides. (2001)

Demeester, Nathalie, MERTENS, C, CASTER, H, GOETHALS, M, Vandekerckhove, Joël, Rosseneu, Maryvonne, ...

A hydrophobic cluster at the surface of the human plasma phospholipid transfer protein is critical for activity on high density lipoproteins. (2001)

DESRUMAUX, C, Labeur, Christine, VERHEE, A, Tavernier, Jan, Vandekerckhove, Joël, Rosseneu, Maryvonne, ...

ApoE protects cortical neurones against neurotoxicity induced by the non-fibrillar C-terminal domain of the amyloid-beta peptide. (2001)

DROUET, B, FIFRE, A, PINCON-RAYMOND, M, Vandekerckhove, Joël, Rosseneu, Maryvonne, GUEANT, JL, ...

Design and application of a cytokine-receptor-based interaction trap. (2001)

Eyckerman, Sven, VERHEE, A, Lemmens, Irma, Van Ostade, Xaveer, Vandekerckhove, Joël, ...

Proteomic analysis of Arabidopsis seed germination and priming. (2001)

GALLARDO, K, JOB, C, GROOT, S, Puype, Magda, Demol, Hans, Vandekerckhove, Joël, ...

Protein identification based on matrix assisted laser desorption/ionization-post source decay-mass spectrometry. (2001)

Gevaert, Kris, Demol, Hans, Martens, Lennart, HOORELBEKE, B, Puype, Magda, GOETHALS, M, ...

Phosphorylation of LHI beta during membrane synthesis in the photosynthetic bacterium Rhodovulum sulfidophilum. (2001)

IUSTMAN, LJR, PUCHEU, NL, KERBER, NL, Vandekerckhove, Joël, TADROS, MH, GARCIA, AF

Cdc42 induces filopodia by promoting the formation of an IRSp53 : Mena complex. (2001)

KRUGMANN, S, JORDENS, I, Gevaert, Kris, DRIESSENS, M, Vandekerckhove, Joël, HALL, A

Effect of mutations of N- and C-terminal charged residues on the activity of LCAT. (2001)

Peelman, Frank, Vanloo, Berlinda, Verschelde, Jean-Luc, Labeur, Christine, CASTER, H, TAVEIRNE, J, ...

Three arginine residues in apolipoprotein A-I are critical for activation of lecithin : cholesterol acyltransferase. (2001)

Roosbeek, Stein, Vanloo, Berlinda, DUVERGER, N, CASTER, H, BREYNE, J, DE BEUN, I, ...

Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions. (2001)

SHAV-TAL, Y, COHEN, M, LAPTER, S, DYE, B, PATTON, JG, Vandekerckhove, Joël, ...

Proteome analysis of the Chlamydia pneumoniae elementary body. (2001)

VANDAHL, BB, BIRKELUND, S, Demol, Hans, HOORELBEKE, B, CHRISTIANSEN, G, Vandekerckhove, Joël, ...

Time-dependent expression and processing of a hypothetical protein of possible importance for regulation of the Chlamydia pneumoniae developmental cycle. (2001)

VANDAHL, BB, Gevaert, Kris, Demol, Hans, HOORELBEKE, B, HOLM, A, Vandekerckhove, Joël, ...

Endonuclease G : a mitochondrial protein released in apoptosis and involved in caspaseindependent DNA degradation (2001)

Van Loo, Geert, Schotte, Peter, Van Gurp, Maria, Demol, Hans, HOORELBEKE, B, Gevaert, Kris, ...

A mediator role for metallothionein in tumor necrosis factor-induced lethal shock. (2001)

WAELPUT, W, Broekaert, Daniël, Vandekerckhove, Joël, Brouckaert, Peter, Tavernier, Jan, Libert, Claude

Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy. (2001)

Wielockx, Ben, LANNOY, K, SHAPIRO, SD, ITOH, T, ITOHARA, S, Vandekerckhove, Joël, ...

Neutralizing monoclonal antibodies can potentiate IL-5 signaling. (2001)

Zabeau, Lennart, Broekaert, Daniël, VERHEE, A, Vandekerckhove, Joël, WU, SJ, ...

Prefoldin recognition motifs in the nonhomologous proteins of the actin and tubulin families. (2001)

Rommelaere, Heidi, De Neve, Myriam, Neirynck, Katrien, PEELAERS, D, WATERSCHOOT, D, GOETHALS, M, ...

Effect of maturation and aging on beta-adrenergic signal transduction in rat kidney and liver. (2000)

Fraeyman, Norbert, Van Ermen, Ann, Bazan, Ariane, VANDERHEYDEN, P, VAN EMMELO, L, ...

Headgroup specificity of lecithin cholesterol acyltransferase for monomeric and vesicular phospholipids. (2000)

Christiaens, Bart, Vanloo, Berlinda, GOUYETTE, C, Van Vynckt, Inge, CASTER, H, TAVEIRNE, J, ...

Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin : cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease. (2000)

Demeester, Nathalie, CASTRO, G, DESRUMAUX, C, DE GEITERE, C, FRUCHART, JC, SANTENS, P, ...

A fast and convenient MALDI-MS based proteomic approach: identification of components scaffolded by the actin cytoskeleton of activated human thrombocytes. (2000)

Gevaert, Kris, EGGERMONT, L, Demol, Hans, Vandekerckhove, Joël

Techniques for sample preparation including methods for concentrating peptide samples. (2000)

Gevaert, Kris, Houthaeve, Tony, Vandekerckhove, Joël

cAMP-dependent protein kinase phosphorylation of EVL, a mena/VASP relative, regulates its interaction with actin and SH3 domains. (2000)

Lambrechts, Anja, KWIATKOWSKI, AV, LANIER, LM, BEAR, JE, Vandekerckhove, Joël, Ampe, Christophe, ...

The amino-terminal domain of the Golgi protein Giantin interacts directly with the vesicle-tethering protein p115. (2000)

LESA, GM, SEEMANN, J, SHORTER, J, Vandekerckhove, Joël, WARREN, G

Characterization of recombinant wild type and site-directed mutations of apolipoprotein C-III: Lipid binding, displacement of ApoE, and inhibition of lipoprotein lipase. (2000)

LIU, HQ, TALMUD, PJ, LINS, L, BRASSEUR, R, OLIVECRONA, G, Peelman, Frank, ...

A plant plasma membrane H+-ATPase expressed in yeast is activated by phosphorylation at its penultimate residue and binding of 14-3-3 regulatory proteins in the absence of fusicoccin. (2000)

MAUDOUX, O, BATOKO, H, OECKING, C, Gevaert, Kris, Vandekerckhove, Joël, BOUTRY, M, ...

Structure and function of lecithin cholesterol acyl transferase: new insights from structural predictions and animal models. (2000)

Peelman, Frank, Vandekerckhove, Joël, Rosseneu, Maryvonne

A nonfibrillar form of the fusogenic prion protein fragment [118-135] induces apoptotic cell death in rat cortical neurons. (2000)

PILLOT, T, DROUET, B, PINCON-RAYMOND, RL, Vandekerckhove, Joël, ROSSENEU, T, CHAMBAZ, J

Polypeptides differentially expressed in imaginal discs define the peroxiredoxin family of genes in Drosophila. (2000)

RODRIGUEZ, J, AGUDO, M, Van Damme, Jozef, Vandekerckhove, Joël, SANTAREN, JF

Secretion of biologically active murine interleukin-10 by Lactococcus lactis. (2000)

Schotte, Lieven, Steidler, Lothar, Vandekerckhove, Joël, Remaut, Erik

Targeting of aminopeptidase I to the yeast vacuole ts mediated by Ssa1p, a cytosolic member of the 70-kDa stress protein family. (2000)

SILLES, E, MAZON, MJ, Gevaert, Kris, GOETHALS, M, Vandekerckhove, Joël, LEBER, R, ...

Interleukin 5 regulates the isoform expression of its own receptor alpha-subunit. (2000)

Tavernier, Jan, VERHEE, A, BRUSSELLE, G, Van Ostade, Xaveer, Vandekerckhove, Joël, ...

Relationship between structure and biochemical phenotype of lecithin : cholesterol acyltransferase (LCAT) mutants causing fish-eye disease. (2000)

Vanloo, Berlinda, Peelman, Frank, Deschuymere, Kristof, TAVEIRNE, J, VERHEE, A, GOUYETTE, C, ...

A sensitive and versatile bioassay for ligands that signal through receptor clustering. (2000)

Van Ostade, Xaveer, Schauvliege, Liesbeth, Pattyn, Els, VERHEE, A, Vandekerckhove, Joël, Tavernier, Jan

The competitive interaction of actin and PIP2 with actophorin is based on overlapping target sites: Design of a gain-of-function mutant. (2000)

Van Troys, Marleen, DEWITTE, D, Verschelde, Jean-Luc, GOETHALS, M, Vandekerckhove, Joël, Ampe, Christophe

A novel endogenous PP2C-like phosphatase dephosphorylates casein kinase II-phosphorylated Physarum fragmin. (2000)

WAELKENS, E, De Corte, Veerle, MERLEVEDE, W, Vandekerckhove, Joël, Gettemans, Jan

Apoptosis induced in neuronal cells by C-terminal amyloid beta-fragments is correlated with their aggregation properties in phospholipid membranes. (2000)

DEMEESTER, N, BAIER, G, ENZINGER, C, GOETHALS, M, Vandekerckhove, Joël, Rosseneu, Maryvonne, ...

Protein identification methods in proteomics. (2000)

Gevaert, Kris, Vandekerckhove, Joël

Identification and expression analysis of leptin-regulated immediate early response and late target genes. (2000)

WAELPUT, W, VERHEE, A, Broekaert, Daniël, Eyckerman, Sven, Vandekerckhove, Joël, BEATTIE, JH, ...

Structural requirements for thymosin beta 4 in its contact with actin - An NMR-analysis of thymosin beta 4 mutants in solution and correlation with their biological activity. (2000)

SIMENEL, C, Van Troys, Marleen, Vandekerckhove, Joël, Ampe, Christophe, DELEPIERRE, M

Enhanced proteolysis of pre-mRNA splicing factors in myeloid cells. (2000)

SHAV-TAL, Y, LEE, BC, HAIM, SB, Vandekerckhove, Joël, ZIPORI, D

Profilin II is alternatively spliced, resulting in profilin isoforms that are differentially expressed and have distinct biochemical properties. (2000)

Lambrechts, Anja, BRAUN, A, JONCKHEERE, V, ASZODI, A, LANIER, LM, ROBBENS, J, ...

Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor. (2000)

Eyckerman, Sven, Broekaert, Daniël, VERHEE, A, Vandekerckhove, Joël, Tavernier, Jan

Dimerization of the interferon type I receptor IFNaR2-2 is sufficient for induction of interferon effector genes but not for full antiviral activity. (1999)

PATTYN, E, VAN OSTADE, X, SCHAUVLIEGE, L, VERHEE, A, Kalai, Michaël, Vandekerckhove, Joël, ...

Actin and actin filaments (1999)

Ampe, Christophe, Vandekerckhove, Joël

Contribution of the hydrophobicity gradient to the secondary structure and activity of fusogenic peptides. (1999)

Decout, Anne, Labeur, Christine, Vanloo, Berlinda, GOETHALS, M, Vandekerckhove, Joël, BRASSEUR, R, ...

Villin function in the organization of the actin cytoskeleton - Correlation of in vivo effects to its biochemical activities in vitro. (1999)

FRIEDERICH, E, Vancompernolle, Katia, LOUVARD, D, Vandekerckhove, Joël

Dimerisation of the interferon type 1 receptor IFNaR2 subunit is sufficient for induction of interferon effector genes, but not for antiviral activity. (1999)

Pattyn, Els, Van Ostade, Xaveer, Schauvliege, Liesbeth, VERHEE, A, Vandekerckhove, Joël, Tavernier, Jan

Characterisation of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase. (1999)

Vanloo, Berlinda, Peelman, Frank, Labeur, Christine, Vandekerckhove, Joël, Tavernier, Jan, Rosseneu, Maryvonne

beta-amyloid peptide interacts specifically with the carboxy-terminal domain of human apolipoprotein E: Relevance to Alzheimer's disease. (1999)

PILLOT, T, GOETHALS, M, NAJIB, J, Labeur, Christine, LINS, L, CHAMBAZ, J, ...

The crystal structure of the Physarum polycephalum actin-fragmin kinase: an atypical protein kinase with a specialized substrate-binding domain. (1999)

STEINBACHER, S, HOF, P, EICHINGER, L, SCHLEICHER, M, Gettemans, Jan, Vandekerckhove, Joël, ...

Analysis of the Expression Pattern of Human Interleukin-5 Receptor a Isoforms in Vitro (1999)

Tavernier, Jan, VERHEE, A, Vandekerckhove, Joël, Van Ostade, Xaveer

Physarum amoebae express a distinct fragmin-like actin-binding protein that controls in vitro phosphorylation of actin by the actin-fragmin kinase. (1999)

T'jampens, Davy, BAILEY, J, COOK, LJ, CONSTANTIN, B, Vandekerckhove, Joël, Gettemans, Jan

The cell surface expression level of the human interleukin-5 receptor alpha subunit determines the agonistic/antagonistic balance of the human interleukin-5 E13Q mutein. (1999)

Van Ostade, Xaveer, VERHEE, A, Vandekerckhove, Joël, Tavernier, Jan

Structural modules in actin binding proteins: towards a new classification. (1999)

Van Troys, Marleen, Vandekerckhove, Joël, Ampe, Christophe

Inhibition of adhesion and induction of epithelial cell invasion by HAV-containing E-cadherin-specific peptides. (1999)

NOE, V, WILLEMS, J, Vandekerckhove, Joël, Van Roy, Frans, Bruyneel, Erik, MAREEL, MARCUS

Effects of natural mutations in lecithin : cholesterol acyltransferase on the enzyme structure and activity. (1999)

Peelman, Frank, Verschelde, Jean-Luc, Vanloo, Berlinda, Ampe, Christophe, Labeur, Christine, Tavernier, Jan, ...

Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: A mass spectrometric approach. (1999)

De Corte, Veerle, Demol, Hans, GOETHALS, M, Van Damme, Jozef, Gettemans, Jan, Vandekerckhove, Joël

The cytosolic class II chaperonin CCT recognizes delineated hydrophobic sequences in its target proteins. (1999)

Rommelaere, Heidi, De Neve, Myriam, MELKI, R, Vandekerckhove, Joël, Ampe, Christophe

Dimerization of profilin II upon binding the (GP(5))(3) peptide from VASP overcomes the inhibition of actin nucleation by profilin II and thymosin beta 4. (1999)

JONCKHEERE, V, Lambrechts, Anja, Vandekerckhove, Joël, Ampe, Christophe

Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT). (1999)

Peelman, Frank, VANLOO, B, PEREZ-MENDEZ, O, DECOUT, A, VERSCHELDE, JL, Labeur, Christine, ...

LCAT defects and low HDL levels. (1999)

Rosseneu, Maryvonne, Peelman, Frank, VERSCHELDE, JL, VANLOO, B, Labeur, Christine, Tavernier, Jan, ...

Molecular determinants of the interaction between the C-terminal domain of Alzheimer's beta-amyloid peptide and apolipoprotein E alpha-helices. (1999)

LINS, L, THOMAS-SOUMARMON, A, PILLOT, T, Vandekerckhove, Joël, Rosseneu, Maryvonne, BRASSEUR, R

Analysis of Tyr to Phe and the fa/fa mutations in the leptin receptor in PC12 cells. (1999)

Eyckerman, Sven, WAELPUT, W, VERHEE, A, Broekaert, Daniël, Vandekerckhove, Joël, Tavernier, Jan

The nonfibrillar amyloid beta-peptide induces apoptotic neuronal cell death: Involvement of its C-terminal fusogenic domain. (1999)

PILLOT, T, DROUET, B, QUEILLE, S, Labeur, Christine, Vandekerckhove, Joël, Rosseneu, Maryvonne, ...

Lipids, apolipoproteins and LCAT in cerebrospinal fluid of normal individuals and patients with Alzhelmer's disease (1999)

Labeur, Christine, SANTENS, P, DEMEESTER, N, Tilleman, Kelly, Vandekerckhove, Joël, Rosseneu, Maryvonne

Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT) (1999)

Peelman, Frank, Vanloo, Berlinda, Perez-Mendez, Oscar, Decout, Anne, Verschelde, Jean-Luc, Labeur, Christine, ...

Lecithin cholesterol acyltransferase (LCAT) is an interfacial enzyme active on both high-density (HDL) and low-density lipoproteins (LDL). Threading alignments of LCAT with lipases suggest that...

Proteolytic mapping of kinesin/ncd-microtubule interface: nucleotide-dependent conformational changes in the loops L8 and L12. (1998)

ALONSO, MC, Van Damme, Jozef, Vandekerckhove, Joël, CROSS, RA

A proposed architecture for lecithin cholesterol acyl transferase (LCAT): Identification of the catalytic triad and molecular modeling. (1998)

Peelman, Frank, VINAIMONT, N, VERHEE, A, VANLOO, B, VERSCHELDE, JL, Labeur, Christine, ...

Analysis of three human interleukin 5 structures suggests a possible receptor binding mechanism. (1998)

VERSCHELDE, JL, Ampe, Christophe, Guisez, Yves, OEFNER, C, Vandekerckhove, Joël, Tavernier, Jan

Epithelial and fibroblastoid cells contain numerous cell-type specific putative microtubule-regulating proteins, among which are ezrin and fodrin. (1998)

SHESTAKOVA, E, Vandekerckhove, Joël, DE MEY, JR

Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. (1998)

VAINBERG, IE, LEWIS, SA, ROMMELAERE, H, Ampe, Christophe, Vandekerckhove, Joël, KLEIN, HL, ...

Enhanced efficiency of a targeted fusogenic peptide. (1998)

DECOUT, A, Labeur, Christine, GOETHALS, M, BRASSEUR, R, Vandekerckhove, Joël, Rosseneu, Maryvonne

Disruption of the actin cytoskeleton of mammalian cells by the capping complex actin-fragmin is inhibited by actin phosphorylation and regulated by Ca2+ ions. (1998)

CONSTANTIN, B, MEERSCHAERT, K, Vandekerckhove, Joël, Gettemans, Jan

Murine adseverin (D5), a novel member of the gelsolin family, and murine adseverin are induced by interleukin-9 in T-helper lymphocytes. (1998)

ROBBENS, J, LOUAHED, J, DE PESTEL, K, VAN COLEN, I, Ampe, Christophe, Vandekerckhove, Joël, ...

Displacement of apo A-I from HDL by apo A-II or its C-terminal helix promotes the formation of pre-beta(1) migrating particles and decreases LCAT activation. (1998)

Labeur, Christine, LAMBERT, G, VAN CAUTEREN, T, DUVERGER, N, VANLOO, B, CHAMBAZ, J, ...

Contribution of the hydrophobicity gradient of an amphipathic peptide to its mode of association with lipids. (1998)

PEREZ-MENDEZ, O, VANLOO, B, DECOUT, A, GOETHALS, M, Peelman, Frank, Vandekerckhove, Joël, ...

Cathepsin B-mediated activation of the proinflammatory caspase-11. (1998)

Schotte, Peter, Van Criekinge, Wim, Van De Craen, Marc, Van Loo, Geert, Desmedt, Marjory, Grooten, Johan, ...

Gelsolin and functionally similar actin-binding proteins are regulated by lysophosphatidic acid. (1998)

MEERSCHAERT, K, DE CORTE, V, DE VILLE, Y, Vandekerckhove, Joël, Gettemans, Jan

Effects of natural mutations in lecithin cholesterol acyl transferase on the enzyme structure and activity (1998)

Peelman, Frank, VERSCHELDE, JL, Vanloo, Berlinda, Ampe, Christophe, Labeur, Christine, Tavernier, Jan, ...

A peptide concentration and purification method for protein characterization in the subpicomole range using matrix assisted laser desorption/ionization postsource decay (MALDI-PSD) sequencing (1998)

Gevaert, Kris, Demol, Hans, Sklyarova, Tatyana, Vandekerckhove, Joël, HOUTHAEVE, T

The 118-135 peptide lot the human prion protein forms amyloid fibrils and induces liposome fusion. (1997)

PILLOT, T, LINS, L, GOETHALS, M, Vanloo, Berlinda, BAERT, J, Vandekerckhove, Joël, ...

Analogous F-actin binding by cofilin and gelsolin segment 2 substantiates their structural relationship. (1997)

Van Troys, Marleen, DEWITTE, D, Verschelde, Jean-Luc, GOETHALS, M, Vandekerckhove, Joël, Ampe, Christophe

Peptides adsorbed on reverse-phase chromatographic beads as targets for femtomole sequencing by post-source decay matrix assisted laser desorption ionization-reflectron time of flight mass spectrometry (MALDI-RETOF-MS). (1997)

Gevaert, Kris, Demol, Hans, Puype, Magda, Broekaert, Daniël, De Boeck, Stefaan, Houthaeve, Tony, ...

Identification and characterization of the 2-enoyl-CoA hydratases involved in peroxisomal beta-oxidation in rat liver. (1997)

DIEUAIDENOUBHANI, M, NOVIKOV, D, Vandekerckhove, Joël, VANVELDHOVEN, PP, MANNAERTS, GP

An effective potential for calculating free energies .1. General concepts and approximations. (1997)

Verschelde, Henri, Schelstraete, Sigurd, Vandekerckhove, Joël, VERSCHELDE, JL

Phosphatidylinositol 4,5-bisphosphate specifically stimulates PP60(c-src) catalyzed phosphorylation of gelsolin and related actin-binding proteins. (1997)

DECORTE, V, Gettemans, Jan, Vandekerckhove, Joël

Specific modulation of the fusogenic properties of the Alzheimer beta-amyloid peptide by apolipoprotein E isoforms. (1997)

PILLOT, T, GOETHALS, M, Vanloo, Berlinda, LINS, L, BRASSEUR, R, Vandekerckhove, Joël, ...

The mammalian profilin isoforms display complementary affinities for PIP2 and proline-rich sequences. (1997)

Lambrechts, Anja, Verschelde, Jean-Luc, JONCKHEERE, V, GOETHALS, M, Vandekerckhove, Joël, Ampe, Christophe

Aspartic proteinase genes in the Brassicaceae Arabidopsis thaliana and Brassica napus. (1997)

DHONDT, K, STACK, S, GUTTERIDGE, S, Vandekerckhove, Joël, KREBBERS, E, GAL, S

The photoactivatable inhibitor 7-azido-8-idoketanserin labels the N terminus of the vesicular monoamine transporter from bovine chromaffin granules. (1997)

SAGNE, C, ISAMBERT, MF, Vandekerckhove, Joël, HENRY, JP, GASNIER, B

Ca2+-dependent interaction of S100A2 with muscle and nonmuscle tropomyosins. (1997)

GIMONA, M, LANDO, Z, DOLGINOV, Y, Vandekerckhove, Joël, KOBAYASHI, R, SOBIESZEK, A, ...

Folding of the presequence of yeast pAPI into an amphipathic helix determines transport of the protein from the cytosol to the vacuole. (1997)

MARTINEZ, E, JIMENEZ, MA, SEGUIREAL, B, Vandekerckhove, Joël, SANDOVAL, IV

Peptides in membranes: Tipping the balance of membrane stability. (1997)

BRASSEUR, R, PILLOT, T, LINS, L, Vandekerckhove, Joël, Rosseneu, Maryvonne

Identification of two regions in the N-terminal domain of ActA involved in the actin comet tail formation by Listeria monocytogenes. (1997)

LASA, I, GOUIN, E, GOETHALS, M, Vancompernolle, Katia, DAVID, V, Vandekerckhove, Joël, ...

Molecular cloning, over-expression, developmental regulation and immunolocalization of fragminP, a gelsolin-related actin-binding protein from Physarum polycephalum plasmodia. (1997)

TJAMPENS, D, Meerschaert, Kris, CONSTANTIN, B, BAILEY, J, COOK, LJ, DECORTE, V, ...

Apolipoprotein E inhibits liposome fusion induced by the Alzheimer's beta-amyloid peptide. (1997)

PILLOT, T, BRASSEUR, R, Vandekerckhove, Joël, Rosseneu, Maryvonne

Molecular analysis of the Rhodobacter capsulatus chaperone dnaKJ operon: Purification and characterization of DnaK. (1997)

NICKEL, CM, Vandekerckhove, Joël, BEYER, P, TADROS, MH

Novel techniques for identification and characterization of proteins loaded on gels in femtomole amounts. (1997)

Gevaert, Kris, Demol, Hans, Verschelde, Jean-Luc, VANDAMME, J, DEBOECK, S, Vandekerckhove, Joël

A phage display technique for a fast, sensitive, and systematic investigation of protein-protein interactions. (1997)

Rossenu, Stefaan, DEWITTE, D, Vandekerckhove, Joël, Ampe, Christophe

An abscisic-acid- and salt-stress-responsive rice cDNA from a novel plant gene family. (1997)

Moons, Ann, Gielen, Jan, Vandekerckhove, Joël, Van Der Straeten, Dominique, Gheysen, Godelieve, Van Montagu, Marc

GRASP65, a protein involved in the stacking of Golgi cisternae. (1997)

BARR, FA, Puype, Magda, Vandekerckhove, Joël, WARREN, G

Structural and functional properties of the 154-171 wild-type and variant peptides of human lecithin-cholesterol acyltransferase. (1997)

Peelman, Frank, GOETHALS, M, VANLOO, B, Labeur, Christine, BRASSEUR, R, Vandekerckhove, Joël, ...

The actin binding site of thymosin beta 4 mapped by mutational analysis. (1996)

VANTROYS, M, DEWITTE, D, GOETHALS, M, CARLIER, MF, Vandekerckhove, Joël, Ampe, Christophe

Analysis of the catalytic site of the actin ADP-ribosylating Clostridium perfringens iota toxin. (1996)

VANDAMME, J, JUNG, M, HOFMANN, F, JUST, I, Vandekerckhove, Joël, AKTORIES, K

T beta(4) is not a simple G-actin sequestering protein and interacts with F-actin at high concentration. (1996)

CARLIER, MF, DIDRY, D, ERK, I, LEPAULT, J, VANTROYS, ML, Vandekerckhove, Joël, ...

Fragmin, a microfilament regulatory protein from Physarum polycephalum, is phosphorylated by casein kinase II-type enzymes. (1996)

DECORTE, V, Gettemans, Jan, DEVILLE, Y, WAELKENS, E, Vandekerckhove, Joël

Single-step purification of two functional human apolipoprotein E variants hyperexpressed in Escherichia coli. (1996)

PILLOT, T, BARBIER, A, VISVIKIS, A, LOZACH, K, Rosseneu, Maryvonne, Vandekerckhove, Joël, ...

Structural analysis and identification of gel-purified proteins, available in the femtomole range, using a novel computer program for peptide sequence assignment, by matrix-assisted laser desorption ionization reflectron time-of-flight mass spectrometry. (1996)

Gevaert, Kris, VERSCHELDE, JL, Puype, Magda, VANDAMME, J, GOETHALS, M, DEBOECK, S, ...

Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking. (1996)

BLUM, R, FEICK, P, Puype, Magda, Vandekerckhove, Joël, KLENGEL, R, NASTAINCZYK, W, ...

Purification and characterization of chaperonin 60 and heat-shock protein 70 from chromoplasts of Narcissus pseudonarcissus - Involvement of heat-shock protein 70 in a soluble protein complex containing phytoene desaturase. (1996)

BONK, M, TADROS, M, Vandekerckhove, Joël, ALBABILI, S, BEYER, P

Pathway leading to correctly folded beta-tubulin. (1996)

TIAN, GL, HUANG, Y, Rommelaere, Heidi, Vandekerckhove, Joël, Ampe, Christophe, COWAN, NJ

Cofactor A is a molecular chaperone required for beta-tubulin folding: Functional and structural characterization. (1996)

MELKI, R, Rommelaere, Heidi, LEGUY, R, Vandekerckhove, Joël, Ampe, Christophe

Identification of two Physarum casein kinase II enzymes that phosphorylate fragmin, an endogenous actin-binding protein. (1996)

DECORTE, V, Gettemans, Jan, DEVILLE, Y, WAELKENS, E, AGOSTINIS, P, Vandekerckhove, Joël

Molecular cloning and expression of the Physarum actin-fragmin kinase (AFK) reveals a novel type of protein kinase. (1996)

EICHINGER, L, SCHLEICHER, M, Vandekerckhove, Joël, Gettemans, Jan

Differential binding of ligands to bovine profilin isoforms. (1996)

Lambrechts, Anja, VERSCHELDE, JL, JONCKHEERE, V, GOETHALS, M, Vandekerckhove, Joël, Ampe, Christophe

Detailed quantitative analysis of the actin-binding site of the actin-sequestering protein thymosin beta 4. (1996)

VANTROYS, M, DEWITTE, D, GOETHALS, M, CARLIER, MF, Vandekerckhove, Joël, Ampe, Christophe

A two plasmid co-expression system in Escherichia coli for the production of virion-like reverse transcriptase of the human immunodeficiency virus type 1. (1996)

JONCKHEERE, H, DEVREESE, K, DEBYSER, Z, Vandekerckhove, Joël, BALZARINI, J, DESMYTER, J, ...

Further characterization of the peroxisomal 3-hydroxyacyl-CoA dehydrogenases from rat liver - Relationship between the different dehydrogenases and evidence that fatty acids and the C-27 bile acids di- and tri-hydroxycoprostanic acids are metabolized by separate multifunctional proteins. (1996)

DIEUAIDENOUBHANI, M, NOVIKOV, D, BAUMGART, E, VANHOOREN, JCT, FRANSEN, M, GOETHALS, M, ...

Molecular analysis of the Rhodobacter capsulatus chaperonin (groESL) operon: Purification and characterization of Cpn60. (1996)

HUBNER, P, DAME, G, SANDMEIER, U, Vandekerckhove, Joël, BEYER, P, TADROS, MH

A novel type of protein kinase phosphorylates actin in the actin-fragmin complex. (1996)

EICHINGER, L, BOMBLIES, L, Vandekerckhove, Joël, SCHLEICHER, M, Gettemans, Jan

Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide. (1996)

PILLOT, T, GOETHALS, M, Vanloo, Berlinda, TALUSSOT, C, BRASSEUR, R, Vandekerckhove, Joël, ...

In vivo phosphorylation of actin in Physarum polycephalum - Study of the substrate specificity of the actin-fragmin kinase. (1996)

DECORTE, V, Gettemans, Jan, WAELKENS, E, Vandekerckhove, Joël

The primary structure of a chondrichthyan protamine: A new apparent contradiction in protamine evolution. (1996)

SAPERAS, N, BUESA, C, ABIAN, J, Vandekerckhove, Joël, KASINSKY, HE, CHIVA, M

Evidence for an actin binding helix in gelsolin segment 2; Have homologous sequences in segments 1 and 2 of gelsolin evolved to divergent actin binding functions? (1996)

VANTROYS, M, DEWITTE, D, GOETHALS, M, Vandekerckhove, Joël, Ampe, Christophe

Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome. (1996)

BAUMGART, E, VANHOOREN, JCT, FRANSEN, M, MARYNEN, P, Puype, Magda, Vandekerckhove, Joël, ...

Human 2-D PAGE databases for proteome analysis in health and disease: http://biobase.dk/cgi-bin/celis. (1996)

CELIS, JE, GROMOV, P, OSTERGAARD, M, MADSEN, P, HONORE, B, DEJGAARD, K, ...

Mammalian peroxisomal acyl-CoA oxidases. III. Molecular cloning and further characterization of human branched chain acyl-CoA oxidase (1996)

BAUMGART, E, VANHOOREN, J, FRANSEN, M, MARYNEN, P, Puype, Magda, Vandekerckhove, Joël, ...

Cloning of two proteins representing different subfamilies of a novel type / transmembrane protein family involved in vesicular trafficking (1996)

BLUM, R, FEICK, P, Puype, Magda, Vandekerckhove, Joël, KLENGEL, R, NASTAINCZYK, W, ...

Tß4 Is not a simple G-actin sequestering protein and interacts with F-actin at high concentration. (1996)

CARLIER, MF, DIDRY, D, ERK, I, LEPAULT, J, Van Troys, Marleen, Vandekerckhove, Joël, ...

Fragmin, a microfilament regulatory protein from Physarum polycephalum, is phosphorylated by Casein Kinase II-type enzymes (1996)

De Corte, Veerle, Gettemans, Jan, DE VILLE, Y, WAELKENS, E, Vandekerckhove, Joël

Identification by sequence analysis of some critical (30kDa) proteins in aged beef (1996)

TSILONIS, O, VAZEOU,S, YIALOURIS, PP, Vandekerckhove, Joël, STOEVA, S, VOELTER, W, ...

Analysis of the catalytic site of the actin ADP-ribosylating Clostridium perfringens iota toxin (1996)

Van Damme, Jozef, JUNG, M, HOFMANN, F, JUST, I, Vandekerckhove, Joël, AKTORIES, K

The human keratinocyte two-dimensional gel protein database (update 1995): Mapping components of signal transduction pathways. (1995)

CELIS, JE, RASMUSSEN, HH, GROMOV, P, OLSEN, E, MADSEN, P, LEFFERS, H, ...

ADP-ribosyltransferase type-A from turkey erythrocytes modifies actin at Arg-95 and Arg-372. (1995)

JUST, I, SEHR, P, JUNG, M, VANDAMME, J, Puype, Magda, Vandekerckhove, Joël, ...

RHO-ADP-RIBOSYLATING EXOENZYME FROM BACILLUS-CEREUS - PURIFICATION, CHARACTERIZATION, AND IDENTIFICATION OF THE NAD-BINDING SITE. (1995)

JUST, I, SELZER, J, JUNG, M, VANDAMME, J, Vandekerckhove, Joël, AKTORIES, K

THE ACTIN-BINDING PROPERTIES OF THE PHYSARUM ACTIN-FRAGMIN COMPLEX - REGULATION OF CALCIUM, PHOSPHOLIPIDS, AND PHOSPHORYLATION. (1995)

Gettemans, Jan, DEVILLE, Y, WAELKENS, E, Vandekerckhove, Joël

SECRETION OF BIOLOGICALLY-ACTIVE MURINE INTERLEUKIN-2 BY LACTOCOCCUS-LACTIS SUBSP LACTIS. (1995)

Steidler, Lothar, WELLS, JM, RAEYMAEKERS, A, Vandekerckhove, Joël, Fiers, Walther, Remaut, Erik

TRYPSIN-MEDIATED SEMISYNTHESIS OF SALMON-CALCITONIN. (1995)

DAVEY, MW, ROMMELAERE, H, DEBOECK, S, GOETHALS, M, VANDAMME, J, Vandekerckhove, Joël

Localization of I-2-imidolazoline binding-sites on monoamine oxidases. (1995)

TESSON, F, LIMONBOULEZ, I, URBAN, P, Puype, Magda, Vandekerckhove, Joël, COUPRY, I, ...

An agarose-based gel-concentration system for microsequence and mass spectrometric characterization of proteins previously purified in polyacrylamide gels starting at low picomole levels. (1995)

RIDER, MH, Puype, Magda, VANDAMME, J, Gevaert, Kris, DEBOECK, S, DALAYER, J, ...

PURIFICATION AND CHARACTERIZATION OF BOVINE PROFILIN .2. ACTIN, POLY(L-PROLINE) AND INOSITOLPHOSPHOLIPID BINDING. (1995)

Lambrechts, Anja, VANDAMME, J, GOETHALS, M, Vandekerckhove, Joël, Ampe, Christophe

PURIFICATION, IMMUNOLOGICAL CHARACTERIZATION AND CDNA CLONING OF A 47-KDA GLYCOPROTEIN SECRETED BY CARROT SUSPENSION CELLS. (1995)

VANENGELEN, FA, DEJONG, AJ, MEIJER, EA, KUIL, CW, MEYBOOM, JK, DIRKSE, WG, ...

Conformational behaviour of a synthetic peptide of the C-terminus of villin that interacts with actin - an NMR, CD and simulated annealing study. (1995)

SIMENEL, C, ROSE, T, GOETHALS, M, Vandekerckhove, Joël, FRIEDERICH, E, LOUVARD, D, ...

Microfilament Dynamics - Regulation of Actin Polymerization by Actin-Fragmin Kinase and Phosphatases. (1995)

WAELKENS, E, Gettemans, Jan, DECORTE, V, DEVILLE, Y, GORIS, J, Vandekerckhove, Joël, ...

STUDIES ON THE ACTIVE-SITE STRUCTURE OF C3-LIKE EXOENZYMES - INVOLVEMENT OF GLUTAMIC-ACID IN CATALYSIS OF ADP-RIBOSYLATION. (1995)

AKTORIES, K, JUNG, M, BOHMER, J, FRITZ, G, Vandekerckhove, Joël, JUST, I

THE SPECIFIC NH2-TERMINAL SEQUENCE AC-EEED OF ALPHA-SMOOTH MUSCLE ACTIN PLAYS A ROLE IN POLYMERIZATION IN-VITRO AND IN-VIVO. (1995)

CHAPONNIER, C, GOETHALS, M, JANMEY, PA, GABBIANI, F, GABBIANI, G, Vandekerckhove, Joël

Carotene desaturation is linked to a respiratory redox pathway in Varcissus pseudonarcissus-chromoplast membranes - Involvement of a 23-kDa oxygen-evolving-complex-like protein. (1995)

NIEVELSTEIN, V, Vandekerckhove, Joël, TADROS, MH, LINTIG, JV, NITSCHKE, W, BEYER, P

Structural and functional characterization of Bovine profilin II (1995)

AMPE, C, Lambrechts, Anja, Van Damme, Jozef, GOETHALS, M, Vandekerckhove, Joël

Trypsin-mediated semisynthesis of salmon calcitonin (1995)

DAVEY, MW, Rommelaere, Heidi, De Boeck, Stefaan, GOETHALS, M, Van Damme, Jozef, Vandekerckhove, Joël

Purification and characterization of bovine profilin II. Actin, poly (L-proline) and inositolphospholipid binding (1995)

Lambrechts, Anja, Van Damme, Jozef, GOETHALS, M, Vandekerckhove, Joël, Ampe, Christophe

A 50-KDA PROTEIN PRESENT IN CONDITIONED MEDIUM OF COLO-16 CELLS STIMULATES CELL SPREADING AND MOTILITY, AND ACTIVATES TYROSINE PHOSPHORYLATION OF NEU/HER-2, IN HUMAN SK-BR-3 MAMMARY-CANCER CELLS. (1994)

DECORTE, V, DEPOTTER, C, VANDENBERGHE, D, VANLAEREBEKE, N, AZAM, M, ROELS, H, ...

The human keratinocyte two-dimensional protein database (update 1994) : towards an integrated approach to the study of cell proliferation, differentiation and skin-diseases. (1994)

CELIS, JE, RASMUSSEN, HH, OLSEN, E, MADSEN, P, LEFFERS, H, HONORE, B, ...

BETA-ACTIN SPECIFIC MONOCLONAL-ANTIBODY. (1994)

GIMONA, M, Vandekerckhove, Joël, GOETHALS, M, HERZOG, M, LANDO, Z, SMALL, JV

The residues Leu(Ile)475-Ile(Leu,Val, Ala)476, contained in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMPII to lysosomes. (1994)

SANDOVAL, IV, ARREDONDO, JJ, ALCALDE, J, NORIEGA, AG, Vandekerckhove, Joël, JIMENEZ, MA, ...

Production of enzymatically active-rat protein disulfide-isomerase in Escherichia-coli. (1994)

DESUTTER, K, HOSTENS, K, Vandekerckhove, Joël, Fiers, Walther

Molecular clotting, expression an characterization of PTPA, a protein that activates the tyrosyl phosphate activity of protein phosphatase 2A. (1994)

CAYLA, X, VANHOOF, C, BOSCH, M, WAELKENS, E, Vandekerckhove, Joël, PEETERS, B, ...

A novel cochaperonin that modulates the ATPases activity of cytoplasmic chaperonin. (1994)

GAO, Y, WALDEN, PD, LEWIS, SA, Ampe, Christophe, Rommelaere, Heidi, Vandekerckhove, Joël, ...

A 92-KDA HUMAN IMMUNOSTIMULATORY PROTEIN. (1994)

FONTAN, E, BRIEND, E, SAKLANIJUSFORGUES, H, DALAYER, J, Vandekerckhove, Joël, FAUVE, RM

Purification of a cortical complex containing 2 unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose. (1994)

MACHESKY, LM, ATKINSON, SJ, Ampe, Christophe, Vandekerckhove, Joël, POLLARD, TD

CLONING, EXPRESSION, AND IN-SITU LOCALIZATION OF RAT INTESTINAL CGMP-DEPENDENT PROTEIN-KINASE-II. (1994)

JARCHAU, T, HAUSLER, C, MARKERT, T, POHLER, D, Vandekerckhove, Joël, DEJONGE, HR, ...

INHIBITION OF THE DNA-BINDING ACTIVITY OF DROSOPHILA SUPPRESSOR OF HAIRLESS AND OF ITS HUMAN HOMOLOG, KBF2/RBP-J-KAPPA, BY DIRECT PROTEIN-PROTEIN INTERACTION WITH DROSOPHILA HAIRLESS. (1994)

BROU, C, LOGEAT, F, LECOURTOIS, M, Vandekerckhove, Joël, KOURILSKY, P, SCHWEISGUTH, F, ...

THE ROOT EPIDERMIS-SPECIFIC PEA GENE RH2 IS HOMOLOGOUS TO A PATHOGENESIS-RELATED GENE. (1994)

MYLONA, P, MOERMAN, M, YANG, WC, GLOUDEMANS, T, Vandekerckhove, Joël, VANKAMMEN, A, ...

Actin-actin binding protein interfaces (1994)

Ampe, Christophe, Vandekerckhove, Joël

ß-Acün specific monoclonal antibody (1994)

GIMONA, M, Vandekerckhove, Joël, GOETHALS, M, HERZOG, M, LANDO, Z, SMALL, JV

Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-JK, by direct protein-protein interaction with Drosophila hairless (1994)

BROU, C, LOGEAT, F, LECOURTOIS, M, Vandekerckhove, Joël, KOURILSKY, P, SCHWEISGUTH, F, ...

The human keratinocyte two-dimensional protein database (update 1994): toward an integrated approach to the study of cell proliferation, differentiation and skin diseases (1994)

ECELIS, J, RASMUSSEN, H, OLSE, E, MADSEN, P, LEFFERS, H, HONORE, B, ...

Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose (1994)

MACHESKY, L, ATKINSON, SJ, Ampe, Christophe, Vandekerckhove, Joël, POLLARD, TD

IDENTIFICATION OF 2 HUMAN-RHO GDP DISSOCIATION INHIBITOR PROTEINS WHOSE OVEREXPRESSION LEADS TO DISRUPTION OF THE ACTIN CYTOSKELETON. (1993)

LEFFERS, H, NIELSEN, MS, ANDERSEN, AH, HONORE, B, MADSEN, P, Vandekerckhove, Joël, ...

CLONING AND EXPRESSION OF A CDNA COVERING THE COMPLETE CODING REGION OF THE P-32 SUBUNIT OF HUMAN PRE-MESSENGER-RNA SPLICING FACTOR-SF2. (1993)

HONORE, B, MADSEN, P, RASMUSSEN, HH, Vandekerckhove, Joël, CELIS, JE, LEFFERS, H

THE HUMAN KERATINOCYTE 2-DIMENSIONAL GEL PROTEIN DATABASE - UPDATE 1993. (1993)

CELIS, JE, RASMUSSEN, HH, OLSEN, E, MADSEN, P, LEFFERS, H, HONORE, B, ...

Cloning and sequencing of rat liver cDNAs encoding the regulatory protein of glucokinase. (1993)

DETHEUX, M, Vandekerckhove, Joël, VANSCHAFTINGEN, E

HIGH-LEVEL EXPRESSION, PURIFICATION, AND RENATURATION OF RECOMBINANT MURINE INTERLEUKIN-2 FROM ESCHERICHIA-COLI. (1993)

Guisez, Yves, Demolder, Jan, Mertens, Nico, RAEYMAEKERS, A, PLAETINCK, G, ROBBENS, J, ...

THE ROLE OF ADHESIVE F107-FIMBRIAE AND OF SLT-IIV TOXIN IN THE PATHOGENESIS OF EDEMA DISEASE IN PIGS. (1993)

IMBERECHTS, H, DEGREVE, H, HERNALSTEENS, JP, SCHLICKER, C, BOUCHET, H, POHL, P, ...

IDENTIFICATION OF DROSOPHILA WING IMAGINAL DISC PROTEINS BY 2-DIMENSIONAL GEL ANALYSIS AND MICROSEQUENCING. (1993)

SANTAREN, JF, VANDAMME, J, Puype, Magda, Vandekerckhove, Joël, GARCIABELLIDO, A

Purification and partial amino-acid-sequence of the actin-fragmin kinase from Physarum-polycephalum. (1993)

Gettemans, Jan, DEVILLE, Y, Vandekerckhove, Joël, WAELKENS, E

Molecular cloning, sequence analysis and expression of the gene for catalase-peroxidase (CPEA) from the photosynthetic bacterium Rhodobacter capsulatus B 10. (1993)

FORKL, H, Vandekerckhove, Joël, DREWS, G, TADROS, MH

STUDIES OF THE ROLE OF THE PROPEPTIDES OF THE ARABIDOPSIS-THALIANA 2S ALBUMIN. (1993)

DHONDT, K, VANDAMME, J, VANDENBOSSCHE, C, LEEJEERAJUMNEAN, S, DERYCKE, R, DERKSEN, J, ...

Molecular cloning and expression of the transformation sensitive epithelial marker stratifin. A member of a protein family that has been involved in the protein kinase c signalling pathway. (1993)

LEFFERS, H, MADSEN, P, RASMUSSEN, HH, HONORE, B, ANDERSEN, AH, WALBUM, E, ...

PRIMARY STRUCTURE OF AND STUDIES ON ACANTHAMOEBA-ACTOPHORIN. (1993)

QUIRK, S, MACIVER, SK, Ampe, Christophe, DOBERSTEIN, SK, KAISER, DA, VANDAMME, J, ...

SYNTHESIS OF DEXTRAN DERIVATIVES WITH THIOL-SPECIFIC REACTIVE GROUPS FOR THE PREPARATION OF DEXTRAN PROTEIN CONJUGATES. (1993)

Herman, Sabine, PERSIJN, G, Vandekerckhove, Joël, Schacht, Etienne

AN ASPARTIC PROTEINASE PRESENT IN SEEDS CLEAVES ARABIDOPSIS-2-S ALBUMIN PRECURSORS IN-VITRO. (1993)

DHONDT, K, BOSCH, D, VANDAMME, J, GOETHALS, M, Vandekerckhove, Joël, KREBBERS, E

NAD-binding site of the C3-like ADP-ribosyltransferase from Clostridium limosum. (1993)

JUNG, M, JUST, I, VANDAMME, J, Vandekerckhove, Joël, AKTORIES, K

EUKARYOTIC CYTOSOLIC CHAPERONIN CONTAINS T-COMPLEX POLYPEPTIDE-1 AND 7 RELATED SUBUNITS. (1993)

ROMMELAERE, H, VANTROYS, M, GAO, YJ, MELKI, R, COWAN, NJ, Vandekerckhove, Joël, ...

Human cellular protein patterns and their link to genome DNA mapping and sequencing data : towards an integrated approach to the study of gene expression (1993)

CELIS, JE, RASMUSSEN, HH, LEFFERS, H, MADSEN, P, HONORE, B, DEJGAARD, K, ...

The human keratinocyte two-dimensional gel protein database: Update 1993 (1993)

CELIS, JE, RASMUSSEN, HH, OLSEN, E, MADSEN, P, LEFFERS, H, HONORE, B, ...

Studies on the role of the processed regions of the Arabidopsis thaliana 2S albumin. (1993)

D'Hondt, Kathleen, Van Damme, Jozef, LEEJEERAJUMNEAN, S, DE RYCKE, R, DERKSEN, J, ...

Routine amino acid sequencing on 2D-gel separated proteins: a protein elution and concentration gel system (1993)

Vandekerckhove, Joël, RIDER, M, RASMUSSEN, HH, De Boeck, Stefaan, Puype, Magda, Van Damme, Jozef, ...

Actins (1993)

Vandekerckhove, Joël

The human keratinocyte two-dimensional gel protein database : Update 1993 (1993)

CELIS, JE, RASMUSSEN, HH, OLSE, E, MADSEN, P, LEFFERS, H, HONORE, B, ...

Cloning and expression of a cDNA covering the complete coding region of the P32 subunit of human pre-mRNA splicing factor SF2 (1993)

HONORE, B, MADSEN, P, RASMUSSEN, HH, Vandekerckhove, Joël, CELIS, JE, LEFFERS, H

Identification of two human rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton (1993)

LEFFERS, H, NIELSEN, HS, ANDERSEN, AH, HONORE, B, MADSEN, P, Vandekerckhove, Joël, ...

Eukaryotic cytosolic chaperonin contains t-complex polypeptide 1 and seven related subunits (1993)

ROMMELAERE, M, VAN TROYS, H, GAO, Y, MELKI, R, COWAN, NJ, Vandekerckhove, Joël, ...

THE HUMAN KERATINOCYTE 2-DIMENSIONAL GEL PROTEIN DATABASE (UPDATE 1992) - TOWARDS AN INTEGRATED APPROACH TO THE STUDY OF CELL-PROLIFERATION, DIFFERENTIATION AND SKIN DISEASES. (1992)

CELIS, JE, RASMUSSEN, HH, MADSEN, P, LEFFERS, H, HONORE, B, DEJGAARD, K, ...

MICROSEQUENCES OF 145 PROTEINS RECORDED IN THE 2-DIMENSIONAL GEL PROTEIN DATABASE OF NORMAL HUMAN EPIDERMAL-KERATINOCYTES. (1992)

RASMUSSEN, HH, VANDAMME, J, Puype, Magda, GESSER, B, CELIS, JE, Vandekerckhove, Joël

An additional exon in the human vinculin gene specifically encodes meta-vinculin-specific difference peptide. Cross-species comparison reveals variable and conserved motifs in the meta-vinculin insert. (1992)

KOTELIANSKY, VE, OGRYZKO, EP, ZHIDKOVA, NI, WELLER, PA, CRITCHLEY, DR, Vancompernolle, Katia, ...

Molecular-Cloning and Expression of a Transformation-sensitive Human Protein Containing the TPR Motif and Sharing Identity to the Stress-inducible Yeast Protein, STI1. (1992)

HONORE, B, LEFFERS, H, MADSEN, P, RASMUSSEN, HH, Vandekerckhove, Joël, CELIS, JE

A CARROT SOMATIC EMBRYO MUTANT IS RESCUED BY CHITINASE. (1992)

DEJONG, AJ, CORDEWENER, J, LOSCHIAVO, F, TERZI, M, Vandekerckhove, Joël, VANKAMMEN, A, ...

Purification and Characterization of an ADP-ribosyltransferase Produced by Clostridium-limosum. (1992)

JUST, I, MOHR, C, SCHALLEHN, G, MENARD, L, DIDSBURY, JR, Vandekerckhove, Joël, ...

Structure and Function of Actin. (1992)

KABSCH, W, Vandekerckhove, Joël

An actin-binding site containing a conserved motif of charged amino acid residues is essential for the morphogenic effect of villin. (1992)

FRIEDERICH, E, VANCOMPERNOLLE, K, HUET, C, GOETHALS, M, FINIDORI, J, Vandekerckhove, Joël, ...

THE 2 FORMS OF BOVINE HEART 6-PHOSPHOFRUCTO-2-KINASE FRUCTOSE-2,6-BISPHOSPHATASE RESULT FROM ALTERNATIVE SPLICING. (1992)

RIDER, MH, VANDAMME, J, LEBEAU, E, VERTOMMEN, D, VIDAL, H, ROUSSEAU, GG, ...

Physarum aclin is phosphorylated as the actin-fragmin complex at residues Thr203 and Thr202 by a specific 80kDa kinase. (1992)

Gettemans, Jan, DEVILLE, Y, Vandekerckhove, Joël, WAELKENS, E

EVIDENCE FOR NEW PHOSPHORYLATION SITES FOR PROTEIN-KINASE-C AND CYCLIC AMP-DEPENDENT PROTEIN-KINASE IN BOVINE HEART 6-PHOSPHOFRUCTO-2-KINASE FRUCTOSE-2,6-BISPHOSPHATASE. (1992)

RIDER, MH, VANDAMME, J, VERTOMMEN, D, MICHEL, A, Vandekerckhove, Joël, HUE, L

AMPHIBIAN INTESTINAL VILLIN - ISOLATION AND EXPRESSION DURING EMBRYONIC AND LARVAL DEVELOPMENT. (1992)

HEUSSER, S, COLIN, S, FIGIEL, A, HUET, C, KELLER, JM, PORNET, P, ...

G-ACTIN TO F-ACTIN MODULATION BY A SINGLE AMINO-ACID SUBSTITUTION IN THE ACTIN BINDING-SITE OF ACTOBINDIN AND THYMOSIN BETA-4. (1992)

VANCOMPERNOLLE, K, GOETHALS, M, HUET, C, LOUVARD, D, Vandekerckhove, Joël

Identification of histidine-rich, abscisic acid-responsive rice (Ozyza sativa) protein. (1992)

Moons, Ann, Vandekerckhove, Joël, Villarroel-Mandiola, Raimundo, Van Montagu, Marc, Van Der Straeten, Dominique, DEKEYSER, R

A comprehensive two-dimensional gel protein database of noncultured unfrac-tionated normal human epidermal keratinocytes : Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases (1992)

CELIS, J, MADSEN, P, RASMUSSEN, H, LEFFERS, H, HONORE, B, GESSER, B, ...

The two forms of bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase result from alternative splicing (1992)

RIDER, M, Van Damme, Jozef, LEBEAU, E, VERTOMMEN, D, VIDAL, H, ROUSSEAU, G, ...

Structural relationships of actin-binding proteins (1992)

Vandekerckhove, Joël, Vancompernolle, Katia

The human keratinocyte two-dimensional gel protein database (update 1992) : Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases (1992)

CELIS, JE, RASMUSSEN, HH, MADSEN, P, LEFFERS, H, HONORE, B, DEJGAARD, K, ...

Expression of modified seed storage proteins in transgenic plants (1992)

KREBBERS, E, VAN ROMPAEY, J, Vandekerckhove, Joël

Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes (1992)

RASMUSSEN, HH, Van Damme, Jozef, Puype, Magda, GESSER, B, CELIS, JE, Vandekerckhove, Joël

Evidence for new phosphorylation sites for protein kinase C and cyclic AMP-dependent protein kinase in bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (1992)

RIDER, MH, Van Damme, Jozef, VERTOMMEN, D, MICHEL, A, Vandekerckhove, Joël, HUE, L

G- to F-actin modulation by a single amino acid substitution in the actin binding site of actobindin and thymosine 64 (1992)

Vancompernolle, Katia, GOETHALS, M, HUET, C, LOUVARD, D, Vandekerckhove, Joël

CHARACTERIZATION OF F107 FIMBRIAE OF ESCHERICHIA-COLI 107/86, WHICH CAUSES EDEMA DISEASE IN PIGS, AND NUCLEOTIDE-SEQUENCE OF THE F107 MAJOR FIMBRIAL SUBUNIT GENE, FEDA (1992)

IMBERECHTS, H, DEGREVE, H, SCHLICKER, C, BOUCHET, H, POHL, P, CHARLIER, G, ...

THE MASTER 2-DIMENSIONAL GEL DATABASE OF HUMAN AMA CELL-PROTEINS - TOWARDS LINKING PROTEIN AND GENOME SEQUENCE AND MAPPING INFORMATION (UPDATE 1991). (1991)

CELIS, JE, LEFFERS, H, RASMUSSEN, HH, MADSEN, P, HONORE, B, GESSER, B, ...

A COMPREHENSIVE 2-DIMENSIONAL GEL PROTEIN DATABASE OF NONCULTURED UNFRACTIONATED NORMAL HUMAN EPIDERMAL-KERATINOCYTES - TOWARDS AN INTEGRATED APPROACH TO THE STUDY OF CELL-PROLIFERATION, DIFFERENTIATION AND SKIN DISEASES. (1991)

CELIS, JE, MADSEN, P, RASMUSSEN, HH, LEFFERS, H, HONORE, B, GESSER, B, ...

MICROSEQUENCING OF PROTEINS RECORDED IN HUMAN 2-DIMENSIONAL GEL PROTEIN DATABASES. (1991)

RASMUSSEN, HH, VANDAMME, J, Puype, Magda, GESSER, B, CELIS, JE, Vandekerckhove, Joël

Production and purification of recombinant human interleukin-6 secreted by the yeast Saccharomyces cerevisiae (1991)

Guisez, Yves, TISON, B, Vandekerckhove, Joël, Demolder, Jan, Bauw, Gino, Haegeman, Guy, ...

Neuronal protein gene product 9.5 (IEF SSP 6104) is expressed in cultured human MRC-5 fibroblast of normal origin and is strongly down-regulated in their SV40 transformed counterparts (1991)

HONORE, B, RASMUSSEN, H, Vandekerckhove, Joël, CELIS, J

Protein-electroblotting and microsequencing in establishing integrated human protein databases (1991)

RASMUSSEN, H, Van Damme, Jozef, Bauw, Gino, Puype, Magda, GESSER, B, CELIS, J, ...

The master two-dimensional gel database of human AMA cell proteins : Towards linking protein and genome sequence and mapping information (Update 1991) (1991)

CELIS, J, LEFFERS, H, RASMUSSEN, H, MADSEN, P, HONORE, B, GESSER, B, ...

Microsequencing of proteins recorded in human two-dimensional gel protein databases (1991)

RASMUSSEN, H, Van Damme, Jozef, Puype, Magda, GESSER, B, CELIS, J, Vandekerckhove, Joël

The interfaces of actin and Acanthamoeba actobindin (1991)

Vancompernolle, Katia, Vandekerckhove, Joël, BUBB, M, KORN, E

Cloning, sequencing and expression of a cDNA encoding rat LIMP II, a novel 74kDa lysosomal membrane protein related to the surface adhesion protein CD36. (1991)

VEGA, M, SEGUI-REAL, B, GARCIA, J, CALES, C, RODRIGUEZ, F, Vandekerckhove, Joël, ...

Evidence for the identy of human scatter factor and human hepatocyte growth factor. (1991)

WEIDNER, K, ARAKAKI, N, HARTMANN, G, Vandekerckhove, Joël, WEINGART, S, RIEDER, H, ...

A distal dimerization domain is essential for DNA-binding by the atypical HNF1 homeodomain (1990)

Chouard, Tanguy, Blumenfeld, Marta, Bach, Ingolf, Vandekerckhove, Joël, Cereghini, Silvia, Yaniv, Moshe

Hepatic Nuclear Factor 1 (HNF1, also referred to as LFB1, HP1 or APF) is a liver-specific transcnption factor required for the expression of many hepatocyte specific genes. We report here the...

ISOLATION AND NUCLEOTIDE-SEQUENCE OF THE F17-A GENE ENCODING THE STRUCTURAL PROTEIN OF THE F-17 FIMBRIAE IN BOVINE ENTERO-TOXIGENIC ESCHERICHIA-COLI (1988)

LINTERMANS, P, POHL, P, DEBOECK, F, BERTELS, A, SCHLICKER, C, Vandekerckhove, Joël, ...

Molecular characterization of the human peroxisomal branchedchain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome

Baumgart, Eveline, Vanhooren, Johannes C. T., Fransen, Mark, Marynen, Peter, Puype, Magda, Vandekerckhove, Joël, ...

Peroxisomes in human liver contain two distinct acyl-CoA oxidases with different substrate specificities: (i) palmitoyl-CoA oxidase, oxidizing very long straight-chain fatty acids and eicosanoids,...

Partial purification and identification of GDP-mannose 3",5"-epimerase of Arabidopsis thaliana, a key enzyme of the plant vitamin C pathway

Wolucka, Beata A., Persiau, Geert, Van Doorsselaere, Jan, Davey, Mark W., Demol, Hans, Vandekerckhove, Joël, ...

The first step in the biosynthetic pathway of vitamin C in plants is the formation, at the level of sugar nucleotide, of l-galactosyl residues, catalyzed by a largely unknown GDP-d-mannose...

Profilin II Is Alternatively Spliced, Resulting in Profilin Isoforms That Are Differentially Expressed and Have Distinct Biochemical Properties

Lambrechts, Anja, Braun, Attila, Jonckheere, Veronique, Aszodi, Attila, Lanier, Lorene M., Robbens, Johan, ...

We deduced the structure of the mouse profilin II gene. It contains five exons that can generate four different transcripts by alternative splicing. Two transcripts encode different profilin II...

Proteomic Analysis of Arabidopsis Seed Germination and Priming1

Gallardo, Karine, Job, Claudette, Groot, Steven P.C., Puype, Magda, Demol, Hans, Vandekerckhove, Joël, ...

To better understand seed germination, a complex developmental process, we developed a proteome analysis of the model plant Arabidopsis for which complete genome sequence is now available. Among...

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE

Van Herreweghe, Franky, Mao, Jianqiang, Chaplen, Frank W. R., Grooten, Johan, Gevaert, Kris, Vandekerckhove, Joël, ...

Tumor necrosis factor (TNF)-induced cell death in the fibrosarcoma cell line L929 is a caspase-independent process that is characterized by increased production of reactive oxygen species (ROS) in...

Gelsolin-induced epithelial cell invasion is dependent on Ras–Rac signaling

De Corte, Veerle, Bruyneel, Erik, Boucherie, Ciska, Mareel, Marc, Vandekerckhove, Joël, Gettemans, Jan

Gelsolin is a widely distributed actin binding protein involved in controlling cell morphology, motility, signaling and apoptosis. The role of gelsolin in tumor progression, however, remains poorly...

The expression, processing and localization of polymorphic membrane proteins in Chlamydia pneumoniae strain CWL029

Vandahl, Brian Berg, Pedersen, Anna Sofie, Gevaert, Kris, Holm, Arne, Vandekerckhove, Joël, Christiansen, Gunna, ...

Proteomics of Arabidopsis Seed Germination. A Comparative Study of Wild-Type and Gibberellin-Deficient Seeds1

Gallardo, Karine, Job, Claudette, Groot, Steven P.C., Puype, Magda, Demol, Hans, Vandekerckhove, Joël, ...

We examined the role of gibberellins (GAs) in germination of Arabidopsis seeds by a proteomic approach. For that purpose, we used two systems. The first system consisted of seeds of the GA-deficient...

Involvement of Sialoadhesin in Entry of Porcine Reproductive and Respiratory Syndrome Virus into Porcine Alveolar Macrophages

Vanderheijden, Nathalie, Delputte, Peter L., Favoreel, Herman W., Vandekerckhove, Joël, Van Damme, Jozef, Van Woensel, Peter A., ...

Porcine reproductive and respiratory syndrome virus (PRRSV) shows a very restricted tropism for cells of the monocyte/macrophage lineage. It enters cells via receptor-mediated endocytosis. A...

Heteromeric MAPPIT: a novel strategy to study modification-dependent protein–protein interactions in mammalian cells

Lemmens, Irma, Eyckerman, Sven, Zabeau, Lennart, Catteeuw, Dominiek, Vertenten, Els, Verschueren, Kristin, ...

We recently reported a two-hybrid trap for detecting protein–protein interactions in intact mammalian cells (MAPPIT). The bait protein was fused to a STAT recruitment-deficient, homodimeric...

Proteomics of Medicago truncatula Seed Development Establishes the Time Frame of Diverse Metabolic Processes Related to Reserve Accumulation1

Gallardo, Karine, Le Signor, Christine, Vandekerckhove, Joël, Thompson, Richard D., Burstin, Judith

We utilized a proteomic approach to investigate seed development in Medicago truncatula, cv Jemalong, line J5 at specific stages of seed filling corresponding to the acquisition of germination...

β-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility

Oliveira, Maria José, Van Damme, Jozef, Lauwaet, Tineke, De Corte, Veerle, De Bruyne, Georges, Verschraegen, Gerda, ...

In colon cancer, enteric bacteria and dietary factors are major determinants of the microenvironment but their effect on cellular invasion is not known. We therefore incubated human HCT-8/E11 colon...

The Effect of α-Amanitin on the Arabidopsis Seed Proteome Highlights the Distinct Roles of Stored and Neosynthesized mRNAs during Germination1

Rajjou, Loïc, Gallardo, Karine, Debeaujon, Isabelle, Vandekerckhove, Joël, Job, Claudette, Job, Dominique

To investigate the role of stored and neosynthesized mRNAs in seed germination, we examined the effect of α-amanitin, a transcriptional inhibitor targeting RNA polymerase II, on the germination of...

TetraThymosinβ Is Required for Actin Dynamics in Caenorhabditis elegans and Acts via Functionally Different Actin-binding Repeats

Van Troys, Marleen, Ono, Kanako, Dewitte, Daisy, Jonckheere, Veronique, De Ruyck, Natalie, Vandekerckhove, Joël, ...

Generating specific actin structures via controlled actin polymerization is a prerequisite for eukaryote development and reproduction. We here report on an essential Caenorhabditis elegans protein...

A method for rapidly screening functionality of actin mutants and tagged actins

Rommelaere, Heidi, Waterschoot, Davy, Neirynck, Katrien, Vandekerckhove, Joël, Ampe, Christophe

Recombinant production and biochemical analysis of actin mutants has been hampered by the fact that actin has an absolute requirement for the eukaryotic chaperone CCT to reach its native state. We...

Expression and Processing of an Arabidopsis 2S Albumin in Transgenic Tobacco 1

De Clercq, Ann, Vandewiele, Martine, De Rycke, Riet, Van Damme, Jozef, Van Montagu, Marc, Krebbers, Enno, ...

2S albumin seed storage proteins undergo a complex series of posttranslational proteolytic cleavages. In order to determine if this process is correctly carried out in transgenic plants, the gene...

Stable Accumulation of Modified 2S Albumin Seed Storage Proteins with Higher Methionine Contents in Transgenic Plants 1

De Clercq, Ann, Vandewiele, Martine, Van Damme, Jozef, Guerche, Philippe, Van Montagu, Marc, Vandekerckhove, Joël, ...

We present the results of two sets of experiments designed to express high methionine proteins in transgenic seeds in three different plant species. In the first approach, two chimeric genes were...

Cell_motility: a cross-platform, open source application for the study of cell motion paths

Martens, Lennart, Monsieur, Geert, Ampe, Christophe, Gevaert, Kris, Vandekerckhove, Joël

Molecular characterization of the human peroxisomal branchedchain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome

Baumgart, Eveline, Vanhooren, Johannes C. T., Fransen, Mark, Marynen, Peter, Puype, Magda, Vandekerckhove, Joël, ...

Peroxisomes in human liver contain two distinct acyl-CoA oxidases with different substrate specificities: (i) palmitoyl-CoA oxidase, oxidizing very long straight-chain fatty acids and eicosanoids,...

Partial purification and identification of GDP-mannose 3",5"-epimerase of Arabidopsis thaliana, a key enzyme of the plant vitamin C pathway

Wolucka, Beata A., Persiau, Geert, Van Doorsselaere, Jan, Davey, Mark W., Demol, Hans, Vandekerckhove, Joël, ...

The first step in the biosynthetic pathway of vitamin C in plants is the formation, at the level of sugar nucleotide, of l-galactosyl residues, catalyzed by a largely unknown GDP-d-mannose...

Profilin II Is Alternatively Spliced, Resulting in Profilin Isoforms That Are Differentially Expressed and Have Distinct Biochemical Properties

Lambrechts, Anja, Braun, Attila, Jonckheere, Veronique, Aszodi, Attila, Lanier, Lorene M., Robbens, Johan, ...

We deduced the structure of the mouse profilin II gene. It contains five exons that can generate four different transcripts by alternative splicing. Two transcripts encode different profilin II...

Proteomic Analysis of Arabidopsis Seed Germination and Priming1

Gallardo, Karine, Job, Claudette, Groot, Steven P.C., Puype, Magda, Demol, Hans, Vandekerckhove, Joël, ...

To better understand seed germination, a complex developmental process, we developed a proteome analysis of the model plant Arabidopsis for which complete genome sequence is now available. Among...

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE

Van Herreweghe, Franky, Mao, Jianqiang, Chaplen, Frank W. R., Grooten, Johan, Gevaert, Kris, Vandekerckhove, Joël, ...

Tumor necrosis factor (TNF)-induced cell death in the fibrosarcoma cell line L929 is a caspase-independent process that is characterized by increased production of reactive oxygen species (ROS) in...

Gelsolin-induced epithelial cell invasion is dependent on Ras–Rac signaling

De Corte, Veerle, Bruyneel, Erik, Boucherie, Ciska, Mareel, Marc, Vandekerckhove, Joël, Gettemans, Jan

Gelsolin is a widely distributed actin binding protein involved in controlling cell morphology, motility, signaling and apoptosis. The role of gelsolin in tumor progression, however, remains poorly...

The expression, processing and localization of polymorphic membrane proteins in Chlamydia pneumoniae strain CWL029

Vandahl, Brian Berg, Pedersen, Anna Sofie, Gevaert, Kris, Holm, Arne, Vandekerckhove, Joël, Christiansen, Gunna, ...

Proteomics of Arabidopsis Seed Germination. A Comparative Study of Wild-Type and Gibberellin-Deficient Seeds1

Gallardo, Karine, Job, Claudette, Groot, Steven P.C., Puype, Magda, Demol, Hans, Vandekerckhove, Joël, ...

We examined the role of gibberellins (GAs) in germination of Arabidopsis seeds by a proteomic approach. For that purpose, we used two systems. The first system consisted of seeds of the GA-deficient...

Involvement of Sialoadhesin in Entry of Porcine Reproductive and Respiratory Syndrome Virus into Porcine Alveolar Macrophages

Vanderheijden, Nathalie, Delputte, Peter L., Favoreel, Herman W., Vandekerckhove, Joël, Van Damme, Jozef, Van Woensel, Peter A., ...

Porcine reproductive and respiratory syndrome virus (PRRSV) shows a very restricted tropism for cells of the monocyte/macrophage lineage. It enters cells via receptor-mediated endocytosis. A...

Heteromeric MAPPIT: a novel strategy to study modification-dependent protein–protein interactions in mammalian cells

Lemmens, Irma, Eyckerman, Sven, Zabeau, Lennart, Catteeuw, Dominiek, Vertenten, Els, Verschueren, Kristin, ...

We recently reported a two-hybrid trap for detecting protein–protein interactions in intact mammalian cells (MAPPIT). The bait protein was fused to a STAT recruitment-deficient, homodimeric...

Proteomics of Medicago truncatula Seed Development Establishes the Time Frame of Diverse Metabolic Processes Related to Reserve Accumulation1

Gallardo, Karine, Le Signor, Christine, Vandekerckhove, Joël, Thompson, Richard D., Burstin, Judith

We utilized a proteomic approach to investigate seed development in Medicago truncatula, cv Jemalong, line J5 at specific stages of seed filling corresponding to the acquisition of germination...

β-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility

Oliveira, Maria José, Van Damme, Jozef, Lauwaet, Tineke, De Corte, Veerle, De Bruyne, Georges, Verschraegen, Gerda, ...

In colon cancer, enteric bacteria and dietary factors are major determinants of the microenvironment but their effect on cellular invasion is not known. We therefore incubated human HCT-8/E11 colon...

The Effect of α-Amanitin on the Arabidopsis Seed Proteome Highlights the Distinct Roles of Stored and Neosynthesized mRNAs during Germination1

Rajjou, Loïc, Gallardo, Karine, Debeaujon, Isabelle, Vandekerckhove, Joël, Job, Claudette, Job, Dominique

To investigate the role of stored and neosynthesized mRNAs in seed germination, we examined the effect of α-amanitin, a transcriptional inhibitor targeting RNA polymerase II, on the germination of...

TetraThymosinβ Is Required for Actin Dynamics in Caenorhabditis elegans and Acts via Functionally Different Actin-binding Repeats

Van Troys, Marleen, Ono, Kanako, Dewitte, Daisy, Jonckheere, Veronique, De Ruyck, Natalie, Vandekerckhove, Joël, ...

Generating specific actin structures via controlled actin polymerization is a prerequisite for eukaryote development and reproduction. We here report on an essential Caenorhabditis elegans protein...

A method for rapidly screening functionality of actin mutants and tagged actins

Rommelaere, Heidi, Waterschoot, Davy, Neirynck, Katrien, Vandekerckhove, Joël, Ampe, Christophe

Recombinant production and biochemical analysis of actin mutants has been hampered by the fact that actin has an absolute requirement for the eukaryotic chaperone CCT to reach its native state. We...

Expression and Processing of an Arabidopsis 2S Albumin in Transgenic Tobacco 1

De Clercq, Ann, Vandewiele, Martine, De Rycke, Riet, Van Damme, Jozef, Van Montagu, Marc, Krebbers, Enno, ...

2S albumin seed storage proteins undergo a complex series of posttranslational proteolytic cleavages. In order to determine if this process is correctly carried out in transgenic plants, the gene...

Stable Accumulation of Modified 2S Albumin Seed Storage Proteins with Higher Methionine Contents in Transgenic Plants 1

De Clercq, Ann, Vandewiele, Martine, Van Damme, Jozef, Guerche, Philippe, Van Montagu, Marc, Vandekerckhove, Joël, ...

We present the results of two sets of experiments designed to express high methionine proteins in transgenic seeds in three different plant species. In the first approach, two chimeric genes were...

Cell_motility: a cross-platform, open source application for the study of cell motion paths

Martens, Lennart, Monsieur, Geert, Ampe, Christophe, Gevaert, Kris, Vandekerckhove, Joël

The C-terminus of CIS defines its interaction pattern

Lavens, Delphine, Ulrichts, Peter, Catteeuw, Dominiek, Gevaert, Kris, Vandekerckhove, Joël, Peelman, Frank, ...

Proteins of the SOCS (suppressors of cytokine signalling) family are characterized by a conserved modular structure with pre-SH2 (Src homology 2), SH2 and SOCS-box domains. Several members, including...

Tumour necrosis factor induces phosphorylation primarily of the nitric-oxide-responsive form of glyoxalase I

DeHemptinne, Virginie, Rondas, Dieter, Vandekerckhove, Joël, Vancompernolle, Katia

We have previously shown that TNF (tumour necrosis factor) induces phosphorylation of GLO1 (glyoxalase I), which is required for cell death in L929 cells. In the present paper, we show that the...

A Mediator Role For Metallothionein in Tumor Necrosis Factor–induced Lethal Shock

Waelput, Wim, Broekaert, Daniël, Vandekerckhove, Joël, Brouckaert, Peter, Tavernier, Jan, Libert, Claude

Tumor necrosis factor (TNF) is a proinflammatory cytokine, which is centrally involved in several inflammatory disorders. Administration of TNF leads to a potentially lethal systemic inflammatory...

HyperISGylation of Old World Monkey ISG15 in Human Cells

Pattyn, Els, Verhee, Annick, Uyttendaele, Isabel, Piessevaux, Julie, Timmerman, Evy, Gevaert, Kris, ...

Actin.

Ampe, Christophe, Vandekerckhove, Joël

Assaying binding and covalent modifications of cytoskeletal proteins

Ampe, Christophe, Vandekerckhove, Joël

Aspartic proteases in the Brassicaceae Arabidopsis Thaliana and Brassica napus. Plant Mol. BioL 33, 187-192 (1997).

D'Hondt, Kathleen, STACK, S, GUTTERIDGE, S, Vandekerckhove, Joël, KREBBERS, E

The presequence of yeast pAPl folds into different helical conformations to mediate targeting and translocation of the protein through the vacuolar membrane. J. Mol. Biol. 267, 1124-1138 (1997).

MARTINEZ, E, JIMENEZ, MA, SEGUI-REAL, B, Vandekerckhove, Joël, SANDOVAL, I

Purification, characterization and molecular analysis of the Rhodobacter capsulatus chaperone DNAK. Gene. 192, 251-259(1997).

NICKEL, CM, Vandekerckhove, Joël, BEYER, P, JADROS, MN

Communications from the 11 * International Conference on Methods in Protein Structure Analysis. Special Issue Editors. J.Prot. Chem. 16(1997).

Vandekerckhove, Joël

Internal amio acid sequencing of proteins recovered from one- or two-dimensonal gels. Cell Biology. A Laboratory Handbook, 2nd Edition, Acad. Press, vol. 4 (1998).

Vandekerckhove, Joël, RASMUSSEN, HH

Contribution of apo A II and LCAT oblique peptides to HDL metabolism. Atherosclerosis 11,1155-1160 (1998).

Vanloo, Berlinda, PEREZ-MENDEZ, O, LAMBERT, G, TAVERNIER, I, Vandekerckhove, Joël, BRASSEUR, R, ...

Phenotypes induced by NM causing α-skeletal muscle actin mutants in fibroblasts, Sol 8 myoblasts and myotubes

Vandamme, Drieke, Lambert, Ellen, Waterschoot, Davy, Tondeleir, Davina, Vandekerckhove, Joël, Machesky, Laura M, ...

A review of COFRADIC techniques targeting protein N-terminal acetylation

Van Damme, Petra, Van Damme, Jozef, Demol, Hans, Staes, An, Vandekerckhove, Joël, Gevaert, Kris

Acetylation of nascent protein Nα-termini is a common modification among archae and eukaryotes and can influence the structure and function of target proteins. This modification has been studied on...

Structure of granzyme C reveals an unusual mechanism of protease autoinhibition

Kaiserman, Dion, Buckle, Ashley M., Van Damme, Petra, Irving, James A., Law, Ruby H. P., Matthews, Antony Y., ...

Proteases act in important homeostatic pathways and are tightly regulated. Here, we report an unusual structural mechanism of regulation observed by the 2.5-Å X-ray crystal structure of the serine...

Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster

Goetze, Sandra, Qeli, Ermir, Mosimann, Christian, Staes, An, Gerrits, Bertran, Roschitzki, Bernd, ...

A new study reveals a functional rule for N-terminal acetylation in higher eukaryotes called the (X)PX rule and describes a generic method that prevents this modification to allow the study of...

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

Arnesen, Thomas, Van Damme, Petra, Polevoda, Bogdan, Helsens, Kenny, Evjenth, Rune, Colaert, Niklaas, ...

Nα-terminal acetylation is one of the most common protein modifications in eukaryotes. The COmbined FRActional DIagonal Chromatography (COFRADIC) proteomics technology that can be specifically used...