Joe Gray

A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease (2009)

Gray, Joe, Chattopadhyay, Dipankar, Beale, Gary S, Patman, Gillian L, Miele, Luca, King, Barry P, ...

Abstract Background Non-alcoholic fatty liver disease (NAFLD) has a prevalence of over 20% in Western societies. Affected individuals are at risk of developing both cirrhosis and hepatocellular...

Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature (2008)

Tutt, Andrew, Wang, Alice, Rowland, Charles, Gillett, Cheryl, Lau, Kit, Chew, Karen, ...

Abstract Background Given the large number of genes purported to be prognostic for breast cancer, it would be optimal if the genes identified are not confounded by the continuously changing systemic...

AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease (2008)

Beale, Gary, Chattopadhyay, Dipankar, Gray, Joe, Stewart, Stephen, Hudson, Mark, Day, Christopher, ...

Abstract Background The incidence and mortality of hepatocellular cancer (HCC) complicating alcoholic and non-alcoholic fatty liver diseases (ALD and NAFLD) is rising in western societies. Despite...

America (2008)

James G. Conley, Brian Moran, Joe Gray

Engineering with Computers manuscript No. (will be inserted by the editor) A simulation-based design paradigm for complex cast components integrating damage tolerance assessment, casting process and...

Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities (2008)

Press, Joshua Z, De Luca, Alessandro, Boyd, Niki, Young, Sean, Troussard, Armelle, Ridge, Yolanda, ...

Background Subclassification of ovarian carcinomas can be used to guide treatment and determine prognosis. Germline and somatic mutations, loss of heterozygosity (LOH), and epigenetic events such as...

Gamma-Normal-Gamma Mixture Model for Detecting Differentially Methylated Loci in Three Breast Cancer Cell Lines (2007)

Abbas Khalili, Dustin Potter, Pearlly Yan, Lang Li, Joe Gray, Tim Huang, ...

With state-of-the-art microarray technologies now available for whole genome CpG island (CGI) methylation profiling, there is a need to develop statistical models that are specifically geared toward...

Phage display selection of efficient glutamine-donor substrate peptides for transglutaminase 2 (2006)

Keresztessy, Zsolt, Csosz, Éva, Hársfalvi, Jolán, Csomós, Krisztián, Gray, Joe, Lightowlers, Robert N., ...

Understanding substrate specificity and identification of natural targets of transglutaminase 2 (TG2), the ubiquitous multifunctional cross-linking enzyme, which forms isopeptide bonds between...

Physicochemical Limnology of Four Reservoirs in Southwest Nebraska (1967)

Tennant, Donald L., Thomas, Robert E., Thomas, Robert E., Gray, Joe

Physicochemical data from four reservoirs in Nebraska taken within a 30-hour period in August, revealed moderate thermal stratification, closely associated in two reservoirs with the functioning...

Selective Inactivation of p53 Facilitates Mouse Epithelial Tumor Progression without Chromosomal Instability

Lu, Xiangdong, Magrane, Gregg, Yin, Chaoying, Louis, David N., Gray, Joe, Van Dyke, Terry

We examined the selective pressure for, and the impact of, p53 inactivation during epithelial tumor evolution in a transgenic brain tumor model. In TgT121 mice, cell-specific inactivation of the pRb...

Selective Inactivation of p53 Facilitates Mouse Epithelial Tumor Progression without Chromosomal Instability

Lu, Xiangdong, Magrane, Gregg, Yin, Chaoying, Louis, David N., Gray, Joe, Van Dyke, Terry

We examined the selective pressure for, and the impact of, p53 inactivation during epithelial tumor evolution in a transgenic brain tumor model. In TgT121 mice, cell-specific inactivation of the pRb...

High-Resolution Mapping of Genotype-Phenotype Relationships in Cri du Chat Syndrome Using Array Comparative Genomic Hybridization

Zhang, Xiaoxiao, Snijders, Antoine, Segraves, Richard, Zhang, Xiuqing, Niebuhr, Anita, Albertson, Donna, ...

We have used array comparative genomic hybridization to map DNA copy–number changes in 94 patients with cri du chat syndrome who had been carefully evaluated for the presence of the characteristic...

Major histocompatibility class II molecules prevent destructive processing of exogenous peptides at the cell surface of macrophages for presentation to CD4 T cells

Von Delwig, Alexei, Musson, Julie A, Gray, Joe, Mckie, Norman, Robinson, John H

We studied factors affecting major histocompatibility complex class II (MHC-II)-restricted presentation of exogenous peptides at the surface of macrophages. We have previously shown that peptide...

Phage display selection of efficient glutamine-donor substrate peptides for transglutaminase 2

Keresztessy, Zsolt, Csősz, Éva, Hársfalvi, Jolán, Csomós, Krisztián, Gray, Joe, Lightowlers, Robert N., ...

Understanding substrate specificity and identification of natural targets of transglutaminase 2 (TG2), the ubiquitous multifunctional cross-linking enzyme, which forms isopeptide bonds between...

Gamma-Normal-Gamma Mixture Model for Detecting Differentially Methylated Loci in Three Breast Cancer Cell Lines

Khalili, Abbas, Potter, Dustin, Yan, Pearlly, Li, Lang, Gray, Joe, Huang, Tim, ...

With state-of-the-art microarray technologies now available for whole genome CpG island (CGI) methylation profiling, there is a need to develop statistical models that are specifically geared toward...

The Peptidoglycan Sacculus of Myxococcus xanthus Has Unusual Structural Features and Is Degraded during Glycerol-Induced Myxospore Development▿

Bui, Nhat Khai, Gray, Joe, Schwarz, Heinz, Schumann, Peter, Blanot, Didier, Vollmer, Waldemar

Upon nutrient limitation cells of the swarming soil bacterium Myxococcus xanthus form a multicellular fruiting body in which a fraction of the cells develop into myxospores. Spore development...