Johan Staaf

Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios (2008)

Staaf, Johan, Vallon-Christersson, Johan, Lindgren, David, Juliusson, Gunnar, Rosenquist, Richard, Höglund, Mattias, ...

Abstract Background Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aberrations such...

Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays (2008)

Staaf, Johan, Lindgren, David, Vallon-Christersson, Johan, Isaksson, Anders, Göransson, Hanna, Juliusson, Gunnar, ...

Abstract We present a strategy for detection of loss-of-heterozygosity and allelic imbalance in cancer cells from whole genome single nucleotide polymorphism genotyping data. Using a dilution series...

containing the (2008)

Michela Barbaro, Mikael Oscarson, Jacqueline Schoumans, Johan Staaf, Sten A Ivarsson, Corresponding Michela Barbaro

J Clin Endocrin Metab. First published ahead of print May 15, 2007 as doi:10.1210/jc.2007-0505 Isolated 46,XY gonadal dysgenesis in two sisters caused by a Xp21.2 interstitial duplication

Research Article Distinct Genomic Profiles in Hereditary Breast Tumors Identified by Array-Based Comparative Genomic Hybridization (2008)

Göran Jönsson, Tara L. Naylor, Johan Vallon-christersson, Johan Staaf, Jia Huang, M. Renee Ward, ...

Mutations in BRCA1 and BRCA2 account for a significant proportion of hereditary breast cancers. Earlier studies have shown that inherited and sporadic tumors progress along different somatic genetic...

Normalization of array-CGH data: influence of copy number imbalances (2007)

Staaf, Johan, Jönsson, Göran, Ringnér, Markus, Vallon-Christersson, Johan

Abstract Background High-resolution microarray-based comparative genomic hybridization (CGH) techniques have successfully been applied to study copy number imbalances in a number of settings such as...

Robust smooth segmentation approach for array CGH data analysis (2007)

Huang, Jian, Gusnanto, Arief, O'Sullivan, Kathleen, Staaf, Johan, Borg, Åke, Pawitan, Yudi

Motivation: Array comparative genomic hybridization (aCGH) provides a genome-wide technique to screen for copy number alteration. The existing segmentation approaches for analyzing aCGH data are...

Non-coding antisense transcription detected by conventional and single-stranded cDNA microarray (2007)

Vallon-Christersson, Johan, Staaf, Johan, Kvist, Anders, Medstrand, Patrik, Borg, Åke, Rovira, Carlos

Abstract Background Recent studies revealed that many mammalian protein-coding genes also transcribe their complementary strands. This phenomenon raises questions regarding the validity of data...

Tumor Genome Wide DNA Alterations Assessed by Array CGH in Patients with Poor and Excellent Survival Following Operation for Colorectal Cancer (2007)

Kristina K. Lagerstedt, Johan Staaf, Göran Jönsson, Elisabeth Hansson, Christina Lönnroth, Ulf Kressner, ...

Genome wide DNA alterations were evaluated by array CGH in addition to RNA expression profiling in colorectal cancer from patients with excellent and poor survival following primary operations.DNA...

Tumor Genome Wide DNA Alterations Assessed by Array CGH in Patients with Poor and Excellent Survival Following Operation for Colorectal Cancer (2007)

Kristina K. Lagerstedt, Johan Staaf, Göran Jönsson, Elisabeth Hansson, Christina Lönnroth, Ulf Kressner, ...

Genome wide DNA alterations were evaluated by array CGH in addition to RNA expression profiling in colorectal cancer from patients with excellent and poor survival following primary operations.DNA...

Continuous-index hidden Markov modelling of array CGH copy number data (2007)

Stjernqvist, Susann, Rydén, Tobias, Sköld, Martin, Staaf, Johan

Motivation: In recent years a range of techniques for analysis and segmentation of array comparative genomic hybridisation (aCGH) data has been proposed. For array designs in which clones are of...

Jämförande analys mellan svenska och portugisiska reklambyråer. : Saker som är bra att veta om man ska arbeta som grafisk formgivare i Sverige eller i Portugal (2005)

Staaf, Johan

If you move from Sweden to Portugal to work as an Art Director at an Ad agency, there are certain things you ought to know. Perhaps even before you decide to move. There are a lot of things that are...

Mapping of a Novel Ocular and Cutaneous Malignant Melanoma Susceptibility Locus to Chromosome 9q21.32 (2005)

Jönsson, Göran, Bendahl, Pär-Ola, Sandberg, Therese, Kurbasic, Azra, Staaf, Johan, Sunde, Lone, ...

An estimated 10% of all cutaneous malignant melanoma (CMM) cases are inherited, but the genetics of familial CMM are largely unknown. Ocular malignant melanoma (OMM), which is rare, may be associated...

ACID: a database for microarray clone information (2004)

Ringnér, Markus, Veerla, Srinivas, Andersson, Samuel, Staaf, Johan, Häkkinen, Jari

Summary: ACID is an online database for information about microarray cDNA clones. For each clone, the database contents include assigned UniGene cluster(s), location in the full-length transcript,...

ACID: a database for microarray clone information (2004)

Ringnér, Markus, Veerla, Srinivas, Andersson, Samuel, Staaf, Johan, Häkkinen, Jari

Summary: Array Close Information Database is an online database for information about microarray cDNA clones. For each clone, the database contents include assigned UniGene cluster(s), location in...

ACID: a database for microarray clone information (2004)

Ringnér, Markus, Veerla, Srinivas, Andersson, Samuel, Staaf, Johan, Häkkinen, Jari

Summary: ACID is an online database for information about microarray cDNA clones. For each clone, the database contents include assigned UniGene cluster(s), location in the full-length transcript,...

Recurrent 10q22-q23 Deletions: A Genomic Disorder on 10q Associated with Cognitive and Behavioral Abnormalities

Balciuniene, Jorune, Feng, Ningping, Iyadurai, Kelly, Hirsch, Betsy, Charnas, Lawrence, Bill, Brent R., ...

Low-copy repeats (LCRs) are genomic features that affect chromosome stability and can produce disease-associated rearrangements. We describe members of three families with deletions in...

Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays

Staaf, Johan, Lindgren, David, Vallon-Christersson, Johan, Isaksson, Anders, Göransson, Hanna, Juliusson, Gunnar, ...

A strategy is presented for detection of loss-of-heterozygosity and allelic imbalance in cancer cells from whole genome SNP genotyping data.

Tumor Genome Wide DNA Alterations Assessed by Array CGH in Patients with Poor and Excellent Survival Following Operation for Colorectal Cancer

Lagerstedt, Kristina K., Staaf, Johan, Jönsson, Göran, Hansson, Elisabeth, Lönnroth, Christina, Kressner, Ulf, ...

Genome wide DNA alterations were evaluated by array CGH in addition to RNA expression profiling in colorectal cancer from patients with excellent and poor survival following primary operations.